Institutional shares held 247 Million
463K calls
246K puts
Total value of holdings $1.04B
$1.95M calls
$1.03M puts
Market Cap $204M
48,359,500 Shares Out.
Institutional ownership 511.68%
# of Institutions 160


Latest Institutional Activity in TSHA

Top Purchases

Q3 2025
Barclays PLC Shares Held: 5.15M ($21.7M)
Q3 2025
Affinity Asset Advisors, LLC Shares Held: 3M ($12.6M)
Q3 2025
Vestal Point Capital, LP Shares Held: 5.5M ($23.2M)
Q3 2025
Morgan Stanley Shares Held: 19.3M ($81.3M)
Q3 2025
D. E. Shaw & Co., Inc. Shares Held: 2.71M ($11.4M)

Top Sells

Q3 2025
Jefferies Financial Group Inc. Shares Held: 2.16M ($9.08M)
Q3 2025
Octagon Capital Advisors LP Shares Held: 9.07M ($38.2M)
Q3 2025
Toronto Dominion Bank Shares Held: 1.92M ($8.1M)
Q3 2025
Adage Capital Partners Gp, L.L.C. Shares Held: 3.33M ($14M)
Q3 2025
Jpmorgan Chase & CO Shares Held: 296K ($1.25M)

About TSHA

Taysha Gene Therapies, Inc., a gene therapy company, focuses on developing and commercializing adeno-associated virus-based gene therapies for the treatment of monogenic diseases of the central nervous system. It primarily develops TSHA-120 for the treatment of giant axonal neuropathy; TSHA-102 for the treatment of Rett syndrome; TSHA-121 for the treatment of CLN1 disease; TSHA-118 for the treatment of CLN1 disease; TSHA-105 foe the treatment of for SLC13A5 Deficiency; and TSHA-101 for the treatment of GM2 gangliosidosis. Taysha Gene Therapies, Inc. has a strategic partnership with The University of Texas Southwestern Medical Center to develop and commercialize transformative gene therapy treatments. The company was incorporated in 2019 and is based in Dallas, Texas.


Insider Transactions at TSHA

Insider Transaction List

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Date Insider Transaction Ownership Type Shares Traded Value / Price
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Last 12 Months Summary

Buy / Acquisition
2.67M Shares
From 9 Insiders
Open market or private purchase 750K shares
Grant, award, or other acquisition 1.87M shares
Exercise of conversion of derivative security 41.2K shares
Sell / Disposition
341K Shares
From 3 Insiders
Payment of exercise price or tax liability 29.8K shares
Open market or private sale 312K shares

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