The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
1 800 FLOWERS COM INC CL A 68243Q106 757 27,400 SH   DFND 0 0 27,400 0
10X CAPITAL VENTURE ACQU COR COM CL A 88025V107 378 37,784 SH   DFND 0 0 37,784 0
10X GENOMICS INC CL A COM 88025U109 4,319 23,860 SH   DFND 0 0 23,860 0
21VIANET GROUP INC SPONSORED ADS A 90138A103 50,236 1,555,300 SH   DFND 0 0 1,555,300 0
908 DEVICES INC COM 65443P102 737 15,200 SH   DFND 0 0 15,200 0
ABBVIE INC COM 00287Y109 10,822 100,000 SH Put DFND 0 0 100,000 0
ABERCROMBIE & FITCH CO CL A 002896207 8,084 235,606 SH   DFND 0 0 235,606 0
ACADIA HEALTHCARE COMPANY IN COM 00404A109 14,776 258,600 SH   DFND 0 0 258,600 0
ACADIA PHARMACEUTICALS INC COM 004225108 5,132 198,900 SH Call DFND 0 0 198,900 0
ACCENTURE PLC IRELAND SHS CLASS A G1151C101 2,182 7,900 SH   DFND 0 0 7,900 0
ACCOLADE INC COM 00437E102 1,089 24,000 SH   DFND 0 0 24,000 0
ACLARIS THERAPEUTICS INC COM 00461U105 8,261 327,800 SH   DFND 0 0 327,800 0
ACM RESEARCH INC COM CL A 00108J109 808 10,000 SH   DFND 0 0 10,000 0
ACORDA THERAPEUTICS INC COM NEW 00484M601 4,342 891,626 SH   DFND 0 0 891,626 0
ADAPTHEALTH CORP COM CL A 00653Q102 4,558 123,985 SH   DFND 0 0 123,985 0
ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107 10,504 1,978,234 SH   DFND 0 0 1,978,234 0
ADICET BIO INC COM 007002108 13,709 1,048,100 SH   DFND 0 0 1,048,100 0
ADIENT PLC ORD SHS G0084W101 14,813 335,132 SH   DFND 0 0 335,132 0
ADOBE SYSTEMS INCORPORATED COM 00724F101 7,911 16,641 SH   DFND 0 0 16,641 0
ADVANCE AUTO PARTS INC COM 00751Y106 13,147 71,651 SH   DFND 0 0 71,651 0
ADVANCED MICRO DEVICES INC COM 007903107 21,956 279,700 SH   DFND 0 0 279,700 0
ADVERUM BIOTECHNOLOGIES INC COM 00773U108 1,562 158,400 SH Call DFND 0 0 158,400 0
ADVISORSHARES TR PURE US CANNABIS 00768Y453 25,440 600,000 SH Call DFND 0 0 600,000 0
AEGLEA BIOTHERAPEUTICS INC COM 00773J103 11,880 1,500,000 SH   DFND 0 0 1,500,000 0
AEQUI ACQUISITION CORP *W EXP 11/30/202 00775W110 127 133,333 SH   DFND 0 0 133,333 0
AEQUI ACQUISITION CORP COM CL A 00775W102 1,930 200,000 SH   DFND 0 0 200,000 0
AERCAP HOLDINGS NV SHS N00985106 20,266 345,015 SH   DFND 0 0 345,015 0
AES CORP COM 00130H105 35,874 1,338,100 SH   DFND 0 0 1,338,100 0
AFFIMED N V COM N01045108 41,810 5,285,708 SH   DFND 0 0 5,285,708 0
AGENUS INC COM NEW 00847G705 7,164 2,633,800 SH   DFND 0 0 2,633,800 0
AGIOS PHARMACEUTICALS INC COM 00847X104 5,221 101,100 SH   DFND 0 0 101,100 0
AIR PRODS & CHEMS INC COM 009158106 27,241 96,825 SH   DFND 0 0 96,825 0
AJAX I *W EXP 10/27/202 G0190X126 127 75,000 SH   DFND 0 0 75,000 0
AKERNA CORP COM 00973W102 3,458 700,000 SH   DFND 0 0 700,000 0
AKERO THERAPEUTICS INC COM 00973Y108 14,693 506,497 SH   DFND 0 0 506,497 0
ALASKA AIR GROUP INC COM 011659109 57,648 832,945 SH   DFND 0 0 832,945 0
ALBEMARLE CORP COM 012653101 2,645 18,100 SH   DFND 0 0 18,100 0
ALCOA CORP COM 013872106 6,092 187,500 SH   DFND 0 0 187,500 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 58,013 255,867 SH   DFND 0 0 255,867 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 14,511 64,000 SH Call DFND 0 0 64,000 0
ALIGN TECHNOLOGY INC COM 016255101 142,152 262,500 SH   DFND 0 0 262,500 0
ALKERMES PLC SHS G01767105 21,321 1,141,400 SH   DFND 0 0 1,141,400 0
ALLAKOS INC COM 01671P100 13,762 119,900 SH   DFND 0 0 119,900 0
ALLEGRO MICROSYSTEMS INC COM 01749D105 15,571 614,252 SH   DFND 0 0 614,252 0
ALLENA PHARMACEUTICALS COM 018119107 4,170 3,000,000 SH   DFND 0 0 3,000,000 0
ALLETE INC COM NEW 018522300 1,303 19,400 SH   DFND 0 0 19,400 0
ALLIANCE DATA SYSTEMS CORP COM 018581108 25,545 227,901 SH   DFND 0 0 227,901 0
ALLISON TRANSMISSION HLDGS I COM 01973R101 8,452 207,000 SH   DFND 0 0 207,000 0
ALLY FINL INC COM 02005N100 14,928 330,200 SH   DFND 0 0 330,200 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 62,115 439,937 SH   DFND 0 0 439,937 0
ALPHABET INC CAP STK CL A 02079K305 265,615 128,782 SH   DFND 0 0 128,782 0
ALPHABET INC CAP STK CL A 02079K305 11,344 5,500 SH Call DFND 0 0 5,500 0
ALPHATEC HLDGS INC COM NEW 02081G201 10,063 637,300 SH   DFND 0 0 637,300 0
ALTIMAR ACQUISITION CORP SHS CL A G03707109 2,650 268,204 SH   DFND 0 0 268,204 0
ALTIMAR ACQUISITION CORP II UNIT 99/99/9999 G03709113 510 50,000 SH   DFND 0 0 50,000 0
ALTIMETER GROWTH CORP *W EXP 09/30/202 G0370L116 62 20,000 SH   DFND 0 0 20,000 0
ALTIMETER GROWTH CORP CL A G0370L108 585 50,000 SH   DFND 0 0 50,000 0
ALTIMETER GROWTH CORP 2 COM CL A G0371B109 519 50,000 SH   DFND 0 0 50,000 0
ALUSSA ENERGY ACQUISITION CO SHS CL A G0232J101 5,200 520,000 SH   DFND 0 0 520,000 0
AMARIN CORP PLC SPONS ADR NEW 023111206 9,365 1,508,000 SH   DFND 0 0 1,508,000 0
AMAZON COM INC COM 023135106 247,458 79,978 SH   DFND 0 0 79,978 0
AMDOCS LTD SHS G02602103 63,950 911,622 SH   DFND 0 0 911,622 0
AMEDISYS INC COM 023436108 17,902 67,609 SH   DFND 0 0 67,609 0
AMERESCO INC CL A 02361E108 496 10,200 SH   DFND 0 0 10,200 0
AMERICAN EAGLE OUTFITTERS IN COM 02553E106 37,814 1,293,244 SH   DFND 0 0 1,293,244 0
AMERICAN FINL GROUP INC OHIO COM 025932104 13,932 122,100 SH   DFND 0 0 122,100 0
AMERICAN HOMES 4 RENT CL A 02665T306 984 29,500 SH   DFND 0 0 29,500 0
AMERICAN TOWER CORP NEW COM 03027X100 7,172 30,000 SH   DFND 0 0 30,000 0
AMETEK INC COM 031100100 16,158 126,500 SH   DFND 0 0 126,500 0
AMICUS THERAPEUTICS INC COM 03152W109 1,752 177,322 SH   DFND 0 0 177,322 0
AMNEAL PHARMACEUTICALS INC COM STK CL A 03168L105 19,732 2,931,900 SH   DFND 0 0 2,931,900 0
ANALOG DEVICES INC COM 032654105 58,193 375,247 SH   DFND 0 0 375,247 0
ANAPLAN INC COM 03272L108 120,227 2,232,630 SH   DFND 0 0 2,232,630 0
ANGI INC COM CL A NEW 00183L102 43,439 3,341,499 SH   DFND 0 0 3,341,499 0
ANGIODYNAMICS INC COM 03475V101 10,081 430,809 SH   DFND 0 0 430,809 0
ANNEXON INC COM 03589W102 6,918 248,494 SH   DFND 0 0 248,494 0
ANTERO RESOURCES CORP COM 03674X106 4,836 474,121 SH   DFND 0 0 474,121 0
ANTHEM INC COM 036752103 12,384 34,500 SH   DFND 0 0 34,500 0
AON PLC SHS CL A G0403H108 34,044 147,945 SH   DFND 0 0 147,945 0
APA CORPORATION COM 03743Q108 14,752 824,147 SH   DFND 0 0 824,147 0
APELLIS PHARMACEUTICALS INC COM 03753U106 10,728 250,000 SH   DFND 0 0 250,000 0
APOLLO STRATEGIC GROWTH CAPT SHS CL A G0411R106 5,013 506,367 SH   DFND 0 0 506,367 0
APPLIED MATLS INC COM 038222105 255,171 1,909,964 SH   DFND 0 0 1,909,964 0
APPLIED THERAPEUTICS INC COM 03828A101 5,595 298,300 SH   DFND 0 0 298,300 0
APTIV PLC SHS G6095L109 15,953 115,684 SH   DFND 0 0 115,684 0
ARAMARK COM 03852U106 16,619 439,900 SH   DFND 0 0 439,900 0
ARBUTUS BIOPHARMA CORP COM 03879J100 3,456 1,037,700 SH   DFND 0 0 1,037,700 0
ARCELORMITTAL SA LUXEMBOURG NY REGISTRY SH 03938L203 1,867 64,000 SH   DFND 0 0 64,000 0
ARCELORMITTAL SA LUXEMBOURG NY REGISTRY SH 03938L203 14,585 500,000 SH Call DFND 0 0 500,000 0
ARCH CAP GROUP LTD ORD G0450A105 41,497 1,081,485 SH   DFND 0 0 1,081,485 0
ARCH RESOURCES INC CL A 03940R107 6,219 149,500 SH   DFND 0 0 149,500 0
ARCUS BIOSCIENCES INC COM 03969F109 1,767 62,926 SH   DFND 0 0 62,926 0
ARCUTIS BIOTHERAPEUTICS INC COM 03969K108 12,709 439,300 SH   DFND 0 0 439,300 0
ARES ACQUISITION CORPORATION UNIT 99/99/9999 G33032114 16,000 1,600,000 SH   DFND 0 0 1,600,000 0
ARGENX SE SPONSORED ADR 04016X101 13,632 49,500 SH   DFND 0 0 49,500 0
ARISTA NETWORKS INC COM 040413106 7,245 24,000 SH   DFND 0 0 24,000 0
ARRAY TECHNOLOGIES INC COM SHS 04271T100 20,451 685,800 SH   DFND 0 0 685,800 0
ARVINAS INC COM 04335A105 74,567 1,128,100 SH   DFND 0 0 1,128,100 0
ARYA SCIENCES ACQUISITION CO COM CL A G3166W106 1,812 131,476 SH   DFND 0 0 131,476 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 4,511 35,000 SH   DFND 0 0 35,000 0
ASML HOLDING N V N Y REGISTRY SHS N07059210 21,855 35,400 SH   DFND 0 0 35,400 0
ASTRAZENECA PLC SPONSORED ADR 046353108 176,648 3,552,847 SH   DFND 0 0 3,552,847 0
ATARA BIOTHERAPEUTICS INC COM 046513107 7,713 537,100 SH   DFND 0 0 537,100 0
ATHIRA PHARMA INC COM 04746L104 8,155 443,200 SH   DFND 0 0 443,200 0
ATLAS CREST INVT CORP COM 049284102 2,636 262,308 SH   DFND 0 0 262,308 0
ATLASSIAN CORP PLC CL A G06242104 7,284 34,560 SH   DFND 0 0 34,560 0
AURINIA PHARMACEUTICALS INC COM 05156V102 4,085 314,565 SH   DFND 0 0 314,565 0
AURORA CANNABIS INC COM 05156X884 2,806 301,400 SH   DFND 0 0 301,400 0
AUTODESK INC COM 052769106 63,030 227,422 SH   DFND 0 0 227,422 0
AUTOZONE INC COM 053332102 21,497 15,308 SH   DFND 0 0 15,308 0
AVANTOR INC COM 05352A100 16,852 582,500 SH   DFND 0 0 582,500 0
AVIS BUDGET GROUP COM 053774105 28,617 394,500 SH   DFND 0 0 394,500 0
AVNET INC COM 053807103 4,796 115,538 SH   DFND 0 0 115,538 0
