The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
3D Systems Corp Common / Ordinary Stock 88554D205 261 37,425 SH   DFND 1 37,425 0 0
3M Co Common / Ordinary Stock 88579Y101 3,422 21,941 SH   DFND 1,2 21,941 0 0
Abbott Laboratories Common / Ordinary Stock 002824100 5,986 65,473 SH   DFND 1,2,3 65,473 0 0
AbbVie Inc Common / Ordinary Stock 00287Y109 11,116 113,224 SH   DFND 1,2,4 113,224 0 0
ABIOMED Inc Common / Ordinary Stock 003654100 595 2,464 SH   DFND 2,4 2,464 0 0
ACADIA Pharmaceuticals Inc Common / Ordinary Stock 004225108 242 5,000 SH   DFND 2 5,000 0 0
ACI Worldwide Inc Common / Ordinary Stock 004498101 269 10,000 SH   DFND 2 10,000 0 0
Activision Blizzard Inc Common / Ordinary Stock 00507V109 7,568 99,718 SH   DFND 1,2,3,5 99,718 0 0
Adamas Pharmaceuticals Inc Common / Ordinary Stock 00548A106 256 100,000 SH   DFND 2 100,000 0 0
Adobe Inc Common / Ordinary Stock 00724F101 26,734 61,414 SH   DFND 1,2,3,4,5 61,414 0 0
Advanced Micro Devices Inc Common / Ordinary Stock 007903107 11,951 227,181 SH   DFND 1,2,3,4,5 227,181 0 0
AES Corp/VA Common / Ordinary Stock 00130H105 802 55,368 SH   DFND 2 55,368 0 0
Aflac Inc Common / Ordinary Stock 001055102 443 12,297 SH   DFND 2 12,297 0 0
AGCO Corp Common / Ordinary Stock 001084102 2,847 51,339 SH   DFND 2,3 51,339 0 0
Agile Therapeutics Inc Common / Ordinary Stock 00847L100 278 100,000 SH   DFND 2 100,000 0 0
Agilent Technologies Inc Common / Ordinary Stock 00846U101 1,714 19,402 SH   DFND 1,2 19,402 0 0
AGNC Investment Corp Closed-end REIT 00123Q104 259 20,132 SH   DFND 1 20,132 0 0
Agnico Eagle Mines Ltd Common / Ordinary Stock 008474108 233 3,652 SH   DFND 1 3,652 0 0
Aileron Therapeutics Inc Common / Ordinary Stock 00887A105 1,008 854,250 SH   DFND 2 854,250 0 0
Air Products and Chemicals Inc Common / Ordinary Stock 009158106 913 3,785 SH   DFND 2 3,785 0 0
Akamai Technologies Inc Common / Ordinary Stock 00971T101 1,177 10,992 SH   DFND 2,3 10,992 0 0
Akebia Therapeutics Inc Common / Ordinary Stock 00972D105 407 30,000 SH   DFND 2 30,000 0 0
Alcon Inc Common / Ordinary Stock H01301128 2,043 35,627 SH   DFND 1,2 35,627 0 0
Aldeyra Therapeutics Inc Common / Ordinary Stock 01438T106 1,308 313,889 SH   DFND 2 313,889 0 0
Alexandria Real Estate Equities Inc Closed-end REIT 015271109 350 2,163 SH   DFND 2 2,163 0 0
Alexion Pharmaceuticals Inc Common / Ordinary Stock 015351109 1,583 14,109 SH   DFND 1,2,4 14,109 0 0
Algonquin Power & Utilities Corp Common / Ordinary Stock 015857105 544 42,113 SH   DFND 2 42,113 0 0
Alibaba Group Holding Ltd American Depository Receipts ADR 01609W102 48,468 224,703 SH   DFND 1,2,7 224,703 0 0
Align Technology Inc Common / Ordinary Stock 016255101 1,956 7,130 SH   DFND 1,2 7,130 0 0
Allena Pharmaceuticals Inc Common / Ordinary Stock 018119107 1,179 746,804 SH   DFND 2 746,804 0 0
Alliance Data Systems Corp Common / Ordinary Stock 018581108 1,418 31,438 SH   DFND 1 31,438 0 0
Alliant Energy Corp Common / Ordinary Stock 018802108 204 4,275 SH   DFND 2 4,275 0 0
Allstate Corp/The Common / Ordinary Stock 020002101 692 7,142 SH   DFND 1,2 7,142 0 0
Alphabet Inc Common / Ordinary Stock 02079K107 47,543 33,633 SH   DFND 1,2,3,4,5 33,633 0 0
Alphabet Inc Common / Ordinary Stock 02079K305 72,397 51,054 SH   DFND 1,2,3,4,5,7 51,054 0 0
Altice USA Inc Common / Ordinary Stock 02156K103 761 33,774 SH   DFND 4 33,774 0 0
Altria Group Inc Common / Ordinary Stock 02209S103 2,839 72,356 SH   DFND 1,2 72,356 0 0
Amarin Corp PLC American Depository Receipts ADR 023111206 2,108 304,654 SH   DFND 2 304,654 0 0
Amazon.com Inc Common / Ordinary Stock 023135106 96,260 34,892 SH   DFND 1,2,4,5,7 34,892 0 0
Ambev SA American Depository Receipts ADR 02319V103 1,235 468,117 SH   DFND 1 468,117 0 0
Ameren Corp Common / Ordinary Stock 023608102 297 4,232 SH   DFND 2 4,232 0 0
America Movil SAB de CV American Depository Receipts ADR 02364W105 165 13,032 SH   DFND 1 13,032 0 0
American Airlines Group Inc Common / Ordinary Stock 02376R102 374 28,649 SH   DFND 1,2,6 28,649 0 0
American Electric Power Co Inc Common / Ordinary Stock 025537101 684 8,591 SH   DFND 1,2 8,591 0 0
American Express Co Common / Ordinary Stock 025816109 3,345 35,146 SH   DFND 1,2,7 35,146 0 0
American International Group Inc Common / Ordinary Stock 026874784 1,352 43,372 SH   DFND 1,2 43,372 0 0
American Tower Corp Closed-end REIT 03027X100 3,006 11,629 SH   DFND 1,2 11,629 0 0
American Water Works Co Inc Common / Ordinary Stock 030420103 2,290 17,800 SH   DFND 2 17,800 0 0
Ameriprise Financial Inc Common / Ordinary Stock 03076C106 1,568 10,454 SH   DFND 2,4 10,454 0 0
AmerisourceBergen Corp Common / Ordinary Stock 03073E105 1,486 14,748 SH   DFND 2 14,748 0 0
Ametek Inc Common / Ordinary Stock 031100100 2,676 29,950 SH   DFND 2,3 29,950 0 0
Amgen Inc Common / Ordinary Stock 031162100 5,431 23,028 SH   DFND 1,2,5 23,028 0 0
Amicus Therapeutics Inc Common / Ordinary Stock 03152W109 904 60,000 SH   DFND 2 60,000 0 0
Amphenol Corp Common / Ordinary Stock 032095101 3,704 38,666 SH   DFND 2,3,4 38,666 0 0
Amyris Inc Common / Ordinary Stock 03236M200 213 50,000 SH   DFND 2 50,000 0 0
Analog Devices Inc Common / Ordinary Stock 032654105 5,836 47,590 SH   DFND 1,2,3,4,5 47,590 0 0
ANGI Homeservices Inc Common / Ordinary Stock 00183L102 182 15,000 SH   DFND 2 15,000 0 0
AngloGold Ashanti Ltd American Depository Receipts ADR 035128206 713 24,191 SH   DFND 1 24,191 0 0
ANSYS Inc Common / Ordinary Stock 03662Q105 4,020 13,781 SH   DFND 2,3 13,781 0 0
Anthem Inc Common / Ordinary Stock 036752103 3,347 12,728 SH   DFND 1,2 12,728 0 0
Apollo Global Management Inc Common / Ordinary Stock 03768E105 1,226 24,579 SH   DFND 2 24,579 0 0
Apple Inc Common / Ordinary Stock 037833100 164,950 452,167 SH   DFND 1,2,3,4,5 452,167 0 0
Applied Genetic Technologies Corp/DE Common / Ordinary Stock 03820J100 221 40,000 SH   DFND 2 40,000 0 0
Applied Materials Inc Common / Ordinary Stock 038222105 12,708 210,231 SH   DFND 1,2,3,5 210,231 0 0
Aquestive Therapeutics Inc Common / Ordinary Stock 03843E104 196 40,512 SH   DFND 2 40,512 0 0
Aramark Common / Ordinary Stock 03852U106 949 42,084 SH   DFND 2 42,084 0 0
Archer-Daniels-Midland Co Common / Ordinary Stock 039483102 4,394 110,131 SH   DFND 1,2,3 110,131 0 0
Ardmore Shipping Corp Common / Ordinary Stock Y0207T100 513 118,299 SH   DFND 2 118,299 0 0
Arthur J Gallagher & Co Common / Ordinary Stock 363576109 316 3,250 SH   DFND 2 3,250 0 0
AT&T Inc Common / Ordinary Stock 00206R102 20,185 667,746 SH   DFND 1,2,3 667,746 0 0
Athene Holding Ltd Common / Ordinary Stock G0684D107 1,184 37,964 SH   DFND 2 37,964 0 0
Athersys Inc Common / Ordinary Stock 04744L106 1,104 400,000 SH   DFND 2 400,000 0 0
Atmos Energy Corp Common / Ordinary Stock 049560105 208 2,096 SH   DFND 2 2,096 0 0
Autodesk Inc Common / Ordinary Stock 052769106 4,545 19,002 SH   DFND 1,2,3,4,5 19,002 0 0
Automatic Data Processing Inc Common / Ordinary Stock 053015103 7,660 51,454 SH   DFND 2,3,5 51,454 0 0
AutoZone Inc Common / Ordinary Stock 053332102 451 400 SH   DFND 2 400 0 0
AvalonBay Communities Inc Closed-end REIT 053484101 1,432 9,266 SH   DFND 2 9,266 0 0
AVEO Pharmaceuticals Inc Common / Ordinary Stock 053588307 257 50,000 SH   DFND 2 50,000 0 0
Axovant Gene Therapies Ltd Common / Ordinary Stock G0750W203 141 50,000 SH   DFND 2 50,000 0 0
Azul SA American Depository Receipts ADR 05501U106 564 50,484 SH   DFND 2,4 50,484 0 0
B2Gold Corp Common / Ordinary Stock 11777Q209 446 78,553 SH   DFND 2 78,553 0 0
Baidu Inc American Depository Shares - ADS 056752108 12,122 101,113 SH   DFND 1,2,5,7 101,113 0 0
Baker Hughes Co Common / Ordinary Stock 05722G100 718 46,712 SH   DFND 2 46,712 0 0
Ball Corp Common / Ordinary Stock 058498106 3,689 53,098 SH   DFND 2,3 53,098 0 0
Banco Bradesco SA American Depository Receipts ADR 059460303 7,729 2,028,853 SH   DFND 1,2 2,028,853 0 0
Bank of America Corp Common / Ordinary Stock 060505104 9,038 380,553 SH   DFND 1,2,7 380,553 0 0
Bank of Montreal Common / Ordinary Stock 063671101 267 5,045 SH   DFND 1 5,045 0 0
Bank of New York Mellon Corp/The Common / Ordinary Stock 064058100 1,441 37,295 SH   DFND 1,2 37,295 0 0
Bank of Nova Scotia/The Common / Ordinary Stock 064149107 1,212 29,405 SH   DFND 1,2 29,405 0 0
Baozun Inc American Depository Receipts ADR 06684L103 248 6,470 SH   DFND 2,7 6,470 0 0
Baxter International Inc Common / Ordinary Stock 071813109 5,432 63,101 SH   DFND 1,2,3,4 63,101 0 0
Baytex Energy Corp Common / Ordinary Stock 07317Q105 37 74,340 SH   DFND 1 74,340 0 0
BCE Inc Common / Ordinary Stock 05534B760 3,415 82,161 SH   DFND 1,2 82,161 0 0
