The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
3M CO COM 88579Y101   5,390,628 39,434 SH   SOLE   39,434 0 0
ABBOTT LABS COM 002824100   1,605,603 14,083 SH   SOLE   14,083 0 0
ABBVIE INC COM 00287Y109   9,331,325 47,252 SH   SOLE   47,252 0 0
ABEONA THERAPEUTICS INC COM NEW 00289Y206   2,582,251 408,584 SH   SOLE   408,584 0 0
ACHIEVE LIFE SCIENCES INC COM 004468500   1,032,585 217,845 SH   SOLE   217,845 0 0
ADVANCED MICRO DEVICES INC COM 007903107   588,391 3,586 SH   SOLE   3,586 0 0
AGILON HEALTH INC COM 00857U107   662,975 168,696 SH   SOLE   168,696 0 0
AGNC INVT CORP COM 00123Q104   1,380,720 132,000 SH   SOLE   132,000 0 0
AKERO THERAPEUTICS INC COM 00973Y108   8,141,247 283,766 SH   SOLE   283,766 0 0
ALPHABET INC CAP STK CL C 02079K107   211,997 1,268 SH   SOLE   1,268 0 0
AMAZON COM INC COM 023135106   220,801 1,185 SH   SOLE   1,185 0 0
ANNALY CAPITAL MANAGEMENT IN COM NEW 035710839   2,474,671 123,302 SH   SOLE   123,302 0 0
APPLE INC COM 037833100   232,301 997 SH   SOLE   997 0 0
APPLIED THERAPEUTICS INC COM 03828A101   23,948,792 2,817,505 SH   SOLE   2,817,505 0 0
ARDELYX INC COM 039697107   4,749,718 689,364 SH   SOLE   689,364 0 0
ARGENX SE SPONSORED ADR 04016X101   1,311,292 2,419 SH   SOLE   2,419 0 0
ARMOUR RESIDENTIAL REIT INC COM SHS 042315705   510,000 25,000 SH   SOLE   25,000 0 0
ASML HOLDING N V N Y REGISTRY SHS N07059210   208,312 250 SH   SOLE   250 0 0
ATHIRA PHARMA INC COM 04746L104   665,785 1,492,792 SH   SOLE   1,492,792 0 0
AVANTOR INC COM 05352A100   2,190,620 84,678 SH   SOLE   84,678 0 0
AVIDITY BIOSCIENCES INC COM 05370A108   5,741,250 125,000 SH   SOLE   125,000 0 0
BENITEC BIOPHARMA INC COM NEW 08205P209   1,070,957 116,535 SH   SOLE   116,535 0 0
BIOGEN INC COM 09062X103   478,785 2,470 SH   SOLE   2,470 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101   596,692 8,489 SH   SOLE   8,489 0 0
BIO-TECHNE CORP COM 09073M104   608,907 7,618 SH   SOLE   7,618 0 0
CAVA GROUP INC COM 148929102   619,250 5,000 SH Put SOLE   5,000 0 0
CENTRAL & EASTERN EUROPE FD COM 153436100   259,799 24,235 SH   SOLE   24,235 0 0
CHEWY INC CL A 16679L109   5,379,460 183,662 SH   SOLE   183,662 0 0
CHIMERA INVT CORP COM SHS 16934Q802   158,300 10,000 SH   SOLE   10,000 0 0
COOPER COS INC COM 216648501   978,495 8,868 SH   SOLE   8,868 0 0
DANAHER CORPORATION COM 235851102   576,057 2,072 SH   SOLE   2,072 0 0
ELEVANCE HEALTH INC COM 036752103   4,556,240 8,762 SH   SOLE   8,762 0 0
ELI LILLY & CO COM 532457108   16,905,507 19,082 SH   SOLE   19,082 0 0
ESTABLISHMENT LABS HLDGS INC COM G31249108   936,320 21,639 SH   SOLE   21,639 0 0
EXACT SCIENCES CORP COM 30063P105   1,994,349 29,277 SH   SOLE   29,277 0 0
FULCRUM THERAPEUTICS INC COM 359616109   1,254,191 351,314 SH   SOLE   351,314 0 0
GILEAD SCIENCES INC COM 375558103   8,065,576 96,202 SH   SOLE   96,202 0 0
GRAYSCALE BITCOIN MINI TR BT SHS 389930108   1,611,464 286,228 SH   SOLE   286,228 0 0