AVROBIO INC COM 05455M100 5,091 401,200 SH   DFND 0 0 401,200 0
AXOGEN INC COM 05463X106 12,434 613,733 SH   DFND 0 0 613,733 0
AXONICS MODULATION TECHNOLOG COM 05465P101 9,929 165,787 SH   DFND 0 0 165,787 0
AXSOME THERAPEUTICS INC COM 05464T104 2,395 42,300 SH   DFND 0 0 42,300 0
AZURE PWR GLOBAL LTD SHS V0393H103 3,024 111,200 SH   DFND 0 0 111,200 0
BAIDU INC SPON ADR REP A 056752108 348,602 1,602,400 SH   DFND 0 0 1,602,400 0
BANDWIDTH INC COM CL A 05988J103 35,639 281,200 SH   DFND 0 0 281,200 0
BANK NEW YORK MELLON CORP COM 064058100 18,240 385,700 SH   DFND 0 0 385,700 0
BAXTER INTL INC COM 071813109 49,643 588,600 SH   DFND 0 0 588,600 0
BELLUS HEALTH INC NEW COM NEW 07987C204 22,272 5,800,000 SH   DFND 0 0 5,800,000 0
BERKLEY W R CORP COM 084423102 1,884 25,000 SH   DFND 0 0 25,000 0
BICYCLE THERAPEUTICS PLC SPONSORED ADS 088786108 47,120 1,577,493 SH   DFND 0 0 1,577,493 0
BILL COM HLDGS INC COM 090043100 11,761 80,834 SH   DFND 0 0 80,834 0
BIOGEN INC COM 09062X103 32,283 115,400 SH   DFND 0 0 115,400 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 19,368 256,500 SH   DFND 0 0 256,500 0
BIO-TECHNE CORP COM 09073M104 37,066 97,048 SH   DFND 0 0 97,048 0
BJS RESTAURANTS INC COM 09180C106 7,184 123,700 SH   DFND 0 0 123,700 0
BK OF AMERICA CORP COM 060505104 37,303 964,152 SH   DFND 0 0 964,152 0
BLINK CHARGING CO COM 09354A100 2,047 49,810 SH   DFND 0 0 49,810 0
BOEING CO COM 097023105 38,633 151,669 SH   DFND 0 0 151,669 0
BOOKING HOLDINGS INC COM 09857L108 139,404 59,834 SH   DFND 0 0 59,834 0
BOOT BARN HLDGS INC COM 099406100 3,613 57,978 SH   DFND 0 0 57,978 0
BOSTON BEER INC CL A 100557107 26,367 21,858 SH   DFND 0 0 21,858 0
BRIDGETOWN HOLDINGS LTD *W EXP 09/30/202 G1355U121 94 33,333 SH   DFND 0 0 33,333 0
BRIGHTSPHERE INVT GROUP INC COM 10948W103 22,837 1,120,546 SH   DFND 0 0 1,120,546 0
BRINKS CO COM 109696104 6,259 79,000 SH   DFND 0 0 79,000 0
BRISTOL-MYERS SQUIBB CO COM 110122108 16,357 259,100 SH   DFND 0 0 259,100 0
BROOKFIELD RENEWABLE PARTNER PARTNERSHIP UNIT G16258108 1,444 33,900 SH   DFND 0 0 33,900 0
BROWN FORMAN CORP CL B 115637209 8,831 128,047 SH   DFND 0 0 128,047 0
BRUNSWICK CORP COM 117043109 12,568 131,785 SH   DFND 0 0 131,785 0
BTRS HOLDINGS INC COM CL 1 11778X104 3,372 233,000 SH   DFND 0 0 233,000 0
BUCKLE INC COM 118440106 2,502 63,700 SH   DFND 0 0 63,700 0
BUILDERS FIRSTSOURCE INC COM 12008R107 4,045 87,241 SH   DFND 0 0 87,241 0
BUNGE LIMITED COM G16962105 25,426 320,750 SH   DFND 0 0 320,750 0
BURLINGTON STORES INC COM 122017106 621 2,079 SH   DFND 0 0 2,079 0
CACI INTL INC CL A 127190304 39,395 159,715 SH   DFND 0 0 159,715 0
CAESARS ENTERTAINMENT INC NE COM 12769G100 38,538 440,687 SH   DFND 0 0 440,687 0
CAESARS ENTERTAINMENT INC NE COM 12769G100 4,373 50,000 SH Call DFND 0 0 50,000 0
CALITHERA BIOSCIENCES INC COM 13089P101 1,840 760,500 SH   DFND 0 0 760,500 0
CALIX INC COM 13100M509 2,296 66,244 SH   DFND 0 0 66,244 0
CALLON PETE CO DEL COM 13123X508 3,797 98,490 SH   DFND 0 0 98,490 0
CAMECO CORP COM 13321L108 1,661 100,000 SH   DFND 0 0 100,000 0
CAMPBELL SOUP CO COM 134429109 13,064 259,883 SH   DFND 0 0 259,883 0
CANAAN INC SPONSORED ADS 134748102 2,110 102,100 SH   DFND 0 0 102,100 0
CANADIAN NAT RES LTD COM 136385101 11,207 363,000 SH   DFND 0 0 363,000 0
CANADIAN NATL RY CO COM 136375102 71,202 613,868 SH   DFND 0 0 613,868 0
CAPITAL ONE FINL CORP COM 14040H105 89,861 706,289 SH   DFND 0 0 706,289 0
CAPRI HOLDINGS LIMITED SHS G1890L107 75,005 1,470,690 SH   DFND 0 0 1,470,690 0
CAPRI HOLDINGS LIMITED SHS G1890L107 5,095 99,900 SH Call DFND 0 0 99,900 0
CARDINAL HEALTH INC COM 14149Y108 10,285 169,300 SH   DFND 0 0 169,300 0
CARGURUS INC COM CL A 141788109 12,206 512,200 SH   DFND 0 0 512,200 0
CARRIER GLOBAL CORPORATION COM 14448C104 5,537 131,157 SH   DFND 0 0 131,157 0
CARVANA CO CL A 146869102 48,767 185,851 SH   DFND 0 0 185,851 0
CATCHA INVESTMENT CORP UNIT 99/99/9999 G1962Y128 988 99,340 SH   DFND 0 0 99,340 0
CATERPILLAR INC COM 149123101 20,208 87,153 SH   DFND 0 0 87,153 0
CBOE GLOBAL MKTS INC COM 12503M108 19,975 202,400 SH   DFND 0 0 202,400 0
CDK GLOBAL INC COM 12508E101 3,761 69,564 SH   DFND 0 0 69,564 0
CELANESE CORP DEL COM 150870103 11,521 76,906 SH   DFND 0 0 76,906 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 950 46,100 SH   DFND 0 0 46,100 0
CELSIUS HLDGS INC COM NEW 15118V207 937 19,500 SH   DFND 0 0 19,500 0
CEMEX SAB DE CV SPON ADR NEW 151290889 2,788 400,000 SH Call DFND 0 0 400,000 0
CENOVUS ENERGY INC COM 15135U109 36,020 4,793,773 SH   DFND 0 0 4,793,773 0
CENTENE CORP DEL COM 15135B101 86,904 1,359,794 SH   DFND 0 0 1,359,794 0
CENTENNIAL RESOURCE DEV INC CL A 15136A102 992 236,124 SH   DFND 0 0 236,124 0
CENTERPOINT ENERGY INC COM 15189T107 17,963 793,070 SH   DFND 0 0 793,070 0
CERECOR INC COM 15671L109 7,399 2,450,000 SH   DFND 0 0 2,450,000 0
CEREVEL THERAPEUTICS HLDNG I *W EXP 06/09/202 15678U102 970 224,999 SH   DFND 0 0 224,999 0
CEREVEL THERAPEUTICS HLDNG I COM 15678U128 4,074 296,700 SH   DFND 0 0 296,700 0
CERNER CORP COM 156782104 33,086 460,297 SH   DFND 0 0 460,297 0
CF FIN ACQUISITION CORP III CL A 12529D108 3,000 300,000 SH   DFND 0 0 300,000 0
CF INDS HLDGS INC COM 125269100 7,479 164,800 SH   DFND 0 0 164,800 0
CHAMPIONX CORPORATION COM 15872M104 7,648 351,964 SH   DFND 0 0 351,964 0
CHARGEPOINT HOLDINGS INC COM CL A 15961R105 5,640 211,231 SH   DFND 0 0 211,231 0
CHARLES RIV LABS INTL INC COM 159864107 44,640 154,022 SH   DFND 0 0 154,022 0
CHESAPEAKE ENERGY CORP COM 165167735 5,099 117,513 SH   DFND 0 0 117,513 0
CHILDRENS PL INC NEW COM 168905107 11,779 168,996 SH   DFND 0 0 168,996 0
CHIMERIX INC COM 16934W106 44,179 4,582,872 SH   DFND 0 0 4,582,872 0
CHINOOK THERAPEUTICS INC COM 16961L106 18,185 1,170,198 SH   DFND 0 0 1,170,198 0
CHUBB LIMITED COM H1467J104 53,338 337,644 SH   DFND 0 0 337,644 0
CHURCHILL CAPITAL CORP IV *W EXP 08/04/202 171439110 112 10,000 SH   DFND 0 0 10,000 0
CHURCHILL CAPITAL CORP V *W EXP 10/29/202 17144T115 32 25,000 SH   DFND 0 0 25,000 0
CHURCHILL CAPITAL CORP V COM CL A 17144T107 494 50,000 SH   DFND 0 0 50,000 0
CHURCHILL CAPITAL CORP VII UNIT 99/99/9999 17144M201 748 75,000 SH   DFND 0 0 75,000 0
CIMAREX ENERGY CO COM 171798101 37,477 631,040 SH   DFND 0 0 631,040 0
CINEMARK HLDGS INC COM 17243V102 1,654 81,062 SH   DFND 0 0 81,062 0
CISCO SYS INC COM 17275R102 13,492 260,922 SH   DFND 0 0 260,922 0
CITI TRENDS INC COM 17306X102 6,359 75,900 SH   DFND 0 0 75,900 0
CITIGROUP INC COM NEW 172967424 29,100 400,000 SH   DFND 0 0 400,000 0
CLEAN ENERGY FUELS CORP COM 184499101 1,035 75,300 SH   DFND 0 0 75,300 0
CLEANSPARK INC COM NEW 18452B209 10,132 425,352 SH   DFND 0 0 425,352 0
CLEVELAND-CLIFFS INC NEW COM 185899101 13,094 651,100 SH   DFND 0 0 651,100 0
CLIMATE CHANGE CRISIS REAL I CL A COM 18716C100 6,629 483,853 SH   DFND 0 0 483,853 0
CLIMATE REAL IMPACT SLUTINS UNIT 99/99/9999 187171202 8,890 889,000 SH   DFND 0 0 889,000 0
CLOUDERA INC COM 18914U100 6,979 573,500 SH   DFND 0 0 573,500 0
CMC MATERIALS INC COM 12571T100 126,656 716,421 SH   DFND 0 0 716,421 0
CME GROUP INC COM 12572Q105 12,260 60,032 SH   DFND 0 0 60,032 0
CMS ENERGY CORP COM 125896100 9,863 161,108 SH   DFND 0 0 161,108 0
CNA FINL CORP COM 126117100 1,410 31,600 SH   DFND 0 0 31,600 0
CNX RES CORP COM 12653C108 8,717 593,000 SH   DFND 0 0 593,000 0
COCA COLA CO COM 191216100 3,972 75,351 SH   DFND 0 0 75,351 0
COCA COLA EUROPEAN PARTNERS SHS G25839104 17,701 339,369 SH   DFND 0 0 339,369 0
COHN ROBBINS HOLDINGS CORP *W EXP 08/28/202 G23726113 100 83,333 SH   DFND 0 0 83,333 0
COHN ROBBINS HOLDINGS CORP COM CL A G23726105 492 50,000 SH   DFND 0 0 50,000 0
COLFAX CORP COM 194014106 7,904 180,422 SH   DFND 0 0 180,422 0
COLLEGIUM PHARMACEUTICAL INC COM 19459J104 3,164 133,522 SH   DFND 0 0 133,522 0
COLONY CAP INC NEW CL A COM 19626G108 14,137 2,181,652 SH   DFND 0 0 2,181,652 0
COMCAST CORP NEW CL A 20030N101 13,246 244,800 SH   DFND 0 0 244,800 0
COMMERCIAL METALS CO COM 201723103 885 28,700 SH   DFND 0 0 28,700 0
CONOCOPHILLIPS COM 20825C104 22,192 418,962 SH   DFND 0 0 418,962 0
CONSTELLATION PHARMCETICLS I COM 210373106 2,688 114,932 SH   DFND 0 0 114,932 0
CONTEXTLOGIC INC COM CL A 21077C107 11,316 716,224 SH   DFND 0 0 716,224 0
CONTINENTAL RES INC COM 212015101 22,552 871,759 SH   DFND 0 0 871,759 0
CONX CORP *W EXP 10/30/202 212873111 77 62,500 SH   DFND 0 0 62,500 0
COPA HOLDINGS SA CL A P31076105 9,466 117,169 SH   DFND 0 0 117,169 0
COPART INC COM 217204106 112,913 1,039,618 SH   DFND 0 0 1,039,618 0
CORESITE RLTY CORP COM 21870Q105 17,594 146,800 SH   DFND 0 0 146,800 0