Becton Dickinson and Co Common / Ordinary Stock 075887109 2,888 12,074 SH   DFND 2,3 12,074 0 0
Bed Bath & Beyond Inc Common / Ordinary Stock 075896100 190 18,015 SH   DFND 1 18,015 0 0
Berkshire Hathaway Inc Common / Ordinary Stock 084670702 12,717 71,241 SH   DFND 1,2 71,241 0 0
Best Buy Co Inc Common / Ordinary Stock 086516101 2,376 27,234 SH   DFND 2 27,234 0 0
Beyond Meat Inc Common / Ordinary Stock 08862E109 1,440 10,751 SH   DFND 2 10,751 0 0
BioCryst Pharmaceuticals Inc Common / Ordinary Stock 09058V103 461 96,800 SH   DFND 2 96,800 0 0
Biogen Inc Common / Ordinary Stock 09062X103 5,226 19,534 SH   DFND 1,2,4,5 19,534 0 0
BioMarin Pharmaceutical Inc Common / Ordinary Stock 09061G101 2,703 21,919 SH   DFND 1,2,7 21,919 0 0
Bioxcel Therapeutics Inc Common / Ordinary Stock 09075P105 1,132 21,360 SH   DFND 2 21,360 0 0
Black Knight Inc Common / Ordinary Stock 09215C105 1,643 22,650 SH   DFND 2,3 22,650 0 0
Blackberry Ltd Common / Ordinary Stock 09228F103 198 40,755 SH   DFND 1 40,755 0 0
BlackRock Inc Common / Ordinary Stock 09247X101 2,656 4,882 SH   DFND 1,2 4,882 0 0
Blackstone Group Inc/The Common / Ordinary Stock 09260D107 746 13,171 SH   DFND 1,2 13,171 0 0
Boeing Co/The Common / Ordinary Stock 097023105 5,157 28,135 SH   DFND 1,2 28,135 0 0
Booking Holdings Inc Common / Ordinary Stock 09857L108 5,409 3,397 SH   DFND 1,2,4,5 3,397 0 0
Booz Allen Hamilton Holding Corp Common / Ordinary Stock 099502106 667 8,581 SH   DFND 4 8,581 0 0
BorgWarner Inc Common / Ordinary Stock 099724106 1,360 38,555 SH   DFND 2 38,555 0 0
Boston Properties Inc Closed-end REIT 101121101 223 2,476 SH   DFND 2 2,476 0 0
Boston Scientific Corp Common / Ordinary Stock 101137107 3,756 106,984 SH   DFND 1,2,4 106,984 0 0
BP PLC American Depository Receipts ADR 055622104 1,529 65,581 SH   DFND 1 65,581 0 0
BRF SA American Depository Receipts ADR 10552T107 532 134,079 SH   DFND 1 134,079 0 0
Bright Horizons Family Solutions Inc Common / Ordinary Stock 109194100 566 4,834 SH   DFND 2 4,834 0 0
Bristol-Myers Squibb Co Common / Ordinary Stock 110122108 5,747 97,749 SH   DFND 1,2,4 97,749 0 0
Broadcom Inc Common / Ordinary Stock 11135F101 17,151 54,344 SH   DFND 1,2,3,4,5 54,344 0 0
Broadridge Financial Solutions Inc Common / Ordinary Stock 11133T103 2,740 21,720 SH   DFND 2,3 21,720 0 0
Brookfield Infrastructure Partners LP Master Limited Partnership G16252101 457 11,145 SH   DFND 2 11,145 0 0
Brunswick Corp/DE Common / Ordinary Stock 117043109 1,374 21,477 SH   DFND 2 21,477 0 0
Cable One Inc Common / Ordinary Stock 12685J105 1,556 877 SH   DFND 2 877 0 0
CACI International Inc Common / Ordinary Stock 127190304 526 2,428 SH   DFND 2 2,428 0 0
Cadence Design Systems Inc Common / Ordinary Stock 127387108 3,223 33,587 SH   DFND 2,3 33,587 0 0
Campbell Soup Co Common / Ordinary Stock 134429109 1,018 20,525 SH   DFND 2 20,525 0 0
Canadian Imperial Bank of Commerce Common / Ordinary Stock 136069101 1,873 28,115 SH   DFND 1,2 28,115 0 0
Canadian National Railway Co Common / Ordinary Stock 136375102 2,012 22,822 SH   DFND 2 22,822 0 0
Canadian Pacific Railway Ltd Common / Ordinary Stock 13645T100 2,535 10,000 SH   DFND 2 10,000 0 0
Canopy Growth Corp Common / Ordinary Stock 138035100 1,400 86,750 SH   DFND 1,2 86,750 0 0
Capital One Financial Corp Common / Ordinary Stock 14040H105 601 9,607 SH   DFND 1,2 9,607 0 0
Cardinal Health Inc Common / Ordinary Stock 14149Y108 261 5,005 SH   DFND 2 5,005 0 0
Carlyle Group Inc/The Common / Ordinary Stock 14316J108 1,256 45,053 SH   DFND 2 45,053 0 0
CarMax Inc Common / Ordinary Stock 143130102 249 2,789 SH   DFND 2 2,789 0 0
Carnival Corp Common / Ordinary Stock 143658300 216 13,209 SH   DFND 1,2 13,209 0 0
Carrier Global Corp Common / Ordinary Stock 14448C104 433 19,511 SH   DFND 2 19,511 0 0
Caterpillar Inc Common / Ordinary Stock 149123101 3,442 27,214 SH   DFND 1,2 27,214 0 0
Cboe Global Markets Inc Common / Ordinary Stock 12503M108 2,123 22,764 SH   DFND 2,3 22,764 0 0
CBRE Group Inc Common / Ordinary Stock 12504L109 1,819 40,226 SH   DFND 2 40,226 0 0
CDW Corp/DE Common / Ordinary Stock 12514G108 1,124 9,675 SH   DFND 2,3 9,675 0 0
Celanese Corp Common / Ordinary Stock 150870103 614 7,113 SH   DFND 2 7,113 0 0
Cemex SAB de CV American Depository Receipts ADR 151290889 256 89,108 SH   DFND 1,7,8 89,108 0 0
Centene Corp Common / Ordinary Stock 15135B101 747 11,767 SH   DFND 1,2 11,767 0 0
CenturyLink Inc Common / Ordinary Stock 156700106 459 45,803 SH   DFND 1,2 45,803 0 0
Cerner Corp Common / Ordinary Stock 156782104 1,354 19,758 SH   DFND 2 19,758 0 0
CF Industries Holdings Inc Common / Ordinary Stock 125269100 3,817 135,667 SH   DFND 2,3 135,667 0 0
CGI Inc Common / Ordinary Stock 12532H104 760 12,114 SH   DFND 2,3 12,114 0 0
Charles Schwab Corp/The Common / Ordinary Stock 808513105 1,430 42,394 SH   DFND 1,2,4 42,394 0 0
Charter Communications Inc Common / Ordinary Stock 16119P108 10,410 20,411 SH   DFND 1,2,3,4,5 20,411 0 0
Chegg Inc Common / Ordinary Stock 163092109 727 10,820 SH   DFND 2 10,820 0 0
Chevron Corp Common / Ordinary Stock 166764100 5,020 56,261 SH   DFND 1,2 56,261 0 0
Chipotle Mexican Grill Inc Common / Ordinary Stock 169656105 1,214 1,154 SH   DFND 1,2 1,154 0 0
Chubb Limited Com Common / Ordinary Stock H1467J104 2,480 19,594 SH   DFND 2,4 19,594 0 0
Church & Dwight Co Inc Common / Ordinary Stock 171340102 1,192 15,428 SH   DFND 2 15,428 0 0
Cia de Minas Buenaventura SAA American Depository Receipts ADR 204448104 4,572 500,293 SH   DFND 1,2,8 500,293 0 0
Cidara Therapeutics Inc Common / Ordinary Stock 171757107 323 87,782 SH   DFND 2 87,782 0 0
Cigna Corp Common / Ordinary Stock 125523100 6,062 32,309 SH   DFND 1,2,4 32,309 0 0
Cincinnati Financial Corp Common / Ordinary Stock 172062101 768 12,002 SH   DFND 2 12,002 0 0
Cintas Corp Common / Ordinary Stock 172908105 384 1,444 SH   DFND 2 1,444 0 0
Cisco Systems Inc Common / Ordinary Stock 17275R102 27,117 581,411 SH   DFND 1,2,3,5,7 581,411 0 0
Citigroup Inc Common / Ordinary Stock 172967424 21,313 417,087 SH   DFND 1,2 417,087 0 0
Citizens Financial Group Inc Common / Ordinary Stock 174610105 724 28,694 SH   DFND 2 28,694 0 0
Citrix Systems Inc Common / Ordinary Stock 177376100 1,165 7,880 SH   DFND 2,3 7,880 0 0
Clean Harbors Inc Common / Ordinary Stock 184496107 1,008 16,814 SH   DFND 2 16,814 0 0
Clorox Co/The Common / Ordinary Stock 189054109 1,644 7,498 SH   DFND 2 7,498 0 0
Cloudera Inc Common / Ordinary Stock 18914U100 2,504 196,874 SH   DFND 2 196,874 0 0
CME Group Inc Common / Ordinary Stock 12572Q105 4,004 24,634 SH   DFND 1,2,3,5 24,634 0 0
CMS Energy Corp Common / Ordinary Stock 125896100 286 4,905 SH   DFND 2 4,905 0 0
Coca-Cola Co/The Common / Ordinary Stock 191216100 19,062 426,635 SH   DFND 1,2,3,4,7 426,635 0 0
Cognex Corp Common / Ordinary Stock 192422103 2,127 35,620 SH   DFND 2,3 35,620 0 0
Cognizant Technology Solutions Corp Common / Ordinary Stock 192446102 6,167 108,544 SH   DFND 2,3 108,544 0 0
Coherent Inc Common / Ordinary Stock 192479103 1,857 14,179 SH   DFND 2,3 14,179 0 0
Colgate-Palmolive Co Common / Ordinary Stock 194162103 3,879 52,951 SH   DFND 1,2 52,951 0 0
Comcast Corp Common / Ordinary Stock 20030N101 14,288 366,553 SH   DFND 1,2,3,5 366,553 0 0
Comerica Inc Common / Ordinary Stock 200340107 1,249 32,796 SH   DFND 2 32,796 0 0
Conagra Brands Inc Common / Ordinary Stock 205887102 1,235 35,127 SH   DFND 2 35,127 0 0
ConocoPhillips Common / Ordinary Stock 20825C104 2,672 63,589 SH   DFND 1,2 63,589 0 0
Consolidated Edison Inc Common / Ordinary Stock 209115104 1,266 17,610 SH   DFND 1,2 17,610 0 0
Constellation Brands Inc Common / Ordinary Stock 21036P108 5,739 32,805 SH   DFND 1,2,4,7 32,805 0 0
Consumer Discretionary Select Sector SPDR Fund Exchange Traded Fund 81369Y407 3,612 28,289 SH   DFND 1,2,7 28,289 0 0
Consumer Staples Select Sector SPDR Fund Exchange Traded Fund 81369Y308 1,952 33,304 SH   DFND 1 33,304 0 0
Cooper Cos Inc/The Common / Ordinary Stock 216648402 239 843 SH   DFND 2 843 0 0
Copart Inc Common / Ordinary Stock 217204106 2,172 26,091 SH   DFND 2,4 26,091 0 0
Corning Inc Common / Ordinary Stock 219350105 1,339 51,713 SH   DFND 2,3 51,713 0 0
Corteva Inc Common / Ordinary Stock 22052L104 635 23,727 SH   DFND 1,2 23,727 0 0
Cortexyme Inc Common / Ordinary Stock 22053A107 231 5,000 SH   DFND 2 5,000 0 0
Costco Wholesale Corp Common / Ordinary Stock 22160K105 4,714 15,547 SH   DFND 2,5 15,547 0 0
Coupa Software Inc Common / Ordinary Stock 22266L106 999 3,608 SH   DFND 2,3 3,608 0 0
Crane Co Common / Ordinary Stock 224399105 1,077 18,117 SH   DFND 2 18,117 0 0
Credicorp Ltd Common / Ordinary Stock G2519Y108 0 12,659 SH   DFND 1,8 12,659 0 0
