The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABBOTT LABS COM 002824100   435,327 3,955 SH   SOLE   3,955 0 0
ABBVIE INC COM 00287Y109   1,378,148 8,893 SH   SOLE   8,893 0 0
ADVANCED MICRO DEVICES INC COM 007903107   646,098 4,383 SH   SOLE   4,383 0 0
AGNC INVT CORP COM 00123Q104   1,765,800 180,000 SH   SOLE   180,000 0 0
AKERO THERAPEUTICS INC COM 00973Y108   1,395,793 59,777 SH   SOLE   59,777 0 0
ALIGN TECHNOLOGY INC COM 016255101   1,100,932 4,018 SH   SOLE   4,018 0 0
AMERICAN AIRLS GROUP INC COM 02376R102   1,612,800 120,000 SH Put SOLE   120,000 0 0
AMGEN INC COM 031162100   434,910 1,510 SH   SOLE   1,510 0 0
ANNALY CAPITAL MANAGEMENT IN COM NEW 035710839   1,805,284 93,200 SH   SOLE   93,200 0 0
APPLIED THERAPEUTICS INC COM 03828A101   8,098,642 2,417,505 SH   SOLE   2,417,505 0 0
ARDELYX INC COM 039697107   2,170,000 350,000 SH   SOLE   350,000 0 0
ARGENX SE SPONSORED ADR 04016X101   676,405 1,778 SH   SOLE   1,778 0 0
ARMOUR RESIDENTIAL REIT INC COM SHS 042315705   289,800 15,000 SH   SOLE   15,000 0 0
ASML HOLDING N V N Y REGISTRY SHS N07059210   238,430 315 SH   SOLE   315 0 0
ATHIRA PHARMA INC COM 04746L104   3,627,485 1,492,792 SH   SOLE   1,492,792 0 0
AVIDITY BIOSCIENCES INC COM 05370A108   1,131,250 125,000 SH   SOLE   125,000 0 0
BANK OZK LITTLE ROCK ARK COM 06417N103   597,000 12,000 SH Put SOLE   12,000 0 0
BECTON DICKINSON & CO COM 075887109   1,293,518 5,305 SH   SOLE   5,305 0 0
BIO-TECHNE CORP COM 09073M104   329,010 4,264 SH   SOLE   4,264 0 0
BLOCK INC CL A 852234103   227,950 2,947 SH   SOLE   2,947 0 0
BOSTON SCIENTIFIC CORP COM 101137107   1,681,577 29,088 SH   SOLE   29,088 0 0
BRISTOL-MYERS SQUIBB CO COM 110122108   1,054,267 20,547 SH   SOLE   20,547 0 0
CAESARS ENTERTAINMENT INC NE COM 12769G100   1,194,500 25,000 SH Put SOLE   25,000 0 0
CARNIVAL CORP UNIT 99/99/9999 143658300   605,150 35,000 SH Put SOLE   35,000 0 0
CENTRAL & EASTERN EUROPE FD COM 153436100   379,831 38,957 SH   SOLE   38,957 0 0
COOPER COS INC COM NEW 216648402   263,394 696 SH   SOLE   696 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107   4,091,700 115,000 SH   SOLE   115,000 0 0
CYBIN INC COM 23256X100   205,000 500,000 SH   SOLE   500,000 0 0
CYTOKINETICS INC COM NEW 23282W605   1,819,832 21,797 SH   SOLE   21,797 0 0
DAY ONE BIOPHARMACEUTICALS I COM 23954D109   2,555,263 175,018 SH   SOLE   175,018 0 0
DELTA AIR LINES INC DEL COM NEW 247361702   1,820,250 45,000 SH Put SOLE   45,000 0 0
DEXCOM INC COM 252131107   930,427 7,498 SH   SOLE   7,498 0 0
ELI LILLY & CO COM 532457108   2,418,535 4,149 SH   SOLE   4,149 0 0
ESTABLISHMENT LABS HLDGS INC COM G31249108   307,133 11,863 SH   SOLE   11,863 0 0
EXACT SCIENCES CORP COM 30063P105   664,414 8,981 SH   SOLE   8,981 0 0
FULCRUM THERAPEUTICS INC COM 359616109   3,802,444 563,325 SH   SOLE   563,325 0 0
GENERAC HLDGS INC COM 368736104   1,082,645 8,500 SH Call SOLE   8,500 0 0
GILEAD SCIENCES INC COM 375558103   1,356,918 16,750 SH   SOLE   16,750 0 0
HUMANA INC COM 444859102   2,452,488 5,357 SH   SOLE   5,357 0 0
IDEXX LABS INC COM 45168D104   729,891 1,315 SH   SOLE   1,315 0 0