COSTAR GROUP INC COM 22160N109 493 600 SH   DFND 0 0 600 0
COSTCO WHSL CORP NEW COM 22160K105 40,113 113,803 SH   DFND 0 0 113,803 0
COURSERA INC COM 22266M104 2,250 50,000 SH   DFND 0 0 50,000 0
CRACKER BARREL OLD CTRY STOR COM 22410J106 19,259 111,400 SH   DFND 0 0 111,400 0
CRINETICS PHARMACEUTICALS IN COM 22663K107 19,482 1,275,000 SH   DFND 0 0 1,275,000 0
CROCS INC COM 227046109 19,042 236,692 SH   DFND 0 0 236,692 0
CROWDSTRIKE HLDGS INC CL A 22788C105 9,978 54,673 SH   DFND 0 0 54,673 0
CROWN CASTLE INTL CORP NEW COM 22822V101 7,780 45,200 SH   DFND 0 0 45,200 0
CROWN HLDGS INC COM 228368106 64,519 664,867 SH   DFND 0 0 664,867 0
CSX CORP COM 126408103 27,291 283,048 SH   DFND 0 0 283,048 0
CUBESMART COM 229663109 3,303 87,300 SH   DFND 0 0 87,300 0
CURIS INC COM NEW 231269200 63,622 5,620,291 SH   DFND 0 0 5,620,291 0
CURIS INC COM NEW 231269200 5,660 500,000 SH Call DFND 0 0 500,000 0
CUSHMAN WAKEFIELD PLC SHS G2717B108 987 60,500 SH   DFND 0 0 60,500 0
CYBERARK SOFTWARE LTD SHS M2682V108 2,031 15,700 SH   DFND 0 0 15,700 0
CYCLACEL PHARMACEUTICALS INC COM 23254L603 1,635 230,000 SH   DFND 0 0 230,000 0
CYTOKINETICS INC COM NEW 23282W605 8,713 374,600 SH   DFND 0 0 374,600 0
CYTOMX THERAPEUTICS INC COM 23284F105 48,970 6,335,000 SH   DFND 0 0 6,335,000 0
D R HORTON INC COM 23331A109 6,668 74,820 SH   DFND 0 0 74,820 0
DANAHER CORPORATION COM 235851102 74,541 331,177 SH   DFND 0 0 331,177 0
DARDEN RESTAURANTS INC COM 237194105 77,459 545,483 SH   DFND 0 0 545,483 0
DARLING INGREDIENTS INC COM 237266101 24,336 330,743 SH   DFND 0 0 330,743 0
DAVE & BUSTERS ENTMT INC COM 238337109 2,986 62,332 SH   DFND 0 0 62,332 0
DAVE & BUSTERS ENTMT INC COM 238337109 4,790 100,000 SH Call DFND 0 0 100,000 0
DEEP LAKE CAPITAL ACQUSTN CO UNIT 01/04/2026 G27029126 2,515 250,000 SH   DFND 0 0 250,000 0
DEERFIELD HEALTHCARE TECH AC COM CL A 244413100 2,652 218,804 SH   DFND 0 0 218,804 0
DELEK US HLDGS INC NEW COM 24665A103 2,283 104,800 SH   DFND 0 0 104,800 0
DELL TECHNOLOGIES INC CL C 24703L202 130,938 1,485,400 SH   DFND 0 0 1,485,400 0
DELTA AIR LINES INC DEL COM NEW 247361702 18,959 392,692 SH   DFND 0 0 392,692 0
DELTA AIR LINES INC DEL COM NEW 247361702 4,828 100,000 SH Call DFND 0 0 100,000 0
DENBURY INC COM 24790A101 10,822 225,970 SH   DFND 0 0 225,970 0
DENTSPLY SIRONA INC COM 24906P109 7,150 112,050 SH   DFND 0 0 112,050 0
DESPEGAR COM CORP ORD SHS G27358103 7,287 534,600 SH   DFND 0 0 534,600 0
DEVON ENERGY CORP NEW COM 25179M103 63,553 2,908,605 SH   DFND 0 0 2,908,605 0
DEXCOM INC COM 252131107 11,500 32,000 SH   DFND 0 0 32,000 0
DIAMEDICA THERAPEUTICS INC COM NEW 25253X207 5,053 552,250 SH   DFND 0 0 552,250 0
DICERNA PHARMACEUTICALS INC COM 253031108 15,507 606,439 SH   DFND 0 0 606,439 0
DICKS SPORTING GOODS INC COM 253393102 3,689 48,443 SH   DFND 0 0 48,443 0
DIGITALOCEAN HLDGS INC COM 25402D102 1,053 25,000 SH   DFND 0 0 25,000 0
DILLARDS INC CL A 254067101 1,970 20,400 SH   DFND 0 0 20,400 0
DISCOVER FINL SVCS COM 254709108 4,750 50,000 SH   DFND 0 0 50,000 0
DISCOVERY INC COM SER C 25470F302 8,263 224,000 SH   DFND 0 0 224,000 0
DISRUPTIVE ACQUISITION CORP UNIT 03/06/2026 G2770Y110 1,482 150,000 SH   DFND 0 0 150,000 0
DIVERSEY HLDGS LTD ORD SHS G28923103 11,966 813,487 SH   DFND 0 0 813,487 0
DMY TECHNOLOGY GROUP INC II COM CL A 233277102 3,851 261,774 SH   DFND 0 0 261,774 0
DMY TECHNOLOGY GROUP INC III *W EXP 99/99/999 233278118 173 75,000 SH   DFND 0 0 75,000 0
DMY TECHNOLOGY GROUP INC III COM CLASS A 233278100 539 50,000 SH   DFND 0 0 50,000 0
DOCUSIGN INC COM 256163106 537 2,651 SH   DFND 0 0 2,651 0
DOLBY LABORATORIES INC COM CL A 25659T107 7,967 80,700 SH   DFND 0 0 80,700 0
DOLLAR GEN CORP NEW COM 256677105 98,917 488,190 SH   DFND 0 0 488,190 0
DOLLAR TREE INC COM 256746108 25,946 226,678 SH   DFND 0 0 226,678 0
DOMINION ENERGY INC COM 25746U109 53,012 697,894 SH   DFND 0 0 697,894 0
DOMTAR CORP COM NEW 257559203 4,622 125,100 SH   DFND 0 0 125,100 0
DOVER CORP COM 260003108 6,857 50,000 SH   DFND 0 0 50,000 0
DPCM CAP INC *W EXP 10/14/202 23344P119 42 33,333 SH   DFND 0 0 33,333 0
DRAFTKINGS INC COM CL A 26142R104 12,266 200,000 SH Put DFND 0 0 200,000 0
DRAGONEER GROWTH OPPORTUN CO *W EXP 08/18/202 G28302118 16 10,000 SH   DFND 0 0 10,000 0
DRAGONEER GROWTH OPPORTUN CO COM CL A G28302100 508 50,000 SH   DFND 0 0 50,000 0
DRAGONEER GROWTH OPPTY CORP SHS CL A G28314105 514 50,000 SH   DFND 0 0 50,000 0
DRIVEN BRANDS HLDGS INC COM 26210V102 6,408 252,100 SH   DFND 0 0 252,100 0
DUCKHORN PORTFOLIO INC COM 26414D106 1,695 101,000 SH   DFND 0 0 101,000 0
DUKE ENERGY CORP NEW COM NEW 26441C204 2,568 26,600 SH   DFND 0 0 26,600 0
DUPONT DE NEMOURS INC COM 26614N102 25,129 325,164 SH   DFND 0 0 325,164 0
DXC TECHNOLOGY CO COM 23355L106 234,999 7,517,578 SH   DFND 0 0 7,517,578 0
DYNATRACE INC COM NEW 268150109 4,598 95,314 SH   DFND 0 0 95,314 0
DYNE THERAPEUTICS INC COM 26818M108 5,484 353,115 SH   DFND 0 0 353,115 0
E L F BEAUTY INC COM 26856L103 11,284 420,573 SH   DFND 0 0 420,573 0
E2OPEN PARENT HOLDINGS INC COM CL A 29788T103 530 53,200 SH   DFND 0 0 53,200 0
EAGLE MATLS INC COM 26969P108 16,796 124,961 SH   DFND 0 0 124,961 0
EARGO INC COM 270087109 6,411 128,353 SH   DFND 0 0 128,353 0
EAST STONE ACQUISITION CORP SHS G2911D108 1,499 150,000 SH   DFND 0 0 150,000 0
EATON CORP PLC SHS G29183103 6,333 45,800 SH   DFND 0 0 45,800 0
EDWARDS LIFESCIENCES CORP COM 28176E108 48,439 579,142 SH   DFND 0 0 579,142 0
EHEALTH INC COM 28238P109 9,579 131,700 SH   DFND 0 0 131,700 0
ELANCO ANIMAL HEALTH INC COM 28414H103 70,383 2,389,900 SH   DFND 0 0 2,389,900 0
ELASTIC N V ORD SHS N14506104 55,063 495,175 SH   DFND 0 0 495,175 0
ELEDON PHARMACEUTICALS INC COM 28617K101 1,338 125,000 SH   DFND 0 0 125,000 0
ENCOMPASS HEALTH CORP COM 29261A100 40,426 493,600 SH   DFND 0 0 493,600 0
ENERGIZER HLDGS INC NEW COM 29272W109 1,414 29,800 SH   DFND 0 0 29,800 0
ENERPLUS CORP COM 292766102 2,008 400,000 SH   DFND 0 0 400,000 0
ENLINK MIDSTREAM LLC COM UNIT REP LTD 29336T100 2,616 609,700 SH   DFND 0 0 609,700 0
ENPHASE ENERGY INC COM 29355A107 31,066 191,576 SH   DFND 0 0 191,576 0
ENTERGY CORP NEW COM 29364G103 66,954 673,107 SH   DFND 0 0 673,107 0
EPAM SYS INC COM 29414B104 476 1,200 SH   DFND 0 0 1,200 0
EQUINOR ASA SPONSORED ADR 29446M102 33,693 1,731,422 SH   DFND 0 0 1,731,422 0
EQUITABLE HLDGS INC COM 29452E101 24,041 737,000 SH   DFND 0 0 737,000 0
ERICSSON ADR B SEK 10 294821608 25,031 1,897,700 SH   DFND 0 0 1,897,700 0
ESPERION THERAPEUTICS INC NE COM 29664W105 18,182 648,200 SH   DFND 0 0 648,200 0
ETF MANAGERS TR ETFMG ALTR HRVST 26924G508 8,015 350,000 SH Call DFND 0 0 350,000 0
ETSY INC COM 29786A106 4,033 20,000 SH Call DFND 0 0 20,000 0
EURONET WORLDWIDE INC COM 298736109 16,472 119,100 SH   DFND 0 0 119,100 0
EUROPEAN SUSTAINABLE GROWTH UNIT 01/18/2024 G3194F125 249 25,000 SH   DFND 0 0 25,000 0
EVERGY INC COM 30034W106 50,760 852,686 SH   DFND 0 0 852,686 0
EVOFEM BIOSCIENCES INC COM 30048L104 545 311,170 SH   DFND 0 0 311,170 0
EVOLENT HEALTH INC CL A 30050B101 10,805 534,889 SH   DFND 0 0 534,889 0
EVOLUS INC COM 30052C107 1,034 79,600 SH   DFND 0 0 79,600 0
EXECUTIVE NETWORK PARTNERING *W EXP 09/25/202 30158L118 53 62,500 SH   DFND 0 0 62,500 0
EXELIXIS INC COM 30161Q104 38,092 1,686,254 SH   DFND 0 0 1,686,254 0
EXELON CORP COM 30161N101 26,765 611,900 SH   DFND 0 0 611,900 0
EXPEDIA GROUP INC COM NEW 30212P303 134,184 779,595 SH   DFND 0 0 779,595 0
EXTRA SPACE STORAGE INC COM 30225T102 3,473 26,200 SH   DFND 0 0 26,200 0
FABRINET SHS G3323L100 9,003 99,600 SH   DFND 0 0 99,600 0
FACEBOOK INC CL A 30303M102 241,598 820,283 SH   DFND 0 0 820,283 0
FALCON CAPITAL ACQUISITN COR *W EXP 08/20/202 30606L116 128 83,333 SH   DFND 0 0 83,333 0
FALCON CAPITAL ACQUISITN COR COM CL A 30606L108 734 73,602 SH   DFND 0 0 73,602 0
FARFETCH LTD ORD SH CL A 30744W107 17,894 337,500 SH   DFND 0 0 337,500 0
FEDEX CORP COM 31428X106 60,656 213,547 SH   DFND 0 0 213,547 0
FG NEW AMER ACQUISITION CORP *W EXP 08/31/202 30259V114 100 64,883 SH   DFND 0 0 64,883 0
FIDELITY NATL INFORMATION SV COM 31620M106 1,842 13,097 SH   DFND 0 0 13,097 0
FIFTH THIRD BANCORP COM 316773100 4,535 121,100 SH   DFND 0 0 121,100 0
FINCH THERAPEUTICS GROUP INC COM 31773D101 23 1,433 SH   DFND 0 0 1,433 0
FINTECH ACQUISITION CORP IV CL A 31810N104 3,354 300,000 SH   DFND 0 0 300,000 0
FIRST BANCORP P R COM NEW 318672706 23,350 2,073,700 SH   DFND 0 0 2,073,700 0
FIRST CTZNS BANCSHARES INC N CL A 31946M103 8,358 10,000 SH   DFND 0 0 10,000 0
FIRSTENERGY CORP COM 337932107 13,013 375,112 SH   DFND 0 0 375,112 0