Credit Suisse Group AG American Depository Receipts ADR 225401108 320 31,100 SH   DFND 1 31,100 0 0
Crescent Point Energy Corp Common / Ordinary Stock 22576C101 48 30,217 SH   DFND 1 30,217 0 0
Cronos Group Inc Common / Ordinary Stock 22717L101 300 50,000 SH   DFND 2 50,000 0 0
Crowdstrike Holdings Inc Common / Ordinary Stock 22788C105 991 9,884 SH   DFND 2 9,884 0 0
Crown Castle International Corp Closed-end REIT 22822V101 1,831 10,943 SH   DFND 2 10,943 0 0
Crown Holdings Inc Common / Ordinary Stock 228368106 1,626 24,968 SH   DFND 4 24,968 0 0
CSX Corp Common / Ordinary Stock 126408103 1,020 14,627 SH   DFND 2,5 14,627 0 0
Cummins Inc Common / Ordinary Stock 231021106 1,070 6,181 SH   DFND 2 6,181 0 0
Curtiss-Wright Corp Common / Ordinary Stock 231561101 772 8,647 SH   DFND 2 8,647 0 0
CVS Health Corp Common / Ordinary Stock 126650100 4,740 72,970 SH   DFND 1,2,7 72,970 0 0
CytomX Therapeutics Inc Common / Ordinary Stock 23284F105 249 30,000 SH   DFND 2 30,000 0 0
Danaher Corp Common / Ordinary Stock 235851102 8,874 50,184 SH   DFND 1,2,3 50,184 0 0
Darden Restaurants Inc Common / Ordinary Stock 237194105 576 7,613 SH   DFND 2 7,613 0 0
Dasan Zhone Solutions Inc Common / Ordinary Stock 23305L206 178 20,000 SH   DFND 2 20,000 0 0
Deere & Co Common / Ordinary Stock 244199105 5,664 36,043 SH   DFND 2,3,7 36,043 0 0
Delta Air Lines Inc Common / Ordinary Stock 247361702 824 29,409 SH   DFND 1,2 29,409 0 0
Devon Energy Corp Common / Ordinary Stock 25179M103 168 14,865 SH   DFND 1,2 14,865 0 0
DexCom Inc Common / Ordinary Stock 252131107 3,983 9,825 SH   DFND 2 9,825 0 0
DHT Holdings Inc Shs New Common / Ordinary Stock Y2065G121 713 139,070 SH   DFND 2 139,070 0 0
Diamond S Shipping Inc Common / Ordinary Stock Y20676105 673 84,350 SH   DFND 2 84,350 0 0
Diamondback Energy Inc Common / Ordinary Stock 25278X109 581 13,905 SH   DFND 2,4 13,905 0 0
Digital Realty Trust Inc Closed-end REIT 253868103 653 4,598 SH   DFND 2 4,598 0 0
Discover Financial Services Common / Ordinary Stock 254709108 3,142 62,732 SH   DFND 2,3 62,732 0 0
Discovery Inc Common / Ordinary Stock 25470F104 618 29,298 SH   DFND 2 29,298 0 0
DocuSign Inc Common / Ordinary Stock 256163106 2,717 15,783 SH   DFND 2,3 15,783 0 0
Dollar General Corp Common / Ordinary Stock 256677105 821 4,314 SH   DFND 2 4,314 0 0
Dollar Tree Inc Common / Ordinary Stock 256746108 376 4,065 SH   DFND 2 4,065 0 0
Dominion Resources Inc/VA Common / Ordinary Stock 25746U109 1,184 14,585 SH   DFND 1,2 14,585 0 0
Domino's Pizza Inc Common / Ordinary Stock 25754A201 282 766 SH   DFND 2 766 0 0
Dorian LPG Ltd Common / Ordinary Stock Y2106R110 777 100,450 SH   DFND 2 100,450 0 0
Dover Corp Common / Ordinary Stock 260003108 238 2,467 SH   DFND 2 2,467 0 0
Dow Inc Common / Ordinary Stock 260557103 653 16,025 SH   DFND 1,2 16,025 0 0
DR Horton Inc Common / Ordinary Stock 23331A109 314 5,670 SH   DFND 2 5,670 0 0
Dropbox Inc Common / Ordinary Stock 26210C104 222 10,200 SH   DFND 1,2 10,200 0 0
DTE Energy Co Common / Ordinary Stock 233331107 920 8,564 SH   DFND 2 8,564 0 0
Duke Energy Corp Common / Ordinary Stock 26441C204 2,452 30,701 SH   DFND 1,2 30,701 0 0
Duke Realty Corp Closed-end REIT 264411505 764 21,600 SH   DFND 2 21,600 0 0
DuPont de Nemours Inc Common / Ordinary Stock 26614N102 844 15,891 SH   DFND 1,2 15,891 0 0
Durect Corp Common / Ordinary Stock 266605104 116 50,000 SH   DFND 2 50,000 0 0
DXC Technology Co Common / Ordinary Stock 23355L106 236 14,349 SH   DFND 2 14,349 0 0
Dynavax Technologies Corp Common / Ordinary Stock 268158201 443 50,000 SH   DFND 2 50,000 0 0
E TRADE Financial Corp Common / Ordinary Stock 269246401 300 6,037 SH   DFND 1,2 6,037 0 0
Eastman Chemical Co Common / Ordinary Stock 277432100 1,609 23,112 SH   DFND 2,4 23,112 0 0
eBay Inc Common / Ordinary Stock 278642103 2,555 48,726 SH   DFND 1,2,4 48,726 0 0
Ecolab Inc Common / Ordinary Stock 278865100 853 4,288 SH   DFND 1,2 4,288 0 0
Edison International Common / Ordinary Stock 281020107 1,464 26,973 SH   DFND 2 26,973 0 0
Edwards Lifesciences Corp Common / Ordinary Stock 28176E108 2,023 29,286 SH   DFND 1,2 29,286 0 0
eGain Corp Common / Ordinary Stock 28225C806 969 87,277 SH   DFND 2 87,277 0 0
Electronic Arts Inc Common / Ordinary Stock 285512109 9,244 70,006 SH   DFND 1,2,3,4 70,006 0 0
Eli Lilly and Co Common / Ordinary Stock 532457108 7,484 45,587 SH   DFND 1,2,4 45,587 0 0
Embraer SA American Depository Receipts ADR 29082A107 716 119,830 SH   DFND 1 119,830 0 0
EMCOR Group Inc Common / Ordinary Stock 29084Q100 919 13,909 SH   DFND 2 13,909 0 0
Emerson Electric Co Common / Ordinary Stock 291011104 1,223 19,725 SH   DFND 1,2 19,725 0 0
Enbridge Inc Common / Ordinary Stock 29250N105 699 23,079 SH   DFND 1,2 23,079 0 0
Energy Select Sector SPDR Fund Exchange Traded Fund 81369Y506 2,476 65,421 SH   DFND 1,2,7 65,421 0 0
Energy Transfer LP Master Limited Partnership 29273V100 186 26,233 SH   DFND 2 26,233 0 0
Enphase Energy Inc Common / Ordinary Stock 29355A107 603 12,695 SH   DFND 2 12,695 0 0
Entergy Corp Common / Ordinary Stock 29364G103 509 5,430 SH   DFND 1,2 5,430 0 0
EOG Resources Inc Common / Ordinary Stock 26875P101 1,483 29,278 SH   DFND 1,2,4 29,278 0 0
Equifax Inc Common / Ordinary Stock 294429105 874 5,085 SH   DFND 2 5,085 0 0
Equinix Inc Closed-end REIT 29444U700 1,139 1,623 SH   DFND 2,5 1,623 0 0
Equitable Holdings Inc Common / Ordinary Stock 29452E101 701 36,353 SH   DFND 2 36,353 0 0
Equity Residential Closed-end REIT 29476L107 821 13,969 SH   DFND 2 13,969 0 0
Esperion Therapeutics Inc Common / Ordinary Stock 29664W105 669 13,040 SH   DFND 2 13,040 0 0
Essential Utilities Inc Common / Ordinary Stock 29670G102 549 13,009 SH   DFND 2 13,009 0 0
Essex Property Trust Inc Closed-end REIT 297178105 256 1,121 SH   DFND 2 1,121 0 0
Estee Lauder Cos Inc/The Common / Ordinary Stock 518439104 4,953 26,255 SH   DFND 1,2 26,255 0 0
Eton Pharmaceuticals Inc Common / Ordinary Stock 29772L108 245 45,000 SH   DFND 2 45,000 0 0
Etsy Inc Common / Ordinary Stock 29786A106 1,186 11,173 SH   DFND 2 11,173 0 0
Euronav NV Common / Ordinary Stock B38564108 1,136 139,495 SH   DFND 2 139,495 0 0
Everbridge Inc Common / Ordinary Stock 29978A104 280 2,025 SH   DFND 2 2,025 0 0
Evergy Inc Common / Ordinary Stock 30034W106 230 3,886 SH   DFND 2 3,886 0 0
Eversource Energy Com Common / Ordinary Stock 30040W108 479 5,764 SH   DFND 2 5,764 0 0
Evofem Biosciences Inc Common / Ordinary Stock 30048L104 489 172,800 SH   DFND 2 172,800 0 0
Exact Sciences Corp Common / Ordinary Stock 30063P105 236 2,717 SH   DFND 2 2,717 0 0
Exelixis Inc Common / Ordinary Stock 30161Q104 474 20,000 SH   DFND 2 20,000 0 0
Exelon Corp Common / Ordinary Stock 30161N101 714 19,681 SH   DFND 1,2,5 19,681 0 0
Exicure Inc Common / Ordinary Stock 30205M101 122 50,000 SH   DFND 2 50,000 0 0
Expedia Group Inc Common / Ordinary Stock 30212P303 1,729 21,040 SH   DFND 1,2 21,040 0 0
Expeditors International of Washington Inc Common / Ordinary Stock 302130109 1,057 13,908 SH   DFND 2 13,908 0 0
Extra Space Storage Inc Closed-end REIT 30225T102 204 2,212 SH   DFND 2 2,212 0 0
Exxon Mobil Corp Common / Ordinary Stock 30231G102 7,227 161,610 SH   DFND 1,2 161,610 0 0
F5 Networks Inc Common / Ordinary Stock 315616102 750 5,378 SH   DFND 2 5,378 0 0
Facebook Inc Common / Ordinary Stock 30303M102 70,237 309,323 SH   DFND 1,2,3,4,5,7 309,323 0 0
FactSet Research Systems Inc Common / Ordinary Stock 303075105 3,879 11,811 SH   DFND 2,3 11,811 0 0
Fastenal Co Common / Ordinary Stock 311900104 1,080 25,224 SH   DFND 2 25,224 0 0
Fastly Inc Common / Ordinary Stock 31188V100 851 10,000 SH   DFND 2 10,000 0 0
FedEx Corp Common / Ordinary Stock 31428X106 3,515 25,074 SH   DFND 1,2,7 25,074 0 0
FibroGen Inc Common / Ordinary Stock 31572Q808 521 12,860 SH   DFND 2 12,860 0 0
Fidelity National Information Services Inc Common / Ordinary Stock 31620M106 11,420 85,173 SH   DFND 1,2,3,4 85,173 0 0
Fifth Third Bancorp Common / Ordinary Stock 316773100 235 12,200 SH   DFND 2 12,200 0 0
Financial Select Sector SPDR Fund Exchange Traded Fund 81369Y605 11,322 489,307 SH   DFND 1,2 489,307 0 0
First Republic Bank/CA Common / Ordinary Stock 33616C100 311 2,938 SH   DFND 2 2,938 0 0
First Solar Inc Common / Ordinary Stock 336433107 1,089 22,000 SH   DFND 2 22,000 0 0
FirstEnergy Corp Common / Ordinary Stock 337932107 368 9,505 SH   DFND 1,2 9,505 0 0
Fiserv Inc Common / Ordinary Stock 337738108 5,636 57,737 SH   DFND 2,3,5 57,737 0 0
FleetCor Technologies Inc Common / Ordinary Stock 339041105 4,809 19,119 SH   DFND 2,3,4 19,119 0 0
FLEX LNG Ltd Common / Ordinary Stock G35947202 636 137,733 SH   DFND 2 137,733 0 0
