Institutional shares held 244 Million
107K calls
17K puts
Total value of holdings $709M
$311K calls
$49K puts
Market Cap $141M
48,359,500 Shares Out.
Institutional ownership 503.53%
# of Institutions 154


Latest Institutional Activity in TSHA

Top Purchases

Q2 2025
Ra Capital Management, L.P. Shares Held: 23.6M ($68.5M)
Q2 2025
Goldman Sachs Group Inc Shares Held: 12.6M ($36.6M)
Q2 2025
Jefferies Financial Group Inc. Shares Held: 10.3M ($30M)
Q2 2025
Rtw Investments, LP Shares Held: 25M ($72.8M)
Q2 2025
Deerfield Management Company, L.P. (Series C) Shares Held: 5.39M ($15.7M)

Top Sells

Q2 2025
Granahan Investment Management, LLC Shares Held: 958K ($2.79M)
Q2 2025
Barclays PLC Shares Held: 451K ($1.31M)
Q2 2025
Palo Alto Investors LP Shares Held: 1.25M ($3.63M)
Q2 2025
Ubs Group Ag Shares Held: 261K ($760K)
Q2 2025
Northern Trust Corp Shares Held: 1.33M ($3.87M)

About TSHA

Taysha Gene Therapies, Inc., a gene therapy company, focuses on developing and commercializing adeno-associated virus-based gene therapies for the treatment of monogenic diseases of the central nervous system. It primarily develops TSHA-120 for the treatment of giant axonal neuropathy; TSHA-102 for the treatment of Rett syndrome; TSHA-121 for the treatment of CLN1 disease; TSHA-118 for the treatment of CLN1 disease; TSHA-105 foe the treatment of for SLC13A5 Deficiency; and TSHA-101 for the treatment of GM2 gangliosidosis. Taysha Gene Therapies, Inc. has a strategic partnership with The University of Texas Southwestern Medical Center to develop and commercialize transformative gene therapy treatments. The company was incorporated in 2019 and is based in Dallas, Texas.


Insider Transactions at TSHA

Insider Transaction List

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Date Insider Transaction Ownership Type Shares Traded Value / Price
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Last 12 Months Summary

Buy / Acquisition
2.62M Shares
From 8 Insiders
Open market or private purchase 750K shares
Grant, award, or other acquisition 1.87M shares
Sell / Disposition
29.8K Shares
From 1 Insiders
Payment of exercise price or tax liability 29.8K shares

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