The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
3M CO COM 88579Y101   3,561,424 34,851 SH   SOLE   34,851 0 0
ABBOTT LABS COM 002824100   874,818 8,419 SH   SOLE   8,419 0 0
ABEONA THERAPEUTICS INC COM NEW 00289Y206   1,732,396 408,584 SH   SOLE   408,584 0 0
ACHIEVE LIFE SCIENCES INC COM 004468500   1,023,872 217,845 SH   SOLE   217,845 0 0
ADVANCED MICRO DEVICES INC COM 007903107   636,025 3,921 SH   SOLE   3,921 0 0
AGILON HEALTH INC COM 00857U107   658,761 100,728 SH   SOLE   100,728 0 0
AGNC INVT CORP COM 00123Q104   1,717,200 180,000 SH   SOLE   180,000 0 0
AKERO THERAPEUTICS INC COM 00973Y108   5,759,125 245,487 SH   SOLE   245,487 0 0
ALPHABET INC CAP STK CL C 02079K107   232,577 1,268 SH   SOLE   1,268 0 0
AMAZON COM INC COM 023135106   229,001 1,185 SH   SOLE   1,185 0 0
ANNALY CAPITAL MANAGEMENT IN COM NEW 035710839   1,776,392 93,200 SH   SOLE   93,200 0 0
APPLE INC COM 037833100   209,988 997 SH   SOLE   997 0 0
APPLIED THERAPEUTICS INC COM 03828A101   13,157,748 2,817,505 SH   SOLE   2,817,505 0 0
ARDELYX INC COM 039697107   4,431,180 598,000 SH   SOLE   598,000 0 0
ARGENX SE SPONSORED ADR 04016X101   634,309 1,475 SH   SOLE   1,475 0 0
ARMOUR RESIDENTIAL REIT INC COM SHS 042315705   290,700 15,000 SH   SOLE   15,000 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101   1,210,645 8,877 SH   SOLE   8,877 0 0
ASML HOLDING N V N Y REGISTRY SHS N07059210   255,682 250 SH   SOLE   250 0 0
ATHIRA PHARMA INC COM 04746L104   3,955,899 1,492,792 SH   SOLE   1,492,792 0 0
AVANTOR INC COM 05352A100   1,072,211 50,576 SH   SOLE   50,576 0 0
AVIDITY BIOSCIENCES INC COM 05370A108   5,106,250 125,000 SH   SOLE   125,000 0 0
BENITEC BIOPHARMA INC COM NEW 08205P209   358,000 51,216 SH   SOLE   51,216 0 0
BIOGEN INC COM 09062X103   362,103 1,562 SH   SOLE   1,562 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101   417,166 5,067 SH   SOLE   5,067 0 0
BIO-TECHNE CORP COM 09073M104   326,008 4,550 SH   SOLE   4,550 0 0
BOSTON SCIENTIFIC CORP COM 101137107   6,132,999 79,639 SH   SOLE   79,639 0 0
CARVANA CO CL A 146869102   22,526,000 175,000 SH Put SOLE   175,000 0 0
CARVANA CO CL A 146869102   1,287,200 10,000 SH Call SOLE   10,000 0 0
CENTRAL & EASTERN EUROPE FD COM 153436100   430,909 40,423 SH   SOLE   40,423 0 0
COOPER COS INC COM 216648501   1,775,507 20,338 SH   SOLE   20,338 0 0
CYBIN INC COM 23256X100   135,500 500,000 SH   SOLE   500,000 0 0
DANAHER CORPORATION COM 235851102   311,313 1,246 SH   SOLE   1,246 0 0
ELEVANCE HEALTH INC COM 036752103   2,837,179 5,236 SH   SOLE   5,236 0 0
ELI LILLY & CO COM 532457108   10,332,197 11,412 SH   SOLE   11,412 0 0
ESTABLISHMENT LABS HLDGS INC COM G31249108   586,494 12,907 SH   SOLE   12,907 0 0
EXACT SCIENCES CORP COM 30063P105   738,403 17,477 SH   SOLE   17,477 0 0
FULCRUM THERAPEUTICS INC COM 359616109   4,183,958 674,832 SH   SOLE   674,832 0 0
GRAYSCALE BITCOIN TR BTC SHS REP COM UT 389637109   2,122,519 39,867 SH   SOLE   39,867 0 0