FLIR Systems Inc Common / Ordinary Stock 302445101 1,995 49,190 SH   DFND 2,3 49,190 0 0
FMC Corp Common / Ordinary Stock 302491303 221 2,219 SH   DFND 2 2,219 0 0
Fomento Economico Mexicano SAB de CV American Depository Receipts ADR 344419106 715 11,540 SH   DFND 1,7 11,540 0 0
Foot Locker Inc Common / Ordinary Stock 344849104 402 13,794 SH   DFND 1 13,794 0 0
Ford Motor Co Common / Ordinary Stock 345370860 2,995 492,681 SH   DFND 1,2 492,681 0 0
Fortinet Inc Common / Ordinary Stock 34959E109 1,965 14,321 SH   DFND 2,3 14,321 0 0
Fortis Inc/Canada Common / Ordinary Stock 349553107 648 17,098 SH   DFND 2 17,098 0 0
Fortive Corp Common / Ordinary Stock 34959J108 343 5,080 SH   DFND 2 5,080 0 0
Fortress Biotech Inc Common / Ordinary Stock 34960Q109 80 30,000 SH   DFND 2 30,000 0 0
Franklin Resources Inc Common / Ordinary Stock 354613101 690 32,942 SH   DFND 2 32,942 0 0
Freeport-McMoRan Inc Common / Ordinary Stock 35671D857 1,976 170,796 SH   DFND 1,2 170,796 0 0
G1 Therapeutics Inc Common / Ordinary Stock 3621LQ109 629 25,940 SH   DFND 2 25,940 0 0
Garmin Ltd Common / Ordinary Stock H2906T109 630 6,550 SH   DFND 1,2 6,550 0 0
General Dynamics Corp Common / Ordinary Stock 369550108 1,658 11,094 SH   DFND 2 11,094 0 0
General Electric Co Common / Ordinary Stock 369604103 4,242 621,204 SH   DFND 1,2,7 621,204 0 0
General Mills Inc Common / Ordinary Stock 370334104 2,520 40,888 SH   DFND 1,2 40,888 0 0
General Motors Co Common / Ordinary Stock 37045V100 2,074 81,993 SH   DFND 1,2,7 81,993 0 0
Gentex Corp Common / Ordinary Stock 371901109 1,974 76,619 SH   DFND 2 76,619 0 0
Genuine Parts Co Common / Ordinary Stock 372460105 214 2,472 SH   DFND 2 2,472 0 0
Gerdau SA American Depository Receipts ADR 373737105 412 139,233 SH   DFND 1 139,233 0 0
Gilead Sciences Inc Common / Ordinary Stock 375558103 3,439 44,707 SH   DFND 1,2,5 44,707 0 0
Global Blood Therapeutics Inc Common / Ordinary Stock 37890U108 315 5,000 SH   DFND 2 5,000 0 0
Global Payments Inc Common / Ordinary Stock 37940X102 7,153 42,174 SH   DFND 1,2,3 42,174 0 0
GoDaddy Inc Common / Ordinary Stock 380237107 645 8,797 SH   DFND 2,3 8,797 0 0
Golar LNG Ltd Common / Ordinary Stock G9456A100 849 117,300 SH   DFND 2 117,300 0 0
Goldman Sachs Group Inc/The Common / Ordinary Stock 38141G104 4,593 23,245 SH   DFND 1,2 23,245 0 0
Goodyear Tire & Rubber Co/The Common / Ordinary Stock 382550101 550 61,495 SH   DFND 1 61,495 0 0
GoPro Inc Common / Ordinary Stock 38268T103 57 11,993 SH   DFND 1 11,993 0 0
Groupon Inc Common / Ordinary Stock 399473107 20 15,066 SH   DFND 1 15,066 0 0
Grupo Financiero Galicia SA American Depository Receipts ADR 399909100 205 21,227 SH   DFND 1,4,8 21,227 0 0
Grupo Supervielle SA American Depository Receipts ADR 40054A108 288 130,933 SH   DFND 2 130,933 0 0
GSX Techedu Inc American Depository Receipts ADR 36257Y109 966 16,116 SH   DFND 2 16,116 0 0
Guidewire Software Inc Common / Ordinary Stock 40171V100 1,846 16,655 SH   DFND 2,3 16,655 0 0
GW Pharmaceuticals PLC American Depository Receipts ADR 36197T103 497 4,055 SH   DFND 2 4,055 0 0
Halliburton Co Common / Ordinary Stock 406216101 1,093 84,266 SH   DFND 1,2 84,266 0 0
Hanesbrands Inc Common / Ordinary Stock 410345102 443 39,249 SH   DFND 2 39,249 0 0
Hartford Financial Services Group Inc/The Common / Ordinary Stock 416515104 236 6,136 SH   DFND 2 6,136 0 0
Hasbro Inc Common / Ordinary Stock 418056107 407 5,435 SH   DFND 1,2 5,435 0 0
HCA Healthcare Inc Common / Ordinary Stock 40412C101 2,043 21,051 SH   DFND 1,2 21,051 0 0
Health Care Select Sector SPDR Fund Exchange Traded Fund 81369Y209 4,254 42,515 SH   DFND 1,2,7 42,515 0 0
HealthEquity Inc Common / Ordinary Stock 42226A107 1,880 32,044 SH   DFND 2,3 32,044 0 0
Healthpeak Properties Inc Closed-end REIT 42250P103 280 10,167 SH   DFND 1,2 10,167 0 0
Hecla Mining Co Common / Ordinary Stock 422704106 73 22,600 SH   DFND 2 22,600 0 0
Heron Therapeutics Inc Common / Ordinary Stock 427746102 303 20,600 SH   DFND 2 20,600 0 0
Hershey Co/The Common / Ordinary Stock 427866108 327 2,526 SH   DFND 2 2,526 0 0
Hess Corp Common / Ordinary Stock 42809H107 231 4,474 SH   DFND 2 4,474 0 0
Hewlett Packard Enterprise Co Common / Ordinary Stock 42824C109 936 96,215 SH   DFND 1,2,3 96,215 0 0
Hilton Worldwide Holdings Inc Common / Ordinary Stock 43300A203 931 12,677 SH   DFND 1,2 12,677 0 0
Hologic Inc Common / Ordinary Stock 436440101 2,458 43,125 SH   DFND 2,3 43,125 0 0
Home Depot Inc/The Common / Ordinary Stock 437076102 11,211 44,755 SH   DFND 1,2,4 44,755 0 0
Honeywell International Inc Common / Ordinary Stock 438516106 3,632 25,121 SH   DFND 2 25,121 0 0
Hormel Foods Corp Common / Ordinary Stock 440452100 5,933 122,920 SH   DFND 2,3 122,920 0 0
Host Hotels & Resorts Inc Closed-end REIT 44107P104 130 12,081 SH   DFND 2 12,081 0 0
HP Inc Common / Ordinary Stock 40434L105 5,267 302,208 SH   DFND 1,2,3 302,208 0 0
HubSpot Inc Common / Ordinary Stock 443573100 538 2,400 SH   DFND 2 2,400 0 0
Humana Inc Common / Ordinary Stock 444859102 3,504 9,037 SH   DFND 1,2 9,037 0 0
Huntington Bancshares Inc/OH Common / Ordinary Stock 446150104 1,326 146,784 SH   DFND 2,4 146,784 0 0
iClick Interactive Asia Group Ltd American Depository Receipts ADR 45113Y104 266 50,000 SH   DFND 2 50,000 0 0
IDEX Corp Common / Ordinary Stock 45167R104 204 1,292 SH   DFND 2 1,292 0 0
IDEXX Laboratories Inc Common / Ordinary Stock 45168D104 480 1,456 SH   DFND 2 1,456 0 0
IHS Markit Ltd Common / Ordinary Stock G47567105 516 6,836 SH   DFND 2 6,836 0 0
II-VI Inc Common / Ordinary Stock 902104108 284 6,035 SH   DFND 1,2 6,035 0 0
Illinois Tool Works Inc Common / Ordinary Stock 452308109 1,448 8,283 SH   DFND 2 8,283 0 0
Illumina Inc Common / Ordinary Stock 452327109 1,099 2,970 SH   DFND 2,5 2,970 0 0
Incyte Corp Common / Ordinary Stock 45337C102 638 6,145 SH   DFND 1,2 6,145 0 0
Industrial Select Sector SPDR Fund Exchange Traded Fund 81369Y704 698 10,166 SH   DFND 1,2,7 10,166 0 0
Ingredion Inc Common / Ordinary Stock 457187102 885 10,669 SH   DFND 2 10,669 0 0
Intel Corp Common / Ordinary Stock 458140100 34,798 581,625 SH   DFND 1,2,3,5 581,625 0 0
Intercept Pharmaceuticals Inc Common / Ordinary Stock 45845P108 479 10,000 SH   DFND 2 10,000 0 0
Intercontinental Exchange Inc Common / Ordinary Stock 45866F104 1,799 19,640 SH   DFND 2,4 19,640 0 0
International Business Machines Corp Common / Ordinary Stock 459200101 16,682 138,134 SH   DFND 1,2,3,7 138,134 0 0
International Flavors & Fragrances Inc Common / Ordinary Stock 459506101 1,990 16,255 SH   DFND 2 16,255 0 0
International Paper Co Common / Ordinary Stock 460146103 237 6,736 SH   DFND 2 6,736 0 0
International Seaways Inc Common / Ordinary Stock Y41053102 867 53,077 SH   DFND 2 53,077 0 0
Intra-Cellular Therapies Inc Common / Ordinary Stock 46116X101 770 30,000 SH   DFND 2 30,000 0 0
Intuit Inc Common / Ordinary Stock 461202103 12,046 40,672 SH   DFND 2,3,4,5 40,672 0 0
Intuitive Surgical Inc Common / Ordinary Stock 46120E602 6,871 12,059 SH   DFND 2,3,4,5 12,059 0 0
Invesco Ltd Common / Ordinary Stock G491BT108 117 10,948 SH   DFND 2 10,948 0 0
Invesco Nasdaq Internet ETF Exchange Traded Fund 46137V530 1,951 11,000 SH   DFND 5 11,000 0 0
Invesco QQQ Trust Series 1 Exchange Traded Fund 46090E103 43,182 174,404 SH   DFND 1,2,4,5 174,404 0 0
IPG Photonics Corp Common / Ordinary Stock 44980X109 1,330 8,294 SH   DFND 2 8,294 0 0
IQVIA Holdings Inc Common / Ordinary Stock 46266C105 431 3,043 SH   DFND 2 3,043 0 0
Iron Mountain Inc Closed-end REIT 46284V101 675 25,875 SH   DFND 2 25,875 0 0
iShares 1-3 Year Treasury Bond ETF Exchange Traded Fund 464287457 135,988 1,570,130 SH   DFND 4,9 1,570,130 0 0
iShares 20 Year Treasury Bond ETF Exchange Traded Fund 464287432 5,268 32,140 SH   DFND 1,9 32,140 0 0
iShares China Large-Cap ETF Exchange Traded Fund 464287184 16,220 408,577 SH   DFND 1,2,7 408,577 0 0
iShares Core S&P 500 ETF Exchange Traded Fund 464287200 3,213 10,375 SH   DFND 2,8,10 10,375 0 0
iShares Core U.S. Aggregate Bond ETF Exchange Traded Fund 464287226 3,667 31,025 SH   DFND 9 31,025 0 0
iShares Currency Hedged MSCI Eurozone ETF Exchange Traded Fund 46434V639 2,936 104,356 SH   DFND 4,10 104,356 0 0
iShares Currency Hedged MSCI Japan ETF Exchange Traded Fund 46434V886 803 26,156 SH   DFND 9 26,156 0 0
iShares Edge MSCI Min Vol Emerging Markets ETF Exchange Traded Fund 464286533 761 14,650 SH   DFND 2 14,650 0 0
iShares Emerging Markets Local Currency Bond ETF Exchange Traded Fund 464286517 1,359 33,336 SH   DFND 4 33,336 0 0
iShares Floating Rate Bond ETF Exchange Traded Fund 46429B655 26,429 522,431 SH   DFND 2,4,9 522,431 0 0
