Institutional shares held 101 Million
88.6K calls
32.5K puts
Total value of holdings $290M
$253K calls
$92K puts
Market Cap $136M
47,617,700 Shares Out.
Institutional ownership 212.65%
# of Institutions 152


Latest Institutional Activity in ANNX

Top Purchases

Q3 2025
Opaleye Management Inc. Shares Held: 2.6M ($7.44M)
Q3 2025
Morgan Stanley Shares Held: 3.03M ($8.67M)
Q3 2025
Woodline Partners LP Shares Held: 2.64M ($7.55M)
Q3 2025
Adage Capital Partners Gp, L.L.C. Shares Held: 1.5M ($4.29M)
Q3 2025
Balyasny Asset Management LLC Shares Held: 1.3M ($3.71M)

Top Sells

Q3 2025
Jpmorgan Chase & CO Shares Held: 46.9K ($134K)
Q3 2025
Tfg Asset Management Gp LTD Shares Held: 2.11M ($6.04M)
Q3 2025
Kennedy Capital Management, Inc. Shares Held: 640K ($1.83M)
Q3 2025
Bank Of America Corp Shares Held: 1.29M ($3.7M)
Q3 2025
J. Safra Sarasin Holding Ag Shares Held: 223K ($638K)

About ANNX

Annexon, Inc., a clinical-stage biopharmaceutical company, discovers and develops therapeutics for autoimmune, neurodegenerative, and ophthalmic disorders. The company's C1q is an initiating molecule of the classical complement pathway that targets distinct disease processes, such as antibody-mediated autoimmune disease and complement-mediated neurodegeneration. Its product candidates include ANX005, a monoclonal antibody, which is in Phase II/III clinical trials to treat patients with guillain- barré syndrome; Phase II trial in patients with warm autoimmune hemolytic anemia; and Phase II clinical trial for Huntington's disease and amyotrophic lateral sclerosis. The company is also developing ANX009 that is in Phase Ib trial in patients with lupus nephritis; and ANX007, which is in Phase II clinical trials to treat patients with geographic atrophy. In addition, it develops ANX105, an investigational monoclonal antibody targeting neurodegenerative indications; and ANX1502, an investigational oral small molecule for the treatment of certain autoimmune indications. The company was incorporated in 2011 and is headquartered in Brisbane, California.


Insider Transactions at ANNX

Insider Transaction List

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Date Insider Transaction Ownership Type Shares Traded Value / Price
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Last 12 Months Summary

Buy / Acquisition
2.42M Shares
From 4 Insiders
Open market or private purchase 2.38M shares
Exercise of conversion of derivative security 38K shares
Sell / Disposition
46K Shares
From 6 Insiders
Open market or private sale 46K shares

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