C Frank Bennett Ionis Pharmaceuticals Inc (IONS) insider trading activity

C Frank Bennett is EVP, Chief Scientific Officer of IONIS PHARMACEUTICALS INC. Currently has a direct ownership of 82,679 shares of IONS, which is worth approximately $5.79 Million. The most recent transaction as insider was on Sep 05, 2025, when has been sold 6,000 shares (Common Stock) at a price of $59.6 per share, resulting in proceeds of $357,600. This information was disclosed in a Form 4 filing with the Securities and Exchange Commission (SEC).

Shares Held (Direct Ownership) 82.7K

11.54% 3M change

3.86% 12M change

Total Value Held $5.79 Million

C FRANK BENNETT Transaction History

Date	Transaction	Value	Shares Traded	Shares Held
Sep 05 2025	SELL Open market or private sale	$357,600 $59.6 p/Share	6,000 Reduced 6.77%	82,679 Common Stock
Sep 03 2025	SELL Exercise of conversion of derivative security	$792,796 $61.5 p/Share	12,891 Reduced 12.69%	88,679 Common Stock
Sep 03 2025	SELL Open market or private sale	$2,055,563 $60.62 p/Share	33,909 Reduced 25.03%	101,570 Common Stock
Sep 03 2025	BUY Exercise of conversion of derivative security	$2,516,436 $53.77 p/Share	46,800 Added 25.67%	135,479 Common Stock
Sep 02 2025	SELL Open market or private sale	$245,700 $49.14 p/Share	5,000 Reduced 5.34%	88,679 Common Stock
Aug 29 2025	BUY Other acquisition or disposition	$5,902 $27.71 p/Share	213 Added 0.23%	93,679 Common Stock
Aug 18 2025	SELL Open market or private sale	$439,799 $43.98 p/Share	10,000 Reduced 9.67%	93,466 Common Stock
Aug 18 2025	BUY Exercise of conversion of derivative security	$326,000 $32.6 p/Share	10,000 Added 8.81%	103,466 Common Stock
Feb 28 2025	BUY Other acquisition or disposition	$9,027 $28.21 p/Share	320 Added 0.34%	93,466 Common Stock
Jan 31 2025	SELL Open market or private sale	$43,074 $32.46 p/Share	1,327 Reduced 1.4%	93,146 Common Stock
Jan 30 2025	BUY Grant, award, or other acquisition	-	3,607 Added 3.68%	94,473 Common Stock
Jan 16 2025	SELL Open market or private sale	$222,140 $32.9 p/Share	6,752 Reduced 6.92%	90,866 Common Stock
Jan 15 2025	BUY Exercise of conversion of derivative security	-	18,011 Added 15.58%	97,618 Common Stock
Aug 30 2024	BUY Other acquisition or disposition	$6,839 $38.64 p/Share	177 Added 0.22%	79,607 Common Stock
Feb 29 2024	BUY Other acquisition or disposition	$13,182 $34.42 p/Share	383 Added 0.48%	79,462 Common Stock
Feb 02 2024	SELL Open market or private sale	$91,760 $49.52 p/Share	1,853 Reduced 2.29%	79,079 Common Stock
Feb 01 2024	BUY Grant, award, or other acquisition	-	3,609 Added 4.27%	80,932 Common Stock
Jan 17 2024	SELL Open market or private sale	$340,082 $50.42 p/Share	6,745 Reduced 8.02%	77,323 Common Stock
Jan 16 2024	BUY Exercise of conversion of derivative security	-	18,314 Added 17.89%	84,068 Common Stock
Dec 21 2023	SELL Open market or private sale	$794,209 $49.29 p/Share	16,113 Reduced 19.68%	65,754 Common Stock
Dec 21 2023	BUY Exercise of conversion of derivative security	$762,789 $47.34 p/Share	16,113 Added 16.45%	81,867 Common Stock
Dec 20 2023	SELL Open market or private sale	$322,660 $49.64 p/Share	6,500 Reduced 9.0%	65,754 Common Stock
Dec 20 2023	BUY Exercise of conversion of derivative security	$307,710 $47.34 p/Share	6,500 Added 8.25%	72,254 Common Stock
Dec 14 2023	SELL Open market or private sale	$1,123,816 $49.7 p/Share	22,612 Reduced 25.59%	65,754 Common Stock
Dec 14 2023	BUY Exercise of conversion of derivative security	$1,070,452 $47.34 p/Share	22,612 Added 23.32%	74,364 Common Stock

CFB

C Frank Bennett

EVP, Chief Scientific Officer

Carlsbad, CA

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