Institutional shares held 129 Million
5.25M calls
1.18M puts
Total value of holdings $8.56B
$349M calls
$78.5M puts
Market Cap $6.25B
94,144,096 Shares Out.
Institutional ownership 136.92%
# of Institutions 450


Latest Institutional Activity in CYTK

Top Purchases

Q4 2025
Fifth Third Wealth Advisors LLC Shares Held: 3.21K ($213K)
Q4 2025
Ascent Group, LLC Shares Held: 3.15K ($209K)
Q4 2025
Retirement Systems Of Alabama Shares Held: 147K ($9.74M)
Q4 2025
Mirador Capital Partners LP Shares Held: 199K ($13.2M)
Q4 2025
Allspring Global Investments Holdings, LLC Shares Held: 6.34K ($421K)

Top Sells

Q4 2025
Abrdn PLC Shares Held: 483K ($32.1M)
Q4 2025
E. Ohman J:Or Asset Management Ab Shares Held: 363K ($24.1M)
Q4 2025
Sg Americas Securities, LLC Shares Held: 32.2K ($2.14M)
Q4 2025
Tema Etfs LLC Shares Held: 13.3K ($882K)
Q4 2025
Fny Investment Advisers, LLC Shares Held: 5.26K ($349K)

About CYTK

Cytokinetics, Incorporated, a late-stage biopharmaceutical company, focuses on discovering, developing, and commercializing muscle activators and inhibitors as potential treatments for debilitating diseases. The company develops small molecule drug candidates primarily engineered to impact muscle function and contractility. Its drug candidates include omecamtiv mecarbil, a novel cardiac myosin activator that is in Phase III clinical trial in patients with heart failure; and reldesemtiv, a skeletal muscle troponin activator, which is in Phase III clinical trial to treat amyotrophic lateral sclerosis and spinal muscular atrophy. The company also develops CK-136, a novel cardiac troponin activator that is in Phase I clinical trial; aficamten, a novel cardiac myosin inhibitor, which is in Phase III clinical trial for the treatment of patients with symptomatic obstructive hypertrophic cardiomyopathy; and CK-3772271, a small molecule cardiac myosin inhibitor that is in Phase I clinical trial. Cytokinetics, Incorporated has a strategic alliance with Astellas Pharma Inc. The company was incorporated in 1997 and is headquartered in South San Francisco, California.


Insider Transactions at CYTK

Insider Transaction List

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Date Insider Transaction Ownership Type Shares Traded Value / Price
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Last 12 Months Summary

Buy / Acquisition
708K Shares
From 22 Insiders
Grant, award, or other acquisition 395K shares
Exercise of conversion of derivative security 313K shares
Sell / Disposition
556K Shares
From 16 Insiders
Open market or private sale 502K shares
Payment of exercise price or tax liability 51.7K shares
Bona fide gift 2.2K shares

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