Institutional shares held 97.6 Million
357K calls
301K puts
Total value of holdings $21.5M
$78K calls
$66K puts
Market Cap $10.6M
48,020,700 Shares Out.
Institutional ownership 203.28%
# of Institutions 79


Latest Institutional Activity in APLT

Top Purchases

Q3 2025
Pnc Financial Services Group, Inc. Shares Held: 2.9M ($638K)
Q3 2025
Vestal Point Capital, LP Shares Held: 14.3M ($3.14M)
Q3 2025
T. Rowe Price Investment Management, Inc. Shares Held: 21.4M ($4.71M)
Q3 2025
Ubs Group Ag Shares Held: 1.91M ($419K)
Q3 2025
Adage Capital Partners Gp, L.L.C. Shares Held: 2.21M ($487K)

Top Sells

Q3 2025
Qube Research & Technologies LTD Shares Held: 1.17M ($257K)
Q3 2025
Goldman Sachs Group Inc Shares Held: 155K ($34.1K)
Q3 2025
Two Sigma Investments, LP Shares Held: 199K ($43.8K)
Q3 2025
Aqr Capital Management LLC Shares Held: 110K ($24.1K)
Q3 2025
Susquehanna International Group, LLP Shares Held: 477K ($105K)

About APLT

Applied Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops novel products to target cardiovascular disease, galactosemia, and diabetic complications. Its lead product candidate is AT-007 that has completed phase 1/2 for the treatment of galactosemia in healthy volunteers and adults, as well as is in pediatric clinical study for the treatment of galactosemia in kids; for treating sorbitol dehydrogenase deficiency; and for the treatment of phosphomannomutase enzyme-CDG. The company also develops AT-001 that is in phase III clinical trials for treating diabetic cardiomyopathy, as well as for the treatment of diabetic peripheral neuropathy. Its preclinical stage products include AT-003 for the treatment diabetic retinopathy; AT-104, a PI3K inhibitor for treating orphan hematological oncology T Cell Acute Lymphoblastic Leukemia. Applied Therapeutics, Inc. was incorporated in 2016 and is headquartered in New York, New York.


Insider Transactions at APLT

Insider Transaction List

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Date Insider Transaction Ownership Type Shares Traded Value / Price
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Last 12 Months Summary

Buy / Acquisition
2.35M Shares
From 5 Insiders
Grant, award, or other acquisition 2.35M shares
Sell / Disposition
162K Shares
From 3 Insiders
Open market or private sale 162K shares

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