Simplex Trading, LLC Biotechnology

Simplex Trading, LLC

$175 Billion
Q2 2025

Stock List

Stock	Market Cap.	Holding Value (Reported)	# of Shares.	Last Trade	Trade History
DYAI Dyadic International Inc	$24.2M	$1,000 0.0% of portfolio	1,999	Q2 2025 New
EQ Equillium, Inc.	$31.9M	$1,000 0.0% of portfolio	5,075	Q2 2025 Added 239.46%
IMCR Immunocore Holdings PLC	$1.4B	$1,000 0.0% of portfolio	54	Q2 2025 New
PRQR Pro Qr Therapeutics N.V.	$136M	$1,000 0.0% of portfolio	856	Q2 2025 Reduced 79.16%
RLMD Relmada Therapeutics, Inc.	$16.9M	$1,000 0.0% of portfolio	2,427	Q2 2025 Reduced 45.85%
ACET Adicet Bio, Inc.	$25.6M	$0 0.0% of portfolio	583	Q2 2025 Reduced 68.57%
ACIU Ac Immune Sa	$179M	$0 0.0% of portfolio	318	Q2 2025 Added 11.97%
CDXS Codexis, Inc.	$187M	$0 0.0% of portfolio	213	Q2 2025 New
CLGN Coll Plant Biotechnologies LTD	$34.9M	$0 0.0% of portfolio	93	Q2 2025 New
CLSD Clearside Biomedical, Inc.	$25.9M	$0 0.0% of portfolio	127	Q2 2025 New
FHTX Foghorn Therapeutics Inc.	$203M	$0 0.0% of portfolio	160	Q2 2025 Reduced 91.02%
GHRS Gh Research PLC	$632M	$0 0.0% of portfolio	25	Q2 2025 Added 47.06%
IMMP Immutep LTD	$147M	$0 0.0% of portfolio	61	Q2 2025 Added 19.61%
ADGI Adagio Therapeutics, Inc.	$505M	$0 0.0% of portfolio	1,180	Q2 2025 New
NAUT Nautilus Biotechnology, Inc.	$88.5M	$0 0.0% of portfolio	115	Q2 2025 New
NXTC Next Cure, Inc.	$134M	$0 0.0% of portfolio	920	Q2 2025 New
PMVP Pmv Pharmaceuticals, Inc.	$64.8M	$0 0.0% of portfolio	71	Q2 2025 New
ENOB Enochian Biosciences Inc	$244M	$0 0.0% of portfolio	600	Q2 2025 Reduced 17.81%
STTK Shattuck Labs, Inc.	$32.2M	$0 0.0% of portfolio	1,156	Q2 2025 New
VCYT Veracyte, Inc.	$2.06B	$0 0.0% of portfolio	21	Q2 2025 New
VYGR Voyager Therapeutics, Inc.	$131M	$0 0.0% of portfolio	280	Q2 2025 Reduced 89.6%

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