iShares Global Energy ETF Exchange Traded Fund 464287341 1,563 80,000 SH   DFND 5 80,000 0 0
iShares Global Industrials ETF Exchange Traded Fund 464288729 1,126 13,500 SH   DFND 5 13,500 0 0
iShares Global Infrastructure ETF Exchange Traded Fund 464288372 1,503 39,278 SH   DFND 4 39,278 0 0
iShares Global Tech ETF Exchange Traded Fund 464287291 1,413 6,000 SH   DFND 5 6,000 0 0
iShares Gold Trust Exchange Traded Fund 464285105 2,070 121,891 SH   DFND 4 121,891 0 0
iShares iBoxx USD Investment Grade Corporate Bond ETF Exchange Traded Fund 464287242 19,452 144,630 SH   DFND 9 144,630 0 0
Ishares Inc Msci Global Gold Miners Etf (Post Splt) Exchange Traded Fund 46434G855 489 16,201 SH   DFND 8 16,201 0 0
iShares JP Morgan USD Emerging Markets Bond ETF Exchange Traded Fund 464288281 963 8,821 SH   DFND 1,2,4 8,821 0 0
iShares Latin America 40 ETF Exchange Traded Fund 464287390 509 23,639 SH   DFND 4 23,639 0 0
iShares MSCI ACWI ETF Exchange Traded Fund 464288257 40,346 547,294 SH   DFND 1,4,7,10 547,294 0 0
iShares MSCI All Country Asia ex Japan ETF Exchange Traded Fund 464288182 6,055 87,550 SH   DFND 2,4,10 87,550 0 0
iShares MSCI All Country World Minimum Volatility ETF Exchange Traded Fund 464286525 1,571 17,940 SH   DFND 10 17,940 0 0
iShares MSCI Brazil Capped ETF Exchange Traded Fund 464286400 20,342 707,318 SH   DFND 1,2,4,7 707,318 0 0
iShares MSCI Canada ETF Exchange Traded Fund 464286509 885 34,221 SH   DFND 1 34,221 0 0
iShares MSCI China ETF Exchange Traded Fund 46429B671 3,408 52,073 SH   DFND 1,4,7 52,073 0 0
iShares MSCI EAFE ETF Exchange Traded Fund 464287465 6,056 99,498 SH   DFND 1 99,498 0 0
iShares MSCI Emerging Markets ETF Exchange Traded Fund 464287234 10,804 270,182 SH   DFND 1,2,7,10 270,182 0 0
iShares MSCI Eurozone ETF Exchange Traded Fund 464286608 4,419 121,160 SH   DFND 10 121,160 0 0
iShares MSCI Hong Kong ETF Exchange Traded Fund 464286871 481 22,517 SH   DFND 1 22,517 0 0
iShares MSCI Japan ETF Exchange Traded Fund 46434G822 5,729 104,318 SH   DFND 1,2,4,7,10 104,318 0 0
iShares MSCI Mexico Capped ETF Exchange Traded Fund 464286822 345 10,850 SH   DFND 1,7 10,850 0 0
iShares MSCI Singapore ETF Exchange Traded Fund 46434G780 449 23,926 SH   DFND 1 23,926 0 0
iShares MSCI South Korea Capped ETF Exchange Traded Fund 464286772 1,666 29,179 SH   DFND 1 29,179 0 0
iShares MSCI Taiwan ETF Exchange Traded Fund 46434G772 424 10,551 SH   DFND 1 10,551 0 0
iShares Nasdaq Biotechnology ETF Exchange Traded Fund 464287556 1,225 8,967 SH   DFND 1,5 8,967 0 0
iShares Preferred & Income Securities ETF Exchange Traded Fund 464288687 225 6,523 SH   DFND 4 6,523 0 0
iShares Russell 1000 Growth ETF Exchange Traded Fund 464287614 1,853 9,658 SH   DFND 4 9,658 0 0
iShares Russell 2000 ETF Exchange Traded Fund 464287655 13,909 97,150 SH   DFND 1,2 97,150 0 0
iShares S&P 500 Value ETF Exchange Traded Fund 464287408 1,593 14,727 SH   DFND 2,10 14,727 0 0
iShares Short Treasury Bond ETF Exchange Traded Fund 464288679 126,830 1,145,304 SH   DFND 4,9 1,145,304 0 0
iShares Silver Trust Exchange Traded Fund 46428Q109 234 13,785 SH   DFND 1,2 13,785 0 0
iShares TIPS Bond ETF Exchange Traded Fund 464287176 792 6,441 SH   DFND 2 6,441 0 0
iShares US Real Estate ETF Exchange Traded Fund 464287739 1,126 14,300 SH   DFND 4,9 14,300 0 0
iShares US Technology ETF Exchange Traded Fund 464287721 697 2,587 SH   DFND 2 2,587 0 0
Itau Unibanco Holding SA American Depository Receipts ADR 465562106 10,994 2,344,223 SH   DFND 1 2,344,223 0 0
Jack Henry & Associates Inc Common / Ordinary Stock 426281101 957 5,202 SH   DFND 2,3 5,202 0 0
Jacobs Engineering Group Inc Common / Ordinary Stock 469814107 602 7,110 SH   DFND 2 7,110 0 0
JB Hunt Transport Services Inc Common / Ordinary Stock 445658107 1,654 13,745 SH   DFND 2 13,745 0 0
JD.com Inc American Depository Receipts ADR 47215P106 1,726 28,684 SH   DFND 1,5,7 28,684 0 0
Jianpu Technology Inc American Depository Receipts ADR 47738D101 169 260,000 SH   DFND 2 260,000 0 0
JM Smucker Co/The Common / Ordinary Stock 832696405 578 5,467 SH   DFND 2 5,467 0 0
Johnson & Johnson Common / Ordinary Stock 478160104 10,728 76,291 SH   DFND 1,2,7 76,291 0 0
JOYY Inc ADR American Depository Receipts ADR 46591M109 456 5,150 SH   DFND 1,2,7 5,150 0 0
JPMorgan Chase & Co Common / Ordinary Stock 46625H100 13,408 142,556 SH   DFND 1,2,4,7 142,556 0 0
Jumia Technologies AG American Depository Receipts ADR 48138M105 137 25,000 SH   DFND 2 25,000 0 0
Juniper Networks Inc Common / Ordinary Stock 48203R104 701 30,698 SH   DFND 2 30,698 0 0
Kadmon Holdings Inc Common / Ordinary Stock 48283N106 426 83,290 SH   DFND 2 83,290 0 0
Kala Pharmaceuticals Inc Common / Ordinary Stock 483119103 8,386 797,910 SH   DFND 2 797,910 0 0
Kansas City Southern Common / Ordinary Stock 485170302 1,072 7,181 SH   DFND 2 7,181 0 0
Kellogg Co Common / Ordinary Stock 487836108 3,017 45,677 SH   DFND 1,2 45,677 0 0
KemPharm Inc Common / Ordinary Stock 488445107 114 400,000 SH   DFND 2 400,000 0 0
KeyCorp Common / Ordinary Stock 493267108 1,266 103,998 SH   DFND 2,4 103,998 0 0
Keysight Technologies Inc Common / Ordinary Stock 49338L103 3,581 35,540 SH   DFND 2,3 35,540 0 0
Kezar Life Sciences Inc Common / Ordinary Stock 49372L100 233 45,000 SH   DFND 2 45,000 0 0
Kimberly-Clark Corp Common / Ordinary Stock 494368103 2,356 16,671 SH   DFND 1,2 16,671 0 0
Kinder Morgan Inc Common / Ordinary Stock 49456B101 1,456 95,990 SH   DFND 1,2 95,990 0 0
Kinross Gold Corp Common / Ordinary Stock 496902404 452 62,636 SH   DFND 2 62,636 0 0
Kirkland Lake Gold Ltd Common / Ordinary Stock 49741E100 448 10,928 SH   DFND 2 10,928 0 0
KLA Corp Common / Ordinary Stock 482480100 3,373 17,344 SH   DFND 1,2,3 17,344 0 0
Kohl's Corp Common / Ordinary Stock 500255104 1,351 65,077 SH   DFND 1,2 65,077 0 0
Kraft Heinz Co/The Common / Ordinary Stock 500754106 2,389 74,930 SH   DFND 1,2,5 74,930 0 0
Kroger Co/The Common / Ordinary Stock 501044101 2,313 68,339 SH   DFND 1,2 68,339 0 0
L Brands Inc Common / Ordinary Stock 501797104 847 56,602 SH   DFND 1,2 56,602 0 0
L3Harris Technologies Inc Common / Ordinary Stock 502431109 1,391 8,202 SH   DFND 2 8,202 0 0
Laboratory Corp of America Holdings Common / Ordinary Stock 50540R409 276 1,665 SH   DFND 2 1,665 0 0
Lam Research Corp Common / Ordinary Stock 512807108 6,577 20,334 SH   DFND 1,2,3,5 20,334 0 0
Las Vegas Sands Corp Common / Ordinary Stock 517834107 1,932 42,431 SH   DFND 1,2,4 42,431 0 0
Leidos Holdings Inc Common / Ordinary Stock 525327102 4,584 48,946 SH   DFND 2,3,4 48,946 0 0
Lennar Corp Common / Ordinary Stock 526057104 289 4,706 SH   DFND 2 4,706 0 0
Liberty Broadband Corp Common / Ordinary Stock 530307305 671 5,415 SH   DFND 2,3 5,415 0 0
Lipocine Inc Common / Ordinary Stock 53630X104 252 200,000 SH   DFND 2 200,000 0 0
Liquidia Technologies Inc Common / Ordinary Stock 53635D202 926 110,000 SH   DFND 2 110,000 0 0
Lithium Americas Corp Common / Ordinary Stock 53680Q207 205 40,000 SH   DFND 2 40,000 0 0
Lockheed Martin Corp Common / Ordinary Stock 539830109 2,573 7,052 SH   DFND 1,2 7,052 0 0
Logitech International SA Common / Ordinary Stock H50430232 296 4,550 SH   DFND 2 4,550 0 0
LogMeIn Inc Common / Ordinary Stock 54142L109 1,271 15,000 SH   DFND 2 15,000 0 0
Loma Negra Cia Industrial Argentina SA American Depository Shares - ADS 54150E104 190 44,726 SH   DFND 2 44,726 0 0
Lowe's Cos Inc Common / Ordinary Stock 548661107 4,253 31,483 SH   DFND 1,2 31,483 0 0
Lululemon Athletica Inc Common / Ordinary Stock 550021109 424 1,361 SH   DFND 2 1,361 0 0
Lyft Inc Common / Ordinary Stock 55087P104 282 8,560 SH   DFND 1 8,560 0 0
M&T Bank Corp Common / Ordinary Stock 55261F104 228 2,199 SH   DFND 2 2,199 0 0
Macerich Co/The Closed-end REIT 554382101 324 36,186 SH   DFND 1,2 36,186 0 0
Macy's Inc Common / Ordinary Stock 55616P104 170 24,719 SH   DFND 1 24,719 0 0
Magna International Inc Common / Ordinary Stock 559222401 1,017 22,932 SH   DFND 2 22,932 0 0
ManpowerGroup Inc Common / Ordinary Stock 56418H100 586 8,538 SH   DFND 2 8,538 0 0
Manulife Financial Corp Common / Ordinary Stock 56501R106 326 24,100 SH   DFND 2 24,100 0 0
Marathon Oil Corp Common / Ordinary Stock 565849106 1,162 189,994 SH   DFND 1,2 189,994 0 0
Marathon Petroleum Corp Common / Ordinary Stock 56585A102 479 12,823 SH   DFND 1,2 12,823 0 0
Marker Therapeutics Inc Common / Ordinary Stock 57055L107 118 57,042 SH   DFND 2 57,042 0 0
MarketAxess Holdings Inc Common / Ordinary Stock 57060D108 3,701 7,390 SH   DFND 2,3 7,390 0 0
Marriott International Inc/MD Common / Ordinary Stock 571903202 592 6,913 SH   DFND 1,2,5 6,913 0 0
