The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
4D MOLECULAR THERAPEUTICS IN COM 35104E100   6,279,542 197,098 SH   SOLE   197,098 0 0
AMICUS THERAPEUTICS INC COM 03152W109   682,839 57,966 SH   SOLE   57,966 0 0
ANNEXON INC COM 03589W102   2,096,508 292,400 SH   SOLE   292,400 0 0
APOGEE THERAPEUTICS INC COM 03770N101   1,329,000 20,000 SH   SOLE   20,000 0 0
APPLIED THERAPEUTICS INC COM 03828A101   10,641,429 1,564,916 SH   SOLE   1,564,916 0 0
ARCELLX INC COMMON STOCK 03940C100   10,432,500 150,000 SH   SOLE   150,000 0 0
ARCUTIS BIOTHERAPEUTICS INC COM 03969K108   2,229,750 225,000 SH   SOLE   225,000 0 0
AVITA MEDICAL INC COM 05380C102   1,202,250 75,000 SH   SOLE   75,000 0 0
AXOGEN INC COM 05463X106   25,063,927 3,105,815 SH   SOLE   3,105,815 0 0
BAUSCH HEALTH COS INC COM 071734107   7,108,700 670,000 SH   SOLE   670,000 0 0
BEIGENE LTD SPONSORED ADR 07725L102   23,161,359 148,100 SH   SOLE   148,100 0 0
BICYCLE THERAPEUTICS PLC SPONSORED ADS 088786108   3,809,700 153,000 SH   SOLE   153,000 0 0
BIOATLA INC COM 09077B104   13,984,278 4,065,197 SH   SOLE   4,065,197 0 0
BIOGEN INC COM 09062X103   15,697,864 72,800 SH   SOLE   72,800 0 0
C4 THERAPEUTICS INC COM STK 12529R107   20,089,997 2,458,996 SH   SOLE   2,458,996 0 0
CALCIMEDICA INC COM NEW 38942Q202   3,261,041 783,904 SH   SOLE   783,904 0 0
CASTLE BIOSCIENCES INC COM 14843C105   16,068,873 725,457 SH   SOLE   725,457 0 0
CELCUITY INC COM 15102K100   37,396,901 1,731,338 SH   SOLE   1,731,338 0 0
CERVOMED INC COM 15713L109   2,950,106 126,614 SH   SOLE   126,614 0 0
CG ONCOLOGY INC COM 156944100   9,564,537 217,871 SH   SOLE   217,871 0 0
COMPASS PATHWAYS PLC SPONSORED ADS 20451W101   4,705,376 565,550 SH   SOLE   565,550 0 0
CVRX INC COM 126638105   883,185 48,500 SH   SOLE   48,500 0 0
DENALI THERAPEUTICS INC COM 24823R105   964,440 47,000 SH   SOLE   47,000 0 0
DIANTHUS THERAPEUTICS INC COM 252828108   3,000,000 100,000 SH   SOLE   100,000 0 0
EDAP TMS S A SPONSORED ADR 268311107   53,121,045 7,227,353 SH   SOLE   7,227,353 0 0
ENANTA PHARMACEUTICALS INC COM 29251M106   10,136,333 580,546 SH   SOLE   580,546 0 0
ENGENE HOLDINGS INC COM 29286M105   13,560,000 800,000 SH   SOLE   800,000 0 0
ESSA PHARMA INC COM NEW 29668H708   30,475,347 3,589,558 SH   SOLE   3,589,558 0 0
EVOLUS INC COM 30052C107   2,240,000 160,000 SH   SOLE   160,000 0 0
FATE THERAPEUTICS INC COM 31189P102   6,385,800 870,000 SH   SOLE   870,000 0 0
GENEDX HOLDINGS CORP COM CL A 81663L200   7,152,223 783,376 SH   SOLE   783,376 0 0
GSK PLC SPONSORED ADR 37733W204   13,684,833 319,217 SH   SOLE   319,217 0 0
HCA HEALTHCARE INC COM 40412C101   17,157,117 51,441 SH   SOLE   51,441 0 0
HUMANA INC COM 444859102   24,965,920 72,006 SH   SOLE   72,006 0 0
IDEAYA BIOSCIENCES INC COM 45166A102   23,410,638 533,515 SH   SOLE   533,515 0 0
IMMUNIC INC COM 4525EP101   9,626,769 7,293,007 SH   SOLE   7,293,007 0 0
IMMUNOVANT INC COM 45258J102   8,550,842 264,650 SH   SOLE   264,650 0 0
INARI MED INC COM 45332Y109   13,290,460 277,000 SH   SOLE   277,000 0 0
INHIBRX INC COM 45720L107   9,364,770 267,871 SH   SOLE   267,871 0 0
INSMED INC COM PAR $.01 457669307   6,782,500 250,000 SH   SOLE   250,000 0 0
INSPIREMD INC COM 45779A846   3,266,301 1,378,128 SH   SOLE   1,378,128 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100   51,944,100 3,505,000 SH   SOLE   3,505,000 0 0
IRADIMED CORP COM 46266A109   15,908,104 361,630 SH   SOLE   361,630 0 0
JANUX THERAPEUTICS INC COM 47103J105   5,941,170 157,800 SH   SOLE   157,800 0 0
JASPER THERAPEUTICS INC COM NEW 471871202   34,853,139 1,187,096 SH   SOLE   1,187,096 0 0
KALVISTA PHARMACEUTICALS INC COM 483497103   4,577,960 386,000 SH   SOLE   386,000 0 0
