The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABBOTT LABS COM 002824100 BBG001S5N9M6 254,946 2,517 SH   SOLE 1 2,517 0 0
ABBOTT LABS COM 002824100 BBG001S5N9M6 49,724 492 SH   SOLE   492 0 0
ACHILLES THERAPEUTICS PLC SPONSORED ADS 00449L102 BBG00ZHF9WP3 59,367 62,000 SH   SOLE 1 62,000 0 0
ACHILLES THERAPEUTICS PLC SPONSORED ADS 00449L102 BBG00ZHF9WP3 13,048 13,625 SH   SOLE   13,625 0 0
ALX ONCOLOGY HLDGS INC COM 00166B105 BBG00VR8SF73 48,884 10,815 SH   SOLE 1 10,815 0 0
ALX ONCOLOGY HLDGS INC COM 00166B105 BBG00VR8SF73 10,044 2,222 SH   SOLE   2,222 0 0
ANNEXON INC COM 03589W102 BBG007QVDFH1 10,211 2,652 SH   SOLE   2,652 0 0
ANNEXON INC COM 03589W102 BBG007QVDFH1 48,508 12,599 SH   SOLE 1 12,599 0 0
ATHIRA PHARMA INC COM 04746L104 BBG00C77LXM0 9,128 3,650 SH   SOLE   3,650 0 0
ATHIRA PHARMA INC COM 04746L104 BBG00C77LXM0 44,938 17,975 SH   SOLE 1 17,975 0 0
BARCLAYS BANK PLC DJUBS CMDT ETN36 06738C778 BBG001SPJ625 1,068,543 33,826 SH   SOLE   33,826 0 0
BARCLAYS BANK PLC DJUBS CMDT ETN36 06738C778 BBG001SPJ625 366,601 11,605 SH   SOLE 1 11,605 0 0
CODIAK BIOSCIENCES INC COM 192010106 BBG00BGQ1NR9 3,394 19,455 SH   SOLE   19,455 0 0
CODIAK BIOSCIENCES INC COM 192010106 BBG00BGQ1NR9 15,837 90,755 SH   SOLE 1 90,755 0 0
CYTOMX THERAPEUTICS INC COM 23284F105 BBG001V0GS49 6,370 4,218 SH   SOLE   4,218 0 0
CYTOMX THERAPEUTICS INC COM 23284F105 BBG001V0GS49 33,514 22,194 SH   SOLE 1 22,194 0 0
DBX ETF TR XTRACK MSCI EAFE 233051200 BBG001S9Z3V8 6,127,419 174,076 SH   SOLE 1 174,076 0 0
DBX ETF TR XTRACK MSCI EAFE 233051200 BBG001S9Z3V8 1,519,340 43,166 SH   SOLE   43,166 0 0
DEERE & CO COM 244199105 BBG001S5QFF7 450,203 1,090 SH   SOLE 1 1,090 0 0
DESKTOP METAL INC COM CL A 25058X105 BBG00P17H1G9 49,008 21,308 SH   SOLE 1 21,308 0 0
EIGER BIOPHARMACEUTICALS INC COM 28249U105 BBG0026ZCTH6 8,148 9,085 SH   SOLE   9,085 0 0
EIGER BIOPHARMACEUTICALS INC COM 28249U105 BBG0026ZCTH6 38,201 42,594 SH   SOLE 1 42,594 0 0
FIRST TR EXCHANGE-TRADED FD NO AMER ENERGY 33738D101 BBG0034YTRP6 3,607,563 135,469 SH   SOLE 1 135,469 0 0
FIRST TR EXCHANGE-TRADED FD NO AMER ENERGY 33738D101 BBG0034YTRP6 3,042,136 114,237 SH   SOLE   114,237 0 0
GERON CORP COM 374163103 BBG001S6TSX4 10,790 4,972 SH   SOLE   4,972 0 0
GERON CORP COM 374163103 BBG001S6TSX4 49,065 22,610 SH   SOLE 1 22,610 0 0
INCYTE CORP COM 45337C102 BBG001S8Q6N2 44,012 609 SH   SOLE   609 0 0
INCYTE CORP COM 45337C102 BBG001S8Q6N2 210,738 2,916 SH   SOLE 1 2,916 0 0
