David A. Siegel Pro Qr Therapeutics N.V. Transaction History

Two Sigma Advisers, LP

$47 Billion
Q3 2025

A detailed history of David A. Siegel (Two Sigma Advisers, LP) transactions in Pro Qr Therapeutics N.V. stock. As of the latest transaction made, Two Sigma Advisers, LP holds 228,600 shares of PRQR stock, worth $500,634. This represents 0.0% of its overall portfolio holdings.

Number of Shares

228,600

Previous 140,300 62.94%

Holding current value

$500,634

Previous $286,000 68.53%

% of portfolio

0.0%

Previous 0.0%

19 transactions

Quarter	Operation	Price Per share	shares change	shares Held
Q3 2025 Nov 14, 2025	BUY	$1.89 - $2.48 $166,887 - $218,984	88,300 Added 62.94%	228,600 $482,000
Q2 2025 Aug 14, 2025	BUY	$1.12 - $2.16 $88,816 - $171,288	79,300 Added 130.0%	140,300 $286,000
Q1 2025 May 15, 2025	BUY	$1.33 - $2.77 $42,294 - $88,086	31,800 Added 108.9%	61,000 $81,000
Q4 2024 Feb 14, 2025	SELL	$1.81 - $4.49 $105,523 - $261,767	-58,300 Reduced 66.63%	29,200 $79,000
Q3 2024 Nov 14, 2024	SELL	$1.64 - $2.24 $72,160 - $98,560	-44,000 Reduced 33.46%	87,500 $159,000

Q2 2024 Aug 14, 2024	SELL	$1.65 - $2.39 $50,325 - $72,895	-30,500 Reduced 18.83%	131,500 $218,000
Q1 2024 May 15, 2024	SELL	$1.89 - $2.85 $12,663 - $19,095	-6,700 Reduced 3.97%	162,000 $370,000
Q4 2023 Feb 14, 2024	SELL	$1.15 - $2.21 $68,425 - $131,495	-59,500 Reduced 26.07%	168,700 $334,000
Q3 2023 Nov 14, 2023	SELL	$1.3 - $1.77 $302,900 - $412,410	-233,000 Reduced 50.52%	228,200 $296,000
Q2 2023 Aug 14, 2023	BUY	$1.62 - $2.32 $141,264 - $202,304	87,200 Added 23.32%	461,200 $747,000
Q1 2023 May 15, 2023	BUY	$1.99 - $3.66 $243,775 - $448,350	122,500 Added 48.71%	374,000 $796,000
Q4 2022 Feb 14, 2023	BUY	$0.8 - $3.7 $62,560 - $289,340	78,200 Added 45.12%	251,500 $930,000
Q3 2022 Nov 14, 2022	BUY	$0.74 - $0.89 $86,876 - $104,486	117,400 Added 210.02%	173,300 $129,000
Q2 2022 Aug 15, 2022	SELL	$0.56 - $1.0 $42,448 - $75,800	-75,800 Reduced 57.56%	55,900 $43,000
Q1 2022 May 16, 2022	BUY	$0.9 - $8.39 $118,530 - $1.1 Million	131,700 New	131,700 $119,000
Q4 2021 Feb 14, 2022	SELL	$6.58 - $8.44 $83,566 - $107,188	-12,700 Closed	0 $0
Q3 2021 Nov 15, 2021	BUY	$5.16 - $8.47 $65,532 - $107,569	12,700 New	12,700 $106,000
Q3 2020 Nov 16, 2020	SELL	$4.79 - $6.3 $65,144 - $85,680	-13,600 Closed	0 $0
Q2 2020 Aug 14, 2020	BUY	$4.5 - $6.53 $61,200 - $88,808	13,600 New	13,600 $83,000

Others Institutions Holding PRQR

# of Institutions

Shares Held

38.3M

Call Options Held

Put Options Held

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About ProQR Therapeutics N.V.

Ticker PRQR
Exchange NASDAQ
Sector Healthcare
Industry Biotechnology
Shares Outstandng 71,362,096
Market Cap $156M
Description
ProQR Therapeutics N.V., a biopharmaceutical company, engages in the discovery and development of RNA-based therapeutics for the treatment of genetic disorders. It primarily develops sepofarsen that is in phase II/III clinical trial illuminate trial for treating leber congenital amaurosis 10 disease; and ultevursen, which is in phase II/III clin...

More about PRQR

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