KEROS THERAPEUTICS INC COM 492327101   18,112,320 273,600 SH   SOLE   273,600 0 0
KRYSTAL BIOTECH INC COM 501147102   14,963,913 84,100 SH   SOLE   84,100 0 0
LIQUIDIA CORPORATION COM NEW 53635D202   147,500 10,000 SH   SOLE   10,000 0 0
MANNKIND CORP COM NEW 56400P706   7,060,173 1,558,537 SH   SOLE   1,558,537 0 0
MEREO BIOPHARMA GROUP PLC SPON ADS 589492107   8,635,945 2,616,953 SH   SOLE   2,616,953 0 0
MERUS N V COM N5749R100   8,806,832 195,577 SH   SOLE   195,577 0 0
MIND MEDICINE MINDMED INC COM NEW 60255C885   7,052,228 750,237 SH   SOLE   750,237 0 0
NATERA INC COM 632307104   7,957,020 87,000 SH   SOLE   87,000 0 0
NEUROPACE INC COM 641288105   32,117,818 2,433,168 SH   SOLE   2,433,168 0 0
NKARTA INC COM 65487U108   3,243,000 300,000 SH   SOLE   300,000 0 0
NOVOCURE LTD ORD SHS G6674U108   10,874,713 695,759 SH   SOLE   695,759 0 0
NURIX THERAPEUTICS INC COM 67080M103   16,390,500 1,115,000 SH   SOLE   1,115,000 0 0
NUVALENT INC COM 670703107   9,708,236 129,288 SH   SOLE   129,288 0 0
OLEMA PHARMACEUTICALS INC COM 68062P106   7,448,560 658,000 SH   SOLE   658,000 0 0
ORGANOGENESIS HLDGS INC COM 68621F102   27,187,882 9,573,198 SH   SOLE   9,573,198 0 0
ORIC PHARMACEUTICALS INC COM 68622P109   5,788,750 421,000 SH   SOLE   421,000 0 0
PENUMBRA INC COM 70975L107   19,126,526 85,700 SH   SOLE   85,700 0 0
PHARVARIS N V COM N69605108   9,287,932 401,901 SH   SOLE   401,901 0 0
PRAXIS PRECISION MEDICINES I COM NEW 74006W207   2,274,093 37,268 SH   SOLE   37,268 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102   998,085 34,500 SH   SOLE   34,500 0 0
REGULUS THERAPEUTICS INC COM 75915K309   4,500,000 1,562,500 SH   SOLE   1,562,500 0 0
REVOLUTION MEDICINES INC COM 76155X100   23,486,001 728,700 SH   SOLE   728,700 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603   13,678,139 9,241,986 SH   SOLE   9,241,986 0 0
SILK RD MED INC COM 82710M100   183,200 10,000 SH   SOLE   10,000 0 0
SPDR SER TR S&P BIOTECH 78464A870   208,758,000 2,200,000 SH Put SOLE   2,200,000 0 0
SURMODICS INC COM 868873100   23,496,059 800,820 SH   SOLE   800,820 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105   8,782,200 369,000 SH   SOLE   369,000 0 0
TANGO THERAPEUTICS INC COM 87583X109   10,720,151 1,350,145 SH   SOLE   1,350,145 0 0
TAYSHA GENE THERAPIES INC COM SHS 877619106   2,654,750 925,000 SH   SOLE   925,000 0 0
TENAYA THERAPEUTICS INC COM 87990A106   639,221 122,222 SH   SOLE   122,222 0 0
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS 881624209   49,193,668 3,486,440 SH   SOLE   3,486,440 0 0
TG THERAPEUTICS INC COM 88322Q108   48,192,216 3,168,456 SH   SOLE   3,168,456 0 0
THE BEAUTY HEALTH COMPANY COM CL A 88331L108   754,800 170,000 SH   SOLE   170,000 0 0
THERATECHNOLOGIES INC COM NEW 88338H704   7,970,284 4,801,376 SH   SOLE   4,801,376 0 0
TRANSMEDICS GROUP INC COM 89377M109   1,234,798 16,700 SH   SOLE   16,700 0 0
TREACE MED CONCEPTS INC COM 89455T109   17,560,706 1,345,648 SH   SOLE   1,345,648 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102   59,669,540 259,749 SH   SOLE   259,749 0 0
UROGEN PHARMA LTD COM M96088105   150,000 10,000 SH   SOLE   10,000 0 0
VAXCYTE INC COM 92243G108   14,191,403 207,750 SH   SOLE   207,750 0 0
VERASTEM INC COM NEW 92337C203   18,179,481 1,540,634 SH   SOLE   1,540,634 0 0
VIKING THERAPEUTICS INC COM 92686J106   5,503,922 67,121 SH   SOLE   67,121 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104   5,953,400 340,000 SH   SOLE   340,000 0 0
X4 PHARMACEUTICALS INC COM 98420X103   6,366,097 4,579,926 SH   SOLE   4,579,926 0 0
XERIS BIOPHARMA HOLDINGS INC COM 98422E103   137,203 62,083 SH   SOLE   62,083 0 0
Y-MABS THERAPEUTICS INC COM 984241109   9,284,167 570,982 SH   SOLE   570,982 0 0