INVESCO DB COMMDY INDX TRCK UNIT 46138B103 BBG001SNZTS4 316,769 13,343 SH   SOLE 1 13,343 0 0
INVESCO DB MULTI-SECTOR COMM AGRICULTURE FD 46140H106 BBG001SSDLZ6 819,460 40,111 SH   SOLE 1 40,111 0 0
INVESCO EXCH TRADED FD TR II S&P GBL WATER 46138E263 BBG00KJR22S8 43,281 868 SH   SOLE   868 0 0
INVESCO EXCH TRADED FD TR II S&P GBL WATER 46138E263 BBG00KJR22S8 403,667 8,096 SH   SOLE 1 8,096 0 0
INVESCO EXCH TRADED FD TR II SR LN ETF 46138G508 BBG001V0MBC0 367,321 17,659 SH   SOLE 1 17,659 0 0
INVESCO EXCH TRADED FD TR II SR LN ETF 46138G508 BBG001V0MBC0 2,073,375 99,681 SH   SOLE   99,681 0 0
INVESCO EXCH TRD SLF IDX FD INVSCO 30 CORP 46138J460 BBG00X3HYBX8 836,457 50,726 SH   SOLE 1 50,726 0 0
INVESCO EXCHANGE TRADED FD T DWA MOMENTUM 46137V837 BBG001SJ09N0 2,804,726 36,919 SH   SOLE 1 36,919 0 0
ISHARES GOLD TR ISHARES NEW 464285204 BBG001SJK6D5 1,746,786 46,743 SH   SOLE 1 46,743 0 0
ISHARES INC CUR HD MSCI EM 46434G509 BBG0076SN965 780,952 32,485 SH   SOLE 1 32,485 0 0
ISHARES INC CUR HD MSCI EM 46434G509 BBG0076SN965 1,412,827 58,771 SH   SOLE   58,771 0 0
ISHARES INC ESG AWR MSCI EM 46434G863 BBG00D7BDH70 234,998 7,465 SH   SOLE 1 7,465 0 0
ISHARES INC ESG AWR MSCI EM 46434G863 BBG00D7BDH70 26,115 829 SH   SOLE   829 0 0
ISHARES TR 0-5 YR TIPS ETF 46429B747 BBG001TG5H89 328,045 3,306 SH   SOLE 1 3,306 0 0
ISHARES TR 0-5 YR TIPS ETF 46429B747 BBG001TG5H89 1,793,681 18,076 SH   SOLE   18,076 0 0
ISHARES TR 20 YR TR BD ETF 464287432 BBG001S8MLN3 829,498 7,797 SH   SOLE 1 7,797 0 0
ISHARES TR 20 YR TR BD ETF 464287432 BBG001S8MLN3 657 6 SH   SOLE   6 0 0
ISHARES TR 3 7 YR TREAS BD 464288661 BBG001SSD812 1,536,045 13,056 SH   SOLE 1 13,056 0 0
ISHARES TR 3 7 YR TREAS BD 464288661 BBG001SSD812 712,922 6,058 SH   SOLE   6,058 0 0
ISHARES TR 7-10 YR TRSY BD 464287440 BBG001S80936 1,632,869 16,473 SH   SOLE 1 16,473 0 0
ISHARES TR 7-10 YR TRSY BD 464287440 BBG001S80936 902,601 9,103 SH   SOLE   9,103 0 0
ISHARES TR CORE HIGH DV ETF 46429B663 BBG001V0XLT8 4,854,001 47,745 SH   SOLE   47,745 0 0
ISHARES TR CORE HIGH DV ETF 46429B663 BBG001V0XLT8 2,320,479 22,828 SH   SOLE 1 22,828 0 0
ISHARES TR CORE S&P500 ETF 464287200 BBG001SFB7R6 3,076,713 7,486 SH   SOLE   7,486 0 0
ISHARES TR CORE S&P500 ETF 464287200 BBG001SFB7R6 929,608 2,261 SH   SOLE 1 2,261 0 0
ISHARES TR ESG AW MSCI EAFE 46435G516 BBG00D7BBRS7 533,627 7,428 SH   SOLE 1 7,428 0 0
ISHARES TR ESG AW MSCI EAFE 46435G516 BBG00D7BBRS7 19,103,240 265,914 SH   SOLE   265,914 0 0
