| 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              5,525
             | 
            
                                     
      $46.73 - $59.04
      $258K - $326K
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              14,406
             | 
            
                                     
      $46.79 - $60.07
      $674K - $865K
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              3,627
             | 
            
                                     
      $99.35 - $131.39
      $360K - $477K
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              59,062
             | 
            
                                     
      $7.47 - $10.9
      $441K - $644K
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              11,212
             | 
            
                                     
      $53.76 - $65.49
      $603K - $734K
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              17,080
             | 
            
                                     
      $34.79 - $46.04
      $594K - $786K
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              56,270
             | 
            
                                     
      $15.37 - $20.81
      $865K - $1.17M
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              108,076
             | 
            
                                     
      $1.7 - $3.3
      $184K - $357K
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              1,758
             | 
            
                                     
      $569.0 - $667.24
      $1M - $1.17M
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              7,042
             | 
            
                                     
      $205.61 - $235.83
      $1.45M - $1.66M
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              14,988
             | 
            
                   
      N/A
      
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              5,102
             | 
            
                                     
      $120.15 - $154.75
      $613K - $790K
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              52,765
             | 
            
                                     
      $4.59 - $7.18
      $242K - $379K
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              30,936
             | 
            
                                     
      $52.65 - $68.21
      $1.63M - $2.11M
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              89,257
             | 
            
                                     
      $10.48 - $13.23
      $935K - $1.18M
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              120,094
             | 
            
                                     
      $2.05 - $3.2
      $246K - $384K
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              2,397,104
             | 
            
                   
      N/A
      
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              102,320
             | 
            
                                     
      $18.62 - $21.55
      $1.91M - $2.2M
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              7,595
             | 
            
                                     
      $27.25 - $35.36
      $207K - $269K
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              11,458
             | 
            
                                     
      $100.05 - $114.0
      $1.15M - $1.31M
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              5,965
             | 
            
                                     
      $123.53 - $180.57
      $737K - $1.08M
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              7,209
             | 
            
                                     
      $129.11 - $186.42
      $931K - $1.34M
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              64,237
             | 
            
                                     
      $9.45 - $15.79
      $607K - $1.01M
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              12,915
             | 
            
                                     
      $19.46 - $25.22
      $251K - $326K
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              18,869
             | 
            
                   
      N/A
      
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              4,767
             | 
            
                                     
      $147.79 - $185.09
      $705K - $882K
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              24,947
             | 
            
                                     
      $62.93 - $84.99
      $1.57M - $2.12M
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              319,010
             | 
            
                                     
      $2.88 - $4.18
      $919K - $1.33M
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              48,135
             | 
            
                                     
      $68.16 - $81.31
      $3.28M - $3.91M
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              7,946
             | 
            
                                     
      $51.22 - $92.58
      $407K - $736K
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              32,169
             | 
            
                                     
      $47.83 - $63.17
      $1.54M - $2.03M
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              55,613
             | 
            
                                     
      $11.79 - $14.27
      $656K - $794K
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              19,830
             | 
            
                                     
      $109.09 - $133.32
      $2.16M - $2.64M
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              21,818
             | 
            
                                     
      $42.12 - $47.28
      $919K - $1.03M
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              4,132
             | 
            
                   
      N/A
      
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              53,670
             | 
            
                                     
      $9.26 - $11.68
      $497K - $627K
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            
              
                  
    
      
     
    
      Marinus Pharmaceuticals Inc
     
   
               
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              101,921
             | 
            
                   
      N/A
      
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              16,080
             | 
            
                   
      N/A
      
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              21,499
             | 
            
                                     
      $59.45 - $83.9
      $1.28M - $1.8M
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              407,131
             | 
            
                                     
      $3.08 - $4.67
      $1.25M - $1.9M
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              15,557
             | 
            
                                     
      $9.06 - $10.2
      $141K - $159K
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              30,667
             | 
            
                                     
      $42.71 - $55.05
      $1.31M - $1.69M
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              90,749
             | 
            
                                     
      $3.4 - $5.28
      $309K - $479K
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              58,256
             | 
            
                                     
      $16.85 - $21.9
      $982K - $1.28M
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              26,814
             | 
            
                                     
      $45.95 - $57.2
      $1.23M - $1.53M
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              32,642
             | 
            
                   
      N/A
      
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              35,183
             | 
            
                   
      N/A
      
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              5,624
             | 
            
                                     
      $38.3 - $50.37
      $215K - $283K
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              21,560
             | 
            
                                     
      $9.03 - $19.13
      $195K - $412K
     
                  
             | 
            
              
                
              
             |           
          
          
          
          
            | 
              
             | 
            
              
                
                  Q4 2021
                  Filed on Feb 14, 2022
                                       
                    
             | 
            
              4,037
             | 
            
                                     
      $156.0 - $265.78
      $630K - $1.07M
     
                  
             | 
            
              
                
              
             |