Institutional shares held 73.2 Million
336K calls
309K puts
Total value of holdings $2.87B
$13.2M calls
$12.1M puts
Market Cap $2.45B
62,263,500 Shares Out.
Institutional ownership 117.49%
# of Institutions 221


Latest Institutional Activity in XENE

Top Purchases

Q2 2025
Holocene Advisors, LP Shares Held: 1.81M ($71.1M)
Q2 2025
State Street Corp Shares Held: 1.38M ($54.3M)
Q2 2025
Geode Capital Management, LLC Shares Held: 970K ($38.1M)
Q2 2025
Braidwell LP Shares Held: 3.61M ($142M)
Q2 2025
Commodore Capital LP Shares Held: 3.03M ($119M)

Top Sells

Q2 2025
Wellington Management Group LLP Shares Held: 2.17M ($85.5M)
Q2 2025
Capital World Investors Shares Held: 656K ($25.8M)
Q2 2025
T. Rowe Price Investment Management, Inc. Shares Held: 76.9K ($3.02M)
Q2 2025
Adage Capital Partners Gp, L.L.C. Shares Held: 1.29M ($50.7M)
Q2 2025
Citadel Advisors LLC Shares Held: 120K ($4.72M)

About XENE

Xenon Pharmaceuticals Inc., a clinical-stage biopharmaceutical company, engages in developing therapeutics to treat patients with neurological disorders in Canada. Its clinical development pipeline includes XEN496, A Kv7 potassium channel opener that is Phase III clinical trials for the treatment of KCNQ2 developmental and epilepsy encephalopathy; and XEN1101, A Kv7 potassium channel opener, which is in Phase II clinical trial for the treatment of epilepsy and other neurological disorders. The company's product candidates also comprise NBI-921352, a selective Nav1.6 sodium channel inhibitor that is in Phase II clinical trials for the treatment of SCN8A developmental and epileptic encephalopathy, and other potential indications, including adult focal epilepsy; and XEN007, A central nervous system-acting calcium channel modulator, which is in Phase II clinical trials. It has a license and collaboration agreement with the Neurocrine Biosciences, Inc. to develop treatments for epilepsy; and with Flexion Therapeutics, Inc. to develop PCRX301 (XEN402, a Nav1.7 inhibitor) for the treatment of post-operative pain. Xenon Pharmaceuticals Inc. was incorporated in 1996 and is headquartered in Burnaby, Canada.


Insider Transactions at XENE

Insider Transaction List

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Date Insider Transaction Ownership Type Shares Traded Value / Price
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Last 12 Months Summary

Buy / Acquisition
92.1K Shares
From 4 Insiders
Exercise of conversion of derivative security 92.1K shares
Sell / Disposition
86.9K Shares
From 6 Insiders
Open market or private sale 78.6K shares
Payment of exercise price or tax liability 8.32K shares

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