ISHARES TR FLTG RATE NT ETF 46429B655 BBG001V1QYX1 1,016,386 20,170 SH   SOLE   20,170 0 0
ISHARES TR GLB INFRASTR ETF 464288372 BBG001SYVWT6 3,305,467 69,295 SH   SOLE 1 69,295 0 0
ISHARES TR GLB INFRASTR ETF 464288372 BBG001SYVWT6 4,938,625 103,537 SH   SOLE   103,537 0 0
ISHARES TR GLOBAL REIT ETF 46434V647 BBG006S5D3J3 338,068 14,744 SH   SOLE 1 14,744 0 0
ISHARES TR IBOXX HI YD ETF 464288513 BBG001ST0ZQ7 30,344 402 SH   SOLE   402 0 0
ISHARES TR IBOXX HI YD ETF 464288513 BBG001ST0ZQ7 192,387 2,546 SH   SOLE 1 2,546 0 0
ISHARES TR IBOXX INV CP ETF 464287242 BBG001S60QR6 2,691,990 24,560 SH   SOLE   24,560 0 0
ISHARES TR IBOXX INV CP ETF 464287242 BBG001S60QR6 414,546 3,783 SH   SOLE 1 3,783 0 0
ISHARES TR JPMORGAN USD EMG 464288281 BBG001SQS9Y2 307,750 3,567 SH   SOLE 1 3,567 0 0
ISHARES TR JPMORGAN USD EMG 464288281 BBG001SQS9Y2 2,596,600 30,095 SH   SOLE   30,095 0 0
ISHARES TR MBS ETF 464288588 BBG001SSD8B1 1,606,024 16,955 SH   SOLE   16,955 0 0
ISHARES TR MBS ETF 464288588 BBG001SSD8B1 231,014 2,438 SH   SOLE 1 2,438 0 0
ISHARES TR MSCI EMG MKT ETF 464287234 BBG001SK77D5 305,736 7,748 SH   SOLE 1 7,748 0 0
ISHARES TR MSCI USA MIN VOL 46429B697 BBG0025X2G81 29,529 409 SH   SOLE 1 409 0 0
ISHARES TR MSCI USA MIN VOL 46429B697 BBG0025X2G81 778,743 10,704 SH   SOLE   10,704 0 0
ISHARES TR MSCI USA MMENTM 46432F396 BBG004FPV022 4,766,796 34,284 SH   SOLE 1 34,284 0 0
ISHARES TR MSCI USA MMENTM 46432F396 BBG004FPV022 9,579,346 68,897 SH   SOLE   68,897 0 0
ISHARES TR SHORT TREAS BD 464288679 BBG001SSD803 677,807 6,134 SH   SOLE   6,134 0 0
ISHARES TR SHORT TREAS BD 464288679 BBG001SSD803 649,505 5,878 SH   SOLE 1 5,878 0 0
ISHARES TR TIPS BD ETF 464287176 BBG001SD9RM5 679,414 6,163 SH   SOLE   6,163 0 0
ISHARES TR TIPS BD ETF 464287176 BBG001SD9RM5 1,676,401 15,205 SH   SOLE 1 15,205 0 0
JASPER THERAPEUTICS INC COM 471871103 BBG00QPZNPB4 44,889 24,800 SH   SOLE 1 24,800 0 0
JASPER THERAPEUTICS INC COM 471871103 BBG00QPZNPB4 9,938 5,490 SH   SOLE   5,490 0 0
JPMORGAN CHASE & CO COM 46625H100 BBG001S8CRC3 444,912 3,414 SH   SOLE 1 3,414 0 0
KONINKLIJKE PHILIPS N V NY REGIS SHS NEW 500472303 BBG001S5V5G2 183,500 10,000 SH   SOLE 1 10,000 0 0
KRONOS BIO INC COM 50107A104 BBG00L072932 10,068 6,895 SH   SOLE   6,895 0 0
KRONOS BIO INC COM 50107A104 BBG00L072932 47,304 32,400 SH   SOLE 1 32,400 0 0
MEDTRONIC PLC SHS G5960L103 BBG001S5T2S9 217,882 2,703 SH   SOLE 1 2,703 0 0
MEDTRONIC PLC SHS G5960L103 BBG001S5T2S9 46,801 581 SH   SOLE   581 0 0