FIVE BELOW INC COM 33829M101 34,591 181,304 SH   DFND 0 0 181,304 0
FIVE9 INC COM 338307101 100,411 642,300 SH   DFND 0 0 642,300 0
FLEX LTD ORD Y2573F102 20,599 1,125,000 SH   DFND 0 0 1,125,000 0
FLOOR & DECOR HLDGS INC CL A 339750101 14,818 155,190 SH   DFND 0 0 155,190 0
FOGHORN THERAPEUTICS INC COM 344174107 1,439 109,200 SH   DFND 0 0 109,200 0
FOLEY TRASIMENE ACQUISTN COR COM CL A 34431F104 36,144 3,600,000 SH   DFND 0 0 3,600,000 0
FOOT LOCKER INC COM 344849104 990 17,600 SH   DFND 0 0 17,600 0
FOREST ROAD ACQUISITION CORP COM 34619R102 4,654 459,882 SH   DFND 0 0 459,882 0
FORTE BIOSCIENCES INC COM 34962G109 17,142 500,200 SH   DFND 0 0 500,200 0
FORTIS INC COM 349553107 1,996 46,000 SH   DFND 0 0 46,000 0
FOSSIL GROUP INC COM 34988V106 810 65,300 SH   DFND 0 0 65,300 0
FOX CORP CL A COM 35137L105 11,579 320,653 SH   DFND 0 0 320,653 0
FOX CORP CL B COM 35137L204 3,616 103,518 SH   DFND 0 0 103,518 0
FRESHPET INC COM 358039105 3,887 24,477 SH   DFND 0 0 24,477 0
FRONTLINE LTD SHS NEW G3682E192 2,811 393,100 SH   DFND 0 0 393,100 0
F-STAR THERAPEUTICS INC COM 30315R107 812 75,000 SH   DFND 0 0 75,000 0
FTAC OLYMPUS ACQUISITION COR CL A SHS G37288100 20,612 1,950,000 SH   DFND 0 0 1,950,000 0
FULCRUM THERAPEUTICS INC COM 359616109 6,776 575,246 SH   DFND 0 0 575,246 0
FUSION PHARMACEUTICALS INC COM 36118A100 8,040 750,000 SH   DFND 0 0 750,000 0
G III APPAREL GROUP LTD COM 36237H101 1,766 58,600 SH   DFND 0 0 58,600 0
G1 THERAPEUTICS INC COM 3621LQ109 3,607 149,936 SH   DFND 0 0 149,936 0
GALAPAGOS NV SPON ADR 36315X101 35,884 465,478 SH   DFND 0 0 465,478 0
GAP INC COM 364760108 23,589 792,114 SH   DFND 0 0 792,114 0
GAP INC COM 364760108 7,445 250,000 SH Call DFND 0 0 250,000 0
GCM GROSVENOR INC COM CL A 36831E108 4,046 340,000 SH   DFND 0 0 340,000 0
GDS HLDGS LTD SPONSORED ADS 36165L108 1,492 18,400 SH   DFND 0 0 18,400 0
GEMINI THERAPEUTICS INC COM 36870G105 6,511 480,500 SH   DFND 0 0 480,500 0
GENERAL MLS INC COM 370334104 6,132 100,000 SH Call DFND 0 0 100,000 0
GENERAL MTRS CO COM 37045V100 45,976 800,140 SH   DFND 0 0 800,140 0
GENMAB A/S SPONSORED ADS 372303206 7,508 228,700 SH   DFND 0 0 228,700 0
GIGCAPITAL3 INC COM 37519D107 2,668 250,000 SH   DFND 0 0 250,000 0
GILEAD SCIENCES INC COM 375558103 117,203 1,813,444 SH   DFND 0 0 1,813,444 0
GLOBAL BLOOD THERAPEUTICS IN COM 37890U108 54,013 1,325,482 SH   DFND 0 0 1,325,482 0
GLOBAL PMTS INC COM 37940X102 16,491 81,807 SH   DFND 0 0 81,807 0
GLOBAL SYNERGY ACQUISIT CORP UNIT 01/01/2024 G3934J114 996 100,000 SH   DFND 0 0 100,000 0
GLOBUS MED INC CL A 379577208 1,930 31,300 SH   DFND 0 0 31,300 0
GOODYEAR TIRE & RUBR CO COM 382550101 19,634 1,117,454 SH   DFND 0 0 1,117,454 0
GOPRO INC CL A 38268T103 1,034 88,800 SH   DFND 0 0 88,800 0
GORES HLDGS V INC COM CL A 382864106 2,994 300,000 SH   DFND 0 0 300,000 0
GORES HOLDINGS VI INC *W EXP 08/24/202 38286R113 758 192,000 SH   DFND 0 0 192,000 0
GRAFTECH INTL LTD COM 384313508 8,418 688,300 SH   DFND 0 0 688,300 0
GREEN DOT CORP CL A 39304D102 60 1,300 SH   DFND 0 0 1,300 0
GREEN PLAINS INC COM 393222104 1,875 69,262 SH   DFND 0 0 69,262 0
GRITSTONE ONCOLOGY INC COM 39868T105 1,641 174,000 SH   DFND 0 0 174,000 0
GROWGENERATION CORP COM 39986L109 3,309 66,600 SH   DFND 0 0 66,600 0
HAEMONETICS CORP MASS COM 405024100 21,059 189,700 SH   DFND 0 0 189,700 0
HAIN CELESTIAL GROUP INC COM 405217100 3,296 75,607 SH   DFND 0 0 75,607 0
HARLEY DAVIDSON INC COM 412822108 2,916 72,722 SH   DFND 0 0 72,722 0
HARTFORD FINL SVCS GROUP INC COM 416515104 7,581 113,500 SH   DFND 0 0 113,500 0
HAYWARD HLDGS INC COM 421298100 814 48,200 SH   DFND 0 0 48,200 0
HCA HEALTHCARE INC COM 40412C101 16,152 85,760 SH   DFND 0 0 85,760 0
HCI GROUP INC COM 40416E103 13,448 175,056 SH   DFND 0 0 175,056 0
HEALTHCARE SERVICES ACQU COR *W EXP 99/99/999 42227K112 47 75,000 SH   DFND 0 0 75,000 0
HEALTHCARE SERVICES ACQU COR COM CL A 42227K104 968 100,000 SH   DFND 0 0 100,000 0
HERBALIFE NUTRITION LTD COM SHS G4412G101 9,087 204,848 SH   DFND 0 0 204,848 0
HERON THERAPEUTICS INC COM 427746102 1,054 65,000 SH   DFND 0 0 65,000 0
HERSHEY CO COM 427866108 34,354 217,213 SH   DFND 0 0 217,213 0
HESKA CORP COM RESTRC NEW 42805E306 9,544 56,657 SH   DFND 0 0 56,657 0
HEXCEL CORP NEW COM 428291108 5,547 99,045 SH   DFND 0 0 99,045 0
HIBBETT SPORTS INC COM 428567101 1,006 14,600 SH   DFND 0 0 14,600 0
HIGHLAND TRANSCEND PARTNERS *W EXP 99/99/999 G44690124 104 83,333 SH   DFND 0 0 83,333 0
HIGHLAND TRANSCEND PARTNERS COM CL A G44690108 978 100,000 SH   DFND 0 0 100,000 0
HILL ROM HLDGS INC COM 431475102 50,088 453,363 SH   DFND 0 0 453,363 0
HILTON WORLDWIDE HLDGS INC COM 43300A203 42,254 349,434 SH   DFND 0 0 349,434 0
HIMAX TECHNOLOGIES INC SPONSORED ADR 43289P106 928 68,000 SH   DFND 0 0 68,000 0
HOME PT CAPITAL INCORPORATED COM 43734L106 4,858 522,319 SH   DFND 0 0 522,319 0
HONEYWELL INTL INC COM 438516106 5,709 26,300 SH   DFND 0 0 26,300 0
HORIZON ACQUISITION CORP COM CL A G46049105 4,940 500,000 SH   DFND 0 0 500,000 0
HOWMET AEROSPACE INC COM 443201108 33,788 1,051,600 SH   DFND 0 0 1,051,600 0
HUAZHU GROUP LTD SPONSORED ADS 44332N106 10,167 185,200 SH   DFND 0 0 185,200 0
HUB GROUP INC CL A 443320106 4,952 73,600 SH   DFND 0 0 73,600 0
HUBSPOT INC COM 443573100 23,421 51,565 SH   DFND 0 0 51,565 0
HUDSON EXECUTIVE INVT CORP *W EXP 06/21/202 443761119 811 559,250 SH   DFND 0 0 559,250 0
HUDSON EXECUTIVE INVT CORP COM CL A 443761101 3,576 360,435 SH   DFND 0 0 360,435 0
HUMANA INC COM 444859102 57,155 136,327 SH   DFND 0 0 136,327 0
HUMANCO ACQUISITION CORP *W EXP 99/99/999 44487N117 162 125,000 SH   DFND 0 0 125,000 0
HUMANCO ACQUISITION CORP COM CL A 44487N109 1,493 150,000 SH   DFND 0 0 150,000 0
HUNT J B TRANS SVCS INC COM 445658107 3,773 22,448 SH   DFND 0 0 22,448 0
HUNTSMAN CORP COM 447011107 686 23,800 SH   DFND 0 0 23,800 0
HYDROFARM HLDGS GROUP INC COM 44888K209 6,272 103,980 SH   DFND 0 0 103,980 0
IAC INTERACTIVECORP NEW COM 44891N109 1,146 5,300 SH   DFND 0 0 5,300 0
ICHOR HOLDINGS SHS G4740B105 15,855 294,703 SH   DFND 0 0 294,703 0
ICICI BANK LIMITED ADR 45104G104 15,689 978,704 SH   DFND 0 0 978,704 0
ICU MED INC COM 44930G107 37,515 182,610 SH   DFND 0 0 182,610 0
IDACORP INC COM 451107106 3,216 32,171 SH   DFND 0 0 32,171 0
IDEAYA BIOSCIENCES INC COM 45166A102 19,592 833,700 SH   DFND 0 0 833,700 0
IMMUNIC INC COM 4525EP101 6,903 433,047 SH   DFND 0 0 433,047 0
IMMUNOVANT INC COM 45258J102 3,014 187,900 SH   DFND 0 0 187,900 0
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IMPERIAL OIL LTD COM NEW 453038408 11,795 487,000 SH   DFND 0 0 487,000 0
INFRA AND ENERGY ALTRNTIVE I COM 45686J104 8,203 503,249 SH   DFND 0 0 503,249 0
INMODE LTD SHS M5425M103 11,036 152,500 SH   DFND 0 0 152,500 0
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INOGEN INC COM 45780L104 2,552 48,600 SH   DFND 0 0 48,600 0
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INTEGRA LIFESCIENCES HLDGS C COM NEW 457985208 3,135 45,377 SH   DFND 0 0 45,377 0
INTELLIA THERAPEUTICS INC COM 45826J105 14,478 180,400 SH   DFND 0 0 180,400 0
INTERCONTINENTAL EXCHANGE IN COM 45866F104 27,194 243,500 SH   DFND 0 0 243,500 0
INTERNATIONAL FLAVORS&FRAGRA COM 459506101 27,414 196,358 SH   DFND 0 0 196,358 0
INTUIT COM 461202103 17,123 44,700 SH   DFND 0 0 44,700 0
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IQIYI INC SPONSORED ADS 46267X108 62,343 3,751,100 SH   DFND 0 0 3,751,100 0
IQIYI INC SPONSORED ADS 46267X108 3,490 210,000 SH Call DFND 0 0 210,000 0
ISHARES INC MSCI MEXICO ETF 464286822 219 5,000 SH   DFND 0 0 5,000 0
ISHARES INC MSCI STH KOR ETF 464286772 897 10,000 SH   DFND 0 0 10,000 0
ISHARES SILVER TR ISHARES 46428Q109 681 30,000 SH   DFND 0 0 30,000 0
ISHARES TR CHINA LG-CAP ETF 464287184 29,163 625,000 SH Call DFND 0 0 625,000 0
ISHARES TR ISHS 1-5YR INVS 464288646 24,952 456,327 SH   DFND 0 0 456,327 0
ISHARES TR MSCI EMG MKT ETF 464287234 2,667 50,000 SH Call DFND 0 0 50,000 0
ISHARES TR US HOME CONS ETF 464288752 10,180 150,000 SH Call DFND 0 0 150,000 0
ITAMAR MED LTD SPONSORED ADS 465437101 2,402 100,300 SH   DFND 0 0 100,300 0
ITRON INC COM 465741106 8,200 92,500 SH   DFND 0 0 92,500 0
JABIL INC COM 466313103 167,230 3,206,100 SH   DFND 0 0 3,206,100 0
JACK CREEK INVESTMENT CORP UNIT 10/01/2023 G4989X107 991 100,000 SH   DFND 0 0 100,000 0
JAWS ACQUISITION CORP SHS G50744104 2,650 200,000 SH   DFND 0 0 200,000 0
JD.COM INC SPON ADR CL A 47215P106 86,381 1,024,325 SH   DFND 0 0 1,024,325 0
JETBLUE AWYS CORP COM 477143101 555 27,290 SH   DFND 0 0 27,290 0
JOHNSON & JOHNSON COM 478160104 16,435 100,000 SH Call DFND 0 0 100,000 0
