Institutional shares held 112 Million
1M calls
668K puts
Total value of holdings $258M
$2.31M calls
$1.54M puts
Market Cap $289M
124,986,000 Shares Out.
Institutional ownership 89.32%
# of Institutions 100


Latest Institutional Activity in MREO

Top Purchases

Q1 2025
Janus Henderson Group PLC Shares Held: 22.7M ($52.5M)
Q1 2025
Frazier Life Sciences Management, L.P. Shares Held: 7.82M ($18.1M)
Q1 2025
Abrdn PLC Shares Held: 2.19M ($5.06M)
Q1 2025
Schonfeld Strategic Advisors LLC Shares Held: 1.59M ($3.68M)
Q1 2025
Ubs Asset Management Americas Inc Shares Held: 1.57M ($3.62M)

Top Sells

Q1 2025
Adage Capital Partners Gp, L.L.C. Shares Held: 1.7M ($3.93M)
Q1 2025
Millennium Management LLC Shares Held: 394K ($911K)
Q1 2025
Rock Springs Capital Management LP Shares Held: 6.68M ($15.4M)
Q1 2025
Ubs Group Ag Shares Held: 932K ($2.15M)
Q1 2025
Morgan Stanley Shares Held: 2.18M ($5.03M)

About MREO

Mereo BioPharma Group plc, a biopharmaceutical company, develops and commercializes therapeutics for the treatment of oncology and rare diseases in the United Kingdom and internationally. Its lead product candidate, etigilimab (OMP-313M32), an antibody T-cell immunoreceptor with Ig and ITIM domains, which is in Phase 1b clinical trial for the treatment of tumor. The company is also developing Navicixizumab (OMP-305B83), which has completed Phase 1b clinical trials for the treatment of the late line ovarian cancer; Acumapimod (BCT-197), a p38 MAP kinase inhibitor that is in Phase II clinical trials to treat acute exacerbations of chronic obstructive pulmonary disease; and Leflutrozole (BGS-649), an oral aromatase inhibitor for the treatment of hypogonadotropic hypogonadism. In addition, it develops rare disease product candidates, including Setrusumab (BPS-804), a novel antibody for the treatment of osteogenesis imperfecta; and Alvelestat (MPH-966), an oral small molecule that is in Phase II clinical trial to treat Alpha-1 antitrypsin deficiency. The company has a collaboration with The University of Texas MD Anderson Cancer Center to evaluate anti-TIGIT therapeutic antibody candidate, etigilimab. Mereo BioPharma Group plc was incorporated in 2015 and is based in London, the United Kingdom.


Insider Transactions at MREO

Insider Transaction List

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Date Insider Transaction Ownership Type Shares Traded Value / Price
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Last 12 Months Summary

Buy / Acquisition
1.31M Shares
From 8 Insiders
Grant, award, or other acquisition 37.6K shares
Exercise of conversion of derivative security 1.27M shares
Sell / Disposition
697K Shares
From 6 Insiders
Open market or private sale 697K shares

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