The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
4D MOLECULAR THERAPEUTICS IN COM 35104E100   3,397,143 609,900 SH   SOLE   609,900 0 0
89BIO INC COM 282559103   50,659,907 6,478,249 SH   SOLE   6,478,249 0 0
ABIVAX SA SPONSORED ADS 00370M103   26,199,810 3,579,209 SH   SOLE   3,579,209 0 0
AKERO THERAPEUTICS INC COM 00973Y108   41,451,800 1,490,000 SH   SOLE   1,490,000 0 0
ALIGOS THERAPEUTICS INC COM NEW 01626L204   9,725,342 244,110 SH   SOLE   244,110 0 0
ALLAKOS INC COM 01671P100   6,902,181 5,704,282 SH   SOLE   5,704,282 0 0
ANI PHARMACEUTICALS INC COM 00182C103   35,879,042 649,042 SH   SOLE   649,042 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106   136,412,729 4,274,921 SH   SOLE   4,274,921 0 0
AUTOLUS THERAPEUTICS PLC SPON ADS 05280R100   33,414,422 14,218,903 SH   SOLE   14,218,903 0 0
AVALO THERAPEUTICS INC COM NEW 05338F306   6,441,810 867,000 SH   SOLE   867,000 0 0
BICARA THERAPEUTICS INC COM 055477103   34,840,000 2,000,000 SH   SOLE   2,000,000 0 0
BICYCLE THERAPEUTICS PLC SPONSORED ADS 088786108   17,865,134 1,276,081 SH   SOLE   1,276,081 0 0
BRIDGEBIO PHARMA INC COM 10806X102   22,477,805 819,162 SH   SOLE   819,162 0 0
CASSAVA SCIENCES INC COM 14817C107   1,180,000 500,000 SH Put SOLE   500,000 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202   38,919,136 1,540,132 SH   SOLE   1,540,132 0 0
CENTESSA PHARMACEUTICALS PLC SPONSORED ADS 152309100   22,612,500 1,350,000 SH   SOLE   1,350,000 0 0
CLIMB BIO INC COM 28658R106   1,872,207 1,040,115 SH   SOLE   1,040,115 0 0
CONTEXT THERAPEUTICS INC COM 21077P108   7,790,323 7,419,355 SH   SOLE   7,419,355 0 0
CYBIN INC COM NEW 23256X407   13,494,485 1,529,987 SH   SOLE   1,529,987 0 0
CYTOKINETICS INC COM NEW 23282W605   117,600,000 2,500,000 SH   SOLE   2,500,000 0 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201   227,197,276 17,791,486 SH   SOLE   17,791,486 0 0
DYNE THERAPEUTICS INC COM 26818M108   47,120,000 2,000,000 SH   SOLE   2,000,000 0 0
EDGEWISE THERAPEUTICS INC COM 28036F105   18,968,241 710,421 SH   SOLE   710,421 0 0
ENGENE HOLDINGS INC COM 29286M105   30,307,874 4,557,575 SH   SOLE   4,557,575 0 0
GALAPAGOS NV SPON ADR 36315X101   21,471,395 780,778 SH   SOLE   780,778 0 0
GENMAB A/S SPONSORED ADS 372303206   41,740,000 2,000,000 SH   SOLE   2,000,000 0 0
GERON CORP COM 374163103   14,199,956 4,011,287 SH   SOLE   4,011,287 0 0
GUARDANT HEALTH INC COM 40131M109   196,117,741 6,419,566 SH   SOLE   6,419,566 0 0
HARMONY BIOSCIENCES HLDGS IN COM 413197104   49,894,500 1,450,000 SH   SOLE   1,450,000 0 0
IMMUNOCORE HLDGS PLC ADS 45258D105   15,321,592 519,376 SH   SOLE   519,376 0 0
IMMUNOVANT INC COM 45258J102   148,620,000 6,000,000 SH   SOLE   6,000,000 0 0
