The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ARCA BIOPHARMA INC COM 00211Y506   1,201,781 706,930 SH   SOLE   0 0 706,930
ABERCROMBIE & FITCH CO CL A 002896207   3,033,000 900 SH Put SOLE   0 0 900
ACLARIS THERAPEUTICS INC COM 00461U105   685,762 653,107 SH   SOLE   0 0 653,107
ADVERUM BIOTECHNOLOGIES INC COM 00773U108   3,428,441 4,554,252 SH   SOLE   0 0 4,554,252
ASTROTECH CORP COM 046484309   1,871,281 220,410 SH   SOLE   0 0 220,410
ATEA PHARMACEUTICALS INC COM 04683R106   16,659,341 5,462,079 SH   SOLE   0 0 5,462,079
ATHIRA PHARMA INC COM 04746L104   3,534,100 1,454,362 SH   SOLE   0 0 1,454,362
AVROBIO INC COM 05455M100   5,442,213 4,001,627 SH   SOLE   0 0 4,001,627
BUILD-A-BEAR WORKSHOP INC COM 120076104   465,000 1,500 SH Put SOLE   0 0 1,500
LISATA THERAPEUTICS INC COM 128058302   736,660 269,839 SH   SOLE   0 0 269,839
CONNECT BIOPHARMA HLDGS LTD ADS 207523101   2,432,497 2,061,438 SH   SOLE   0 0 2,061,438
CYTEIR THERAPEUTICS INC COM 23284P103   9,880,024 3,250,008 SH   SOLE   0 0 3,250,008
DESIGN THERAPEUTICS INC COM 25056L103   2,728,117 1,029,478 SH   SOLE   0 0 1,029,478
ELIEM THERAPEUTICS INC COM 28658R106   5,886,000 2,180,000 SH   SOLE   0 0 2,180,000
ENLIVEN THERAPEUTICS INC COM 29337E102   692,000 50,000 SH   SOLE   0 0 50,000
FORTE BIOSCIENCES INC COM 34962G109   1,447,591 1,761,702 SH   SOLE   0 0 1,761,702
GRAPHITE BIO INC COM 38870X104   1,172,230 447,416 SH   SOLE   0 0 447,416
CALCIMEDICA INC COM NEW 38942Q202   415,913 145,424 SH   SOLE   0 0 145,424
HOMOLOGY MEDICINES INC COM 438083107   454,850 748,108 SH   SOLE   0 0 748,108
INVESCO QQQ TR UNIT SER 1 46090E103   661,200 300 SH Put SOLE   0 0 300
ISHARES TR 0-3 MNTH TREASRY 46436E718   27,072,900 270,000 SH   SOLE   0 0 270,000
KINNATE BIOPHARMA INC COM 49705R105   1,109,658 468,210 SH   SOLE   0 0 468,210
MILESTONE PHARMACEUTICALS IN COM 59935V107   738,728 442,352 SH   SOLE   0 0 442,352
NEUROGENE INC COM 64135M105   478,027 24,666 SH   SOLE   0 0 24,666
NEXTCURE INC COM 65343E108   349,370 306,465 SH   SOLE   0 0 306,465
ORAMED PHARMACEUTICALS INC COM NEW 68403P203   2,914,201 1,261,559 SH   SOLE   0 0 1,261,559
RAIN ONCOLOGY INC COM 75082Q105   1,618,808 1,349,007 SH   SOLE   0 0 1,349,007
RENEO PHARMACEUTICALS INC COM 75974E103   2,102,766 1,314,229 SH   SOLE   0 0 1,314,229
SPDR SER TR BLOOMBERG 1-3 MO 78468R663   18,278,000 200,000 SH   SOLE   0 0 200,000
TALIS BIOMEDICAL CORP COM NEW 87424L207   318,435 42,743 SH   SOLE   0 0 42,743
THESEUS PHARMACEUTICALS INC COM 88369M101   4,488,696 1,108,320 SH   SOLE   0 0 1,108,320
TOURMALINE BIO INC COM 89157D105   6,427,190 245,500 SH   SOLE   0 0 245,500
VERRICA PHARMACEUTICALS INC COM 92511W108   1,317,600 180,000 SH   SOLE   0 0 180,000
VISTAGEN THERAPEUTICS INC COM 92840H400   771,000 150,000 SH   SOLE   0 0 150,000
WINGSTOP INC COM 974155103   1,210,500 900 SH Put SOLE   0 0 900