Two Sigma Investments, LP Reduced Holdings in Q2 2025

Two Sigma Investments, LP

  • $50.6 Billion
  • Q2 2025
Stock Shares change Price Range Shares Held Trade History
BCAB
Bio Atla, Inc.

Healthcare
-106K
- 56.18%
$0.27 - $0.56 $28.6K - $59.3K
82.6K $33K
TRST
Trustco Bank Corp N Y

Financial Services
-8.18K
- 9.95%
$27.56 - $33.42 $225K - $273K
74.1K $2.47M
CRMT
Americas Carmart Inc

Consumer Cyclical
-5.39K
- 21.15%
$43.5 - $57.74 $235K - $311K
20.1K $1.13M
CRTX
Cortexyme, Inc.

Healthcare
-23.8K
- 57.75%
N/A
17.4K $22K
MTLS
Materialise Nv

Technology
-12.7K
- 21.98%
$4.16 - $5.89 $52.6K - $74.5K
44.9K $253K
ABUS
Arbutus Biopharma Corp

Healthcare
-6.99K
- 38.21%
$2.88 - $3.61 $20.1K - $25.2K
11.3K $34K
FMS
Fresenius Medical Care Ag & Co. K Ga A

Healthcare
-4.17K
- 16.81%
$22.56 - $29.85 $94.1K - $125K
20.6K $589K
LVTX
Lava Therapeutics Nv

Healthcare
-23.3K
- 40.38%
$1.08 - $1.4 $25.2K - $32.6K
34.4K $45K
ONL
Orion Office Reit Inc.

Real Estate
-12.7K
- 21.09%
$1.52 - $2.43 $19.2K - $30.8K
47.4K $100K
FULC
Fulcrum Therapeutics, Inc.

Healthcare
-91.3K
- 60.76%
$2.51 - $7.38 $229K - $674K
59K $405K
NUGO
Nushares ETF Tr Growth Opportu

ETFs
-2.4K
- 21.05%
$27.15 - $36.01 $65.2K - $86.4K
9K $324K
ABOS
Acumen Pharmaceuticals, Inc.

Healthcare
-31.5K
- 13.56%
$0.9 - $1.27 $28.4K - $40K
201K $232K
CGEN
Compugen LTD

Healthcare
-54.8K
- 23.46%
$1.18 - $1.79 $64.7K - $98.2K
179K $318K
JOB
Gee Group Inc.

Industrials
-111K
- 47.27%
$0.18 - $0.21 $20K - $23.3K
124K $24K
IKNA
Ikena Oncology, Inc.

Healthcare
-20.5K
- 25.77%
$1.03 - $1.47 $21.1K - $30.1K
59K $79K
KBWR
Invesco ETF Tr Ii Kbw Regional

ETFs
-500
- 10.87%
$48.45 - $58.65 $24.2K - $29.3K
4.1K $236K
RLYB
Rallybio Corp

Healthcare
-2.93K
- 4.38%
$0.25 - $0.61 $731 - $1.78K
63.8K $21K
PWOD
Penns Woods Bancorp Inc

Financial Services
-1.6K
- 14.2%
$25.36 - $30.55 $40.6K - $48.8K
9.66K $293K
STTK
Shattuck Labs, Inc.

Healthcare
-8.3K
- 9.74%
$0.73 - $1.3 $6.06K - $10.8K
76.9K $60K
SIXS
Exchange Traded Concepts Tr Et

ETFs
-400
- 6.25%
$41.97 - $47.37 $16.8K - $18.9K
6K $280K
SND
Smart Sand, Inc.

Energy
-409
- 1.26%
$1.81 - $2.56 $740 - $1.05K
32K $64K
AXTI
Axt Inc

Technology
-94.3K
- 35.9%
$1.16 - $2.35 $109K - $222K
168K $352K
MNSB
Main Street Bancshares, Inc.

Financial Services
-2.73K
- 17.67%
$15.27 - $19.85 $41.7K - $54.2K
12.7K $240K
REGL
Proshares Tr S&P Midcap 400 Di

ETFs
-700
- 1.59%
$72.71 - $82.56 $50.9K - $57.8K
43.2K $3.52M
STRA
Strategic Education, Inc.

