Institutional shares held 73.2 Million
336K calls
309K puts
Total value of holdings $3.12B
$14.4M calls
$13.2M puts
Market Cap $2.66B
62,263,500 Shares Out.
Institutional ownership 117.54%
# of Institutions 222


Latest Institutional Activity in XENE

Top Purchases

Q3 2025
Jennison Associates LLC Shares Held: 1.14M ($48.4M)
Q3 2025
Campbell & CO Investment Adviser LLC Shares Held: 28.7K ($1.22M)
Q3 2025
Sanders Morris Harris LLC Shares Held: 21.5K ($917K)
Q3 2025
Altfest L J & CO Inc Shares Held: 7.73K ($330K)
Q3 2025
Citizens Financial Group Inc Shares Held: 5K ($213K)

Top Sells

Q3 2025
Harbor Capital Advisors, Inc. Shares Held: 11.2K ($479K)
Q3 2025
Sg Americas Securities, LLC Shares Held: 6.93K ($296K)
Q3 2025
Teacher Retirement System Of Texas Shares Held: 16K ($683K)
Q3 2025
Mutual Of America Capital Management LLC Shares Held: 94.9K ($4.05M)
Q3 2025
Signaturefd, LLC Shares Held: 416 ($17.8K)

About XENE

Xenon Pharmaceuticals Inc., a clinical-stage biopharmaceutical company, engages in developing therapeutics to treat patients with neurological disorders in Canada. Its clinical development pipeline includes XEN496, A Kv7 potassium channel opener that is Phase III clinical trials for the treatment of KCNQ2 developmental and epilepsy encephalopathy; and XEN1101, A Kv7 potassium channel opener, which is in Phase II clinical trial for the treatment of epilepsy and other neurological disorders. The company's product candidates also comprise NBI-921352, a selective Nav1.6 sodium channel inhibitor that is in Phase II clinical trials for the treatment of SCN8A developmental and epileptic encephalopathy, and other potential indications, including adult focal epilepsy; and XEN007, A central nervous system-acting calcium channel modulator, which is in Phase II clinical trials. It has a license and collaboration agreement with the Neurocrine Biosciences, Inc. to develop treatments for epilepsy; and with Flexion Therapeutics, Inc. to develop PCRX301 (XEN402, a Nav1.7 inhibitor) for the treatment of post-operative pain. Xenon Pharmaceuticals Inc. was incorporated in 1996 and is headquartered in Burnaby, Canada.


Insider Transactions at XENE

Insider Transaction List

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Date Insider Transaction Ownership Type Shares Traded Value / Price
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Last 12 Months Summary

Buy / Acquisition
117K Shares
From 4 Insiders
Exercise of conversion of derivative security 117K shares
Sell / Disposition
112K Shares
From 6 Insiders
Open market or private sale 104K shares
Payment of exercise price or tax liability 8.32K shares

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