Marsh & McLennan Cos Inc Common / Ordinary Stock 571748102 1,688 15,722 SH   DFND 2 15,722 0 0
Martin Marietta Materials Inc Common / Ordinary Stock 573284106 1,402 6,788 SH   DFND 2 6,788 0 0
Marvell Technology Group Ltd Common / Ordinary Stock G5876H105 2,644 75,433 SH   DFND 2,3 75,433 0 0
Masco Corp Common / Ordinary Stock 574599106 226 4,520 SH   DFND 2 4,520 0 0
Mastercard Inc Common / Ordinary Stock 57636Q104 29,894 101,097 SH   DFND 1,2,3,4 101,097 0 0
Match Group Inc Common / Ordinary Stock 44919P508 1,289 3,987 SH   DFND 2,3 3,987 0 0
Match Group Inc/old Common / Ordinary Stock 57665R106 914 8,541 SH   DFND 4 8,541 0 0
Materials Select Sector SPDR Fund Exchange Traded Fund 81369Y100 435 7,720 SH   DFND 1 7,720 0 0
Mattel Inc Common / Ordinary Stock 577081102 463 47,921 SH   DFND 1 47,921 0 0
Maxim Integrated Products Inc Common / Ordinary Stock 57772K101 1,104 18,223 SH   DFND 2,3 18,223 0 0
McCormick & Co Inc/MD Common / Ordinary Stock 579780206 380 2,120 SH   DFND 2 2,120 0 0
McDonald's Corp Common / Ordinary Stock 580135101 10,648 57,725 SH   DFND 1,2,4 57,725 0 0
McKesson Corp Common / Ordinary Stock 58155Q103 425 2,774 SH   DFND 2 2,774 0 0
Medallia Inc Common / Ordinary Stock 584021109 757 30,000 SH   DFND 2 30,000 0 0
Menlo Therapeutics Inc Common / Ordinary Stock 586858102 1,120 647,648 SH   DFND 2 647,648 0 0
MercadoLibre Inc Common / Ordinary Stock 58733R102 1,162 1,179 SH   DFND 1,2,4,8 1,179 0 0
Merck & Co Inc Common / Ordinary Stock 58933Y105 9,413 121,735 SH   DFND 1,2 121,735 0 0
MetLife Inc Common / Ordinary Stock 59156R108 2,831 77,546 SH   DFND 1,2 77,546 0 0
Mettler-Toledo International Inc Common / Ordinary Stock 592688105 780 969 SH   DFND 2 969 0 0
MGM Resorts International Common / Ordinary Stock 552953101 665 39,637 SH   DFND 1,2 39,637 0 0
Microchip Technology Inc Common / Ordinary Stock 595017104 1,721 16,346 SH   DFND 2,3 16,346 0 0
Micron Technology Inc Common / Ordinary Stock 595112103 9,192 178,422 SH   DFND 1,2,3,5,7 178,422 0 0
Microsoft Corp Common / Ordinary Stock 594918104 170,091 835,789 SH   DFND 1,2,3,4,5,7 835,789 0 0
Mid-America Apartment Communities Inc Closed-end REIT 59522J103 224 1,960 SH   DFND 2 1,960 0 0
MKS Instruments Inc Common / Ordinary Stock 55306N104 1,124 9,932 SH   DFND 2 9,932 0 0
Momo Inc American Depository Receipts ADR 60879B107 633 36,243 SH   DFND 1,2,7 36,243 0 0
Mondelez International Inc Common / Ordinary Stock 609207105 3,238 63,331 SH   DFND 1,2,5 63,331 0 0
Monster Beverage Corp Common / Ordinary Stock 61174X109 2,454 35,414 SH   DFND 2,5 35,414 0 0
Moody's Corp Common / Ordinary Stock 615369105 3,719 13,539 SH   DFND 1,2 13,539 0 0
Morgan Stanley Common / Ordinary Stock 617446448 8,037 166,418 SH   DFND 1,2,4 166,418 0 0
Motorola Solutions Inc Common / Ordinary Stock 620076307 1,619 11,560 SH   DFND 2,3 11,560 0 0
MSCI Inc Common / Ordinary Stock 55354G100 556 1,667 SH   DFND 2 1,667 0 0
Myovant Sciences Ltd Common / Ordinary Stock G637AM102 412 20,000 SH   DFND 2 20,000 0 0
Nasdaq Inc Common / Ordinary Stock 631103108 235 1,968 SH   DFND 2 1,968 0 0
Navigator Holdings Ltd Common / Ordinary Stock Y62132108 88 13,801 SH   DFND 2 13,801 0 0
Navios Maritime Containers LP Composite Units Y62151108 18 23,240 SH   DFND 2 23,240 0 0
Navios Maritime Partners LP Common / Ordinary Stock Y62267409 530 54,633 SH   DFND 2 54,633 0 0
Netflix Inc Common / Ordinary Stock 64110L106 22,232 48,858 SH   DFND 1,2,3,4,5,7 48,858 0 0
Neurocrine Biosciences Inc Common / Ordinary Stock 64125C109 610 5,000 SH   DFND 2 5,000 0 0
New Relic Inc Common / Ordinary Stock 64829B100 1,205 17,500 SH   DFND 2 17,500 0 0
New York Times Co/The Common / Ordinary Stock 650111107 624 14,854 SH   DFND 2 14,854 0 0
Newmont Corp Common / Ordinary Stock 651639106 2,088 33,828 SH   DFND 1,2 33,828 0 0
NextEra Energy Inc Common / Ordinary Stock 65339F101 7,670 31,938 SH   DFND 2,4 31,938 0 0
NIKE Inc Common / Ordinary Stock 654106103 8,387 85,540 SH   DFND 1,2,3,7 85,540 0 0
Nordson Corp Common / Ordinary Stock 655663102 2,561 13,502 SH   DFND 2,3 13,502 0 0
Norfolk Southern Corp Common / Ordinary Stock 655844108 3,827 21,802 SH   DFND 2,4 21,802 0 0
Northern Trust Corp Common / Ordinary Stock 665859104 282 3,566 SH   DFND 2 3,566 0 0
Northrop Grumman Corp Common / Ordinary Stock 666807102 4,314 14,035 SH   DFND 2,4 14,035 0 0
NortonLifeLock Inc Common / Ordinary Stock 668771108 1,489 75,096 SH   DFND 2 75,096 0 0
NuCana PLC American Depository Receipts ADR 67022C106 703 130,000 SH   DFND 2 130,000 0 0
Nucor Corp Common / Ordinary Stock 670346105 213 5,161 SH   DFND 2 5,161 0 0
NVIDIA Corp Common / Ordinary Stock 67066G104 36,202 95,291 SH   DFND 1,2,3,4,5,7 95,291 0 0
Occidental Petroleum Corp Common / Ordinary Stock 674599105 1,836 100,367 SH   DFND 1,2 100,367 0 0
Okta Inc Common / Ordinary Stock 679295105 1,247 6,230 SH   DFND 2,3 6,230 0 0
Old Dominion Freight Line Inc Common / Ordinary Stock 679580100 1,112 6,558 SH   DFND 2 6,558 0 0
Omega Healthcare Investors Inc Closed-end REIT 681936100 479 16,138 SH   DFND 2 16,138 0 0
Omnicom Group Inc Common / Ordinary Stock 681919106 200 3,672 SH   DFND 2 3,672 0 0
Oncolytics Biotech Inc Common / Ordinary Stock 682310875 56 30,000 SH   DFND 2 30,000 0 0
ONEOK Inc Common / Ordinary Stock 682680103 235 7,093 SH   DFND 2 7,093 0 0
Open Text Corp Common / Ordinary Stock 683715106 1,340 31,671 SH   DFND 2 31,671 0 0
Oracle Corp Common / Ordinary Stock 68389X105 12,005 217,218 SH   DFND 1,2,3 217,218 0 0
O'Reilly Automotive Inc Common / Ordinary Stock 67103H107 5,095 12,085 SH   DFND 2,4,5 12,085 0 0
Ormat Technologies Inc Common / Ordinary Stock 686688102 1,000 15,757 SH   DFND 2 15,757 0 0
Otis Worldwide Corp Common / Ordinary Stock 68902V107 554 9,754 SH   DFND 2 9,754 0 0
PACCAR Inc Common / Ordinary Stock 693718108 1,094 14,622 SH   DFND 2 14,622 0 0
Packaging Corp of America Common / Ordinary Stock 695156109 644 6,453 SH   DFND 2 6,453 0 0
Palo Alto Networks Inc Common / Ordinary Stock 697435105 2,581 11,240 SH   DFND 1,2,3 11,240 0 0
Paratek Pharmaceuticals Inc Common / Ordinary Stock 699374302 548 105,000 SH   DFND 2 105,000 0 0
Parker Hannifin Corp Common / Ordinary Stock 701094104 573 3,131 SH   DFND 2 3,131 0 0
Paychex Inc Common / Ordinary Stock 704326107 1,652 21,819 SH   DFND 2,3 21,819 0 0
Paycom Software Inc Common / Ordinary Stock 70432V102 1,041 3,363 SH   DFND 2,3 3,363 0 0
PayPal Holdings Inc Common / Ordinary Stock 70450Y103 31,480 180,686 SH   DFND 1,2,3,4,5 180,686 0 0
Pembina Pipeline Corp Common / Ordinary Stock 706327103 710 28,493 SH   DFND 2 28,493 0 0
Penumbra Inc Common / Ordinary Stock 70975L107 1,131 6,327 SH   DFND 2 6,327 0 0
PepsiCo Inc Common / Ordinary Stock 713448108 6,901 52,181 SH   DFND 1,2,5 52,181 0 0
PetroChina Co Ltd American Depository Receipts ADR 71646E100 274 8,308 SH   DFND 7 8,308 0 0
Petroleo Brasileiro SA American Depository Receipts ADR 71654V408 4,417 534,161 SH   DFND 1,2,4,7,8 534,161 0 0
Pfizer Inc Common / Ordinary Stock 717081103 11,006 336,604 SH   DFND 1,2 336,604 0 0
Philip Morris International Inc Common / Ordinary Stock 718172109 4,519 64,506 SH   DFND 1,2,3 64,506 0 0
Phillips 66 Common / Ordinary Stock 718546104 1,752 24,373 SH   DFND 1,2 24,373 0 0
Pioneer Natural Resources Co Common / Ordinary Stock 723787107 1,494 15,294 SH   DFND 2,4 15,294 0 0
PNC Financial Services Group Inc/The Common / Ordinary Stock 693475105 842 8,011 SH   DFND 1,2 8,011 0 0
Portland General Electric Co Common / Ordinary Stock 736508847 860 20,583 SH   DFND 2 20,583 0 0
PPG Industries Inc Common / Ordinary Stock 693506107 428 4,042 SH   DFND 2 4,042 0 0
PPL Corp Common / Ordinary Stock 69351T106 564 21,842 SH   DFND 1,2 21,842 0 0
Precision Drilling Corp Common / Ordinary Stock 74022D308 37 50,000 SH   DFND 2 50,000 0 0
Premier Inc Common / Ordinary Stock 74051N102 1,200 35,009 SH   DFND 2 35,009 0 0
Procter & Gamble Co/The Common / Ordinary Stock 742718109 16,443 137,524 SH   DFND 1,2,3 137,524 0 0
Progressive Corp/The Common / Ordinary Stock 743315103 2,401 29,982 SH   DFND 2,4 29,982 0 0
Prologis Inc Closed-end REIT 74340W103 6,232 66,780 SH   DFND 2,4 66,780 0 0
Proofpoint Inc Common / Ordinary Stock 743424103 761 6,855 SH   DFND 2 6,855 0 0
ProShares S&P 500 Dividend Aristocrats ETF Exchange Traded Fund 74348A467 276 4,100 SH   DFND 2 4,100 0 0
ProShares UltraPro QQQ Exchange Traded Fund 74347X831 233 2,387 SH   DFND 2 2,387 0 0
Prudential Financial Inc Common / Ordinary Stock 744320102 412 6,769 SH   DFND 2 6,769 0 0
PTC Inc Common / Ordinary Stock 69370C100 492 6,328 SH   DFND 4 6,328 0 0
