James M Frates Amylyx Pharmaceuticals, Inc. (AMLX) insider trading activity

James M Frates is Chief Financial Officer of Amylyx Pharmaceuticals, Inc.. Currently has a direct ownership of 177,104 shares of AMLX, which is worth approximately $2.25 Million. The most recent transaction as insider was on Jan 06, 2026, when has been sold 3,326 shares (Common Stock) at a price of $11.11 per share, resulting in proceeds of $36,951. This information was disclosed in a Form 4 filing with the Securities and Exchange Commission (SEC).

Shares Held (Direct Ownership) 177K

36.85% 3M change

24.14% 12M change

Total Value Held $2.25 Million

JAMES M FRATES Transaction History

Date	Transaction	Value	Shares Traded	Shares Held
Jan 06 2026	SELL Open market or private sale	$36,951 $11.11 p/Share	3,326 Reduced 1.84%	177,104 Common Stock
Sep 30 2025	SELL Open market or private sale	$154,674 $14.65 p/Share	10,558 Reduced 3.63%	280,430 Common Stock
Mar 31 2025	SELL Open market or private sale	$37,809 $3.47 p/Share	10,896 Reduced 3.61%	290,988 Common Stock
Mar 06 2025	BUY Grant, award, or other acquisition	-	68,420 Added 18.48%	301,884 Common Stock
Sep 12 2024	BUY Open market or private purchase	$101,199 $2.53 p/Share	40,000 Added 14.63%	233,464 Common Stock
Apr 16 2024	BUY Grant, award, or other acquisition	-	91,180 Added 28.75%	225,964 Common Stock
Mar 05 2024	SELL Open market or private sale	$33,564 $18.73 p/Share	1,792 Reduced 1.31%	134,784 Common Stock

Feb 26 2024	BUY Grant, award, or other acquisition	-	40,000 Added 20.83%	152,035 Common Stock
Jan 09 2024	SELL Open market or private sale	$44,352 $16.33 p/Share	2,716 Reduced 2.37%	112,035 Common Stock
Aug 23 2023	BUY Exercise of conversion of derivative security	$124,975 $6.88 p/Share	18,165 Added 14.59%	106,341 Common Stock
May 16 2023	SELL Open market or private sale	$886,275 $27.27 p/Share	32,500 Reduced 36.86%	55,676 Common Stock
May 16 2023	BUY Exercise of conversion of derivative security	$223,600 $6.88 p/Share	32,500 Added 26.93%	88,176 Common Stock
Mar 16 2023	SELL Open market or private sale	$1,045,199 $32.16 p/Share	32,500 Reduced 95.56%	1,509 Common Stock
Mar 16 2023	BUY Grant, award, or other acquisition	-	21,667 Added 48.32%	23,176 Common Stock
Jan 06 2023	BUY Open market or private sale	$96,857 $36.44 p/Share	2,658 Added 7.25%	34,009 Common Stock
Dec 30 2022	BUY Exercise of conversion of derivative security	$34,400 $6.88 p/Share	5,000 Added 12.0%	36,667 Common Stock
Jan 06 2022	BUY Grant, award, or other acquisition	-	31,667 Added 50.0%	31,667 Common Stock

Also insider at

SAGE

Sage Therapeutics, Inc. Healthcare

JMF

James M Frates

Chief Financial Officer

Cambridge, MA

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