Institutional shares held 36.8 Million
752K calls
567K puts
Total value of holdings $5.14B
$105M calls
$79.1M puts
Market Cap $5.99B
42,878,000 Shares Out.
Institutional ownership 85.74%
# of Institutions 414


Latest Institutional Activity in AXSM

Top Purchases

Q3 2025
Wellington Management Group LLP Shares Held: 1.33M ($186M)
Q3 2025
Price T Rowe Associates Inc Shares Held: 1.04M ($145M)
Q3 2025
Invesco Ltd. Shares Held: 991K ($138M)
Q3 2025
Marshall Wace, LLP Shares Held: 378K ($52.8M)
Q3 2025
Sofinnova Investments, Inc. Shares Held: 393K ($55M)

Top Sells

Q3 2025
Bvf Inc Shares Held: 487K ($68M)
Q3 2025
Rtw Investments, LP Shares Held: 1.12M ($156M)
Q3 2025
Bank Of America Corp Shares Held: 361K ($50.5M)
Q3 2025
Ubs Group Ag Shares Held: 212K ($29.7M)
Q3 2025
Point72 Asset Management, L.P. Shares Held: 18.7K ($2.61M)

About AXSM

Axsome Therapeutics, Inc., a biopharmaceutical company, engages in the development of novel therapies for central nervous system (CNS) disorders in the United States. The company's product pipeline includes AXS-05, a therapeutic for the treatment of major depressive disorder and resistant depression disorders; and that is in the Phase III clinical trial to treat Alzheimer's disease agitation, as well as that has completed phase II clinical trial for the treatment of smoking cessation. It is also developing AXS-07, a novel, oral, rapidly absorbed, multi-mechanistic, and investigational medicine that has completed two Phase III trials for the acute treatment of migraine; AXS-12, a selective and potent norepinephrine reuptake inhibitor, which is in Phase III trial to treat narcolepsy; and AXS-14, a novel, oral, and investigational medicine that is in Phase III trial for the treatment of fibromyalgia. Axsome Therapeutics, Inc. has a research collaboration agreement with Duke University for evaluating AXS-05 in smoking cessation. The company was incorporated in 2012 and is based in New York, New York.


Insider Transactions at AXSM

Insider Transaction List

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Date Insider Transaction Ownership Type Shares Traded Value / Price
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Last 12 Months Summary

Buy / Acquisition
539K Shares
From 7 Insiders
Exercise of conversion of derivative security 537K shares
Open market or private purchase 1.58K shares
Sell / Disposition
654K Shares
From 7 Insiders
Open market or private sale 654K shares

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