Institutional shares held 61.3 Million
1.01M calls
555K puts
Total value of holdings $3.06B
$50.2M calls
$27.7M puts
Market Cap $2.45B
49,084,100 Shares Out.
Institutional ownership 124.85%
# of Institutions 301


Latest Institutional Activity in PTGX

Top Purchases

Q2 2025
Assenagon Asset Management S.A. Shares Held: 91.9K ($4.58M)
Q2 2025
Exchange Traded Concepts, LLC Shares Held: 47.4K ($2.36M)
Q2 2025
Nbc Securities, Inc. Shares Held: 2.57K ($128K)
Q2 2025
Massmutual Trust CO Fsb Shares Held: 119 ($5.93K)
Q2 2025
Parallel Advisors, LLC Shares Held: 97 ($4.84K)

Top Sells

Q2 2025
Farther Finance Advisors, LLC Shares Held: 93 ($4.64K)
Q2 2025
Gamma Investing LLC Shares Held: 1.08K ($53.7K)
Q2 2025
Fifth Third Bancorp Shares Held: 211 ($10.5K)
Q1 2025
Jefferies Financial Group Inc. Shares Held: 632K ($31.5M)
Q1 2025
State Street Corp Shares Held: 2.71M ($135M)

About PTGX

Protagonist Therapeutics, Inc., a biopharmaceutical company, discovers and develops peptide-based therapeutic drugs to address hematology and blood disorders, and inflammatory and immunomodulatory diseases. It is developing rusfertide (PTG-300), an injectable hepcidin mimetic that is in Phase II clinical trials for the treatment of patients with polycythemia vera and hereditary hemochromatosis, as well as for the treatment of other blood disorders; PN-943, an oral, alpha-4-beta-7 integrin- specific antagonist peptide that is in Phase II clinical trials for treating inflammatory bowel disease (IBD); and PN-235, an orally delivered interleukin-23 receptor specific antagonist for the treatment of IBD and non-IBD indications. The company has a license and collaboration agreement with Janssen Biotech, Inc. Protagonist Therapeutics, Inc. was incorporated in 2006 and is headquartered in Newark, California.


Insider Transactions at PTGX

Insider Transaction List

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Date Insider Transaction Ownership Type Shares Traded Value / Price
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Last 12 Months Summary

Buy / Acquisition
625K Shares
From 14 Insiders
Grant, award, or other acquisition 248K shares
Exercise of conversion of derivative security 377K shares
Sell / Disposition
402K Shares
From 7 Insiders
Payment of exercise price or tax liability 12.6K shares
Bona fide gift 9.36K shares
Open market or private sale 380K shares

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