Institutional Ownership Spero Therapeutics, Inc. (SPRO)
This table provides information about the institutional ownership of Spero Therapeutics, Inc. (SPRO). We have compiled data on the 51 institutions that hold shares in the stock, with a total of 10.6 Million shares, which have been reported (via 13F filing form) to have a value of $25.6 Million.
| Holding | Report Date | shares Held | Holding Value (Reported) | Last Trade | Trade History |
|---|---|---|---|---|---|
|
Vanguard Group Inc
Valley Forge, PA |
Nov 07, 2025 Q3 2025 |
1,989,855
shares
|
$4.8 Million
0.0% of portfolio
|
Q3 2025
Added 2.02%
|
|
|
Anson Funds Management LP
Dallas, TX |
Nov 13, 2025 Q3 2025 |
1,603,569
shares
|
$3.86 Million
0.5% of portfolio
|
Q3 2025
Reduced 0.74%
|
|
|
Jim Simons
Renaissance Technologies LLC | New York, Ny
|
Nov 13, 2025 Q3 2025 |
1,452,765
shares
|
$3.5 Million
0.0% of portfolio
|
Q3 2025
Added 74.58%
|
|
|
Atlas Venture Associates Ix, LLC
Boston, MA |
Nov 13, 2023 Q3 2023 |
1,353,303
shares
|
$3.26 Million
14.54% of portfolio
|
Q2 2023
Reduced 1.72%
|
|
|
Alphabet Inc.
Mountain View, CA |
Nov 06, 2025 Q3 2025 |
889,979
shares
|
$2.14 Million
0.1% of portfolio
|
Q4 2020
Reduced 20.0%
|
|
|
Geode Capital Management, LLC
Boston, MA |
Nov 12, 2025 Q3 2025 |
527,477
shares
|
$1.27 Million
0.0% of portfolio
|
Q3 2025
Added 3.29%
|
|
|
Black Rock Inc.
New York, NY |
Aug 13, 2024 Q2 2024 |
483,402
shares
|
$1.16 Million
0.0% of portfolio
|
Q2 2024
Added 1.36%
|
|
|
Eam Investors, LLC
Solana Beach, CA |
Nov 14, 2025 Q3 2025 |
282,445
shares
|
$680,692
0.07% of portfolio
|
Q3 2025
Added 18.11%
|
|
|
Oup Management Co., LLC
|
Nov 09, 2023 Q3 2023 |
249,070
shares
|
$600,258
0.68% of portfolio
|
Q4 2021
New holding
|
|
|
Ionic Capital Management LLC
New York, NY |
Nov 14, 2025 Q3 2025 |
208,725
shares
|
$503,027
0.04% of portfolio
|
Q3 2025
Added 39.15%
|
|
|
State Street Corp
Boston, MA |
Nov 14, 2025 Q3 2025 |
190,951
shares
|
$460,191
0.0% of portfolio
|
Q3 2025
Added 24.44%
|
|
|
Arrowstreet Capital, Limited Partnership
Boston, MA |
Nov 13, 2025 Q3 2025 |
150,516
shares
|
$362,743
0.0% of portfolio
|
Q3 2025
New holding
|
|
|
Northern Trust Corp
Chicago, IL |
Nov 14, 2025 Q3 2025 |
129,643
shares
|
$312,439
0.0% of portfolio
|
Q3 2025
Added 28.57%
|
|
|
Adar1 Capital Management, LLC
Austin, TX |
Nov 14, 2025 Q3 2025 |
115,539
shares
|
$278,448
0.02% of portfolio
|
Q3 2025
Reduced 19.72%
|
|
|
Bridgeway Capital Management, LLC
Houston, TX |
Nov 14, 2025 Q3 2025 |
114,800
shares
|
$276,668
0.0% of portfolio
|
Q2 2025
Reduced 25.84%
|
|
|
Intrepid Family Office LLC
Greenwich, CT |
Nov 14, 2025 Q3 2025 |
110,000
shares
|
$265,100
0.18% of portfolio
|
Q3 2025
New holding
|
|
|
Gsa Capital Partners LLP
London, X0 |
Nov 07, 2025 Q3 2025 |
106,894
shares
|
$257,614
0.02% of portfolio
|
Q3 2025
New holding
|
|
|
Shay Capital LLC
New York, NY |
Nov 14, 2025 Q3 2025 |
63,667
shares
|
$153,437
0.01% of portfolio
|
Q3 2025
New holding
|
|
|
Two Sigma Investments, LP
New York, NY |
Nov 14, 2025 Q3 2025 |
49,399
shares
|
$119,051
0.0% of portfolio
|
Q3 2025
New holding
|
|
|
Morgan Stanley
New York, NY |
Nov 14, 2025 Q3 2025 |
43,378
shares
|
$104,540
0.0% of portfolio
|
Q3 2025
Added 370.43%
|
|
|
Jane Street Group, LLC
New York, NY |
Nov 13, 2025 Q3 2025 |
42,988
shares
|
$103,601
0.0% of portfolio
|
Q3 2025
New holding
|
|
|
Cubist Systematic Strategies, LLC
Stamford, CT |
Nov 14, 2025 Q3 2025 |
40,845
shares
|
$98,436
0.0% of portfolio
|
Q3 2025
Added 50.5%
|
|
|
American Century Companies Inc
Kansas City, MO |
Nov 12, 2025 Q3 2025 |
40,219
shares
|
$96,927
0.0% of portfolio
|
Q3 2025
New holding
|
|
|
Assenagon Asset Management S.A.
|
Oct 07, 2025 Q3 2025 |
36,993
shares
|
$89,153
0.0% of portfolio
|
Q3 2025
New holding
|
|
|
Xtx Topco LTD
London, X0 |
Nov 14, 2025 Q3 2025 |
33,801
shares
|
$81,460
0.0% of portfolio
|
Q3 2025
Reduced 2.17%
|
|