MEREO BIOPHARMA GROUP PLC SPON ADS 589492107 BBG00KFWZCX7 49,624 70,200 SH   SOLE 1 70,200 0 0
MEREO BIOPHARMA GROUP PLC SPON ADS 589492107 BBG00KFWZCX7 9,544 13,500 SH   SOLE   13,500 0 0
NKARTA INC COM 65487U108 BBG00JXHS9H6 6,339 1,785 SH   SOLE   1,785 0 0
NKARTA INC COM 65487U108 BBG00JXHS9H6 30,850 8,690 SH   SOLE 1 8,690 0 0
NUSHARES ETF TR NUVEEN ESG LRGVL 67092P300 BBG00FJ5HBJ1 129,152 3,791 SH   SOLE 1 3,791 0 0
NUSHARES ETF TR NUVEEN ESG LRGVL 67092P300 BBG00FJ5HBJ1 6,243,523 183,254 SH   SOLE   183,254 0 0
NVIDIA CORPORATION COM 67066G104 BBG001S5TZJ6 678,438 2,442 SH   SOLE 1 2,442 0 0
ORCHARD THERAPEUTICS PLC SPON ADS NEW 68570P200 BBG00M62QW74 14,053 2,617 SH   SOLE   2,617 0 0
ORCHARD THERAPEUTICS PLC SPON ADS NEW 68570P200 BBG00M62QW74 64,639 12,037 SH   SOLE 1 12,037 0 0
PFIZER INC COM 717081103 BBG001S5V466 45,584 1,116 SH   SOLE   1,116 0 0
PFIZER INC COM 717081103 BBG001S5V466 202,312 4,958 SH   SOLE 1 4,958 0 0
PIMCO ETF TR 15+ YR US TIPS 72201R304 BBG001T5HFW7 7,240,846 117,396 SH   SOLE   117,396 0 0
PIMCO ETF TR 15+ YR US TIPS 72201R304 BBG001T5HFW7 3,989,827 64,686 SH   SOLE 1 64,686 0 0
POSEIDA THERAPEUTICS INC COM 73730P108 BBG00BNTZ9J8 8,347 2,710 SH   SOLE   2,710 0 0
POSEIDA THERAPEUTICS INC COM 73730P108 BBG00BNTZ9J8 37,977 12,330 SH   SOLE 1 12,330 0 0
PROSHARES TR PSHS ULTRUSS2000 74347R842 BBG001S5RN32 480,231 15,092 SH   SOLE   15,092 0 0
REGENERON PHARMACEUTICALS COM 75886F107 BBG001S6PX49 241,570 294 SH   SOLE 1 294 0 0
REGENERON PHARMACEUTICALS COM 75886F107 BBG001S6PX49 51,765 63 SH   SOLE   63 0 0
SCHWAB STRATEGIC TR US SML CAP ETF 808524607 BBG001T5XQW5 430,683 10,271 SH   SOLE 1 10,271 0 0
SELECT SECTOR SPDR TR ENERGY 81369Y506 BBG001S7T1S7 506,897 6,120 SH   SOLE 1 6,120 0 0
SELECT SECTOR SPDR TR RL EST SEL SEC 81369Y860 BBG00B597137 1,019,175 27,265 SH   SOLE 1 27,265 0 0
SPDR S&P 500 ETF TR TR UNIT 78462F103 BBG001S72SM3 978 2 SH   SOLE 1 2 0 0
SPDR S&P 500 ETF TR TR UNIT 78462F103 BBG001S72SM3 8,059,335 19,686 SH   SOLE   19,686 0 0
SPDR SER TR BLOOMBERG HIGH Y 78468R622 BBG001SQS7X7 107,604 1,159 SH   SOLE 1 1,159 0 0
SPDR SER TR BLOOMBERG HIGH Y 78468R622 BBG001SQS7X7 292,896 3,156 SH   SOLE   3,156 0 0
SPDR SER TR BLOOMBERG INVT 78468R200 BBG0029J2J00 650,358 21,372 SH   SOLE 1 21,372 0 0
SPDR SER TR BLOOMBERG INVT 78468R200 BBG0029J2J00 1,182,490 38,859 SH   SOLE   38,859 0 0
SPDR SER TR FTSE INT GVT ETF 78464A490 BBG001STK554 1,569,954 36,326 SH   SOLE 1 36,326 0 0
