Institutional shares held 61.8 Million
297K calls
235K puts
Total value of holdings $2.42B
$11.6M calls
$9.21M puts
Market Cap $2.15B
54,818,000 Shares Out.
Institutional ownership 112.7%
# of Institutions 235


Latest Institutional Activity in AGIO

Top Purchases

Q2 2025
Paradigm Biocapital Advisors LP Shares Held: 1.14M ($44.8M)
Q2 2025
Tcg Crossover Management, LLC Shares Held: 697K ($27.4M)
Q2 2025
Rock Springs Capital Management LP Shares Held: 990K ($38.8M)
Q2 2025
Wellington Management Group LLP Shares Held: 422K ($16.6M)
Q2 2025
Millennium Management LLC Shares Held: 300K ($11.8M)

Top Sells

Q2 2025
Armistice Capital, LLC Shares Held: 1.17M ($45.8M)
Q2 2025
State Street Corp Shares Held: 1.95M ($76.6M)
Q2 2025
Arrow Mark Colorado Holdings LLC Shares Held: 659K ($25.9M)
Q2 2025
Dimensional Fund Advisors LP Shares Held: 1.11M ($43.4M)
Q2 2025
Casdin Capital, LLC Shares Held: 100K ($3.93M)

About AGIO

Agios Pharmaceuticals, Inc., a biopharmaceutical company, engages in the discovery and development of medicines in the field of cellular metabolism and adjacent areas of biology. The company offers PYRUKYND (mitapivat) an activator of both wild-type and a variety of mutant pyruvate kinase, PK, enzymes for the treatment of hemolytic anemias; and AG-946 that is in Phase I clinical study for treating hemolytic anemias and other indications. Agios Pharmaceuticals, Inc. was incorporated in 2007 and is headquartered in Cambridge, Massachusetts.


Insider Transactions at AGIO

Insider Transaction List

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Date Insider Transaction Ownership Type Shares Traded Value / Price
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Last 12 Months Summary

Buy / Acquisition
264K Shares
From 14 Insiders
Exercise of conversion of derivative security 264K shares
Sell / Disposition
142K Shares
From 9 Insiders
Open market or private sale 142K shares

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