Consumer Defensive
-253
- 9.1%
$77.09 - $92.26 $19.5K - $23.3K
2.53K $215K
BPT
Bp Prudhoe Bay Royalty Trust

Energy
-22.6K
- 22.47%
$0.5 - $0.79 $11.3K - $17.8K
77.9K $38K
CSTE
Caesarstone Ltd.

Industrials
-4.41K
- 24.89%
$1.7 - $3.15 $7.5K - $13.9K
13.3K $26K
CSAN
Cosan S.A.

Energy
-2.6K
- 11.48%
$4.44 - $6.16 $11.5K - $16K
20K $101K
LCNB
Lcnb Corp

Financial Services
-944
- 7.38%
$13.64 - $15.65 $12.9K - $14.8K
11.9K $172K
TGLS
Tecnoglass Inc.

Basic Materials
-6.9K
- 7.76%
$62.7 - $88.42 $433K - $610K
82.1K $6.35M
PRLD
Prelude Therapeutics Inc

Healthcare
-28.7K
- 15.62%
$0.61 - $1.18 $17.5K - $33.9K
155K $125K
SB
Safe Bulkers, Inc.

Industrials
-1.94K
- 1.83%
$3.05 - $3.88 $5.92K - $7.53K
104K $375K
TOP
Zhong Yang Financial Group LTD

Financial Services
-12.1K
- 20.64%
$1.04 - $1.38 $12.6K - $16.7K
46.6K $57K
PSNL
Personalis, Inc.

Healthcare
-53.3K
- 48.38%
$3.0 - $6.57 $160K - $350K
56.9K $373K
VLGEA
Village Super Market Inc

Consumer Defensive
-783
- 2.23%
$34.78 - $40.13 $27.2K - $31.4K
34.4K $1.32M
VRAR
Glimpse Group, Inc.

Technology
-11.5K
- 23.32%
N/A
37.9K $37K
OMFS
Invesco Exchange Traded Self I

ETFs
-1.4K
- 6.57%
$33.88 - $40.17 $47.4K - $56.2K
19.9K $797K
GGR
Gogoro Inc.

Consumer Cyclical
-42.1K
- 35.07%
$0.2 - $0.38 $8.42K - $16K
77.9K $21K
VRCA
Verrica Pharmaceuticals Inc.

Healthcare
-1.38K
- 1.56%
N/A
87.3K $693K
HGTY
Hagerty, Inc.

Financial Services
-11.3K
- 11.64%
$8.34 - $10.18 $94.3K - $115K
85.8K $867K
III
Information Services Group Inc.

Technology
-29.2K
- 19.89%
$3.45 - $4.96 $101K - $145K
118K $564K
MTEK
Maris Tech Ltd.

Technology
-9.68K
- 47.82%
$1.77 - $3.43 $17.1K - $33.2K
10.6K $33K
BGFV
Big 5 Sporting Goods Corp

Consumer Cyclical
-24.7K
- 42.22%
$0.81 - $1.53 $20K - $37.8K
33.8K $48K
TCX
Tucows Inc

Technology
-2.32K
- 17.49%
$14.28 - $20.26 $33.1K - $46.9K
10.9K $215K
PRLB
Proto Labs Inc

Industrials
-1K
- 15.15%
$31.12 - $41.64 $31.1K - $41.6K
5.6K $224K
HOWL
Werewolf Therapeutics, Inc.

Healthcare
-12.7K
- 21.86%
$0.63 - $1.42 $8.01K - $18K
45.4K $49K
XLO
Xilio Therapeutics, Inc.

Healthcare
-6.04K
- 7.18%
$0.65 - $1.15 $3.92K - $6.94K
78K $53K
ADGI
Adagio Therapeutics, Inc.

Healthcare
-1.92K
- 0.8%
N/A
239K $790K
SILC
Silicom Ltd.

Technology
-1.3K
- 5.2%
$12.83 - $15.9 $16.6K - $20.6K
23.6K $365K
Activity Summary
Buys All Purchases 1753 New Holdings 545 Increased Positions 1208 Sells All Sells 1267 Reductions 1267 Sold out 0 Options Calls 3 Puts 26
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