Sio Capital Management, LLC Portfolio Holdings

Sio Capital Management, LLC

  • $209 Million
  • Q2 2025

Sio Capital Management, LLC has filed its 13F form on August 13, 2025 for Q2 2025 where it was disclosed a total value porftolio of $209 Million distributed in 52 stocks.

Among their holdings, we can observe that their the top five positions include companies like: Maximus, Inc. with a value of $38.5M, Globus Medical Inc with a value of $14.5M, Centene Corp with a value of $14.2M, Merck & Co., Inc. with a value of $13.8M, and Neurocrine Biosciences Inc with a value of $12.7M.

Examining the 13F form we can see an decrease of $56.6M in the current position value, from $266M to 209M.

Sio Capital Management, LLC is based out at New York, NY

Below you can find more details about Sio Capital Management, LLC portfolio as well as his latest detailed transactions.

Portfolio value $209 Million
Healthcare: $171 Million
Industrials: $38.5 Million

Stock Holdings Table

Stock Market Cap. Holding Value (Reported) # of Shares. Last Trade Trade History
$5.36B
$38.5 Million 18.38% of portfolio
548,086
Q2 2025 Added 17.02%
$4.33B
$14.5 Million 6.93% of portfolio
245,570
Q2 2025 Added 18.63%
$18.1B
$14.2 Million 6.81% of portfolio
262,500
Q2 2025 New
$206B
$13.8 Million 6.58% of portfolio
173,951
Q2 2025 Reduced 35.72%
$13.7B
$12.7 Million 6.05% of portfolio
100,725
Q2 2025 Reduced 46.3%
$10.1B
$12.4 Million 5.91% of portfolio
225,114
Q2 2025 Added 59.5%
$124M
$9.83 Million 4.7% of portfolio
4,095,764
Q2 2025 Added 20.54%
$118B
$9.06 Million 4.33% of portfolio
187,500
Q2 2025 New
$517M
$7.75 Million 3.71% of portfolio
810,274
Q2 2025 Added 94.49%
$1.72B
$7.37 Million 3.52% of portfolio
112,923
Q2 2025 Added 29.35%
$865M
$7.08 Million 3.38% of portfolio
539,730
Q2 2025 New
$1.59B
$4.94 Million 2.36% of portfolio
158,736
Q2 2025 Added 30.99%
$138M
$4.23 Million 2.02% of portfolio
2,075,139
Q2 2025 Added 1.0%
$52M
$3.96 Million 1.89% of portfolio
3,735,396
Q1 2025 Added 4.57%
$551M
$3.54 Million 1.69% of portfolio
288,849
Q2 2025 Added 1.0%
$3.12B
$3.3 Million 1.58% of portfolio
62,719
Q2 2025 New
$130M
$2.8 Million 1.34% of portfolio
1,307,964
Q2 2025 Reduced 49.36%
$1.18B
$2.61 Million 1.25% of portfolio
124,230
Q2 2025 Added 1.0%
$637M
$2.41 Million 1.15% of portfolio
478,343
Q2 2025 Added 1.0%
$14.4M
$2.4 Million 1.14% of portfolio
3,523,663
Q2 2025 New
$209M
$2.33 Million 1.11% of portfolio
4,852,298
Q2 2025 New
$1.52B
$1.81 Million 0.86% of portfolio
122,210
Q2 2025 Added 1.0%
$195M
$1.74 Million 0.83% of portfolio
1,369,748
Q2 2025 Added 1.0%
$110M
$1.71 Million 0.81% of portfolio
318,256
Q2 2025 Added 1.0%
$414M
$1.66 Million 0.79% of portfolio
726,851
Q2 2025 Added 1.0%
$155M
$1.35 Million 0.65% of portfolio
178,774
Q2 2025 Added 1.0%
$30.8M
$1.23 Million 0.59% of portfolio
636,300
Q2 2025 Added 1.0%
$244M
$1.18 Million 0.57% of portfolio
845,531
Q2 2025 Added 1.0%
$13.3M
$885,000 0.42% of portfolio
1,341,636
Q2 2025 Added 1.0%
$90.8M
$736,000 0.35% of portfolio
2,232,000
Q1 2025 Added 123.2%
$7.53M
$581,000 0.28% of portfolio
785,824
Q2 2025 Added 211.85%
$208M
$577,000 0.28% of portfolio
122,889
Q2 2025 Added 1.0%
$872M
$302,000 0.14% of portfolio
31,169
Q2 2025 Reduced 97.19%
$160M
$60,000 0.03% of portfolio
131,300
Q2 2025 Added 1.0%
$285M
$37,000 0.02% of portfolio
10,100
Q2 2025 Added 1.0%
$0
$19,000 0.01% of portfolio
49,998
Q1 2023 New
Avalo Therapeutics Inc
-
$0 0.0% of portfolio
-
Q2 2025 Added 1.0%
Aprea Therapeutics Inc
-
$0 0.0% of portfolio
-
Q2 2025 Added 1.0%
Anteris Technologies Global
-
$0 0.0% of portfolio
-
Q2 2025 Reduced 22.4%
Aligos Therapeutics Inc
-
$0 0.0% of portfolio
-
Q2 2025 Added 85.89%
Mbx Biosciences Inc
-
$0 0.0% of portfolio
-
Q2 2025 New
Boundless Bio Inc
-
$0 0.0% of portfolio
-
Q2 2025 Added 1.0%
Bright Minds Biosciences Inc
-
$0 0.0% of portfolio
-
Q2 2025 Added 0.94%
Rocket Pharmaceuticals Inc
-
$0 0.0% of portfolio
-
Q1 2023 New
Dianthus Therapeutics Inc
-
$0 0.0% of portfolio
-
Q2 2025 Added 101.77%
Disc Medicine Inc
-
$0 0.0% of portfolio
-
Q2 2025 Added 287.41%
Nyxoah S A
-
$0 0.0% of portfolio
-
Q1 2024 Reduced 74.59%
Septerna Inc
-
$0 0.0% of portfolio
-
Q2 2025 Reduced 25.9%

Summary

  • Portfolio
  • No. of Stocks 52
  • Current Value $209 Million
  • Prior Value $266 Million
  • Filing
  • Period Q2 2025
  • Filing Date August 13, 2025
  • Form Type 13F-HR
  • Activity in Q2 2025
  • New Purchases 7 stocks
  • Additional Purchases 31 stocks
  • Sold out of 0 stocks
  • Reduced holdings in 6 stocks
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