HCA HEALTHCARE INC COM 40412C101   452,041 1,407 SH   SOLE   1,407 0 0
HENRY SCHEIN INC COM 806407102   236,850 3,695 SH   SOLE   3,695 0 0
HUMANA INC COM 444859102   2,162,686 5,788 SH   SOLE   5,788 0 0
INSMED INC COM PAR $.01 457669307   1,392,796 20,788 SH   SOLE   20,788 0 0
INTRA-CELLULAR THERAPIES INC COM 46116X101   1,269,599 18,537 SH   SOLE   18,537 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602   6,823,109 15,338 SH   SOLE   15,338 0 0
IQVIA HLDGS INC COM 46266C105   1,214,300 5,743 SH   SOLE   5,743 0 0
ISHARES GOLD TR ISHARES NEW 464285204   1,137,436 25,892 SH   SOLE   25,892 0 0
ISHARES SILVER TR ISHARES 46428Q109   69,286,589 2,607,700 SH Put SOLE   2,607,700 0 0
ISHARES TR MSCI EAFE ETF 464287465   75,384,792 962,400 SH Call SOLE   962,400 0 0
ISHARES TR CORE S&P500 ETF 464287200   384,355,199 702,365 SH   SOLE   702,365 0 0
ISHARES TR US HOME CONS ETF 464288752   104,475,828 1,033,800 SH Call SOLE   1,033,800 0 0
ISHARES TR CORE US AGGBD ET 464287226   164,299,808 1,692,591 SH   SOLE   1,692,591 0 0
JOHNSON & JOHNSON COM 478160104   3,437,683 23,520 SH   SOLE   23,520 0 0
KAYNE ANDERSON ENERGY INFRST COM 486606106   1,518,851 147,033 SH   SOLE   147,033 0 0
KURA ONCOLOGY INC COM 50127T109   1,647,200 80,000 SH   SOLE   80,000 0 0
KYMERA THERAPEUTICS INC COM 501575104   910,873 30,515 SH   SOLE   30,515 0 0
LEAP THERAPEUTICS INC COM NEW 52187K200   1,237,287 631,269 SH   SOLE   631,269 0 0
LEMONADE INC COM 52567D107   223,245 13,530 SH   SOLE   13,530 0 0
LIVANOVA PLC SHS G5509L101   469,478 8,564 SH   SOLE   8,564 0 0
LUMEN TECHNOLOGIES INC COM 550241103   550,000 500,000 SH   SOLE   500,000 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105   6,531,370 23,313 SH   SOLE   23,313 0 0
MASIMO CORP COM 574795100   2,729,120 21,670 SH   SOLE   21,670 0 0
MERCK & CO INC COM 58933Y105   6,351,188 51,302 SH   SOLE   51,302 0 0
META PLATFORMS INC CL A 30303M102   266,228 528 SH   SOLE   528 0 0
MICROSOFT CORP COM 594918104   420,580 941 SH   SOLE   941 0 0
NATERA INC COM 632307104   1,375,824 12,705 SH   SOLE   12,705 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109   3,143,557 22,834 SH   SOLE   22,834 0 0
NOVO-NORDISK A S ADR 670100205   5,627,810 39,427 SH   SOLE   39,427 0 0
NVIDIA CORPORATION COM 67066G104   1,202,538 9,734 SH   SOLE   9,734 0 0
PHATHOM PHARMACEUTICALS INC COM 71722W107   5,375,930 521,935 SH   SOLE   521,935 0 0
PLAINS GP HLDGS L P LTD PARTNR INT A 72651A207   25,827,815 1,372,360 SH   SOLE   1,372,360 0 0
PURECYCLE TECHNOLOGIES INC COM 74623V103   6,265,681 1,058,392 SH   SOLE   1,058,392 0 0
QURATE RETAIL INC COM SER A 74915M100   220,500 350,000 SH   SOLE   350,000 0 0
REGENERON PHARMACEUTICALS COM 75886F107   6,684,551 6,360 SH   SOLE   6,360 0 0
REVVITY INC COM 714046109   2,702,452 25,772 SH   SOLE   25,772 0 0
RITHM CAPITAL CORP COM NEW 64828T201   381,628 35,800 SH   SOLE   35,800 0 0