SPDR SER TR FTSE INT GVT ETF 78464A490 BBG001STK554 4,338,047 100,372 SH   SOLE   100,372 0 0
SURFACE ONCOLOGY INC COM 86877M209 BBG00KFWYX53 7,645 10,938 SH   SOLE   10,938 0 0
SURFACE ONCOLOGY INC COM 86877M209 BBG00KFWYX53 35,092 50,218 SH   SOLE 1 50,218 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102 BBG001S5WS08 228,896 397 SH   SOLE 1 397 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102 BBG001S5WS08 45,099 78 SH   SOLE   78 0 0
TIDAL ETF TR RPAR RISK PARI 886364603 BBG00R24NZQ8 172,195 8,805 SH   SOLE 1 8,805 0 0
TIDAL ETF TR RPAR RISK PARI 886364603 BBG00R24NZQ8 399,677 20,434 SH   SOLE   20,434 0 0
UNITEDHEALTH GROUP INC COM 91324P102 BBG001S6WCJ1 46,535 97 SH   SOLE   97 0 0
UNITEDHEALTH GROUP INC COM 91324P102 BBG001S6WCJ1 207,528 439 SH   SOLE 1 439 0 0
VANGUARD CHARLOTTE FDS TOTAL INT BD ETF 92203J407 BBG004N1LGK2 1,210,486 24,744 SH   SOLE   24,744 0 0
VANGUARD CHARLOTTE FDS TOTAL INT BD ETF 92203J407 BBG004N1LGK2 493,592 10,090 SH   SOLE 1 10,090 0 0
VANGUARD INDEX FDS REAL ESTATE ETF 922908553 BBG001SMD2X3 4,421,684 53,250 SH   SOLE   53,250 0 0
VANGUARD INDEX FDS REAL ESTATE ETF 922908553 BBG001SMD2X3 330,607 3,981 SH   SOLE 1 3,981 0 0
VANGUARD INDEX FDS SMALL CP ETF 922908751 BBG001SHTTV0 2,145,207 11,316 SH   SOLE   11,316 0 0
VANGUARD INDEX FDS VALUE ETF 922908744 BBG001SHVR78 1,564,799 11,328 SH   SOLE   11,328 0 0
VANGUARD INDEX FDS VALUE ETF 922908744 BBG001SHVR78 273,380 1,980 SH   SOLE 1 1,980 0 0
VANGUARD INTL EQUITY INDEX F FTSE EMR MKT ETF 922042858 BBG001SHTTZ6 10,992,176 272,084 SH   SOLE   272,084 0 0
VANGUARD INTL EQUITY INDEX F FTSE EMR MKT ETF 922042858 BBG001SHTTZ6 4,879,129 120,770 SH   SOLE 1 120,770 0 0
VANGUARD INTL EQUITY INDEX F GLB EX US ETF 922042676 BBG001TCVT65 2,823,340 69,590 SH   SOLE   69,590 0 0
VANGUARD INTL EQUITY INDEX F GLB EX US ETF 922042676 BBG001TCVT65 892,155 21,990 SH   SOLE 1 21,990 0 0
VANGUARD TAX-MANAGED FDS VAN FTSE DEV MKT 921943858 BBG001SSPWL4 12,062,710 267,051 SH   SOLE   267,051 0 0
VANGUARD WHITEHALL FDS EM MK GOV BD ETF 921946885 BBG004N1LYJ5 374,552 6,011 SH   SOLE 1 6,011 0 0
VANGUARD WORLD FD EXTENDED DUR 921910709 BBG001SV5CV2 853,042 9,423 SH   SOLE 1 9,423 0 0
VANGUARD WORLD FD EXTENDED DUR 921910709 BBG001SV5CV2 4,542,637 50,173 SH   SOLE   50,173 0 0
WISDOMTREE TR US SMALLCAP FUND 97717W562 BBG001SSZBC9 1,524,477 35,274 SH   SOLE 1 35,274 0 0
WISDOMTREE TR US SMALLCAP FUND 97717W562 BBG001SSZBC9 316,939 7,335 SH   SOLE   7,335 0 0