Two Sigma Investments, LP Alnylam Pharmaceuticals, Inc. Transaction History

Two Sigma Investments, LP

$50.6 Billion
Q2 2025

A detailed history of Two Sigma Investments, LP transactions in Alnylam Pharmaceuticals, Inc. stock. As of the latest transaction made, Two Sigma Investments, LP holds 343,305 shares of ALNY stock, worth $148 Million. This represents 0.22% of its overall portfolio holdings.

Number of Shares

343,305

Previous 197,415 73.9%

Holding current value

$148 Million

Previous $53.3 Million 110.01%

% of portfolio

0.22%

Previous 0.12%

21 transactions

Quarter	Operation	Price Per share	shares change	shares Held
Q2 2025 Aug 14, 2025	BUY	$224.32 - $326.09 $32.7 Million - $47.6 Million	145,890 Added 73.9%	343,305 $112 Million
Q1 2025 May 15, 2025	BUY	$233.07 - $290.7 $21 Million - $26.2 Million	90,298 Added 84.3%	197,415 $53.3 Million
Q4 2024 Feb 14, 2025	BUY	$232.27 - $300.43 $20.4 Million - $26.4 Million	87,969 Added 459.42%	107,117 $25.2 Million
Q3 2024 Nov 14, 2024	SELL	$233.81 - $287.01 $19.6 Million - $24 Million	-83,770 Reduced 81.39%	19,148 $5.27 Million
Q2 2024 Aug 14, 2024	BUY	$143.31 - $247.0 $58,183 - $100,282	406 Added 0.4%	102,918 $25 Million
Q1 2024 May 15, 2024	BUY	$146.51 - $198.2 $15 Million - $20.3 Million	102,512 New	102,512 $15.3 Million
Q3 2023 Nov 14, 2023	SELL	$170.77 - $211.65 $37.8 Million - $46.9 Million	-221,369 Reduced 98.53%	3,300 $584,000
Q2 2023 Aug 14, 2023	BUY	$185.01 - $212.05 $10.6 Million - $12.2 Million	57,323 Added 34.25%	224,669 $42.7 Million
Q1 2023 May 15, 2023	SELL	$182.66 - $235.53 $2.81 Million - $3.62 Million	-15,361 Reduced 8.41%	167,346 $33.5 Million
Q4 2022 Feb 14, 2023	SELL	$185.53 - $241.31 $6.31 Million - $8.21 Million	-34,005 Reduced 15.69%	182,707 $43.4 Million
Q3 2022 Nov 14, 2022	BUY	$138.54 - $232.0 $30 Million - $50.3 Million	216,712 New	216,712 $43.4 Million
Q2 2022 Aug 15, 2022	SELL	$120.42 - $169.29 $8.9 Million - $12.5 Million	-73,949 Closed	0 $0
Q1 2022 May 16, 2022	BUY	$127.18 - $173.91 $9.4 Million - $12.9 Million	73,949 New	73,949 $12.1 Million
Q2 2021 Aug 16, 2021	SELL	$128.63 - $176.89 $4.71 Million - $6.48 Million	-36,619 Closed	0 $0
Q1 2021 May 17, 2021	BUY	$126.83 - $175.69 $4.64 Million - $6.43 Million	36,619 New	36,619 $5.17 Million
Q4 2018 Feb 14, 2019	SELL	$62.67 - $88.33 $1.3 Million - $1.83 Million	-20,675 Closed	0 $0
Q3 2018 Nov 14, 2018	BUY	$87.52 - $122.67 $1.81 Million - $2.54 Million	20,675 New	20,675 $1.81 Million
Q2 2018 Aug 14, 2018	SELL	$88.31 - $107.8 $22.6 Million - $27.6 Million	-256,376 Closed	0 $0
Q1 2018 May 15, 2018	SELL	$115.92 - $148.54 $5.33 Million - $6.83 Million	-46,000 Reduced 15.21%	256,376 $30.5 Million
Q4 2017 Feb 14, 2018	BUY	$114.49 - $139.98 $18.1 Million - $22.2 Million	158,502 Added 110.17%	302,376 $38.4 Million
Q3 2017 Nov 14, 2017	BUY	$72.53 - $118.27 $10.4 Million - $17 Million	143,874	143,874 $16.9 Million

Others Institutions Holding ALNY

# of Institutions

742

Shares Held

115M

Call Options Held

584K

Put Options Held

672K

View Full List

About ALNYLAM PHARMACEUTICALS, INC.

Ticker ALNY
Exchange NASDAQ
Sector Healthcare
Industry Biotechnology
Shares Outstandng 123,028,000
Market Cap $52.9B
Description
Alnylam Pharmaceuticals, Inc., a biopharmaceutical company, focuses on discovering, developing, and commercializing novel therapeutics based on ribonucleic acid interference. The company's pipeline of investigational RNAi therapeutics focuses on genetic medicines, cardio-metabolic diseases, hepatic infectious diseases, and central nervous system...

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Two Sigma Investments, LP Alnylam Pharmaceuticals, Inc. Transaction History