JOHNSON CTLS INTL PLC SHS G51502105 34,616 580,128 SH   DFND 0 0 580,128 0
JOYY INC ADS REPSTG COM A 46591M109 2,334 24,900 SH   DFND 0 0 24,900 0
JUMIA TECHNOLOGIES AG SPONSORED ADS 48138M105 2,486 70,100 SH   DFND 0 0 70,100 0
KADMON HLDGS INC COM 48283N106 45,844 11,785,115 SH   DFND 0 0 11,785,115 0
KANSAS CITY SOUTHERN COM NEW 485170302 29,224 110,731 SH   DFND 0 0 110,731 0
KB HOME COM 48666K109 15,071 323,899 SH   DFND 0 0 323,899 0
KENSINGTON CAPITAL ACQUISITI UNIT 99/99/9999 49006L203 1,026 100,000 SH   DFND 0 0 100,000 0
KEROS THERAPEUTICS INC COM 492327101 13,736 223,162 SH   DFND 0 0 223,162 0
KEURIG DR PEPPER INC COM 49271V100 7,673 223,253 SH   DFND 0 0 223,253 0
KINDRED BIOSCIENCES INC COM 494577109 19,135 3,850,200 SH   DFND 0 0 3,850,200 0
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KOHLS CORP COM 500255104 29,140 488,845 SH   DFND 0 0 488,845 0
KOHLS CORP COM 500255104 3,577 60,000 SH Call DFND 0 0 60,000 0
KONTOOR BRANDS INC COM 50050N103 21,557 444,195 SH   DFND 0 0 444,195 0
KRYSTAL BIOTECH INC COM 501147102 13,020 169,000 SH   DFND 0 0 169,000 0
L BRANDS INC COM 501797104 113,753 1,838,876 SH   DFND 0 0 1,838,876 0
LABORATORY CORP AMER HLDGS COM NEW 50540R409 26,727 104,800 SH   DFND 0 0 104,800 0
LAMAR ADVERTISING CO NEW CL A 512816109 13,221 140,766 SH   DFND 0 0 140,766 0
LAMB WESTON HLDGS INC COM 513272104 34,224 441,710 SH   DFND 0 0 441,710 0
LANDS END INC NEW COM 51509F105 340 13,700 SH   DFND 0 0 13,700 0
LARIMAR THERAPEUTICS INC COM 517125100 252 17,260 SH   DFND 0 0 17,260 0
LAS VEGAS SANDS CORP COM 517834107 62,169 1,023,183 SH   DFND 0 0 1,023,183 0
LAS VEGAS SANDS CORP COM 517834107 85,368 1,405,000 SH Call DFND 0 0 1,405,000 0
LAUDER ESTEE COS INC CL A 518439104 73,220 251,746 SH   DFND 0 0 251,746 0
LAVA THERAPEUTICS NV SHS N51517105 84 5,561 SH   DFND 0 0 5,561 0
LEGEND BIOTECH CORP SPONSORED ADS 52490G102 47,570 1,639,200 SH   DFND 0 0 1,639,200 0
LENNAR CORP CL A 526057104 2,145 21,186 SH   DFND 0 0 21,186 0
LENNAR CORP CL A 526057104 10,123 100,000 SH Put DFND 0 0 100,000 0
LENNOX INTL INC COM 526107107 1,142 3,666 SH   DFND 0 0 3,666 0
LESLIES INC COM 527064109 1,183 48,300 SH   DFND 0 0 48,300 0
LIBERTY BROADBAND CORP COM SER C 530307305 1,426 9,500 SH   DFND 0 0 9,500 0
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LIBERTY GLOBAL PLC SHS CL C G5480U120 429 16,800 SH   DFND 0 0 16,800 0
LIBERTY MEDIA ACQUISITION CO UNIT 01/22/2026 53073L203 1,017 95,000 SH   DFND 0 0 95,000 0
LIBERTY MEDIA CORP DEL COM A SIRIUSXM 531229409 943 21,400 SH   DFND 0 0 21,400 0
LIBERTY MEDIA CORP DEL COM C SIRIUSXM 531229607 1,131 25,650 SH   DFND 0 0 25,650 0
LIONS GATE ENTMNT CORP CL A VTG 535919401 1,632 109,183 SH   DFND 0 0 109,183 0
LIVANOVA PLC SHS G5509L101 5,390 73,105 SH   DFND 0 0 73,105 0
LIVE NATION ENTERTAINMENT IN COM 538034109 8,322 98,308 SH   DFND 0 0 98,308 0
LORDSTOWN MOTORS CORP COM CL A 54405Q100 4,815 409,070 SH   DFND 0 0 409,070 0
LORDSTOWN MOTORS CORP COM CL A 54405Q100 4,149 352,500 SH Call DFND 0 0 352,500 0
LOUISIANA PAC CORP COM 546347105 1,808 32,600 SH   DFND 0 0 32,600 0
LPL FINL HLDGS INC COM 50212V100 2,459 17,300 SH   DFND 0 0 17,300 0
LUMINEX CORP DEL COM 55027E102 7,777 243,800 SH   DFND 0 0 243,800 0
LYFT INC CL A COM 55087P104 50,118 793,254 SH   DFND 0 0 793,254 0
LYONDELLBASELL INDUSTRIES N SHS - A - N53745100 4,429 42,566 SH   DFND 0 0 42,566 0
MACOM TECH SOLUTIONS HLDGS I COM 55405Y100 4,177 72,000 SH   DFND 0 0 72,000 0
MACROGENICS INC COM 556099109 18,400 577,700 SH   DFND 0 0 577,700 0
MACYS INC COM 55616P104 4,048 250,000 SH Call DFND 0 0 250,000 0
MADISON SQUARE GRDN SPRT COR CL A 55825T103 5,042 28,098 SH   DFND 0 0 28,098 0
MAGNA INTL INC COM 559222401 8,415 95,583 SH   DFND 0 0 95,583 0
MARATHON OIL CORP COM 565849106 7,269 680,643 SH   DFND 0 0 680,643 0
MARATHON PETE CORP COM 56585A102 35,412 662,035 SH   DFND 0 0 662,035 0
MARKEL CORP COM 570535104 25,940 22,762 SH   DFND 0 0 22,762 0
MARRIOTT VACTINS WORLDWID CO COM 57164Y107 17,791 102,140 SH   DFND 0 0 102,140 0
MARTIN MARIETTA MATLS INC COM 573284106 24,716 73,599 SH   DFND 0 0 73,599 0
MARVELL TECHNOLOGY GROUP LTD ORD G5876H105 8,136 166,100 SH   DFND 0 0 166,100 0
MASONITE INTL CORP COM 575385109 5,762 50,000 SH   DFND 0 0 50,000 0
MASTERCARD INCORPORATED CL A 57636Q104 110,316 309,834 SH   DFND 0 0 309,834 0
MATTEL INC COM 577081102 20,116 1,009,849 SH   DFND 0 0 1,009,849 0
MAXAR TECHNOLOGIES INC COM 57778K105 7,061 186,700 SH   DFND 0 0 186,700 0
MCCORMICK & CO INC COM NON VTG 579780206 7,485 83,953 SH   DFND 0 0 83,953 0
MCDONALDS CORP COM 580135101 12,863 57,389 SH   DFND 0 0 57,389 0
MCKESSON CORP COM 58155Q103 8,899 45,629 SH   DFND 0 0 45,629 0
MEDPACE HLDGS INC COM 58506Q109 18,602 113,390 SH   DFND 0 0 113,390 0
MEDTECH ACQUISITION CORP *W EXP 12/18/202 58507N113 147 133,333 SH   DFND 0 0 133,333 0
MEDTECH ACQUISITION CORP COM CL A 58507N105 1,932 200,000 SH   DFND 0 0 200,000 0
MEDTRONIC PLC SHS G5960L103 51,635 437,100 SH   DFND 0 0 437,100 0
MEI PHARMA INC COM NEW 55279B202 3,945 1,150,200 SH   DFND 0 0 1,150,200 0
MELCO RESORTS AND ENTMNT LTD ADR 585464100 13,286 667,282 SH   DFND 0 0 667,282 0
MERCK & CO. INC COM 58933Y105 121,802 1,580,000 SH   DFND 0 0 1,580,000 0
MERCK & CO. INC COM 58933Y105 38,545 500,000 SH Call DFND 0 0 500,000 0
MERCURY SYS INC COM 589378108 4,091 57,900 SH   DFND 0 0 57,900 0
MEREO BIOPHARMA GROUP PLC ADS 589492107 27,892 8,276,500 SH   DFND 0 0 8,276,500 0
MERSANA THERAPEUTICS INC COM 59045L106 16,877 1,043,100 SH   DFND 0 0 1,043,100 0
METLIFE INC COM 59156R108 1,331 21,900 SH   DFND 0 0 21,900 0
METTLER TOLEDO INTERNATIONAL COM 592688105 16,526 14,300 SH   DFND 0 0 14,300 0
MGM RESORTS INTERNATIONAL COM 552953101 41,131 1,082,667 SH   DFND 0 0 1,082,667 0
MGM RESORTS INTERNATIONAL COM 552953101 7,598 200,000 SH Call DFND 0 0 200,000 0
MICROCHIP TECHNOLOGY INC. COM 595017104 86,352 556,318 SH   DFND 0 0 556,318 0
MICRON TECHNOLOGY INC COM 595112103 185,318 2,100,875 SH   DFND 0 0 2,100,875 0
MICROSOFT CORP COM 594918104 140,532 596,055 SH   DFND 0 0 596,055 0
MINISO GROUP HLDG LTD SPONSORED ADS 66981J102 1,686 70,200 SH   DFND 0 0 70,200 0
MIRATI THERAPEUTICS INC COM 60468T105 45,806 267,400 SH   DFND 0 0 267,400 0
MIRUM PHARMACEUTICALS INC COM 604749101 99 5,000 SH   DFND 0 0 5,000 0
MKS INSTRS INC COM 55306N104 2,044 11,024 SH   DFND 0 0 11,024 0
MODIVCARE INC COM 60783X104 9,524 64,300 SH   DFND 0 0 64,300 0
MOGO INC COM 60800C109 15,833 1,862,700 SH   DFND 0 0 1,862,700 0
MOHAWK INDS INC COM 608190104 29,639 154,120 SH   DFND 0 0 154,120 0
MOLSON COORS BEVERAGE CO CL B 60871R209 5,115 100,000 SH Put DFND 0 0 100,000 0
MONEYGRAM INTL INC COM NEW 60935Y208 6,869 1,045,532 SH   DFND 0 0 1,045,532 0
MONRO INC COM 610236101 10,877 165,300 SH   DFND 0 0 165,300 0
MONSTER BEVERAGE CORP NEW COM 61174X109 34,039 373,687 SH   DFND 0 0 373,687 0
MORGAN STANLEY COM NEW 617446448 33,658 433,400 SH   DFND 0 0 433,400 0
MORPHIC HLDG INC COM 61775R105 26,147 413,200 SH   DFND 0 0 413,200 0
MOTIVE CAPITAL CORP *W EXP 12/31/202 G6293A111 73 83,333 SH   DFND 0 0 83,333 0
MOTIVE CAPITAL CORP SHS CL A G6293A103 980 100,000 SH   DFND 0 0 100,000 0
MOTOROLA SOLUTIONS INC COM NEW 620076307 13,314 70,800 SH   DFND 0 0 70,800 0
MSC INDL DIRECT INC CL A 553530106 4,636 51,400 SH   DFND 0 0 51,400 0
MYOVANT SCIENCES LTD COM G637AM102 790 38,400 SH   DFND 0 0 38,400 0
MYRIAD GENETICS INC COM 62855J104 12,114 397,848 SH   DFND 0 0 397,848 0
NANO X IMAGING LTD ORD SHS M70700105 4,145 100,000 SH Put DFND 0 0 100,000 0
NANOSTRING TECHNOLOGIES INC COM 63009R109 17,510 266,474 SH   DFND 0 0 266,474 0
NATERA INC COM 632307104 74,904 737,682 SH   DFND 0 0 737,682 0
NCINO INC COM 63947U107 814 12,200 SH   DFND 0 0 12,200 0
NCR CORP NEW COM 62886E108 58,941 1,553,129 SH   DFND 0 0 1,553,129 0
NEBULA CARAVEL ACQUISITION C *W EXP 10/01/202 629070111 61 40,000 SH   DFND 0 0 40,000 0
NEOLEUKIN THERAPEUTICS INC COM 64049K104 16,109 1,308,600 SH   DFND 0 0 1,308,600 0
NETFLIX INC COM 64110L106 118,172 226,531 SH   DFND 0 0 226,531 0
NEW ORIENTAL ED & TECHNOLOGY SPON ADR 647581107 1,705 121,800 SH   DFND 0 0 121,800 0
NEW YORK TIMES CO CL A 650111107 20,681 408,545 SH   DFND 0 0 408,545 0
NEXTDECADE CORP COM 65342K105 615 230,200 SH   DFND 0 0 230,200 0
NEXTERA ENERGY INC COM 65339F101 95,151 1,258,439 SH   DFND 0 0 1,258,439 0
NEXTGEN ACQUISITION CORP CL A G65305107 285 28,708 SH   DFND 0 0 28,708 0
NGM BIOPHARMACEUTICALS INC COM 62921N105 63,227 2,175,000 SH   DFND 0 0 2,175,000 0
NICE LTD SPONSORED ADR 653656108 94,577 433,900 SH   DFND 0 0 433,900 0
