Institutional shares held 62 Million
158K calls
199K puts
Total value of holdings $0
$0 calls
$0 puts
Market Cap N/A
Institutional ownership 140.91%
# of Institutions 186


Latest Institutional Activity in ALPN

Top Purchases

Q1 2024
Avoro Capital Advisors LLC Shares Held: 5.78M ($0)
Q1 2024
Darwin Global Management, Ltd. Shares Held: 1.98M ($0)
Q1 2024
State Street Corp Shares Held: 2.85M ($0)
Q1 2024
Price T Rowe Associates Inc Shares Held: 3.08M ($0)
Q1 2024
Decheng Capital LLC Shares Held: 8.32M ($0)

Top Sells

Q1 2024
Great Point Partners LLC Shares Held: 1.13M ($0)
Q1 2024
Lynx1 Capital Management LP Shares Held: 2.25M ($0)
Q1 2024
Paradigm Biocapital Advisors LP Shares Held: 2.12M ($0)
Q1 2024
Woodline Partners LP Shares Held: 254K ($0)
Q1 2024
Citadel Advisors LLC Shares Held: 143K ($0)

About ALPN

Alpine Immune Sciences, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery and development of protein-based immunotherapies for the treatment of cancer, autoimmune/inflammatory disorders, and other diseases. Its product pipeline includes ALPN-101, an inducible T cell costimulator (ICOS)/cluster of differentiation 28 (CD28) antagonist program for the treatment of autoimmune and inflammatory diseases; ALPN-202, a conditional CD28 costimulator and dual checkpoint inhibitor for the treatment of cancer; and ALPN-303, a dual B cell cytokine antagonist for the treatment of B cell-mediated inflammatory and autoimmune diseases. The company has a collaboration agreement with AbbVie Ireland Unlimited Company for the development of ALPN-101; and Adaptimmune Therapeutics plc to develop next-generation SPEAR T cell products. Alpine Immune Sciences, Inc. was incorporated in 2007 and is headquartered in Seattle, Washington.


Insider Transactions at ALPN

Insider Transaction List

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Date Insider Transaction Ownership Type Shares Traded Value / Price
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Last 12 Months Summary

Buy / Acquisition
5.94M Shares
From 16 Insiders
Exercise of in-the-money or at-the-money derivatives securities 4.11M shares
Open market or private purchase 750K shares
Grant, award, or other acquisition 206K shares
Exercise of conversion of derivative security 883K shares
Sell / Disposition
23.5M Shares
From 18 Insiders
Open market or private sale 3.59M shares
Disposition due to a tender of shares in a change of control transaction 19.1M shares
Sale (or disposition) back to the issuer 727K shares
Payment of exercise price or tax liability 48.3K shares

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