Soleus Capital Management, L.P. Portfolio Holdings

Soleus Capital Management, L.P.

  • $1.64 Billion
  • Q3 2025

Soleus Capital Management, L.P. has filed its 13F form on November 14, 2025 for Q3 2025 where it was disclosed a total value porftolio of $1.64 Billion distributed in 88 stocks.

Among their holdings, we can observe that their the top five positions include companies like: Krystal Biotech, Inc. with a value of $180M, Tg Therapeutics, Inc. with a value of $139M, Novo Cure LTD with a value of $125M, Elevance Health, Inc. with a value of $83.9M, and United Therapeutics Corp with a value of $62.9M.

Examining the 13F form we can see an increase of $354M in the current position value, from $1.29B to 1.64B.

Soleus Capital Management, L.P. is based out at Greenwich, CT

Below you can find more details about Soleus Capital Management, L.P. portfolio as well as his latest detailed transactions.

Portfolio value $1.64 Billion
Healthcare: $1.53 Billion
ETFs: $115 Million

Stock Holdings Table

Stock Market Cap. Holding Value (Reported) # of Shares. Last Trade Trade History
$5.29B
$180 Million 10.94% of portfolio
1,018,831
Q3 2025 Added 10.39%
$4.5B
$139 Million 8.45% of portfolio
3,844,731
Q3 2025 Added 71.34%
$1.19B
$125 Million 7.58% of portfolio
9,644,872
Q3 2025 Added 39.69%
$78.2B
$83.9 Million 5.1% of portfolio
259,650
Q3 2025 Added 270.93%
$21.2B
$62.9 Million 3.82% of portfolio
150,000
Q3 2025 Reduced 28.5%
$846M
$61.8 Million 3.76% of portfolio
8,127,100
Q3 2025 Reduced 0.49%
$1.38B
$57.9 Million 3.52% of portfolio
1,178,860
Q3 2025 Reduced 60.86%
$593M
$55 Million 3.34% of portfolio
12,131,699
Q3 2025 Reduced 1.71%
$2.49B
$54 Million 3.29% of portfolio
728,188
Q3 2025 Added 568.06%
$1.51B
$52.5 Million 3.19% of portfolio
1,866,234
Q3 2025 Added 426.59%
$50.2B
$51.2 Million 3.11% of portfolio
69,426
Q3 2025 Added 61.92%
$10.2B
$48.2 Million 2.93% of portfolio
890,304
Q3 2025 Reduced 1.33%
$2.66B
$37 Million 2.25% of portfolio
4,690,000
Q3 2025 New
$9.05B
$31.3 Million 1.91% of portfolio
68,336
Q3 2025 Added 754.2%
$1.46B
$31.2 Million 1.9% of portfolio
340,243
Q3 2025 Added 570.52%
$319M
$30.9 Million 1.88% of portfolio
2,957,957
Q3 2025 Added 27.89%
$1B
$30.8 Million 1.87% of portfolio
1,726,553
Q3 2025 Added 18.31%
$5.91B
$24.9 Million 1.51% of portfolio
2,500,000
Q3 2025 Reduced 56.57%
$423M
$23.7 Million 1.44% of portfolio
17,290,000
Q3 2025 Added 7.13%
$603M
$22.4 Million 1.36% of portfolio
2,422,833
Q1 2025 Added 15.22%
$981M
$20.6 Million 1.26% of portfolio
1,440,818
Q3 2025 Added 3.82%
$13.9B
$19.4 Million 1.18% of portfolio
138,000
Q3 2025 New
$75.2M
$16.4 Million 1.0% of portfolio
7,309,254
Q3 2024 Added 0.21%
$795M
$16.1 Million 0.98% of portfolio
647,052
Q3 2025 Reduced 11.72%
$1.88B
$15.7 Million 0.95% of portfolio
497,953
Q3 2025 Added 877.28%
$121M
$15.7 Million 0.95% of portfolio
7,053,942
Q3 2025 Added 1.07%
$2.9B
$15.5 Million 0.94% of portfolio
210,000
Q3 2025 New
$2.82B
$14.5 Million 0.88% of portfolio
422,055
Q3 2025 Reduced 41.01%
$1.26B
$13.4 Million 0.82% of portfolio
500,000
Q3 2025 Reduced 83.25%
$553M
$13.3 Million 0.81% of portfolio
679,000
Q3 2025 Reduced 68.92%
$1.4B
$11.7 Million 0.71% of portfolio
200,000
Q3 2025 New
$1.43B
$11 Million 0.67% of portfolio
375,000
Q3 2025 Added 115.52%
$2.63B
$10.9 Million 0.66% of portfolio
148,696
Q3 2025 Reduced 50.22%
$3.06B
$10.8 Million 0.66% of portfolio
738,000
Q3 2025 Added 321.71%
$6.51B
$10.1 Million 0.61% of portfolio
176,000
Q3 2025 New
$405M
$8.9 Million 0.54% of portfolio
1,450,000
Q3 2025 Reduced 31.57%
$3.94B
$8.21 Million 0.5% of portfolio
100,000
Q3 2025 Reduced 18.72%
$4.15B
$7.61 Million 0.46% of portfolio
88,000
Q3 2025 Reduced 29.6%
$55.3B
$6.95 Million 0.42% of portfolio
15,250
Q3 2025 Reduced 85.71%
$351M
$5.98 Million 0.36% of portfolio
619,874
Q3 2025 New
$1.55B
$5.72 Million 0.35% of portfolio
139,512
Q3 2025 Reduced 34.16%
$315M
$4.71 Million 0.29% of portfolio
2,162,162
Q2 2024 New
$428M
$4.37 Million 0.27% of portfolio
200,000
Q3 2025 Reduced 29.82%
$1.1B
$4.03 Million 0.25% of portfolio
85,498
Q3 2025 New
$17.6M
$3.54 Million 0.22% of portfolio
1,470,934
Q3 2025 Reduced 22.02%
$2.52B
$3.37 Million 0.2% of portfolio
71,000
Q3 2025 Reduced 1.39%
$1.54B
$2.72 Million 0.17% of portfolio
100,000
Q3 2025 Reduced 60.0%
$720M
$2.52 Million 0.15% of portfolio
300,000
Q3 2025 Reduced 58.9%
$383M
$2.37 Million 0.14% of portfolio
128,000
Q3 2025 Added 184.44%

Summary

  • Portfolio
  • No. of Stocks 88
  • Current Value $1.64 Billion
  • Prior Value $1.29 Billion
  • Filing
  • Period Q3 2025
  • Filing Date November 14, 2025
  • Form Type 13F-HR
  • Activity in Q3 2025
  • New Purchases 18 stocks
  • Additional Purchases 26 stocks
  • Sold out of 0 stocks
  • Reduced holdings in 34 stocks
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