Cubist Systematic Strategies, LLC Biotechnology

Cubist Systematic Strategies, LLC

$15.6 Billion
Q1 2025

Stock List

Stock	Market Cap.	Holding Value (Reported)	# of Shares.	Last Trade	Trade History
BMEA Biomea Fusion, Inc.	$52.7M	$248,000 0.0% of portfolio	116,687	Q1 2025 Reduced 22.2%
THRD Third Harmonic Bio, Inc.	$220M	$246,000 0.0% of portfolio	70,949	Q1 2025 New
PCVX Vaxcyte, Inc.	$1.95B	$219,000 0.0% of portfolio	5,800	Q1 2025 New
GOSS Gossamer Bio, Inc.	$135M	$213,000 0.0% of portfolio	194,031	Q1 2025 New
FULC Fulcrum Therapeutics, Inc.	$354M	$164,000 0.0% of portfolio	57,070	Q1 2025 New
CVAC Cure Vac N.V.	$1.02B	$141,000 0.0% of portfolio	51,174	Q1 2025 New
PLX Protalix Bio Therapeutics, Inc.	$69.7M	$136,000 0.0% of portfolio	53,380	Q1 2025 Added 82.14%
ZNTL Zentalis Pharmaceuticals, Inc.	$74.1M	$124,000 0.0% of portfolio	78,212	Q1 2025 Reduced 56.6%
PRQR Pro Qr Therapeutics N.V.	$138M	$119,000 0.0% of portfolio	89,645	Q1 2025 Reduced 32.95%
TERN Terns Pharmaceuticals, Inc.	$147M	$78,000 0.0% of portfolio	28,327	Q1 2025 Added 136.77%
SCPH Sc Pharmaceuticals Inc.	$107M	$75,000 0.0% of portfolio	28,759	Q1 2025 New
PHVS Pharvaris N.V.	$607M	$35,000 0.0% of portfolio	2,278	Q1 2025 Reduced 31.71%
IFRX Infla Rx N.V.	$35.4M	$30,000 0.0% of portfolio	30,053	Q1 2025 Added 33.94%
TCRX T Scan Therapeutics, Inc.	$27.3M	$28,000 0.0% of portfolio	20,840	Q1 2025 Reduced 66.97%
VIGL Vigil Neuroscience, Inc.	$224M	$26,000 0.0% of portfolio	15,161	Q1 2025 Reduced 37.14%
TLSA Tiziana Life Sciences LTD	$160M	$24,000 0.0% of portfolio	22,825	Q1 2025 New
CGEN Compugen LTD	$144M	$23,000 0.0% of portfolio	16,062	Q1 2025 Added 45.3%
EPIX Essa Pharma Inc.	$76.2M	$22,000 0.0% of portfolio	14,115	Q1 2025 Reduced 46.3%
SEER Seer, Inc.	$118M	$20,000 0.0% of portfolio	12,172	Q1 2025 Reduced 57.64%
SLN Silence Therapeutics PLC	$200M	$20,000 0.0% of portfolio	7,364	Q1 2025 Reduced 93.07%
ATAI Atai Life Sciences N.V.	$411M	$19,000 0.0% of portfolio	14,680	Q1 2025 New
IMUX Immunic, Inc.	$22.6M	$16,000 0.0% of portfolio	14,742	Q1 2025 Reduced 36.76%
AKBA Akebia Therapeutics, Inc.	$677M	$15,000 0.0% of portfolio	7,835	Q1 2025 New
CLLS Cellectis S.A.	$63.7M	$13,000 0.0% of portfolio	10,859	Q1 2025 New
DMAC Dia Medica Therapeutics Inc.	$95.5M	$12,000 0.0% of portfolio	3,209	Q1 2025 New
IGMS Igm Biosciences, Inc.	$33.9M	$11,000 0.0% of portfolio	9,908	Q1 2025 Reduced 67.14%
ACET Adicet Bio, Inc.	$26.8M	$9,000 0.0% of portfolio	12,398	Q1 2025 Reduced 0.94%
RGLS Regulus Therapeutics Inc.	$120M	$7,000 0.0% of portfolio	4,088	Q1 2025 New
LXRX Lexicon Pharmaceuticals, Inc.	$138M	$6,000 0.0% of portfolio	13,797	Q1 2025 New
SNDX Syndax Pharmaceuticals Inc	$536M	$4,000 0.0% of portfolio	400	Q1 2025 Reduced 99.89%
TECH Bio Techne Corp	$1.96B	$2,000 0.0% of portfolio	39	Q1 2025 New
ENTX Entera Bio Ltd.	$57M	$2,000 0.0% of portfolio	1,560	Q1 2025 New

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