NIKE INC CL B 654106103 40,101 301,760 SH   DFND 0 0 301,760 0
NIKE INC CL B 654106103 13,289 100,000 SH Call DFND 0 0 100,000 0
NMI HLDGS INC CL A 629209305 1,182 50,000 SH   DFND 0 0 50,000 0
NOKIA CORP SPONSORED ADR 654902204 3,168 800,000 SH Put DFND 0 0 800,000 0
NOMAD FOODS LTD USD ORD SHS G6564A105 10,129 368,852 SH   DFND 0 0 368,852 0
NORDIC AMERICAN TANKERS LIMI COM G65773106 3,352 1,031,400 SH   DFND 0 0 1,031,400 0
NORDSTROM INC COM 655664100 5,223 137,931 SH   DFND 0 0 137,931 0
NORTHERN GENESIS ACQUISITION COMMON STOCK 66516T104 13,964 856,173 SH   DFND 0 0 856,173 0
NORTHERN GENESIS ACQUISITION UNIT 99/99/9999 66516U200 9,974 974,000 SH   DFND 0 0 974,000 0
NORTHERN OIL AND GAS INC MN COM 665531307 843 69,799 SH   DFND 0 0 69,799 0
NORTHERN STAR ACQUISITION CO *W EXP 08/29/202 665742110 75 25,000 SH   DFND 0 0 25,000 0
NOVAVAX INC COM NEW 670002401 15,194 83,800 SH   DFND 0 0 83,800 0
NUANCE COMMUNICATIONS INC COM 67020Y100 9,292 212,935 SH   DFND 0 0 212,935 0
NUTRIEN LTD COM 67077M108 6,914 128,300 SH   DFND 0 0 128,300 0
NXP SEMICONDUCTORS N V COM N6596X109 158,161 785,542 SH   DFND 0 0 785,542 0
OCCIDENTAL PETE CORP COM 674599105 38,571 1,448,956 SH   DFND 0 0 1,448,956 0
OGE ENERGY CORP COM 670837103 6,945 214,607 SH   DFND 0 0 214,607 0
OLD DOMINION FREIGHT LINE IN COM 679580100 20,550 85,481 SH   DFND 0 0 85,481 0
OLEMA PHARMACEUTICALS INC COM 68062P106 3,116 93,900 SH   DFND 0 0 93,900 0
OLIN CORP COM PAR $1 680665205 7,313 192,600 SH   DFND 0 0 192,600 0
OLINK HLDG AB SPONSORED ADS 680710100 2,796 77,670 SH   DFND 0 0 77,670 0
OLO INC CL A 68134L109 1,320 50,000 SH   DFND 0 0 50,000 0
OMNICHANNEL ACQUISITION CORP *W EXP 12/30/202 68218L116 100 125,000 SH   DFND 0 0 125,000 0
OMNICOM GROUP INC COM 681919106 24,177 326,060 SH   DFND 0 0 326,060 0
ON SEMICONDUCTOR CORP COM 682189105 6,033 145,000 SH   DFND 0 0 145,000 0
ONEMAIN HLDGS INC COM 68268W103 43,701 813,500 SH   DFND 0 0 813,500 0
OPEN LENDING CORP COM CL A 68373J104 78,250 2,209,202 SH   DFND 0 0 2,209,202 0
OREILLY AUTOMOTIVE INC COM 67103H107 18,148 35,778 SH   DFND 0 0 35,778 0
ORIC PHARMACEUTICALS INC COM 68622P109 31,498 1,285,647 SH   DFND 0 0 1,285,647 0
ORPHAZYME A S ADS 687305102 1,120 133,541 SH   DFND 0 0 133,541 0
ORTHO CLINICAL DIAGNOSTICS H ORD SHS G6829J107 9,391 486,700 SH   DFND 0 0 486,700 0
ORTHOFIX MED INC COM 68752M108 11,232 259,100 SH   DFND 0 0 259,100 0
ORTHOPEDIATRICS CORP COM 68752L100 1,976 40,534 SH   DFND 0 0 40,534 0
OSHKOSH CORP COM 688239201 6,977 58,800 SH   DFND 0 0 58,800 0
OTIS WORLDWIDE CORP COM 68902V107 81,830 1,195,469 SH   DFND 0 0 1,195,469 0
OTONOMY INC COM 68906L105 905 355,000 SH   DFND 0 0 355,000 0
OUTFRONT MEDIA INC COM 69007J106 17,687 810,236 SH   DFND 0 0 810,236 0
OVERSTOCK COM INC DEL COM 690370101 629 9,500 SH   DFND 0 0 9,500 0
OVINTIV INC COM 69047Q102 16,189 679,633 SH   DFND 0 0 679,633 0
PAGSEGURO DIGITAL LTD COM CL A G68707101 183,437 3,961,924 SH   DFND 0 0 3,961,924 0
PALO ALTO NETWORKS INC COM 697435105 106,350 330,219 SH   DFND 0 0 330,219 0
PARKER-HANNIFIN CORP COM 701094104 5,004 15,865 SH   DFND 0 0 15,865 0
PASSAGE BIO INC COM 702712100 3,884 222,200 SH   DFND 0 0 222,200 0
PATRIA INVESTMENTS LIMITED COM CL A G69451105 42,054 2,414,122 SH   DFND 0 0 2,414,122 0
PAYA HOLDINGS INC COM CL A 70434P103 73,238 6,682,300 SH   DFND 0 0 6,682,300 0
PAYPAL HLDGS INC COM 70450Y103 125,098 515,145 SH   DFND 0 0 515,145 0
PAYSAFE LIMITED ORD G6964L107 19,575 1,450,000 SH   DFND 0 0 1,450,000 0
PELOTON INTERACTIVE INC CL A COM 70614W100 8,995 80,000 SH Put DFND 0 0 80,000 0
PEMBINA PIPELINE CORP COM 706327103 12,217 423,000 SH   DFND 0 0 423,000 0
PENUMBRA INC COM 70975L107 9,254 34,200 SH   DFND 0 0 34,200 0
PEPSICO INC COM 713448108 23,778 168,102 SH   DFND 0 0 168,102 0
PERFORMANCE FOOD GROUP CO COM 71377A103 27,798 482,525 SH   DFND 0 0 482,525 0
PERIDOT ACQUISITION CORP SHS CL A G7008A115 266 25,000 SH   DFND 0 0 25,000 0
PERRIGO CO PLC SHS G97822103 48,475 1,197,791 SH   DFND 0 0 1,197,791 0
PERSHING SQUARE TONTINE HLDG *W EXP 07/24/202 71531R117 86 10,555 SH   DFND 0 0 10,555 0
PERSHING SQUARE TONTINE HLDG COM CL A 71531R109 2,281 95,000 SH   DFND 0 0 95,000 0
PETROLEO BRASILEIRO SA PETRO SPONSORED ADR 71654V408 1,356 159,900 SH   DFND 0 0 159,900 0
PETROLEO BRASILEIRO SA PETRO SPONSORED ADR 71654V408 5,512 650,000 SH Call DFND 0 0 650,000 0
PG&E CORP COM 69331C108 42,523 3,631,345 SH   DFND 0 0 3,631,345 0
PHILIP MORRIS INTL INC COM 718172109 25,632 288,848 SH   DFND 0 0 288,848 0
PILGRIMS PRIDE CORP COM 72147K108 9,226 387,800 SH   DFND 0 0 387,800 0
PINTEREST INC CL A 72352L106 54,154 731,511 SH   DFND 0 0 731,511 0
PINTEREST INC CL A 72352L106 2,221 30,000 SH Call DFND 0 0 30,000 0
PIONEER MERGER CORP UNIT 99/99/9999 G7S24C129 4,995 500,000 SH   DFND 0 0 500,000 0
PLAINS GP HLDGS L P LTD PARTNR INT A 72651A207 3,082 327,900 SH   DFND 0 0 327,900 0
POLARIS INC COM 731068102 8,994 67,372 SH   DFND 0 0 67,372 0
POPULAR INC COM NEW 733174700 4,001 56,900 SH   DFND 0 0 56,900 0
POPULATION HEALTH INVS CO IN *W EXP 10/01/202 G71716115 53 50,000 SH   DFND 0 0 50,000 0
PORTLAND GEN ELEC CO COM NEW 736508847 9,415 198,336 SH   DFND 0 0 198,336 0
POST HLDGS INC COM 737446104 16,927 160,114 SH   DFND 0 0 160,114 0
PRAXIS PRECISION MEDICINES I COM 74006W108 4,488 136,995 SH   DFND 0 0 136,995 0
PRIMORIS SVCS CORP COM 74164F103 1,875 56,592 SH   DFND 0 0 56,592 0
PROCTER AND GAMBLE CO COM 742718109 43,921 324,310 SH   DFND 0 0 324,310 0
PROGRESS ACQUISITION CORP UNIT 12/25/2025 74327P204 432 43,900 SH   DFND 0 0 43,900 0
PROMETHEUS BIOSCIENCES INC COM 74349U108 14,608 800,000 SH   DFND 0 0 800,000 0
PROOFPOINT INC COM 743424103 17,677 140,530 SH   DFND 0 0 140,530 0
PROQR THRAPEUTICS N V SHS EURO N71542109 10,059 1,521,800 SH   DFND 0 0 1,521,800 0
PROSPECTOR CAPITAL CORP UNIT 01/01/2030 G7273A121 2,619 260,063 SH   DFND 0 0 260,063 0
PROTAGONIST THERAPEUTICS INC COM 74366E102 24,406 942,300 SH   DFND 0 0 942,300 0
PTC THERAPEUTICS INC COM 69366J200 3,007 63,509 SH   DFND 0 0 63,509 0
PUBLIC STORAGE COM 74460D109 3,751 15,200 SH   DFND 0 0 15,200 0
PULMONX CORP COM 745848101 14,926 326,313 SH   DFND 0 0 326,313 0
PULTE GROUP INC COM 745867101 7,866 150,000 SH Put DFND 0 0 150,000 0
PURECYCLE TECHNOLOGIES INC COM 74623V103 3,436 134,748 SH   DFND 0 0 134,748 0
PVH CORPORATION COM 693656100 59,814 565,880 SH   DFND 0 0 565,880 0
PVH CORPORATION COM 693656100 5,549 52,500 SH Put DFND 0 0 52,500 0
Q2 HLDGS INC COM 74736L109 541 5,400 SH   DFND 0 0 5,400 0
QELL ACQUISITION CORP *W EXP 10/01/202 G7307X113 172 100,000 SH   DFND 0 0 100,000 0
QELL ACQUISITION CORP CL A G7307X105 509 50,000 SH   DFND 0 0 50,000 0
QTS RLTY TR INC COM CL A 74736A103 11,690 188,427 SH   DFND 0 0 188,427 0
QUANTA SVCS INC COM 74762E102 3,528 40,100 SH   DFND 0 0 40,100 0
QUANTUMSCAPE CORP COM CL A 74767V109 793 17,715 SH   DFND 0 0 17,715 0
QURATE RETAIL INC COM SER A 74915M100 7,942 675,300 SH   DFND 0 0 675,300 0
R1 RCM INC COM 749397105 9,749 395,027 SH   DFND 0 0 395,027 0
RACKSPACE TECHNOLOGY INC COM 750102105 40,279 1,693,800 SH   DFND 0 0 1,693,800 0
RADNET INC COM 750491102 7,941 365,100 SH   DFND 0 0 365,100 0
RALPH LAUREN CORP CL A 751212101 6,679 54,232 SH   DFND 0 0 54,232 0
RAYMOND JAMES FINL INC COM 754730109 4,081 33,300 SH   DFND 0 0 33,300 0
RAYTHEON TECHNOLOGIES CORP COM 75513E101 121,527 1,572,759 SH   DFND 0 0 1,572,759 0
REATA PHARMACEUTICALS INC CL A 75615P103 5,862 58,800 SH   DFND 0 0 58,800 0
REDBALL ACQUISITION CORP *W EXP 08/17/202 G7417R113 45 33,333 SH   DFND 0 0 33,333 0
REDBALL ACQUISITION CORP COM CL A G7417R105 995 99,999 SH   DFND 0 0 99,999 0
REGENXBIO INC COM 75901B107 30,914 906,300 SH   DFND 0 0 906,300 0
REGULUS THERAPEUTICS INC COM NEW 75915K200 5,016 3,215,436 SH   DFND 0 0 3,215,436 0
REINVENT TECHNOLOGY PARTNERS *W EXP 09/16/202 G74847115 19 12,000 SH   DFND 0 0 12,000 0
REINVENT TECHNOLOGY PARTNERS UNIT 03/12/2026 G7484L114 703 70,000 SH   DFND 0 0 70,000 0
RELMADA THERAPEUTICS INC COM 75955J402 6,074 172,500 SH   DFND 0 0 172,500 0
RENEWABLE ENERGY GROUP INC COM NEW 75972A301 28,728 435,002 SH   DFND 0 0 435,002 0
REPARE THERAPEUTICS INC COM 760273102 3,069 100,000 SH   DFND 0 0 100,000 0
REPAY HLDGS CORP COM CL A 76029L100 1,132 48,200 SH   DFND 0 0 48,200 0
REPLIGEN CORP COM 759916109 66,404 341,567 SH   DFND 0 0 341,567 0
REPLIMUNE GROUP INC COM 76029N106 18,772 615,278 SH   DFND 0 0 615,278 0
REPUBLIC SVCS INC COM 760759100 8,256 83,096 SH   DFND 0 0 83,096 0
REVANCE THERAPEUTICS INC COM 761330109 7,502 268,400 SH   DFND 0 0 268,400 0
