Institutional shares held 37.7 Million
733K calls
611K puts
Total value of holdings $380M
$7.4M calls
$6.17M puts
Market Cap $359M
35,575,300 Shares Out.
Institutional ownership 105.88%
# of Institutions 144


Latest Institutional Activity in ITOS

Top Purchases

Q2 2025
Eco R1 Capital, LLC Shares Held: 10.7M ($108M)
Q2 2025
Tang Capital Management LLC Shares Held: 3.83M ($38.6M)
Q2 2025
Orbimed Advisors LLC Shares Held: 700K ($7.07M)
Q2 2025
Nantahala Capital Management, LLC Shares Held: 597K ($6.03M)
Q2 2025
Dld Asset Management, LP Shares Held: 577K ($5.82M)

Top Sells

Q2 2025
Citadel Advisors LLC Shares Held: 94.3K ($952K)
Q2 2025
Goldman Sachs Group Inc Shares Held: 155K ($1.57M)
Q2 2025
Acadian Asset Management LLC Shares Held: 187K ($1.89M)
Q2 2025
Dimensional Fund Advisors LP Shares Held: 833K ($8.41M)
Q2 2025
Nuveen, LLC Shares Held: 154K ($1.56M)

About ITOS

Iteos Therapeutics, Inc., a clinical-stage biopharmaceutical company, engages in the discovery and development of immuno-oncology therapeutics for patients. The company's product pipeline includes inupadenant, a small molecule antagonist of the adenosine A2AR antagonists that is in Phase 2 clinical trials; and EOS-448, an antagonist of TIGIT or T-cell immunoreceptor with Ig and ITIM domains, which is in Phase 1/2 clinical trial, as well as used to engage the Fc gamma receptor, or Fc?R to activate dendritic cells and macrophages and to promote antibody-dependent cellular cytotoxicity, or ADCC activity. Iteos Therapeutics, Inc. was founded in 2011 and is headquartered in Watertown, Massachusetts.


Insider Transactions at ITOS

Insider Transaction List

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Date Insider Transaction Ownership Type Shares Traded Value / Price
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Last 12 Months Summary

Buy / Acquisition
5.66M Shares
From 10 Insiders
Open market or private purchase 4.96M shares
Exercise of conversion of derivative security 510K shares
Grant, award, or other acquisition 187K shares
Sell / Disposition
2.67M Shares
From 5 Insiders
Open market or private sale 2.67M shares

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