David A. Siegel Omeros Corp Transaction History

Two Sigma Advisers, LP

$47 Billion
Q3 2025

A detailed history of David A. Siegel (Two Sigma Advisers, LP) transactions in Omeros Corp stock. As of the latest transaction made, Two Sigma Advisers, LP holds 578,200 shares of OMER stock, worth $4.28 Million. This represents 0.01% of its overall portfolio holdings.

Number of Shares

578,200

Previous 422,800 36.75%

Holding current value

$4.28 Million

Previous $1.27 Million 86.91%

% of portfolio

0.01%

Previous 0.0%

28 transactions

Quarter	Operation	Price Per share	shares change	shares Held
Q3 2025 Nov 14, 2025	BUY	$3.06 - $4.48 $475,524 - $696,192	155,400 Added 36.75%	578,200 $2.37 Million
Q2 2025 Aug 14, 2025	BUY	$3.0 - $8.01 $1.22 Million - $3.26 Million	407,300 Added 2627.74%	422,800 $1.27 Million
Q1 2025 May 15, 2025	SELL	$7.04 - $11.21 $164,032 - $261,193	-23,300 Reduced 60.05%	15,500 $127,000
Q4 2024 Feb 14, 2025	SELL	$3.77 - $12.15 $27,144 - $87,480	-7,200 Reduced 15.65%	38,800 $383,000
Q3 2024 Nov 14, 2024	SELL	$3.54 - $5.47 $116,820 - $180,510	-33,000 Reduced 41.77%	46,000 $182,000

Q2 2024 Aug 14, 2024	BUY	$3.04 - $4.23 $133,152 - $185,274	43,800 Added 124.43%	79,000 $320,000
Q1 2024 May 15, 2024	BUY	$2.88 - $4.89 $40,608 - $68,949	14,100 Added 66.82%	35,200 $121,000
Q4 2023 Feb 14, 2024	SELL	$1.08 - $3.63 $31,104 - $104,544	-28,800 Reduced 57.72%	21,100 $68,000
Q3 2023 Nov 14, 2023	BUY	$2.81 - $5.69 $31,753 - $64,297	11,300 Added 29.27%	49,900 $145,000
Q2 2023 Aug 14, 2023	SELL	$4.45 - $7.57 $173,995 - $295,987	-39,100 Reduced 50.32%	38,600 $209,000
Q1 2023 May 15, 2023	SELL	$2.48 - $5.22 $321,656 - $677,034	-129,700 Reduced 62.54%	77,700 $361,000
Q4 2022 Feb 14, 2023	SELL	$1.75 - $3.96 $56,175 - $127,116	-32,100 Reduced 13.4%	207,400 $468,000
Q3 2022 Nov 14, 2022	SELL	$3.09 - $7.46 $421,167 - $1.02 Million	-136,300 Reduced 36.27%	239,500 $754,000
Q2 2022 Aug 15, 2022	BUY	$1.92 - $6.28 $515,712 - $1.69 Million	268,600 Added 250.56%	375,800 $1.03 Million
Q1 2022 May 16, 2022	SELL	$5.07 - $7.2 $95,823 - $136,080	-18,900 Reduced 14.99%	107,200 $644,000
Q4 2021 Feb 14, 2022	SELL	$5.67 - $8.54 $241,542 - $363,803	-42,600 Reduced 25.25%	126,100 $811,000
Q3 2021 Nov 15, 2021	BUY	$13.4 - $16.3 $493,120 - $599,840	36,800 Added 27.9%	168,700 $2.33 Million
Q2 2021 Aug 16, 2021	BUY	$14.81 - $19.13 $962,650 - $1.24 Million	65,000 Added 97.16%	131,900 $1.96 Million
Q1 2021 May 17, 2021	BUY	$14.52 - $23.53 $971,388 - $1.57 Million	66,900 New	66,900 $1.19 Million
Q3 2020 Nov 16, 2020	SELL	$9.57 - $21.32 $397,155 - $884,780	-41,500 Closed	0 $0
Q2 2020 Aug 14, 2020	BUY	$12.21 - $16.99 $180,708 - $251,451	14,800 Added 55.43%	41,500 $611,000
Q1 2020 May 15, 2020	BUY	$9.03 - $19.72 $241,100 - $526,524	26,700 New	26,700 $357,000
Q3 2019 Nov 14, 2019	SELL	$14.55 - $20.56 $558,720 - $789,504	-38,400 Closed	0 $0
Q2 2019 Aug 14, 2019	SELL	$15.0 - $19.62 $325,500 - $425,754	-21,700 Reduced 36.11%	38,400 $602,000
Q1 2019 May 15, 2019	BUY	$11.65 - $17.72 $239,990 - $365,032	20,600 Added 52.15%	60,100 $1.04 Million
Q4 2018 Feb 14, 2019	BUY	$10.72 - $16.73 $189,744 - $296,121	17,700 Added 81.19%	39,500 $440,000
Q3 2018 Nov 14, 2018	SELL	$17.73 - $26.69 $58,509 - $88,077	-3,300 Reduced 13.15%	21,800 $532,000
Q2 2018 Aug 14, 2018	BUY	$10.79 - $24.44 $270,829 - $613,444	25,100 New	25,100 $455,000

Others Institutions Holding OMER

# of Institutions

155

Shares Held

33.1M

Call Options Held

2.2M

Put Options Held

2.72M

View Full List

About OMEROS CORP

Ticker OMER
Exchange NASDAQ
Sector Healthcare
Industry Biotechnology
Shares Outstandng 62,730,000
Market Cap $465M
Description
Omeros Corporation, a commercial-stage biopharmaceutical company, discovers, develops, and commercializes small-molecule and protein therapeutics, and orphan indications targeting inflammation, complement-mediated diseases, cancers related to dysfunction of the immune system, and addictive and compulsive disorders. The company's clinical program...

More about OMER

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