David A. Siegel Opko Health, Inc. Transaction History

Two Sigma Advisers, LP

$47 Billion
Q3 2025

A detailed history of David A. Siegel (Two Sigma Advisers, LP) transactions in Opko Health, Inc. stock. As of the latest transaction made, Two Sigma Advisers, LP holds 344,097 shares of OPK stock, worth $440,444. This represents 0.0% of its overall portfolio holdings.

Number of Shares

344,097

Previous 648,297 46.92%

Holding current value

$440,444

Previous $855,000 37.66%

% of portfolio

0.0%

Previous 0.0%

27 transactions

Quarter	Operation	Price Per share	shares change	shares Held
Q3 2025 Nov 14, 2025	SELL	$1.19 - $1.55 $361,998 - $471,510	-304,200 Reduced 46.92%	344,097 $533,000
Q2 2025 Aug 14, 2025	BUY	$1.24 - $1.66 $119,784 - $160,356	96,600 Added 17.51%	648,297 $855,000
Q1 2025 May 15, 2025	BUY	$1.45 - $1.94 $247,225 - $330,770	170,500 Added 44.73%	551,697 $915,000
Q4 2024 Feb 14, 2025	BUY	$1.4 - $1.64 $11,754 - $13,769	8,396 Added 2.25%	381,197 $560,000
Q3 2024 Nov 14, 2024	SELL	$1.21 - $1.68 $108,416 - $150,528	-89,600 Reduced 19.38%	372,801 $555,000

Q2 2024 Aug 14, 2024	SELL	$1.21 - $1.42 $883,779 - $1.04 Million	-730,396 Reduced 61.23%	462,401 $578,000
Q1 2024 May 15, 2024	BUY	$0.87 - $1.57 $48,633 - $87,763	55,900 Added 4.92%	1,192,797 $1.43 Million
Q4 2023 Feb 14, 2024	SELL	$1.23 - $1.63 $216,726 - $287,206	-176,200 Reduced 13.42%	1,136,897 $1.72 Million
Q3 2023 Nov 14, 2023	SELL	$1.5 - $2.17 $189,150 - $273,637	-126,100 Reduced 8.76%	1,313,097 $2.1 Million
Q2 2023 Aug 14, 2023	SELL	$1.37 - $2.17 $490,597 - $777,077	-358,100 Reduced 19.92%	1,439,197 $3.12 Million
Q1 2023 May 15, 2023	SELL	$1.06 - $1.61 $493,642 - $749,777	-465,700 Reduced 20.58%	1,797,297 $2.62 Million
Q4 2022 Feb 14, 2023	BUY	$1.05 - $2.01 $147,630 - $282,605	140,600 Added 6.62%	2,262,997 $2.83 Million
Q3 2022 Nov 14, 2022	BUY	$1.81 - $2.81 $2.31 Million - $3.58 Million	1,275,600 Added 150.64%	2,122,397 $4.01 Million
Q2 2022 Aug 15, 2022	BUY	$2.33 - $3.61 $1.18 Million - $1.82 Million	504,597 Added 147.46%	846,797 $2.14 Million
Q1 2022 May 16, 2022	BUY	$2.87 - $4.93 $174,783 - $300,237	60,900 Added 21.65%	342,200 $1.18 Million
Q4 2021 Feb 14, 2022	BUY	$3.52 - $5.15 $918,720 - $1.34 Million	261,000 Added 1285.71%	281,300 $1.35 Million
Q3 2021 Nov 15, 2021	SELL	$3.44 - $4.24 $318,544 - $392,624	-92,600 Reduced 82.02%	20,300 $74,000
Q2 2021 Aug 16, 2021	SELL	$3.33 - $4.55 $253,080 - $345,800	-76,000 Reduced 40.23%	112,900 $457,000
Q1 2021 May 17, 2021	BUY	$4.19 - $5.99 $791,491 - $1.13 Million	188,900 New	188,900 $810,000
Q3 2020 Nov 16, 2020	SELL	$2.99 - $5.96 $2.72 Million - $5.42 Million	-908,632 Closed	0 $0
Q2 2020 Aug 14, 2020	SELL	$1.15 - $3.41 $367,655 - $1.09 Million	-319,700 Reduced 26.03%	908,632 $3.1 Million
Q1 2020 May 15, 2020	BUY	$1.34 - $2.32 $1.06 Million - $1.84 Million	793,227 Added 182.31%	1,228,332 $1.65 Million
Q4 2019 Feb 14, 2020	BUY	$1.42 - $2.17 $617,849 - $944,177	435,105 New	435,105 $640,000
Q3 2019 Nov 14, 2019	SELL	$1.75 - $2.47 $24,543 - $34,641	-14,025 Closed	0 $0
Q2 2019 Aug 14, 2019	BUY	$1.79 - $2.61 $25,104 - $36,605	14,025 New	14,025 $34,000
Q1 2019 May 15, 2019	SELL	$2.42 - $3.83 $39,688 - $62,812	-16,400 Closed	0 $0
Q4 2018 Feb 14, 2019	BUY	$2.46 - $3.87 $40,344 - $63,468	16,400 New	16,400 $49,000

Others Institutions Holding OPK

# of Institutions

255

Shares Held

194M

Call Options Held

1.68M

Put Options Held

126K

View Full List

About OPKO HEALTH, INC.

Ticker OPK
Exchange NASDAQ
Sector Healthcare
Industry Diagnostics & Research
Shares Outstandng 771,960,000
Market Cap $988M
Description
OPKO Health, Inc., a healthcare company, engages in the diagnostics and pharmaceuticals businesses in the United States, Ireland, Chile, Spain, Israel, Mexico, and internationally. The company's Diagnostics segment operates BioReference Laboratories that offers laboratory testing services for the detection, diagnosis, evaluation, monitoring, and...

More about OPK

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