Institutional shares held 32 Million
1.16M calls
804K puts
Total value of holdings $257M
$9.33M calls
$6.46M puts
Market Cap $626M
77,942,800 Shares Out.
Institutional ownership 41.08%
# of Institutions 198


Latest Institutional Activity in AVXL

Top Purchases

Q3 2025
Sheets Smith Investment Management Shares Held: 136K ($1.09M)
Q3 2025
October Effect LTD Shares Held: 245K ($1.97M)
Q3 2025
Gladstone Institutional Advisory LLC Shares Held: 59.5K ($478K)
Q3 2025
Janney Montgomery Scott LLC Shares Held: 16.2K ($130K)
Q3 2025
Sg Americas Securities, LLC Shares Held: 10.9K ($87.8K)

Top Sells

Q3 2025
Nwam LLC Shares Held: 874K ($7.02M)
Q3 2025
Voya Investment Management LLC Shares Held: 15.6K ($126K)
Q3 2025
Commonwealth Equity Services, LLC Shares Held: 107K ($861K)
Q3 2025
Wealth Enhancement Advisory Services, LLC Shares Held: 11.5K ($92.2K)
Q3 2025
Geneos Wealth Management Inc. Shares Held: 42.4K ($340K)

About AVXL

Anavex Life Sciences Corp., a clinical stage biopharmaceutical company, engages in the development of drug candidates for the treatment of central nervous system (CNS) diseases. Its lead drug candidate is ANAVEX 2-73, which is in Phase III clinical trial for the treatment of Alzheimer's disease; Phase III clinical trial to treat pediatric patients with Rett syndrome; Phase II clinical trial for the treatment of Parkinson's disease; and preclinical clinical trials to treat epilepsy, infantile spasms, Fragile X syndrome, Angelman syndrome, multiple sclerosis, and tuberous sclerosis complex. The company's drug candidate also comprises ANAVEX 3-71, which is in Phase I clinical trial for the treatment of frontotemporal dementia and other dementia indications; and preclinical clinical trials for the treatment of neurodegenerative diseases, such as Alzheimer's and Parkinson's diseases. Its preclinical drug candidates include ANAVEX 1-41, a sigma-1 receptor agonist for the treatment of depression, stroke, Parkinson's, and Alzheimer's diseases; ANAVEX 1066, a mixed sigma-1/sigma-2 ligand for the potential treatment of neuropathic and visceral pain; and ANAVEX 1037 to treat prostate and pancreatic cancer. The company was incorporated in 2004 and is headquartered in New York, New York.


Insider Transactions at AVXL

Insider Transaction List

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Date Insider Transaction Ownership Type Shares Traded Value / Price
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Last 12 Months Summary

Buy / Acquisition
738K Shares
From 2 Insiders
Exercise of conversion of derivative security 738K shares
Sell / Disposition
439K Shares
From 2 Insiders
Payment of exercise price or tax liability 439K shares

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