INSULET CORP COM 45784P101   903,288 4,163 SH   SOLE   4,163 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602   1,844,347 5,467 SH   SOLE   5,467 0 0
ISHARES GOLD TR ISHARES NEW 464285204   1,901,307 48,714 SH   SOLE   48,714 0 0
ISHARES TR IBOXX INV CP ETF 464287242   5,495,500 50,000 SH Call SOLE   50,000 0 0
ISHARES TR 20 YR TR BD ETF 464287432   204,779,730 2,083,000 SH Put SOLE   2,083,000 0 0
ISHARES TR IBOXX INV CP ETF 464287242   54,955,000 500,000 SH Put SOLE   500,000 0 0
ISHARES TR BLACKROCK ULTRA 46434V878   752,832 14,949 SH   SOLE   14,949 0 0
ISHARES TR IBONDS DEC24 ETF 46434VBG4   2,128,360 85,442 SH   SOLE   85,442 0 0
ISHARES TR RUSSELL 2000 ETF 464287655   37,908,800 190,000 SH Put SOLE   190,000 0 0
ISHARES TR 20 YR TR BD ETF 464287432   145,774,068 1,482,800 SH Call SOLE   1,482,800 0 0
ISHARES TR CORE US AGGBD ET 464287226   7,979,700 80,400 SH   SOLE   80,400 0 0
ISHARES TR MBS ETF 464288588   7,582,848 80,600 SH   SOLE   80,600 0 0
ISHARES TR 0-5YR INVT GR CP 46434V100   597,682 12,148 SH   SOLE   12,148 0 0
ISHARES TR CORE S&P500 ETF 464287200   288,883,520 604,827 SH   SOLE   604,827 0 0
ISHARES TR IBOXX INV CP ETF 464287242   10,452,501 94,456 SH   SOLE   94,456 0 0
JOHNSON & JOHNSON COM 478160104   2,352,354 15,008 SH   SOLE   15,008 0 0
KAYNE ANDERSON ENERGY INFRST COM 486606106   1,258,602 147,033 SH   SOLE   147,033 0 0
KURA ONCOLOGY INC COM 50127T109   1,150,400 80,000 SH   SOLE   80,000 0 0
KYMERA THERAPEUTICS INC COM 501575104   776,912 30,515 SH   SOLE   30,515 0 0
LANTHEUS HLDGS INC COM 516544103   237,956 3,838 SH   SOLE   3,838 0 0
LEMONADE INC COM 52567D107   218,239 13,530 SH   SOLE   13,530 0 0
LIVANOVA PLC SHS G5509L101   207,322 4,007 SH   SOLE   4,007 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105   3,307,346 14,294 SH   SOLE   14,294 0 0
MARINUS PHARMACEUTICALS INC COM NEW 56854Q200   1,630,500 150,000 SH   SOLE   150,000 0 0
MASIMO CORP COM 574795100   4,326,924 36,916 SH   SOLE   36,916 0 0
MEDTRONIC PLC SHS G5960L103   2,261,825 27,456 SH   SOLE   27,456 0 0
MERCK & CO INC COM 58933Y105   2,419,045 22,189 SH   SOLE   22,189 0 0
MICROSOFT CORP COM 594918104   395,970 1,053 SH   SOLE   1,053 0 0
MIRUM PHARMACEUTICALS INC COM 604749101   2,066,400 70,000 SH   SOLE   70,000 0 0
NVIDIA CORPORATION COM 67066G104   511,067 1,032 SH   SOLE   1,032 0 0
OAKTREE SPECIALTY LENDING CO COM 67401P405   3,298,034 161,510 SH   SOLE   161,510 0 0
PHATHOM PHARMACEUTICALS INC COM 71722W107   2,172,347 237,935 SH   SOLE   237,935 0 0
PIMCO ETF TR 15+ YR US TIPS 72201R304   15,546,360 274,283 SH   SOLE   274,283 0 0
PLAINS GP HLDGS L P LTD PARTNR INT A 72651A207   21,889,142 1,372,360 SH   SOLE   1,372,360 0 0
PURECYCLE TECHNOLOGIES INC COM 74623V103   1,341,194 331,159 SH   SOLE   331,159 0 0
QUANTERIX CORP COM 74766Q101   604,241 22,101 SH   SOLE   22,101 0 0
QUIDELORTHO CORP COM 219798105   266,057 3,610 SH   SOLE   3,610 0 0
REGENERON PHARMACEUTICALS COM 75886F107   3,520,186 4,008 SH   SOLE   4,008 0 0
RESMED INC COM 761152107   311,700 1,812 SH   SOLE   1,812 0 0
