Susquehanna Fundamental Investments, LLC Biotechnology

Susquehanna Fundamental Investments, LLC

$6.94 Billion
Q1 2025

Stock List

Stock	Market Cap.	Holding Value (Reported)	# of Shares.	Last Trade	Trade History
FULC Fulcrum Therapeutics, Inc.	$379M	$433,000 0.01% of portfolio	150,643	Q1 2025 Reduced 29.35%
QURE Uni Qure N.V.	$652M	$408,000 0.01% of portfolio	38,534	Q4 2024 New
KRYS Krystal Biotech, Inc.	$3.54B	$404,000 0.01% of portfolio	2,242	Q1 2025 New
ABUS Arbutus Biopharma Corp	$510M	$402,000 0.01% of portfolio	115,295	Q1 2025 Reduced 43.08%
ORIC Oric Pharmaceuticals, Inc.	$418M	$385,000 0.01% of portfolio	69,036	Q1 2025 Added 240.5%
SMMT Summit Therapeutics Inc.	$4.28B	$383,000 0.01% of portfolio	19,900	Q1 2025 Reduced 70.47%
HRMY Harmony Biosciences Holdings, Inc.	$1.89B	$381,000 0.01% of portfolio	11,497	Q4 2024 Reduced 25.34%
CMRX Chimerix Inc	$748M	$353,000 0.01% of portfolio	41,523	Q1 2025 Added 146.3%
TGTX Tg Therapeutics, Inc.	$5.31B	$352,000 0.01% of portfolio	8,950	Q1 2025 Reduced 7.25%
CCCC C4 Therapeutics, Inc.	$75.8M	$339,000 0.0% of portfolio	212,003	Q1 2025 Added 95.1%
TSVT 2seventy Bio, Inc.	$189M	$338,000 0.0% of portfolio	68,425	Q1 2025 Reduced 26.8%
TNGX Tango Therapeutics, Inc.	$482M	$318,000 0.0% of portfolio	232,766	Q1 2025 Reduced 32.97%
BPMC Blueprint Medicines Corp	$7.67B	$307,000 0.0% of portfolio	3,470	Q1 2025 Reduced 93.83%
EDIT Editas Medicine, Inc.	$144M	$282,000 0.0% of portfolio	243,497	Q1 2025 Reduced 10.62%
ZNTL Zentalis Pharmaceuticals, Inc.	$74.1M	$254,000 0.0% of portfolio	159,836	Q1 2025 New
VTYX Ventyx Biosciences, Inc.	$136M	$209,000 0.0% of portfolio	181,849	Q1 2025 Reduced 8.59%
ALEC Alector, Inc.	$114M	$169,000 0.0% of portfolio	137,904	Q1 2025 Reduced 4.92%
BDTX Black Diamond Therapeutics, Inc.	$90.1M	$169,000 0.0% of portfolio	109,277	Q1 2025 Added 45.89%
MGNX Macrogenics Inc	$83.6M	$141,000 0.0% of portfolio	111,280	Q1 2025 Added 24.85%
THRD Third Harmonic Bio, Inc.	$220M	$116,000 0.0% of portfolio	33,438	Q1 2025 New
OMER Omeros Corp	$205M	$113,000 0.0% of portfolio	13,764	Q1 2025 Reduced 90.86%
FATE Fate Therapeutics Inc	$111M	$93,000 0.0% of portfolio	118,186	Q4 2024 Reduced 54.96%
XERS Xeris Biopharma Holdings, Inc.	$628M	$93,000 0.0% of portfolio	17,087	Q1 2025 Reduced 13.32%
ANNX Annexon, Inc.	$117M	$79,000 0.0% of portfolio	41,011	Q1 2025 Reduced 65.75%
PHAT Phathom Pharmaceuticals, Inc.	$388M	$71,000 0.0% of portfolio	11,473	Q1 2025 New
ERAS Erasca, Inc.	$170M	$64,000 0.0% of portfolio	46,785	Q1 2025 Reduced 49.57%
ATXS Astria Therapeutics, Inc.	$88.9M	$59,000 0.0% of portfolio	11,051	Q1 2025 New
PROK Prokidney Corp Ord Shs Cl A(Cy	$40.6M	$39,000 0.0% of portfolio	44,707	Q1 2025 Reduced 14.24%
STRO Sutro Biopharma, Inc.	$42.3M	$24,000 0.0% of portfolio	37,956	Q1 2025 Reduced 56.77%
CRBU Caribou Biosciences, Inc.	$84M	$18,000 0.0% of portfolio	20,027	Q1 2025 Reduced 88.92%
SAVA Cassava Sciences Inc	$75.8M	$17,000 0.0% of portfolio	11,493	Q4 2024 New

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