Public Service Enterprise Group Inc Common / Ordinary Stock 744573106 772 15,716 SH   DFND 1,2 15,716 0 0
Public Storage Closed-end REIT 74460D109 494 2,576 SH   DFND 2 2,576 0 0
Qorvo Inc Common / Ordinary Stock 74736K101 217 1,967 SH   DFND 2 1,967 0 0
Qualcomm Inc Common / Ordinary Stock 747525103 12,305 134,914 SH   DFND 1,2,3,5 134,914 0 0
Qualys Inc Common / Ordinary Stock 74758T303 604 5,808 SH   DFND 2 5,808 0 0
Quanta Services Inc Common / Ordinary Stock 74762E102 1,171 29,859 SH   DFND 2 29,859 0 0
Quest Diagnostics Inc Common / Ordinary Stock 74834L100 1,659 14,561 SH   DFND 2,4 14,561 0 0
Rapid7 Inc Common / Ordinary Stock 753422104 204 4,000 SH   DFND 2 4,000 0 0
Raytheon Technologies Corp Common / Ordinary Stock 75513E101 6,328 102,708 SH   DFND 2 102,708 0 0
Realty Income Corp Closed-end REIT 756109104 952 16,009 SH   DFND 2 16,009 0 0
Regency Centers Corp Closed-end REIT 758849103 694 15,125 SH   DFND 2 15,125 0 0
Regeneron Pharmaceuticals Inc Common / Ordinary Stock 75886F107 2,391 3,834 SH   DFND 2,5 3,834 0 0
Regions Financial Corp Common / Ordinary Stock 7591EP100 1,273 114,490 SH   DFND 2 114,490 0 0
RenaissanceRe Holdings Ltd Common / Ordinary Stock G7496G103 426 2,492 SH   DFND 2 2,492 0 0
Republic Services Inc Common / Ordinary Stock 760759100 684 8,339 SH   DFND 2 8,339 0 0
ResMed Inc Common / Ordinary Stock 761152107 475 2,478 SH   DFND 2 2,478 0 0
Retrophin Inc Common / Ordinary Stock 761299106 204 10,000 SH   DFND 2 10,000 0 0
RingCentral Inc Common / Ordinary Stock 76680R206 1,273 4,469 SH   DFND 2,3 4,469 0 0
Ritchie Bros Auctioneers Inc Common / Ordinary Stock 767744105 405 9,930 SH   DFND 2 9,930 0 0
Robert Half International Inc Common / Ordinary Stock 770323103 531 10,064 SH   DFND 2 10,064 0 0
Rockwell Automation Inc Common / Ordinary Stock 773903109 3,266 15,337 SH   DFND 2,3 15,337 0 0
Rockwell Medical Inc Common / Ordinary Stock 774374102 234 120,000 SH   DFND 2 120,000 0 0
Rogers Communications Inc Common / Ordinary Stock 775109200 712 17,796 SH   DFND 1,2,3 17,796 0 0
Roku Inc Common / Ordinary Stock 77543R102 251 2,157 SH   DFND 1 2,157 0 0
Roper Technologies Inc Common / Ordinary Stock 776696106 3,300 8,502 SH   DFND 2,3 8,502 0 0
Ross Stores Inc Common / Ordinary Stock 778296103 3,842 45,080 SH   DFND 2,4,5 45,080 0 0
Royal Dutch Shell PLC American Depository Receipts ADR 780259206 207 6,356 SH   DFND 1 6,356 0 0
S&P Global Inc Common / Ordinary Stock 78409V104 4,550 13,812 SH   DFND 2 13,812 0 0
salesforce.com Inc Common / Ordinary Stock 79466L302 19,979 106,656 SH   DFND 1,2,3,4,7 106,656 0 0
SandRidge Permian Trust Master Limited Partnership 80007A102 6 15,000 SH   DFND 2 15,000 0 0
Sarepta Therapeutics Inc Common / Ordinary Stock 803607100 721 4,500 SH   DFND 2 4,500 0 0
SBA Communications Corp Closed-end REIT 78410G104 569 1,913 SH   DFND 2 1,913 0 0
Schlumberger Ltd Common / Ordinary Stock 806857108 1,356 73,757 SH   DFND 1,2 73,757 0 0
Scorpio Tankers Inc Common / Ordinary Stock Y7542C130 472 36,890 SH   DFND 2 36,890 0 0
SCYNEXIS Inc Common / Ordinary Stock 811292101 638 850,000 SH   DFND 2 850,000 0 0
Selecta Biosciences Inc Common / Ordinary Stock 816212104 1,537 541,203 SH   DFND 2 541,203 0 0
Sempra Energy Common / Ordinary Stock 816851109 595 5,079 SH   DFND 1,2 5,079 0 0
ServiceNow Inc Common / Ordinary Stock 81762P102 9,792 24,176 SH   DFND 1,2,3 24,176 0 0
Sherwin-Williams Co/The Common / Ordinary Stock 824348106 800 1,385 SH   DFND 2 1,385 0 0
Shopify Inc Common / Ordinary Stock 82509L107 5,618 5,933 SH   DFND 1,2,3 5,933 0 0
Simon Property Group Inc Closed-end REIT 828806109 610 8,933 SH   DFND 1,2 8,933 0 0
Skyworks Solutions Inc Common / Ordinary Stock 83088M102 1,468 11,483 SH   DFND 2,3 11,483 0 0
SmileDirectClub Inc Common / Ordinary Stock 83192H106 189 24,000 SH   DFND 2 24,000 0 0
Snap Inc Common / Ordinary Stock 83304A106 1,037 44,178 SH   DFND 2,3 44,178 0 0
Sociedad Quimica y Minera de Chile SA American Depository Receipts ADR 833635105 671 25,741 SH   DFND 1,2,8 25,741 0 0
SolarEdge Technologies Inc Common / Ordinary Stock 83417M104 1,040 7,500 SH   DFND 2 7,500 0 0
Soleno Therapeutics Inc Common / Ordinary Stock 834203200 111 50,000 SH   DFND 2 50,000 0 0
Sony Corp American Depository Receipts ADR 835699307 1,209 17,500 SH   DFND 2 17,500 0 0
Sorrento Therapeutics Inc Common / Ordinary Stock 83587F202 125 20,000 SH   DFND 2 20,000 0 0
Southern Co/The Common / Ordinary Stock 842587107 3,536 68,205 SH   DFND 1,2 68,205 0 0
Southern Copper Corp Common / Ordinary Stock 84265V105 680 17,121 SH   DFND 8 17,121 0 0
Southwest Airlines Co Common / Ordinary Stock 844741108 319 9,342 SH   DFND 1,2 9,342 0 0
SPDR Bloomberg Barclays 1-3 Month T-Bill ETF Exchange Traded Fund 78468R663 14,748 161,135 SH   DFND 4,9 161,135 0 0
SPDR Dow Jones Industrial Average ETF Trust Exchange Traded Fund 78467X109 2,904 11,264 SH   DFND 1,2,7 11,264 0 0
SPDR Euro STOXX 50 ETF Exchange Traded Fund 78463X202 4,621 130,076 SH   DFND 1,9 130,076 0 0
SPDR Gold Shares Exchange Traded Fund 78463V107 13,046 77,950 SH   DFND 1,2 77,950 0 0
SPDR S&P 500 ETF Trust Exchange Traded Fund 78462F103 72,948 236,570 SH   DFND 1,2,7 236,570 0 0
SPDR S&P Biotech ETF Exchange Traded Fund 78464A870 201 1,801 SH   DFND 1 1,801 0 0
SPDR S&P Oil & Gas Exploration & Production ETF Exchange Traded Fund 78468R556 1,511 28,971 SH   DFND 1,2 28,971 0 0
Spectrum Pharmaceuticals Inc Common / Ordinary Stock 84763A108 67 20,000 SH   DFND 2 20,000 0 0
Splunk Inc Common / Ordinary Stock 848637104 3,055 15,377 SH   DFND 1,2,3 15,377 0 0
Square Inc Common / Ordinary Stock 852234103 5,838 55,633 SH   DFND 1,2,3 55,633 0 0
SS&C Technologies Holdings Inc Common / Ordinary Stock 78467J100 1,645 29,138 SH   DFND 2,3 29,138 0 0
Stanley Black & Decker Inc Common / Ordinary Stock 854502101 1,349 9,684 SH   DFND 2,4 9,684 0 0
Star Bulk Carriers Corp Common / Ordinary Stock Y8162K204 378 57,386 SH   DFND 2 57,386 0 0
Starbucks Corp Common / Ordinary Stock 855244109 5,149 69,975 SH   DFND 1,2,5,7 69,975 0 0
State Street Corp Common / Ordinary Stock 857477103 1,114 17,530 SH   DFND 2 17,530 0 0
Steel Dynamics Inc Common / Ordinary Stock 858119100 409 15,708 SH   DFND 2 15,708 0 0
Stryker Corp Common / Ordinary Stock 863667101 3,039 16,867 SH   DFND 2,3 16,867 0 0
Sun Life Financial Inc Common / Ordinary Stock 866796105 398 10,892 SH   DFND 2 10,892 0 0
SVB Financial Group Common / Ordinary Stock 78486Q101 1,394 6,471 SH   DFND 2,4 6,471 0 0
Synchrony Financial Common / Ordinary Stock 87165B103 1,594 71,972 SH   DFND 1,2 71,972 0 0
Synopsys Inc Common / Ordinary Stock 871607107 1,988 10,199 SH   DFND 2,3 10,199 0 0
Sysco Corp Common / Ordinary Stock 871829107 1,383 25,303 SH   DFND 1,2 25,303 0 0
T Rowe Price Group Inc Common / Ordinary Stock 74144T108 1,199 9,714 SH   DFND 2 9,714 0 0
Taiwan Semiconductor Manufacturing Co Ltd American Depository Receipts ADR 874039100 5,517 97,194 SH   DFND 1,2,4 97,194 0 0
Take-Two Interactive Software Inc Common / Ordinary Stock 874054109 2,723 19,517 SH   DFND 1,2,3 19,517 0 0
TAL Education Group American Depository Receipts ADR 874080104 888 12,995 SH   DFND 1,2,7 12,995 0 0
Talend SA American Depository Receipts ADR 874224207 963 27,800 SH   DFND 2 27,800 0 0
Tapestry Inc Common / Ordinary Stock 876030107 629 47,389 SH   DFND 1,2 47,389 0 0
Target Corp Common / Ordinary Stock 87612E106 4,872 40,628 SH   DFND 1,2 40,628 0 0
TC Energy Corp Common / Ordinary Stock 87807B107 695 16,322 SH   DFND 1,2 16,322 0 0
Technology Select Sector SPDR Fund Exchange Traded Fund 81369Y803 4,630 44,319 SH   DFND 1,2,7 44,319 0 0
Teekay Corp Common / Ordinary Stock Y8564W103 613 255,591 SH   DFND 2 255,591 0 0
Teekay LNG Partners LP Master Limited Partnership Y8564M105 822 70,515 SH   DFND 2 70,515 0 0
Teekay Tankers Ltd Common / Ordinary Stock Y8565N300 694 54,160 SH   DFND 2 54,160 0 0
Teladoc Health Inc Common / Ordinary Stock 87918A105 1,338 7,013 SH   DFND 2 7,013 0 0
Teleflex Inc Common / Ordinary Stock 879369106 289 796 SH   DFND 2 796 0 0
Tellurian Inc Common / Ordinary Stock 87968A104 38 33,369 SH   DFND 2 33,369 0 0
TELUS Corp Common / Ordinary Stock 87971M103 843 50,438 SH   DFND 2 50,438 0 0
Teradyne Inc Common / Ordinary Stock 880770102 1,310 15,503 SH   DFND 2 15,503 0 0
Tesla Inc Common / Ordinary Stock 88160R101 16,296 15,092 SH   DFND 1,2,5 15,092 0 0
Teva Pharmaceutical Industries Ltd American Depository Receipts ADR 881624209 2,687 217,969 SH   DFND 1 217,969 0 0
Texas Instruments Inc Common / Ordinary Stock 882508104 12,052 94,924 SH   DFND 1,2,3,4,5 94,924 0 0
TherapeuticsMD Inc Common / Ordinary Stock 88338N107 175 140,000 SH   DFND 2 140,000 0 0
