Institutional shares held 98.2 Million
2.28M calls
761K puts
Total value of holdings $163M
$3.79M calls
$1.26M puts
Market Cap $207M
124,986,000 Shares Out.
Institutional ownership 78.59%
# of Institutions 97


Latest Institutional Activity in MREO

Top Purchases

Q2 2025
Frazier Life Sciences Management, L.P. Shares Held: 9.44M ($15.7M)
Q2 2025
Goldman Sachs Group Inc Shares Held: 3.09M ($5.13M)
Q2 2025
Abrdn PLC Shares Held: 3.03M ($5.03M)
Q2 2025
Citadel Advisors LLC Shares Held: 761K ($1.26M)
Q2 2025
Two Sigma Investments, LP Shares Held: 659K ($1.09M)

Top Sells

Q2 2025
Janus Henderson Group PLC Shares Held: 17.7M ($29.4M)
Q2 2025
Rock Springs Capital Management LP Shares Held: 4.47M ($7.41M)
Q2 2025
Morgan Stanley Shares Held: 785K ($1.3M)
Q2 2025
Schonfeld Strategic Advisors LLC Shares Held: 910K ($1.51M)
Q2 2025
Ubs Group Ag Shares Held: 374K ($620K)

About MREO

Mereo BioPharma Group plc, a biopharmaceutical company, develops and commercializes therapeutics for the treatment of oncology and rare diseases in the United Kingdom and internationally. Its lead product candidate, etigilimab (OMP-313M32), an antibody T-cell immunoreceptor with Ig and ITIM domains, which is in Phase 1b clinical trial for the treatment of tumor. The company is also developing Navicixizumab (OMP-305B83), which has completed Phase 1b clinical trials for the treatment of the late line ovarian cancer; Acumapimod (BCT-197), a p38 MAP kinase inhibitor that is in Phase II clinical trials to treat acute exacerbations of chronic obstructive pulmonary disease; and Leflutrozole (BGS-649), an oral aromatase inhibitor for the treatment of hypogonadotropic hypogonadism. In addition, it develops rare disease product candidates, including Setrusumab (BPS-804), a novel antibody for the treatment of osteogenesis imperfecta; and Alvelestat (MPH-966), an oral small molecule that is in Phase II clinical trial to treat Alpha-1 antitrypsin deficiency. The company has a collaboration with The University of Texas MD Anderson Cancer Center to evaluate anti-TIGIT therapeutic antibody candidate, etigilimab. Mereo BioPharma Group plc was incorporated in 2015 and is based in London, the United Kingdom.


Insider Transactions at MREO

Insider Transaction List

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Date Insider Transaction Ownership Type Shares Traded Value / Price
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Last 12 Months Summary

Buy / Acquisition
673K Shares
From 6 Insiders
Exercise of conversion of derivative security 673K shares
Sell / Disposition
417K Shares
From 6 Insiders
Open market or private sale 417K shares

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