ROYALTY PHARMA PLC SHS CLASS A G7709Q104   1,481,678 56,188 SH   SOLE   56,188 0 0
SAREPTA THERAPEUTICS INC COM 803607100   16,516,688 104,536 SH   SOLE   104,536 0 0
SCHWAB STRATEGIC TR US TIPS ETF 808524870   31,501,729 605,686 SH   SOLE   605,686 0 0
SELECT SECTOR SPDR TR ENERGY 81369Y506   26,278,545 288,300 SH Call SOLE   288,300 0 0
SIMPLIFY EXCHANGE TRADED FUN INTMD TERM TRSRY 82889N798   348,938 26,945 SH   SOLE   26,945 0 0
SIMPLIFY EXCHANGE TRADED FUN HIGH YIELD PLUS 82889N830   92,918,344 4,045,997 SH   SOLE   4,045,997 0 0
SIMPLIFY EXCHANGE TRADED FUN MBS ETF 82889N525   44,541,053 884,453 SH   SOLE   884,453 0 0
SIMPLIFY EXCHANGE TRADED FUN NEXT INTANGIBLE 82889N475   968,288 36,956 SH   SOLE   36,956 0 0
SIMPLIFY EXCHANGE TRADED FUN MANAGED FUTURES 82889N699   2,150,450 79,883 SH   SOLE   79,883 0 0
SIMPLIFY EXCHANGE TRADED FUN AGGREGATE BOND E 82889N723   101,656,343 4,896,741 SH   SOLE   4,896,741 0 0
SIMPLIFY EXCHANGE TRADED FUN MULTI QIS ALTERN 82889N533   1,501,176 59,335 SH   SOLE   59,335 0 0
SIMPLIFY EXCHANGE TRADED FUN MARKET NEUTRAL 82889N541   2,871,422 121,722 SH   SOLE   121,722 0 0
SIMPLIFY EXCHANGE TRADED FUN SHORT TERM TREA 82889N657   2,163,639 101,484 SH   SOLE   101,484 0 0
SIMPLIFY EXCHANGE TRADED FUN NEXT INTANGIBLE 82889N467   960,246 36,956 SH   SOLE   36,956 0 0
SIMPLIFY EXCHANGE TRADED FUN STABLE INCM ETF 82889N640   79,180,333 3,216,098 SH   SOLE   3,216,098 0 0
SIMPLIFY EXCHANGE TRADED FUN US EQUITY PLUS 82889N517   1,383,961 45,978 SH   SOLE   45,978 0 0
SPDR SER TR S&P REGL BKG 78464A698   24,265,220 494,200 SH Put SOLE   494,200 0 0
SPDR SER TR S&P OILGAS EXP 78468R556   25,602,720 176,000 SH Put SOLE   176,000 0 0
STRYKER CORPORATION COM 863667101   375,636 1,104 SH   SOLE   1,104 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105   1,543,712 75,193 SH   SOLE   75,193 0 0
TELESAT CORP CL A & CL B SHS 879512309   3,328,607 365,781 SH   SOLE   365,781 0 0
TENET HEALTHCARE CORP COM NEW 88033G407   623,379 4,686 SH   SOLE   4,686 0 0
TESLA INC COM 88160R101   340,354 1,720 SH   SOLE   1,720 0 0
TESLA INC COM 88160R101   2,968,200 15,000 SH Call SOLE   15,000 0 0
THE CIGNA GROUP COM 125523100   1,615,826 4,888 SH   SOLE   4,888 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102   4,547,872 8,224 SH   SOLE   8,224 0 0
TREVI THERAPEUTICS INC COM 89532M101   596,000 200,000 SH   SOLE   200,000 0 0
TSCAN THERAPEUTICS INC COM 89854M101   6,124,459 1,046,916 SH   SOLE   1,046,916 0 0
TWIST BIOSCIENCE CORP COM 90184D100   1,255,211 25,471 SH   SOLE   25,471 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108   1,259,756 30,651 SH   SOLE   30,651 0 0
UNITEDHEALTH GROUP INC COM 91324P102   6,925,936 13,600 SH   SOLE   13,600 0 0
VEEVA SYS INC CL A COM 922475108   352,294 1,925 SH   SOLE   1,925 0 0
VERRICA PHARMACEUTICALS INC COM 92511W108   2,041,200 280,000 SH   SOLE   280,000 0 0
ZIMMER BIOMET HOLDINGS INC COM 98956P102   221,184 2,038 SH   SOLE   2,038 0 0