Siren, L.L.C. Portfolio Holdings

Siren, L.L.C.

  • $2.56 Trillion
  • Q3 2025

Siren, L.L.C. has filed its 13F form on November 13, 2025 for Q3 2025 where it was disclosed a total value porftolio of $2.56 Trillion distributed in 117 stocks.

Among their holdings, we can observe that their the top five positions include companies like: Scholar Rock Holding Corp with a value of $344B, Kymera Therapeutics, Inc. with a value of $194B, Bei Gene, Ltd. with a value of $168B, Arrowhead Pharmaceuticals, Inc. with a value of $92.1B, and Bicara Therapeutics Inc with a value of $82.4B.

Examining the 13F form we can see an increase of $624B in the current position value, from $1.93T to 2.56T.

Siren, L.L.C. is based out at New York, NY

Below you can find more details about Siren, L.L.C. portfolio as well as his latest detailed transactions.

Portfolio value $2.56 Trillion
Technology: $123 Billion
Communication Services: $57.5 Billion
Consumer Cyclical: $21.1 Billion
Consumer Defensive: $5.26 Billion
Real Estate: $2.76 Billion
Financial Services: $938 Million
Industrials: $302 Million
Healthcare: $145 Million
Other: $0

Stock Holdings Table Market Cap. of $300 Millions to $2 Billions

Stock Market Cap. Holding Value (Reported) # of Shares. Last Trade Trade History
$1.95B
$344 Billion 13.48% of portfolio
9,250,005
Q4 2024 Reduced 17.85%
$1.44B
$63.2 Billion 2.47% of portfolio
3,897,099
Q3 2025 Added 23.31%
$975M
$59.8 Billion 2.34% of portfolio
4,729,174
Q3 2025 Reduced 2.22%
$1.05B
$52.8 Billion 2.07% of portfolio
2,247,347
Q1 2025 Added 12.37%
$720M
$49.4 Billion 1.93% of portfolio
5,883,188
Q3 2025 Added 74.84%
$385M
$45.8 Billion 1.79% of portfolio
4,870,000
Q3 2025 New
$1.45B
$39.6 Billion 1.55% of portfolio
2,912,077
Q3 2025 Added 80.64%
$965M
$34 Billion 1.33% of portfolio
9,969,495
Q3 2024 New
$600M
$27.1 Billion 1.06% of portfolio
3,696,322
Q1 2025 Reduced 1.44%
$661M
$23.2 Billion 0.91% of portfolio
2,536,867
Q3 2025 Reduced 35.59%
$315M
$19.1 Billion 0.75% of portfolio
8,757,249
Q1 2025 Reduced 1.13%
$1.4B
$16.1 Billion 0.63% of portfolio
275,200
Q3 2025 New
$518M
$12.1 Billion 0.47% of portfolio
1,007,575
Q3 2024 New
$390M
$7.08 Billion 0.28% of portfolio
1,193,410
Q1 2025 Reduced 1.48%
$347M
$4.41 Billion 0.17% of portfolio
1,165,957
Q3 2025 New
$875M
$1.86 Billion 0.07% of portfolio
47,500
Q3 2025 New

Summary

  • Portfolio
  • No. of Stocks 117
  • Current Value $2.56 Trillion
  • Prior Value $1.93 Trillion
  • Filing
  • Period Q3 2025
  • Filing Date November 13, 2025
  • Form Type 13F-HR
  • Activity in Q3 2025
  • New Purchases 24 stocks
  • Additional Purchases 24 stocks
  • Sold out of 0 stocks
  • Reduced holdings in 14 stocks
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