INOVIO PHARMACEUTICALS INC COM SHS 45773H409   5,708,066 3,119,162 SH   SOLE   3,119,162 0 0
INTRA-CELLULAR THERAPIES INC COM 46116X101   167,040,000 2,000,000 SH   SOLE   2,000,000 0 0
INVIVYD INC COM 00534A102   4,736,563 10,689,603 SH   SOLE   10,689,603 0 0
IONIS PHARMACEUTICALS INC COM 462222100   67,610,123 1,933,928 SH   SOLE   1,933,928 0 0
KORRO BIO INC COM 500946108   33,296,555 874,614 SH   SOLE   874,614 0 0
MBX BIOSCIENCES INC COM 55287L101   55,638,972 3,018,935 SH   SOLE   3,018,935 0 0
MIND MEDICINE MINDMED INC COM NEW 60255C885   19,603,494 2,816,594 SH   SOLE   2,816,594 0 0
NEKTAR THERAPEUTICS COM 640268108   1,837,678 1,975,998 SH   SOLE   1,975,998 0 0
NEUMORA THERAPEUTICS INC. COM 640979100   12,611,880 1,189,800 SH Call SOLE   1,189,800 0 0
NEUMORA THERAPEUTICS INC. COM 640979100   42,400,000 4,000,000 SH   SOLE   4,000,000 0 0
NOVAVAX INC COM NEW 670002401   16,080,000 2,000,000 SH   SOLE   2,000,000 0 0
NURIX THERAPEUTICS INC COM 67080M103   56,520,000 3,000,000 SH   SOLE   3,000,000 0 0
OCULAR THERAPEUTIX INC COM 67576A100   109,621,848 12,836,282 SH   SOLE   12,836,282 0 0
OLEMA PHARMACEUTICALS INC COM 68062P106   20,071,716 3,442,833 SH   SOLE   3,442,833 0 0
ONKURE THERAPEUTICS INC COM CL A 68277Q105   4,506,305 523,989 SH   SOLE   523,989 0 0
ORUKA THERAPEUTICS INC COM 687604108   14,542,500 750,000 SH   SOLE   750,000 0 0
PLIANT THERAPEUTICS INC COM 729139105   78,654,625 5,972,257 SH   SOLE   5,972,257 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102   38,600,000 1,000,000 SH   SOLE   1,000,000 0 0
RAPT THERAPEUTICS INC COM 75382E109   9,497,980 6,011,380 SH   SOLE   6,011,380 0 0
REGULUS THERAPEUTICS INC COM 75915K309   5,154,851 3,262,564 SH   SOLE   3,262,564 0 0
SEPTERNA INC COM 81734D104   43,806,074 1,912,929 SH   SOLE   1,912,929 0 0
SPRINGWORKS THERAPEUTICS INC COM 85205L107   125,037,114 3,460,756 SH   SOLE   3,460,756 0 0
SPYRE THERAPEUTICS INC COM NEW 00773J202   5,098,669 219,015 SH   SOLE   219,015 0 0
STRUCTURE THERAPEUTICS INC SPONSORED ADS 86366E106   75,936,000 2,800,000 SH   SOLE   2,800,000 0 0
TERNS PHARMACEUTICALS INC COM 880881107   30,894,131 5,576,558 SH   SOLE   5,576,558 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108   27,493,292 653,513 SH   SOLE   653,513 0 0
UPSTREAM BIO INC COM 91678A107   16,440,000 1,000,000 SH   SOLE   1,000,000 0 0
VERONA PHARMA PLC SPONSORED ADS 925050106   39,474,000 850,000 SH   SOLE   850,000 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104   86,700,945 4,522,741 SH   SOLE   4,522,741 0 0
XENCOR INC COM 98401F105   11,490,000 500,000 SH   SOLE   500,000 0 0
XENON PHARMACEUTICALS INC COM 98420N105   6,629,974 169,132 SH   SOLE   169,132 0 0
ZURA BIO LTD CLASS A ORD SHS G9TY5A101   8,209,458 3,283,783 SH   SOLE   3,283,783 0 0