REVOLVE GROUP INC CL A 76156B107 20,859 464,266 SH   DFND 0 0 464,266 0
REXNORD CORP COM 76169B102 25,840 548,726 SH   DFND 0 0 548,726 0
RIBBIT LEAP LTD *W EXP 09/09/202 G7552B113 120 40,000 SH   DFND 0 0 40,000 0
RIBBIT LEAP LTD SHS CL A G7552B105 1,650 150,000 SH   DFND 0 0 150,000 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 3,970 1,160,900 SH   DFND 0 0 1,160,900 0
RINGCENTRAL INC CL A 76680R206 35,311 118,541 SH   DFND 0 0 118,541 0
RITE AID CORP COM 767754872 9,373 458,123 SH   DFND 0 0 458,123 0
RLX TECHNOLOGY INC SPONSORED ADS 74969N103 1,236 119,300 SH   DFND 0 0 119,300 0
RMG ACQUISITION CORP II CL A SHS G76083107 2,756 275,000 SH   DFND 0 0 275,000 0
RMG ACQUISITION CORP II UNIT 12/09/2025 G76083115 3,691 351,871 SH   DFND 0 0 351,871 0
ROBLOX CORP CL A 771049103 3,056 47,133 SH   DFND 0 0 47,133 0
RODGERS SILICON VALLEY AQ CO COM 774873103 1,586 119,125 SH   DFND 0 0 119,125 0
ROKU INC COM CL A 77543R102 2,352 7,219 SH   DFND 0 0 7,219 0
ROPER TECHNOLOGIES INC COM 776696106 17,445 43,252 SH   DFND 0 0 43,252 0
ROSS STORES INC COM 778296103 38,846 323,961 SH   DFND 0 0 323,961 0
ROYAL CARIBBEAN GROUP COM V7780T103 20,021 233,859 SH   DFND 0 0 233,859 0
ROYAL DUTCH SHELL PLC SPON ADR B 780259107 24,974 678,100 SH   DFND 0 0 678,100 0
ROYAL DUTCH SHELL PLC SPONS ADR A 780259206 14,229 362,891 SH   DFND 0 0 362,891 0
RYMAN HOSPITALITY PPTYS INC COM 78377T107 4,341 56,000 SH   DFND 0 0 56,000 0
SAGE THERAPEUTICS INC COM 78667J108 24,977 333,700 SH   DFND 0 0 333,700 0
SAILPOINT TECHNOLOGIES HLDGS COM 78781P105 19,648 388,000 SH   DFND 0 0 388,000 0
SALESFORCE COM INC COM 79466L302 100,808 475,800 SH   DFND 0 0 475,800 0
SALLY BEAUTY HLDGS INC COM 79546E104 8,054 400,100 SH   DFND 0 0 400,100 0
SANDERSON FARMS INC COM 800013104 4,938 31,700 SH   DFND 0 0 31,700 0
SANGAMO THERAPEUTICS INC COM 800677106 8,523 680,200 SH   DFND 0 0 680,200 0
SANOFI SPONSORED ADR 80105N105 52,299 1,057,400 SH   DFND 0 0 1,057,400 0
SAREPTA THERAPEUTICS INC COM 803607100 10,359 138,986 SH   DFND 0 0 138,986 0
SATSUMA PHARMACEUTICALS INC COM 80405P107 2,965 528,169 SH   DFND 0 0 528,169 0
SCHLUMBERGER LTD COM 806857108 42,259 1,554,218 SH   DFND 0 0 1,554,218 0
SCION TECH GROWTH I *W EXP 11/01/202 G31067112 31 33,333 SH   DFND 0 0 33,333 0
SCION TECH GROWTH I CL A SHS G31067104 490 50,000 SH   DFND 0 0 50,000 0
SCORPIO TANKERS INC SHS Y7542C130 3,917 212,200 SH   DFND 0 0 212,200 0
SCOTTS MIRACLE-GRO CO CL A 810186106 12,548 51,221 SH   DFND 0 0 51,221 0
SCRIPPS E W CO OHIO CL A NEW 811054402 1,220 63,300 SH   DFND 0 0 63,300 0
SEA LTD SPONSORD ADS 81141R100 72,600 325,226 SH   DFND 0 0 325,226 0
SEAGEN INC COM 81181C104 99,220 714,536 SH   DFND 0 0 714,536 0
SEAPORT GLOBAL ACQUISITN COR *W EXP 12/15/202 812227114 62 112,500 SH   DFND 0 0 112,500 0
SEAWORLD ENTMT INC COM 81282V100 50,234 1,011,345 SH   DFND 0 0 1,011,345 0
SELECT MED HLDGS CORP COM 81619Q105 62,520 1,833,423 SH   DFND 0 0 1,833,423 0
SELECT SECTOR SPDR TR ENERGY 81369Y506 24,530 500,000 SH   DFND 0 0 500,000 0
SELECT SECTOR SPDR TR SBI INT-FINL 81369Y605 4,699 138,000 SH   DFND 0 0 138,000 0
SELECT SECTOR SPDR TR SBI INT-FINL 81369Y605 3,405 100,000 SH Call DFND 0 0 100,000 0
SELECT SECTOR SPDR TR SBI INT-UTILS 81369Y886 3,265 50,987 SH   DFND 0 0 50,987 0
SELECTQUOTE INC COM 816307300 15,388 521,461 SH   DFND 0 0 521,461 0
SEMPRA ENERGY COM 816851109 41,312 311,600 SH   DFND 0 0 311,600 0
SEMRUSH HLDGS INC CL A COM 81686C104 596 50,000 SH   DFND 0 0 50,000 0
SERES THERAPEUTICS INC COM 81750R102 20,068 974,671 SH   DFND 0 0 974,671 0
SERVICENOW INC COM 81762P102 5,221 10,439 SH   DFND 0 0 10,439 0
SEVEN OAKS ACQUISITION CORP *W EXP 12/22/202 81787X114 46 50,000 SH   DFND 0 0 50,000 0
SHIFT4 PMTS INC CL A 82452J109 558 6,800 SH   DFND 0 0 6,800 0
SHOCKWAVE MED INC COM 82489T104 24,736 189,900 SH   DFND 0 0 189,900 0
SHOE CARNIVAL INC COM 824889109 248 4,000 SH   DFND 0 0 4,000 0
SHOPIFY INC CL A 82509L107 15,482 13,992 SH   DFND 0 0 13,992 0
SIBANYE STILLWATER LTD SPONSORED ADR 82575P107 11,780 659,600 SH   DFND 0 0 659,600 0
SIGNATURE BK NEW YORK N Y COM 82669G104 99,661 440,784 SH   DFND 0 0 440,784 0
SIGNET JEWELERS LIMITED SHS G81276100 20,073 346,200 SH   DFND 0 0 346,200 0
SILICON MOTION TECHNOLOGY CO SPONSORED ADR 82706C108 15,170 255,438 SH   DFND 0 0 255,438 0
SILVER SPIKE ACQUISITION COR CL A SHS G8136L106 242 13,207 SH   DFND 0 0 13,207 0
SILVERBACK THERAPEUTICS INC COM 82835W108 12,548 287,600 SH   DFND 0 0 287,600 0
SILVERGATE CAP CORP CL A 82837P408 12,026 84,591 SH   DFND 0 0 84,591 0
SIMON PROPERTY GRP ACQ HOLDI UNIT 99/99/9999 82880R202 503 50,000 SH   DFND 0 0 50,000 0
SIMPLY GOOD FOODS CO COM 82900L102 614 20,200 SH   DFND 0 0 20,200 0
SIX FLAGS ENTMT CORP NEW COM 83001A102 14,476 311,521 SH   DFND 0 0 311,521 0
SLM CORP COM 78442P106 1,481 82,400 SH   DFND 0 0 82,400 0
SM ENERGY CO COM 78454L100 1,804 110,200 SH   DFND 0 0 110,200 0
SMITH MICRO SOFTWARE INC COM NEW 832154207 275 50,000 SH   DFND 0 0 50,000 0
SMUCKER J M CO COM NEW 832696405 22,750 179,803 SH   DFND 0 0 179,803 0
SNOWFLAKE INC CL A 833445109 34,530 150,600 SH   DFND 0 0 150,600 0
SOARING EAGLE ACQUISITION CO UNIT 02/23/2026 G8354H100 10,120 1,000,000 SH   DFND 0 0 1,000,000 0
SOTERA HEALTH CO COM 83601L102 44,761 1,793,324 SH   DFND 0 0 1,793,324 0
SOUTH JERSEY INDS INC COM 838518108 45,252 2,004,060 SH   DFND 0 0 2,004,060 0
SPARTAN ACQUISITION CORP II COM 846775104 2,858 273,278 SH   DFND 0 0 273,278 0
SPDR GOLD TR GOLD SHS 78463V107 2,559 16,000 SH   DFND 0 0 16,000 0
SPDR S&P 500 ETF TR TR UNIT 78462F103 8,838 22,300 SH   DFND 0 0 22,300 0
SPDR S&P 500 ETF TR TR UNIT 78462F103 919,486 2,320,000 SH Put DFND 0 0 2,320,000 0
SPDR SER TR PORTFOLIO INTRMD 78464A375 36,064 994,860 SH   DFND 0 0 994,860 0
SPDR SER TR S&P BIOTECH 78464A870 88,173 650,000 SH Put DFND 0 0 650,000 0
SPDR SER TR S&P HOMEBUILD 78464A888 2,463 35,000 SH   DFND 0 0 35,000 0
SPDR SER TR S&P OILGAS EXP 78468R556 12,201 150,000 SH Call DFND 0 0 150,000 0
SPIRIT AEROSYSTEMS HLDGS INC COM CL A 848574109 31,141 640,098 SH   DFND 0 0 640,098 0
SPLUNK INC COM 848637104 39,384 290,703 SH   DFND 0 0 290,703 0
SPORTS ENTERTAINMENT ACQU CO *W EXP 10/30/202 84918M114 138 125,000 SH   DFND 0 0 125,000 0
SPORTS ENTERTAINMENT ACQU CO COM CL A 84918M106 733 75,000 SH   DFND 0 0 75,000 0
SQUARE INC CL A 852234103 80,739 355,600 SH   DFND 0 0 355,600 0
STARBUCKS CORP COM 855244109 9,365 85,709 SH   DFND 0 0 85,709 0
STEEL DYNAMICS INC COM 858119100 1,579 31,100 SH   DFND 0 0 31,100 0
STELLANTIS N.V SHS N82405106 6,969 391,717 SH   DFND 0 0 391,717 0
STERIS PLC SHS USD G8473T100 14,291 75,028 SH   DFND 0 0 75,028 0
STITCH FIX INC COM CL A 860897107 11,616 234,479 SH   DFND 0 0 234,479 0
STITCH FIX INC COM CL A 860897107 8,670 175,000 SH Call DFND 0 0 175,000 0
STMICROELECTRONICS N V NY REGISTRY 861012102 55,817 1,456,224 SH   DFND 0 0 1,456,224 0
STONECO LTD COM CL A G85158106 6,697 109,400 SH   DFND 0 0 109,400 0
SUMMIT MATLS INC CL A 86614U100 4,763 170,000 SH   DFND 0 0 170,000 0
SUNCOR ENERGY INC NEW COM 867224107 49,482 2,367,466 SH   DFND 0 0 2,367,466 0
SUNNOVA ENERGY INTL INC. COM 86745K104 30,752 753,351 SH   DFND 0 0 753,351 0
SUNRUN INC COM 86771W105 28,966 478,935 SH   DFND 0 0 478,935 0
SUNRUN INC COM 86771W105 6,048 100,000 SH Call DFND 0 0 100,000 0
SUPERNOVA PARTNERS ACQUISITI *W EXP 10/16/202 86846V116 247 133,333 SH   DFND 0 0 133,333 0
SUPERNOVA PARTNERS ACQUISITI COM CL A 86846V108 2,158 213,472 SH   DFND 0 0 213,472 0
SUPERNOVA PARTNERS ACQUISITI COM CL A 86846V108 376 37,200 SH Call DFND 0 0 37,200 0
SUPERNOVA PARTNERS ACQUISTN UNIT 99/99/9999 G8T86C113 2,510 250,000 SH   DFND 0 0 250,000 0
SURFACE ONCOLOGY INC COM 86877M209 946 121,250 SH   DFND 0 0 121,250 0
SUSTAINABLE OPPORTNTS ACQ CO ORD SHS A G8598Y109 1,490 150,000 SH   DFND 0 0 150,000 0
SUTRO BIOPHARMA INC COM 869367102 21,809 958,200 SH   DFND 0 0 958,200 0
SVB FINANCIAL GROUP COM 78486Q101 2,047 4,147 SH   DFND 0 0 4,147 0
SWITCH INC CL A 87105L104 1,348 82,900 SH   DFND 0 0 82,900 0
SYNCHRONY FINANCIAL COM 87165B103 46,751 1,149,800 SH   DFND 0 0 1,149,800 0
SYNDAX PHARMACEUTICALS INC COM 87164F105 21,170 946,800 SH   DFND 0 0 946,800 0
SYNEOS HEALTH INC CL A 87166B102 3,489 46,001 SH   DFND 0 0 46,001 0
SYSCO CORP COM 871829107 51,950 659,764 SH   DFND 0 0 659,764 0
TABULA RASA HEALTHCARE INC COM 873379101 2,980 64,702 SH   DFND 0 0 64,702 0
TACTILE SYS TECHNOLOGY INC COM 87357P100 1,248 22,900 SH   DFND 0 0 22,900 0
TANDEM DIABETES CARE INC COM NEW 875372203 32,679 370,300 SH   DFND 0 0 370,300 0
