Maria Luisa Maccecchini Annovis Bio, Inc. (ANVS) insider trading activity

Maria Luisa Maccecchini is President & CEO of Annovis Bio, Inc.. Currently has a direct ownership of 1.21 Million shares of ANVS, which is worth approximately $2.8 Million. The most recent transaction as insider was on Oct 28, 2025, when has been sold 97,561 shares (Common Stock) at a price of $2.05 per share, resulting in proceeds of $200,000. This information was disclosed in a Form 4 filing with the Securities and Exchange Commission (SEC).

Shares Held (Direct Ownership) 1.21M

8.75% 3M change

13.44% 12M change

Total Value Held $2.8 Million

Maria-Luisa Maccecchini Transaction History

Date	Transaction	Value	Shares Traded	Shares Held
Oct 28 2025	BUY Open market or private purchase	$200,000 $2.05 p/Share	97,561 Added 7.45%	1,212,020 Common Stock
Jun 04 2025	BUY Grant, award, or other acquisition	$155,020 $3.37 p/Share	46,000 Added 3.96%	1,114,459 Common Stock
Mar 31 2024	SELL Bona fide gift	-	20,000 Reduced 1.84%	1,068,459 Common Stock
Mar 28 2024	SELL Bona fide gift	-	10,000 Reduced 0.91%	1,088,459 Common Stock
Nov 20 2023	BUY Grant, award, or other acquisition	$249,999 $6.07 p/Share	41,186 Added 3.61%	1,098,675 Common Stock
Apr 24 2023	SELL Bona fide gift	-	3,000 Reduced 0.28%	1,057,489 Common Stock
Apr 07 2023	BUY Grant, award, or other acquisition	$252,200 $12.61 p/Share	20,000 Added 1.85%	1,060,489 Common Stock

Feb 06 2023	BUY Exercise of conversion of derivative security	$7,385 $0.14 p/Share	52,755 Added 4.83%	1,040,489 Common Stock
Jan 14 2022	BUY Exercise of conversion of derivative security	$4,614 $0.14 p/Share	32,959 Added 3.23%	987,734 Common Stock
Oct 11 2021	BUY Open market or private purchase	$496,980 $27.61 p/Share	18,000 Added 1.81%	976,775 Common Stock

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