GRAYSCALE BITCOIN TR BTC SHS REP COM UT 389637109   1,724,676 34,152 SH   SOLE   34,152 0 0
HCA HEALTHCARE INC COM 40412C101   955,517 2,351 SH   SOLE   2,351 0 0
HENRY SCHEIN INC COM 806407102   435,359 5,972 SH   SOLE   5,972 0 0
INTRA-CELLULAR THERAPIES INC COM 46116X101   2,259,709 30,883 SH   SOLE   30,883 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602   11,412,202 23,230 SH   SOLE   23,230 0 0
IQVIA HLDGS INC COM 46266C105   2,283,680 9,637 SH   SOLE   9,637 0 0
ISHARES GOLD TR ISHARES NEW 464285204   1,097,624 22,085 SH   SOLE   22,085 0 0
ISHARES TR IBOXX HI YD ETF 464288513   125,557,080 1,563,600 SH Put SOLE   1,563,600 0 0
ISHARES TR CORE US AGGBD ET 464287226   142,763,458 1,409,731 SH   SOLE   1,409,731 0 0
ISHARES TR CORE S&P500 ETF 464287200   429,366,350 744,368 SH   SOLE   744,368 0 0
J P MORGAN EXCHANGE TRADED F ULTRA SHRT ETF 46641Q837   25,044,249 493,580 SH   SOLE   493,580 0 0
JOHNSON & JOHNSON COM 478160104   10,955,418 67,601 SH   SOLE   67,601 0 0
KIMBERLY-CLARK CORP COM 494368103   2,696,490 18,952 SH   SOLE   18,952 0 0
KURA ONCOLOGY INC COM 50127T109   1,563,200 80,000 SH   SOLE   80,000 0 0
KYMERA THERAPEUTICS INC COM 501575104   1,444,275 30,515 SH   SOLE   30,515 0 0
LEAP THERAPEUTICS INC COM NEW 52187K200   2,716,220 1,056,895 SH   SOLE   1,056,895 0 0
LEMONADE INC COM 52567D107   223,110 13,530 SH   SOLE   13,530 0 0
LIVANOVA PLC SHS G5509L101   753,739 14,346 SH   SOLE   14,346 0 0
MACERICH CO COM 554382101   1,003,200 55,000 SH Put SOLE   55,000 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105   4,945,787 23,305 SH   SOLE   23,305 0 0
META PLATFORMS INC CL A 30303M102   230,121 402 SH   SOLE   402 0 0
MICROSOFT CORP COM 594918104   266,356 619 SH   SOLE   619 0 0
MYRIAD GENETICS INC COM 62855J104   4,755,616 173,626 SH   SOLE   173,626 0 0
NVIDIA CORPORATION COM 67066G104   1,182,097 9,734 SH   SOLE   9,734 0 0
PENNYMAC MTG INVT TR COM 70931T103   142,600 10,000 SH   SOLE   10,000 0 0
PHATHOM PHARMACEUTICALS INC COM 71722W107   9,436,585 521,935 SH   SOLE   521,935 0 0
PIMCO ETF TR ENHAN SHRT MA AC 72201R833   25,353,742 251,800 SH   SOLE   251,800 0 0
PLAINS GP HLDGS L P LTD PARTNR INT A 72651A207   23,538,660 1,272,360 SH   SOLE   1,272,360 0 0
PURECYCLE TECHNOLOGIES INC COM 74623V103   16,834,532 1,772,056 SH   SOLE   1,772,056 0 0
QURATE RETAIL INC COM SER A 74915M100   213,535 350,000 SH   SOLE   350,000 0 0
REGENERON PHARMACEUTICALS COM 75886F107   10,082,443 9,591 SH   SOLE   9,591 0 0
REVVITY INC COM 714046109   3,104,708 24,303 SH   SOLE   24,303 0 0
RITHM CAPITAL CORP COM NEW 64828T201   1,496,280 134,800 SH   SOLE   134,800 0 0
ROYALTY PHARMA PLC SHS CLASS A G7709Q104   2,661,127 94,066 SH   SOLE   94,066 0 0
SANOFI SPONSORED ADR 80105N105   11,764,761 204,143 SH   SOLE   204,143 0 0
SAREPTA THERAPEUTICS INC COM 803607100   24,105,019 193,010 SH   SOLE   193,010 0 0
