Jim Simons Medical Devices

Renaissance Technologies LLC

$70.6 Billion
Q3 2025

Stock List

Stock	Market Cap.	Holding Value (Reported)	# of Shares.	Last Trade
PODD Insulet Corp	$23.1B	$121 Million 0.17% of portfolio	390,893	Q3 2025 Added 4.45%
BSX Boston Scientific Corp	$147B	$89.5 Million 0.13% of portfolio	917,105	Q3 2025 Reduced 38.72%
DXCM Dexcom Inc	$22.4B	$56.6 Million 0.08% of portfolio	841,564	Q3 2025 Added 20.6%
SYK Stryker Corp	$136B	$38.1 Million 0.05% of portfolio	103,200	Q3 2025 New
UFPT Ufp Technologies Inc	$1.75B	$37.8 Million 0.05% of portfolio	189,259	Q3 2025 Reduced 18.86%
INMD In Mode Ltd.	$1.18B	$36.6 Million 0.05% of portfolio	2,454,518	Q3 2025 Added 5.5%
IRMD Iradimed Corp	$1.06B	$34.8 Million 0.05% of portfolio	488,762	Q3 2025 Reduced 0.62%
IRTC I Rhythm Technologies, Inc.	$5.13B	$20.9 Million 0.03% of portfolio	121,400	Q3 2025 Reduced 14.02%
STE Steris PLC	$25.8B	$19.7 Million 0.03% of portfolio	79,808	Q3 2025 Added 223.0%
TMDX Trans Medics Group, Inc.	$3.66B	$16.3 Million 0.02% of portfolio	145,199	Q3 2025 New
ATEC Alphatec Holdings, Inc.	$2.07B	$14.2 Million 0.02% of portfolio	979,000	Q3 2025 Added 31.55%
GMED Globus Medical Inc	$6.51B	$14 Million 0.02% of portfolio	243,918	Q3 2025 Added 131.38%
ZBH Zimmer Biomet Holdings, Inc.	$18.9B	$12 Million 0.02% of portfolio	121,800	Q3 2025 New
INSP Inspire Medical Systems, Inc.	$2.49B	$11.5 Million 0.02% of portfolio	155,000	Q3 2025 Added 22.24%
LIVN Liva Nova PLC	$2.96B	$10.2 Million 0.01% of portfolio	194,594	Q3 2025 Added 2.58%
SIBN Si Bone, Inc.	$598M	$7.36 Million 0.01% of portfolio	499,700	Q3 2025 Added 19.06%
BVS Bioventus Inc.	$453M	$5.43 Million 0.01% of portfolio	811,200	Q3 2025 Added 2.58%
ELMD Electromed, Inc.	$214M	$5.26 Million 0.01% of portfolio	216,904	Q3 2025 Added 7.27%
TCMD Tactile Systems Technology Inc	$481M	$5.02 Million 0.01% of portfolio	365,200	Q3 2025 Reduced 0.22%
ANIK Anika Therapeutics, Inc.	$145M	$5.01 Million 0.01% of portfolio	533,017	Q3 2025 Added 1.1%
INGN Inogen Inc	$158M	$4.83 Million 0.01% of portfolio	591,400	Q3 2025 Reduced 18.55%
GKOS Glaukos Corp	$4.29B	$4.72 Million 0.01% of portfolio	57,892	Q3 2025 New
BWAY Brainsway Ltd.	$262M	$4.67 Million 0.01% of portfolio	313,160	Q3 2025 Added 10.32%
FONR Fonar Corp	$98.2M	$4.67 Million 0.01% of portfolio	308,616	Q3 2025 Reduced 2.19%
BRKR Bruker Corp	$6.17B	$4.54 Million 0.01% of portfolio	139,610	Q3 2025 Reduced 20.59%
ARAY Accuray Inc	$100M	$4.02 Million 0.01% of portfolio	2,484,284	Q3 2025 Reduced 4.61%
ITGR Integer Holdings Corp	$2.3B	$3.36 Million 0.0% of portfolio	32,500	Q3 2025 New
VREX Varex Imaging Corp	$476M	$3.28 Million 0.0% of portfolio	264,900	Q3 2025 Reduced 13.2%
VMD Viemed Healthcare, Inc.	$244M	$2.98 Million 0.0% of portfolio	447,000	Q3 2025 Added 8.94%
CTKB Cytek Biosciences, Inc.	$740M	$2.76 Million 0.0% of portfolio	795,544	Q3 2025 Reduced 25.17%
DCTH Delcath Systems, Inc.	$76.8M	$2.75 Million 0.0% of portfolio	256,200	Q3 2025 Added 43.93%
AHCO Adapt Health Corp.	$1.24B	$1.99 Million 0.0% of portfolio	222,865	Q3 2025 Reduced 1.5%
TNDM Tandem Diabetes Care Inc	$1.2B	$1.96 Million 0.0% of portfolio	161,500	Q3 2025 Reduced 52.82%
ZIMV Zim Vie Inc.	$495M	$1.94 Million 0.0% of portfolio	102,500	Q3 2025 Reduced 75.51%
MASS 908 Devices Inc.	$173M	$1.83 Million 0.0% of portfolio	209,300	Q3 2025 Added 20.22%
OFIX Orthofix Medical Inc.	$299M	$1.41 Million 0.0% of portfolio	96,091	Q3 2025 Reduced 79.52%
NPCE Neuro Pace Inc	$319M	$1.35 Million 0.0% of portfolio	129,100	Q3 2025 Reduced 0.01%
CERS Cerus Corp	$287M	$1.33 Million 0.0% of portfolio	839,500	Q3 2025 Added 9.67%
SGHT Sight Sciences, Inc.	$340M	$1.29 Million 0.0% of portfolio	375,800	Q3 2025 Reduced 17.41%
RXST Rx Sight, Inc.	$269M	$1.25 Million 0.0% of portfolio	138,700	Q3 2025 Reduced 67.47%
MXCT Maxcyte, Inc.	$161M	$1.19 Million 0.0% of portfolio	750,776	Q3 2025 Added 4.59%
AVNS Avanos Medical, Inc.	$529M	$907,000 0.0% of portfolio	78,500	Q3 2025 Reduced 18.9%
SRTS Sensus Healthcare, Inc.	$71.5M	$819,000 0.0% of portfolio	261,134	Q3 2025 Added 4.4%
QIPT Quipt Home Medical Corp.	$81.1M	$807,000 0.0% of portfolio	310,500	Q3 2025 Added 14.53%
SENS Senseonics Holdings, Inc.	$2.91B	$748,000 0.0% of portfolio	1,701,744	Q3 2025 Reduced 38.23%
MYO Myomo, Inc.	$5.74M	$633,000 0.0% of portfolio	712,094	Q3 2025 Added 31.53%
NMTC Neuroone Medical Technologies Corp	$11.2M	$616,000 0.0% of portfolio	692,600	Q3 2025 Added 47.71%
LUNG Pulmonx Corp	$55.5M	$539,000 0.0% of portfolio	332,810	Q3 2025 Added 32.43%
APYX Apyx Medical Corp	$134M	$474,000 0.0% of portfolio	221,697	Q3 2025 Added 22.22%
IRIX Iridex Corp	$15.7M	$447,000 0.0% of portfolio	389,060	Q3 2025 Added 2.72%

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Jim Simons

Jim Simons is the founder and chairman of Renaissance Technologies, a successful investment firm that uses quantitative approaches to investing. Simons is known for his expertise in mathematical modeling and has a reputation for being a skilled and successful investor. He has generated strong returns for his clients over the long term.

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