Sr One Capital Management, LP Portfolio Holdings

Sr One Capital Management, LP

  • $279 Million
  • Q2 2025

Sr One Capital Management, LP has filed its 13F form on August 14, 2025 for Q2 2025 where it was disclosed a total value porftolio of $279 Million distributed in 13 stocks.

Among their holdings, we can observe that their the top five positions include companies like: Arcellx, Inc. with a value of $155M, Crispr Therapeutics Ag with a value of $51M, Oric Pharmaceuticals, Inc. with a value of $45.8M, Design Therapeutics, Inc. with a value of $22M, and Nkarta, Inc. with a value of $5.53M.

Examining the 13F form we can see an increase of $57.9M in the current position value, from $221M to 279M.

Below you can find more details about Sr One Capital Management, LP portfolio as well as his latest detailed transactions.

Portfolio value $279 Million
Healthcare: $279 Million

Stock Holdings Table

Stock Market Cap. Holding Value (Reported) # of Shares. Last Trade Trade History
$3.19B
$155 Million 55.41% of portfolio
2,346,630
Q1 2024 Reduced 25.42%
$4.42B
$51 Million 18.29% of portfolio
1,048,951
Q1 2024 New
$377M
$45.8 Million 16.43% of portfolio
4,514,929
Q2 2025 New
$278M
$22 Million 7.89% of portfolio
6,526,476
Q4 2022 Added 16.0%
$95.4M
$5.53 Million 1.98% of portfolio
3,333,333
Q1 2024 Added 150.0%
Alumis Inc.
-
$0 0.0% of portfolio
-
Q2 2024 New
Oruka Therapeutics, Inc
-
$0 0.0% of portfolio
-
Q4 2024 Added 14.65%
Oculis Holding Ag
-
$0 0.0% of portfolio
-
Q1 2025 New
Mineralys Therapeutics Inc.
-
$0 0.0% of portfolio
-
Q1 2025 Added 55.09%
Kala Bio, Inc.
-
$0 0.0% of portfolio
-
Q4 2024 Added 35.0%
En Gene Holdings Inc.
-
$0 0.0% of portfolio
-
Q3 2024 Added 49.55%
$0
$0 0.0% of portfolio
4,012,903
Q1 2023 Added 33.33%
Zenas Bio Pharma, Inc
-
$0 0.0% of portfolio
-
Q3 2024 New

Summary

  • Portfolio
  • No. of Stocks 13
  • Current Value $279 Million
  • Prior Value $221 Million
  • Filing
  • Period Q2 2025
  • Filing Date August 14, 2025
  • Form Type 13F-HR
  • Activity in Q2 2025
  • New Purchases 1 stocks
  • Additional Purchases 0 stocks
  • Sold out of 0 stocks
  • Reduced holdings in 0 stocks
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