Institutional shares held 121 Million
1.49M calls
258K puts
Total value of holdings $465M
$5.75M calls
$996K puts
Market Cap $255M
65,950,200 Shares Out.
Institutional ownership 182.76%
# of Institutions 109


Latest Institutional Activity in CTMX

Top Purchases

Q3 2025
Ikarian Capital, LLC Shares Held: 3.37M ($13M)
Q3 2025
Perceptive Advisors LLC Shares Held: 9.68M ($37.4M)
Q3 2025
Citadel Advisors LLC Shares Held: 1.8M ($6.95M)
Q3 2025
Vr Adviser, LLC Shares Held: 15.6M ($60.1M)
Q3 2025
Kynam Capital Management, LP Shares Held: 3.65M ($14.1M)

Top Sells

Q3 2025
Point72 Asset Management, L.P. Shares Held: 4.07M ($15.7M)
Q3 2025
Prosight Management, LP Shares Held: 565K ($2.18M)
Q3 2025
Vivo Capital, LLC Shares Held: 2.88M ($11.1M)
Q3 2025
Marshall Wace, LLP Shares Held: 1.1M ($4.27M)
Q3 2025
Acadian Asset Management LLC Shares Held: 654K ($2.52M)

About CTMX

CytomX Therapeutics, Inc. operates as an oncology-focused biopharmaceutical company in the United States. The company develops antibody therapeutics based on its Probody technology platform for the treatment of cancer. The company's product candidates include CX-2009, an antibody drug conjugates (ADC) against CD166, which is in Phase II clinical trials for the treatment of breast cancer; CX-2029 that is in Phase II clinical trials for the treatment of squamous non-small cell lung cancer, head and neck squamous cell carcinoma, esophageal and gastro-esophageal junction cancers, and diffuse large B-cell lymphoma; BMS-986249, a CTLA-4 Probody therapeutic drug, which is in Phase I/II clinical trials for the treatment of metastatic melanoma; and BMS-986288, an anti-CTLA-4 Probody drug, which is in Phase I clinical trials for the treatment of solid tumors. It also develops CX-2043, a conditionally activated ADC targeting the epithelial cell adhesion molecule, as well as CX-904, a conditionally activated epidermal growth factor receptor for the treatment of solid tumor. The company has strategic collaborations with AbbVie Ireland Unlimited Company, Amgen, Inc., Bristol-Myers Squibb Company, ImmunoGen, Inc., Pfizer Inc., and Astellas Pharma Inc. to develop Probody therapeutics. CytomX Therapeutics, Inc. was founded in 2008 and is headquartered in South San Francisco, California.


Insider Transactions at CTMX

Insider Transaction List

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Date Insider Transaction Ownership Type Shares Traded Value / Price
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Last 12 Months Summary

Buy / Acquisition
903K Shares
From 7 Insiders
Grant, award, or other acquisition 678K shares
Exercise of conversion of derivative security 225K shares
Sell / Disposition
263K Shares
From 5 Insiders
Open market or private sale 263K shares

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