SCHWAB STRATEGIC TR US TIPS ETF 808524870   38,101,487 710,451 SH   SOLE   710,451 0 0
SIMPLIFY EXCHANGE TRADED FUN NATL MUNI BD ETF 82889N442   78,839,680 3,126,710 SH   SOLE   3,126,710 0 0
SIMPLIFY EXCHANGE TRADED FUN AGGREGATE BOND E 82889N723   112,745,544 5,193,254 SH   SOLE   5,193,254 0 0
SIMPLIFY EXCHANGE TRADED FUN MARKET NEUTRAL 82889N541   2,048,659 94,670 SH   SOLE   94,670 0 0
SIMPLIFY EXCHANGE TRADED FUN NEXT INTANGIBLE 82889N475   898,030 31,521 SH   SOLE   31,521 0 0
SIMPLIFY EXCHANGE TRADED FUN MBS ETF 82889N525   55,348,053 1,075,137 SH   SOLE   1,075,137 0 0
SIMPLIFY EXCHANGE TRADED FUN SHORT TERM TREA 82889N657   3,805,443 165,526 SH   SOLE   165,526 0 0
SIMPLIFY EXCHANGE TRADED FUN MULTI QIS ALTERN 82889N533   1,525,844 62,035 SH   SOLE   62,035 0 0
SIMPLIFY EXCHANGE TRADED FUN INTMD TERM TRSRY 82889N798   55,556,777 3,866,164 SH   SOLE   3,866,164 0 0
SIMPLIFY EXCHANGE TRADED FUN NEXT INTANGIBLE 82889N467   872,318 31,521 SH   SOLE   31,521 0 0
SIMPLIFY EXCHANGE TRADED FUN US EQUITY PLUS 82889N517   1,219,876 39,218 SH   SOLE   39,218 0 0
SIMPLIFY EXCHANGE TRADED FUN STABLE INCM ETF 82889N640   109,346,072 4,448,579 SH   SOLE   4,448,579 0 0
SIMPLIFY EXCHANGE TRADED FUN MANAGED FUTURES 82889N699   1,407,068 54,118 SH   SOLE   54,118 0 0
SIMPLIFY EXCHANGE TRADED FUN HIGH YIELD PLUS 82889N830   32,635,892 1,374,907 SH   SOLE   1,374,907 0 0
SPDR GOLD TR GOLD SHS 78463V107   561,152,622 2,308,700 SH Put SOLE   2,308,700 0 0
STRYKER CORPORATION COM 863667101   654,603 1,812 SH   SOLE   1,812 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105   2,352,061 122,185 SH   SOLE   122,185 0 0
TANDEM DIABETES CARE INC COM NEW 875372203   4,860,356 114,604 SH   SOLE   114,604 0 0
TELEFLEX INCORPORATED COM 879369106   4,799,987 19,408 SH   SOLE   19,408 0 0
TELESAT CORP CL A & CL B SHS 879512309   4,817,336 365,781 SH   SOLE   365,781 0 0
TENET HEALTHCARE CORP COM NEW 88033G407   1,308,326 7,872 SH   SOLE   7,872 0 0
TESLA INC COM 88160R101   3,924,450 15,000 SH Call SOLE   15,000 0 0
TESLA INC COM 88160R101   450,004 1,720 SH   SOLE   1,720 0 0
THE CIGNA GROUP COM 125523100   7,252,029 20,933 SH   SOLE   20,933 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102   8,517,709 13,770 SH   SOLE   13,770 0 0
TSCAN THERAPEUTICS INC COM 89854M101   5,213,642 1,046,916 SH   SOLE   1,046,916 0 0
TWO HBRS INVT CORP COM 90187B804   134,300 10,000 SH   SOLE   10,000 0 0
UNITEDHEALTH GROUP INC COM 91324P102   11,911,101 20,372 SH   SOLE   20,372 0 0
VEEVA SYS INC CL A COM 922475108   676,411 3,223 SH   SOLE   3,223 0 0
VERRICA PHARMACEUTICALS INC COM 92511W108   290,000 200,000 SH   SOLE   200,000 0 0
ZEVRA THERAPEUTICS INC COM NEW 488445206   832,800 120,000 SH   SOLE   120,000 0 0
ZIMMER BIOMET HOLDINGS INC COM 98956P102   381,603 3,535 SH   SOLE   3,535 0 0
ZOETIS INC CL A 98978V103   11,683,919 59,801 SH   SOLE   59,801 0 0