TAPESTRY INC COM 876030107 58,645 1,423,077 SH   DFND 0 0 1,423,077 0
TARGA RES CORP COM 87612G101 21,991 692,622 SH   DFND 0 0 692,622 0
TARGET CORP COM 87612E106 43,162 217,913 SH   DFND 0 0 217,913 0
TARO PHARMACEUTICAL INDS LTD SHS M8737E108 1,615 21,900 SH   DFND 0 0 21,900 0
TC ENERGY CORP COM 87807B107 16,474 359,407 SH   DFND 0 0 359,407 0
TECHNIPFMC PLC COM G87110105 12,309 1,594,493 SH   DFND 0 0 1,594,493 0
TECHNIPFMC PLC COM G87110105 3,860 500,000 SH Call DFND 0 0 500,000 0
TEEKAY TANKERS LTD CL A Y8565N300 2,460 177,000 SH   DFND 0 0 177,000 0
TELEDYNE TECHNOLOGIES INC COM 879360105 40,352 97,551 SH   DFND 0 0 97,551 0
TELEFLEX INCORPORATED COM 879369106 59,243 142,595 SH   DFND 0 0 142,595 0
TEMPUR SEALY INTL INC COM 88023U101 28,626 783,000 SH   DFND 0 0 783,000 0
TENARIS S A SPONSORED ADS 88031M109 20,670 910,981 SH   DFND 0 0 910,981 0
TENCENT MUSIC ENTMT GROUP SPON ADS 88034P109 23,092 1,127,000 SH   DFND 0 0 1,127,000 0
TENET HEALTHCARE CORP COM NEW 88033G407 9,807 188,600 SH   DFND 0 0 188,600 0
TERADYNE INC COM 880770102 32,693 268,678 SH   DFND 0 0 268,678 0
TEREX CORP NEW COM 880779103 3,749 81,386 SH   DFND 0 0 81,386 0
TESLA INC COM 88160R101 20,038 30,000 SH Put DFND 0 0 30,000 0
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS 881624209 18,103 1,568,700 SH   DFND 0 0 1,568,700 0
TEXAS ROADHOUSE INC COM 882681109 7,721 80,481 SH   DFND 0 0 80,481 0
THE REALREAL INC COM 88339P101 9,022 398,654 SH   DFND 0 0 398,654 0
THE9 LTD SPON ADS NEW 88337K302 1,931 61,900 SH   DFND 0 0 61,900 0
THERAPEUTICS ACQUISITION COR COM CL A 88339T103 3,941 375,000 SH   DFND 0 0 375,000 0
THERMO FISHER SCIENTIFIC INC COM 883556102 9,107 19,955 SH   DFND 0 0 19,955 0
TILRAY INC COM CL 2 88688T100 1,652 72,700 SH   DFND 0 0 72,700 0
TIM S A SPONSORED ADR 88706T108 4,293 378,256 SH   DFND 0 0 378,256 0
TIVITY HEALTH INC COM 88870R102 12,581 563,643 SH   DFND 0 0 563,643 0
TJX COS INC NEW COM 872540109 25,032 378,419 SH   DFND 0 0 378,419 0
T-MOBILE US INC COM 872590104 79,409 633,800 SH   DFND 0 0 633,800 0
TORTOISE ACQUISITION CORP II COM CL A G89554102 3,285 300,000 SH   DFND 0 0 300,000 0
TPG PACE BEN FIN CORP CL A COM G8990D125 2,539 129,658 SH   DFND 0 0 129,658 0
TRADEWEB MKTS INC CL A 892672106 7,030 95,000 SH   DFND 0 0 95,000 0
TRANSALTA CORP COM 89346D107 10,513 1,110,400 SH   DFND 0 0 1,110,400 0
TRANSDIGM GROUP INC COM 893641100 110,431 187,833 SH   DFND 0 0 187,833 0
TRANSLATE BIO INC COM 89374L104 2,488 150,900 SH   DFND 0 0 150,900 0
TRAVEL PLUS LEISURE CO COM 894164102 30,488 498,500 SH   DFND 0 0 498,500 0
TRAVERE THERAPEUTICS INC COM 89422G107 40,155 1,608,126 SH   DFND 0 0 1,608,126 0
TREBIA ACQUISITION CORP COM CL A G9027T109 4,382 440,000 SH   DFND 0 0 440,000 0
TREX CO INC COM 89531P105 15,058 164,500 SH   DFND 0 0 164,500 0
TRICIDA INC COM 89610F101 14,042 2,654,361 SH   DFND 0 0 2,654,361 0
TRIPADVISOR INC COM 896945201 53,091 986,999 SH   DFND 0 0 986,999 0
TRITERRAS INC *W EXP 11/10/202 G9103H110 2,316 1,403,501 SH   DFND 0 0 1,403,501 0
TRITERRAS INC SHS CL A G9103H102 295 40,711 SH   DFND 0 0 40,711 0
TRITON INTL LTD CL A G9078F107 1,518 27,600 SH   DFND 0 0 27,600 0
TRIVAGO N V SPON ADS A SHS 89686D105 501 116,401 SH   DFND 0 0 116,401 0
TRONOX HOLDINGS PLC SHS G9087Q102 5,458 298,242 SH   DFND 0 0 298,242 0
TWC TECH HLDGS II CORP COM 90117G105 13,441 1,366,000 SH   DFND 0 0 1,366,000 0
TWILIO INC CL A 90138F102 19,900 58,400 SH   DFND 0 0 58,400 0
TWITTER INC COM 90184L102 226,653 3,562,053 SH   DFND 0 0 3,562,053 0
TWITTER INC COM 90184L102 3,182 50,000 SH Call DFND 0 0 50,000 0
UBER TECHNOLOGIES INC COM 90353T100 467,694 8,579,975 SH   DFND 0 0 8,579,975 0
UBER TECHNOLOGIES INC COM 90353T100 49,059 900,000 SH Call DFND 0 0 900,000 0
ULTA BEAUTY INC COM 90384S303 31,362 101,438 SH   DFND 0 0 101,438 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 13,618 119,600 SH   DFND 0 0 119,600 0
UNDER ARMOUR INC CL A 904311107 9,108 411,010 SH   DFND 0 0 411,010 0
UNDER ARMOUR INC CL C 904311206 2,904 157,300 SH   DFND 0 0 157,300 0
UNIQURE NV SHS N90064101 64,340 1,909,763 SH   DFND 0 0 1,909,763 0
UNIVERSAL HLTH SVCS INC CL B 913903100 8,889 66,639 SH   DFND 0 0 66,639 0
UNUM GROUP COM 91529Y106 6,571 236,100 SH   DFND 0 0 236,100 0
UNUM THERAPEUTICS INC COM 19240Q201 5,369 611,500 SH   DFND 0 0 611,500 0
US FOODS HLDG CORP COM 912008109 59,955 1,572,808 SH   DFND 0 0 1,572,808 0
USHG ACQUISITION CORP UNIT 99/99/9999 91748P209 3,518 350,000 SH   DFND 0 0 350,000 0
V F CORP COM 918204108 103,870 1,299,680 SH   DFND 0 0 1,299,680 0
VALE S A SPONSORED ADS 91912E105 4,729 272,079 SH   DFND 0 0 272,079 0
VALERO ENERGY CORP COM 91913Y100 32,335 451,600 SH   DFND 0 0 451,600 0
VANECK VECTORS ETF TR OIL SVCS ETF 92189H607 1,242 6,500 SH Call DFND 0 0 6,500 0
VANECK VECTORS ETF TR RUSSIA ETF 92189F403 516 20,000 SH   DFND 0 0 20,000 0
VANGUARD SCOTTSDALE FDS SHRT TRM CORP BD 92206C409 15,237 184,690 SH   DFND 0 0 184,690 0
VAREX IMAGING CORP COM 92214X106 7,918 386,442 SH   DFND 0 0 386,442 0
VERINT SYS INC COM 92343X100 205 4,500 SH   DFND 0 0 4,500 0
VERTEX PHARMACEUTICALS INC COM 92532F100 142,681 663,973 SH   DFND 0 0 663,973 0
VESPER HEALTHCARE ACQSTN COR *W EXP 09/30/202 92538T112 2,208 1,061,400 SH   DFND 0 0 1,061,400 0
VESPER HEALTHCARE ACQSTN COR COM CL A 92538T104 9,180 850,000 SH   DFND 0 0 850,000 0
VIA OPTRONICS AG SPONSORED ADS 91823Y109 1,391 107,700 SH   DFND 0 0 107,700 0
VIACOMCBS INC CL B 92556H206 320 7,100 SH Put DFND 0 0 7,100 0
VIATRIS INC COM 92556V106 5,898 422,200 SH   DFND 0 0 422,200 0
VIEWRAY INC COM 92672L107 4,158 955,861 SH   DFND 0 0 955,861 0
VIPSHOP HOLDINGS LIMITED SPONSORED ADS A 92763W103 95,694 3,204,739 SH   DFND 0 0 3,204,739 0
VIRIDIAN THERAPEUTICS INC COM 92790C104 6,609 395,534 SH   DFND 0 0 395,534 0
VIRTUS INVT PARTNERS INC COM 92828Q109 118 500 SH   DFND 0 0 500 0
VISA INC COM CL A 92826C839 306,247 1,446,403 SH   DFND 0 0 1,446,403 0
VISA INC COM CL A 92826C839 21,173 100,000 SH Call DFND 0 0 100,000 0
VISHAY INTERTECHNOLOGY INC COM 928298108 93,429 3,879,931 SH   DFND 0 0 3,879,931 0
VISTRA CORP COM 92840M102 3,476 196,600 SH   DFND 0 0 196,600 0
VIZIO HLDG CORP CL A COM 92858V101 16,741 690,363 SH   DFND 0 0 690,363 0
VONAGE HLDGS CORP COM 92886T201 428 36,200 SH   DFND 0 0 36,200 0
VOYA FINANCIAL INC COM 929089100 3,386 53,200 SH   DFND 0 0 53,200 0
VPC IMPACT ACQUISITION HLDNG SHS CL A G9441E100 11,224 864,029 SH   DFND 0 0 864,029 0
VROOM INC COM 92918V109 67,160 1,722,484 SH   DFND 0 0 1,722,484 0
VULCAN MATLS CO COM 929160109 29,706 176,036 SH   DFND 0 0 176,036 0
WALMART INC COM 931142103 34,666 255,214 SH   DFND 0 0 255,214 0
WARNER MUSIC GROUP CORP COM CL A 934550203 8,426 245,444 SH   DFND 0 0 245,444 0
WARRIOR MET COAL INC COM 93627C101 1,562 91,200 SH   DFND 0 0 91,200 0
WATERS CORP COM 941848103 66,587 234,322 SH   DFND 0 0 234,322 0
WAVE LIFE SCIENCES LTD SHS Y95308105 4,764 849,109 SH   DFND 0 0 849,109 0
WEBSTER FINL CORP CONN COM 947890109 1,185 21,500 SH   DFND 0 0 21,500 0
WELLS FARGO CO NEW COM 949746101 1,203 30,800 SH   DFND 0 0 30,800 0
WEST FRASER TIMBER CO LTD COM 952845105 12,588 175,000 SH   DFND 0 0 175,000 0
WEST PHARMACEUTICAL SVSC INC COM 955306105 13,203 46,857 SH   DFND 0 0 46,857 0
WESTERN ALLIANCE BANCORP COM 957638109 2,087 22,100 SH   DFND 0 0 22,100 0
WESTERN DIGITAL CORP. COM 958102105 360,964 5,407,700 SH   DFND 0 0 5,407,700 0
WESTLAKE CHEM CORP COM 960413102 5,327 60,000 SH   DFND 0 0 60,000 0
WEX INC COM 96208T104 14,018 67,000 SH   DFND 0 0 67,000 0
WILLIS TOWERS WATSON PLC LTD SHS G96629103 12,784 55,853 SH   DFND 0 0 55,853 0
WIX COM LTD SHS M98068105 3,490 12,500 SH   DFND 0 0 12,500 0
WORKDAY INC CL A 98138H101 43,175 173,791 SH   DFND 0 0 173,791 0
XCEL ENERGY INC COM 98389B100 13,191 198,324 SH   DFND 0 0 198,324 0
XENCOR INC COM 98401F105 5,916 137,400 SH   DFND 0 0 137,400 0
XENON PHARMACEUTICALS INC COM 98420N105 13,622 761,001 SH   DFND 0 0 761,001 0
XPO LOGISTICS INC COM 983793100 12,569 101,940 SH   DFND 0 0 101,940 0
YALLA GROUP LTD ADS 98459U103 4,609 184,300 SH   DFND 0 0 184,300 0
ZENDESK INC COM 98936J101 50,348 379,639 SH   DFND 0 0 379,639 0
ZHIHU INC ADS 98955N108 487 60,000 SH   DFND 0 0 60,000 0
ZILLOW GROUP INC CL C CAP STK 98954M200 16,858 130,034 SH   DFND 0 0 130,034 0
ZOETIS INC CL A 98978V103 48,866 310,300 SH   DFND 0 0 310,300 0
ZOGENIX INC COM NEW 98978L204 6,155 315,300 SH   DFND 0 0 315,300 0
ZUMIEZ INC COM 989817101 116 2,700 SH   DFND 0 0 2,700 0
ZYMEWORKS INC COM 98985W102 5,009 158,600 SH   DFND 0 0 158,600 0
ZYNGA INC CL A 98986T108 3,067 300,425 SH   DFND 0 0 300,425 0