RIVIAN AUTOMOTIVE INC COM CL A 76954A103   738,500 35,000 SH Put SOLE   35,000 0 0
RIVIAN AUTOMOTIVE INC COM CL A 76954A103   16,422 700 SH   SOLE   700 0 0
SARATOGA INVT CORP COM NEW 80349A208   1,336,962 51,700 SH   SOLE   51,700 0 0
SAREPTA THERAPEUTICS INC COM 803607100   2,286,837 23,715 SH   SOLE   23,715 0 0
SHOCKWAVE MED INC COM 82489T104   809,118 4,246 SH   SOLE   4,246 0 0
SIMPLIFY EXCHANGE TRADED FUN TAIL RISK STRAT 82889N780   710,850 3,500,000 SH   SOLE   3,500,000 0 0
SIMPLIFY EXCHANGE TRADED FUN STABLE INCM ETF 82889N640   26,707,516 1,069,370 SH   SOLE   1,069,370 0 0
SIMPLIFY EXCHANGE TRADED FUN HIGH YIELD PLUS 82889N830   5,707,264 250,154 SH   SOLE   250,154 0 0
SIMPLIFY EXCHANGE TRADED FUN SHORT TERM TREA 82889N657   7,971,101 344,324 SH   SOLE   344,324 0 0
SIMPLIFY EXCHANGE TRADED FUN ENHANCED INM ETF 82889N632   2,956,140 120,364 SH   SOLE   120,364 0 0
SIMPLIFY EXCHANGE TRADED FUN COMMODITIES STRA 82889N566   1,427,598 61,244 SH   SOLE   61,244 0 0
SIMPLIFY EXCHANGE TRADED FUN SIMPLIFY INTERST 82889N855   1,173,800 29,345 SH   SOLE   29,345 0 0
SIMPLIFY EXCHANGE TRADED FUN INTMD TERM TRSRY 82889N798   627,641 44,169 SH   SOLE   44,169 0 0
SIMPLIFY EXCHANGE TRADED FUN MANAGED FUTURES 82889N699   3,611,555 153,032 SH   SOLE   153,032 0 0
SIMPLIFY EXCHANGE TRADED FUN AGGREGATE BOND E 82889N723   109,518,235 4,960,065 SH   SOLE   4,960,065 0 0
SIMPLIFY EXCHANGE TRADED FUN MULTI QIS ALTERN 82889N533   1,532,020 62,000 SH   SOLE   62,000 0 0
SIMPLIFY EXCHANGE TRADED FUN US EQUITY PLUS 82889N517   2,539,099 96,002 SH   SOLE   96,002 0 0
SIMPLIFY EXCHANGE TRADED FUN MBS ETF 82889N525   3,221,941 62,332 SH   SOLE   62,332 0 0
SPDR SER TR PORTFOLIO SHORT 78464A474   1,360,797 45,695 SH   SOLE   45,695 0 0
SPDR SER TR BLOOMBERG 1-3 MO 78468R663   1,721,331 18,835 SH   SOLE   18,835 0 0
SPDR SER TR BLOOMBERG INVT 78468R200   283,478 9,267 SH   SOLE   9,267 0 0
STRYKER CORPORATION COM 863667101   707,624 2,363 SH   SOLE   2,363 0 0
SUTRO BIOPHARMA INC COM 869367102   514,800 120,000 SH   SOLE   120,000 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105   255,020 11,801 SH   SOLE   11,801 0 0
TELESAT CORP CL A & CL B SHS 879512309   3,032,846 290,781 SH   SOLE   290,781 0 0
TESLA INC COM 88160R101   13,265,628 53,400 SH Call SOLE   53,400 0 0
TESLA INC COM 88160R101   427,386 1,720 SH   SOLE   1,720 0 0
THE CIGNA GROUP COM 125523100   3,498,774 11,684 SH   SOLE   11,684 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102   2,599,279 4,897 SH   SOLE   4,897 0 0
TRINITY CAP INC COM 896442308   494,020 34,000 SH Put SOLE   34,000 0 0
TSCAN THERAPEUTICS INC COM 89854M101   6,103,520 1,046,916 SH   SOLE   1,046,916 0 0
UNITEDHEALTH GROUP INC COM 91324P102   1,848,436 3,511 SH   SOLE   3,511 0 0
VANGUARD BD INDEX FDS SHORT TRM BOND 921937827   2,134,378 27,712 SH   SOLE   27,712 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100   940,323 2,311 SH   SOLE   2,311 0 0
X4 PHARMACEUTICALS INC COM 98420X103   335,400 400,000 SH   SOLE   400,000 0 0
ZOETIS INC CL A 98978V103   262,699 1,331 SH   SOLE   1,331 0 0