Thermo Fisher Scientific Inc Common / Ordinary Stock 883556102 8,208 22,655 SH   DFND 1,2,3,4 22,655 0 0
Tiffany & Co Common / Ordinary Stock 886547108 228 1,871 SH   DFND 2 1,871 0 0
TJX Cos Inc/The Common / Ordinary Stock 872540109 1,274 25,209 SH   DFND 2 25,209 0 0
T-Mobile US Inc American Rights 872590112 4 28,336 SH   DFND 2,3 28,336 0 0
T-Mobile US Inc Common / Ordinary Stock 872590104 2,975 28,570 SH   DFND 1,2,3 28,570 0 0
Tractor Supply Co Common / Ordinary Stock 892356106 6,437 48,848 SH   DFND 2,3 48,848 0 0
Trade Desk Inc/The Common / Ordinary Stock 88339J105 2,203 5,420 SH   DFND 2,3 5,420 0 0
TransDigm Group Inc Common / Ordinary Stock 893641100 381 862 SH   DFND 2 862 0 0
Travelers Cos Inc/The Common / Ordinary Stock 89417E109 587 5,151 SH   DFND 1,2 5,151 0 0
Trevena Inc Common / Ordinary Stock 89532E109 675 450,000 SH   DFND 2 450,000 0 0
Trevi Therapeutics Inc Common / Ordinary Stock 89532M101 460 70,000 SH   DFND 2 70,000 0 0
Trex Co Inc Common / Ordinary Stock 89531P105 1,362 10,477 SH   DFND 2 10,477 0 0
Trillium Therapeutics Inc Common / Ordinary Stock 89620X506 210 25,984 SH   DFND 2 25,984 0 0
Trimble Inc Common / Ordinary Stock 896239100 2,119 49,064 SH   DFND 2,3 49,064 0 0
Trip Com Grp Ltd Spon Ads Each Rep 0.125 ORD SHS American Depository Receipts ADR 89677Q107 2,249 86,780 SH   DFND 1,7 86,780 0 0
Truist Financial Corp Common / Ordinary Stock 89832Q109 2,841 75,675 SH   DFND 2,4 75,675 0 0
Twilio Inc Common / Ordinary Stock 90138F102 2,316 10,559 SH   DFND 2,3,11 10,559 0 0
Twitter Inc Common / Ordinary Stock 90184L102 4,312 144,774 SH   DFND 1,2,3 144,774 0 0
Tyler Technologies Inc Common / Ordinary Stock 902252105 929 2,680 SH   DFND 2,3 2,680 0 0
Tyson Foods Inc Common / Ordinary Stock 902494103 1,112 18,626 SH   DFND 1,2 18,626 0 0
Uber Technologies Inc Common / Ordinary Stock 90353T100 2,452 78,919 SH   DFND 1,7 78,919 0 0
UBS Group AG Common / Ordinary Stock H42097107 25,766 2,238,922 SH   DFND 1,2,3 2,238,922 0 0
Ulta Beauty Inc Common / Ordinary Stock 90384S303 226 1,115 SH   DFND 2 1,115 0 0
Ultrapar Participacoes SA American Depository Receipts ADR 90400P101 306 90,319 SH   DFND 1 90,319 0 0
Under Armour Inc Common / Ordinary Stock 904311107 1,038 106,669 SH   DFND 1,2 106,669 0 0
Union Pacific Corp Common / Ordinary Stock 907818108 4,640 27,445 SH   DFND 2 27,445 0 0
United Parcel Service Inc Common / Ordinary Stock 911312106 3,180 28,609 SH   DFND 1,2 28,609 0 0
United Rentals Inc Common / Ordinary Stock 911363109 316 2,121 SH   DFND 2 2,121 0 0
United States Steel Corp Common / Ordinary Stock 912909108 1,723 238,766 SH   DFND 1 238,766 0 0
UnitedHealth Group Inc Common / Ordinary Stock 91324P102 10,208 34,612 SH   DFND 1,2,4 34,612 0 0
UNITY Biotechnology Inc Common / Ordinary Stock 91381U101 374 43,172 SH   DFND 2 43,172 0 0
Universal Display Corp Common / Ordinary Stock 91347P105 984 6,580 SH   DFND 2 6,580 0 0
Universal Health Services Inc Common / Ordinary Stock 913903100 1,130 12,168 SH   DFND 2 12,168 0 0
Upwork Inc Common / Ordinary Stock 91688F104 216 15,000 SH   DFND 2 15,000 0 0
Urovant Sciences Ltd Common / Ordinary Stock G9381B108 1,003 101,975 SH   DFND 2 101,975 0 0
US Bancorp Common / Ordinary Stock 902973304 1,180 32,049 SH   DFND 1,2 32,049 0 0
Utilities Select Sector SPDR Fund Exchange Traded Fund 81369Y886 1,855 32,890 SH   DFND 1,2 32,890 0 0
Vale SA American Depository Receipts ADR 91912E105 29,731 2,883,793 SH   DFND 1,2 2,883,793 0 0
Valero Energy Corp Common / Ordinary Stock 91913Y100 2,990 50,836 SH   DFND 1,2 50,836 0 0
VanEck Vectors Gold Miners ETF Exchange Traded Fund 92189F106 538 14,678 SH   DFND 1,7 14,678 0 0
Vanguard FTSE Emerging Markets ETF Exchange Traded Fund 922042858 4,065 102,628 SH   DFND 1,4 102,628 0 0
Vanguard FTSE Europe ETF Exchange Traded Fund 922042874 6,411 127,392 SH   DFND 1,4 127,392 0 0
Vanguard FTSE Pacific ETF Exchange Traded Fund 922042866 1,026 16,127 SH   DFND 4 16,127 0 0
Vanguard Information Technology ETF Exchange Traded Fund 92204A702 280 1,005 SH   DFND 2 1,005 0 0
Vanguard Short-Term Corporate Bond ETF Exchange Traded Fund 92206C409 4,225 51,123 SH   DFND 9 51,123 0 0
Varian Medical Systems Inc Common / Ordinary Stock 92220P105 3,594 29,336 SH   DFND 2,3 29,336 0 0
VBI Vaccines Inc Common / Ordinary Stock 91822J103 353 100,000 SH   DFND 2 100,000 0 0
Ventas Inc Closed-end REIT 92276F100 234 6,394 SH   DFND 2 6,394 0 0
VEON Ltd American Depository Receipts ADR 91822M106 27 15,000 SH   DFND 2 15,000 0 0
VeriSign Inc Common / Ordinary Stock 92343E102 1,458 7,053 SH   DFND 2,3 7,053 0 0
Verisk Analytics Inc Common / Ordinary Stock 92345Y106 1,494 8,780 SH   DFND 2 8,780 0 0
Verizon Communications Inc Common / Ordinary Stock 92343V104 24,768 449,267 SH   DFND 1,2,3,4 449,267 0 0
Verona Pharma PLC American Depository Receipts ADR 925050106 303 60,000 SH   DFND 2 60,000 0 0
Vertex Pharmaceuticals Inc Common / Ordinary Stock 92532F100 2,359 8,129 SH   DFND 2,4,5 8,129 0 0
VF Corp Common / Ordinary Stock 918204108 1,436 23,576 SH   DFND 2 23,576 0 0
ViacomCBS Inc Common / Ordinary Stock 92556H206 222 9,543 SH   DFND 2 9,543 0 0
VICI Properties Inc Closed-end REIT 925652109 438 21,742 SH   DFND 2 21,742 0 0
Vipshop Holdings Ltd American Depository Receipts ADR 92763W103 1,152 57,900 SH   DFND 1,7 57,900 0 0
Visa Inc Common / Ordinary Stock 92826C839 46,619 241,337 SH   DFND 1,2,3,4,7 241,337 0 0
VMware Inc Common / Ordinary Stock 928563402 774 5,000 SH   DFND 2 5,000 0 0
Vulcan Materials Co Common / Ordinary Stock 929160109 262 2,270 SH   DFND 2 2,270 0 0
Walgreens Boots Alliance Inc Common / Ordinary Stock 931427108 2,464 58,138 SH   DFND 1,2,5 58,138 0 0
Walmart Inc Common / Ordinary Stock 931142103 7,068 59,015 SH   DFND 1,2,4 59,015 0 0
Walt Disney Co/The Common / Ordinary Stock 254687106 19,257 172,695 SH   DFND 1,2,3,7 172,695 0 0
Washington Prime Group Inc Closed-end REIT 93964W108 11 13,800 SH   DFND 2 13,800 0 0
Waste Management Inc Common / Ordinary Stock 94106L109 2,573 24,302 SH   DFND 2 24,302 0 0
Wec Energy Group Inc Common / Ordinary Stock 92939U106 473 5,406 SH   DFND 2 5,406 0 0
Weibo Corp American Depository Receipts ADR 948596101 461 13,724 SH   DFND 1,7 13,724 0 0
Wells Fargo & Co Common / Ordinary Stock 949746101 3,016 117,836 SH   DFND 1,2 117,836 0 0
Welltower Inc Closed-end REIT 95040Q104 994 19,210 SH   DFND 1,2 19,210 0 0
West Pharmaceutical Services Inc Common / Ordinary Stock 955306105 286 1,262 SH   DFND 2 1,262 0 0
Western Digital Corp Common / Ordinary Stock 958102105 2,358 53,423 SH   DFND 1,2,3,7 53,423 0 0
Western Union Co/The Common / Ordinary Stock 959802109 1,457 67,410 SH   DFND 1,2 67,410 0 0
Westinghouse Air Brake Technologies Corp Common / Ordinary Stock 929740108 1,221 21,224 SH   DFND 2,7 21,224 0 0
Westrock Co Common / Ordinary Stock 96145D105 1,000 35,409 SH   DFND 2,3 35,409 0 0
WEX Inc Common / Ordinary Stock 96208T104 2,632 15,954 SH   DFND 2,3 15,954 0 0
Weyerhaeuser Co Closed-end REIT 962166104 287 12,788 SH   DFND 2 12,788 0 0
Whirlpool Corp Common / Ordinary Stock 963320106 856 6,612 SH   DFND 1,2,7 6,612 0 0
Williams Cos Inc/The Common / Ordinary Stock 969457100 395 20,791 SH   DFND 2 20,791 0 0
Workday Inc Common / Ordinary Stock 98138H101 1,606 8,576 SH   DFND 2,3,5 8,576 0 0
WW Grainger Inc Common / Ordinary Stock 384802104 875 2,787 SH   DFND 2 2,787 0 0
Wynn Resorts Ltd Common / Ordinary Stock 983134107 6,438 86,431 SH   DFND 1,2,7 86,431 0 0
Xcel Energy Inc Common / Ordinary Stock 98389B100 2,824 45,199 SH   DFND 1,2,4,5 45,199 0 0
Xeris Pharmaceuticals Inc Common / Ordinary Stock 98422L107 163 61,542 SH   DFND 2 61,542 0 0
Xilinx Inc Common / Ordinary Stock 983919101 1,732 17,613 SH   DFND 1,2,3 17,613 0 0
XPO Logistics Inc Common / Ordinary Stock 983793100 1,257 16,280 SH   DFND 1,2 16,280 0 0
Xylem Inc/NY Common / Ordinary Stock 98419M100 200 3,082 SH   DFND 2 3,082 0 0
YPF SA American Depository Receipts ADR 984245100 1,832 318,736 SH   DFND 1,12 318,736 0 0
Yum! Brands Inc Common / Ordinary Stock 988498101 2,860 32,912 SH   DFND 1,2,4 32,912 0 0
Zebra Technologies Corp Common / Ordinary Stock 989207105 3,266 12,764 SH   DFND 2,3 12,764 0 0
Zimmer Biomet Holdings Inc Common / Ordinary Stock 98956P102 1,076 9,017 SH   DFND 2,4 9,017 0 0
Zix Corp Common / Ordinary Stock 98974P100 345 50,000 SH   DFND 2 50,000 0 0
Zoetis Inc Common / Ordinary Stock 98978V103 7,969 58,154 SH   DFND 2,3,4 58,154 0 0
Zogenix Inc Common / Ordinary Stock 98978L204 270 10,000 SH   DFND 2 10,000 0 0
Zoom Video Communications Inc Common / Ordinary Stock 98980L101 1,813 7,152 SH   DFND 2,3 7,152 0 0