Dafna Capital Management LLC Portfolio Holdings

Dafna Capital Management LLC

  • $344 Million
  • Q2 2025

Dafna Capital Management LLC has filed its 13F form on August 14, 2025 for Q2 2025 where it was disclosed a total value porftolio of $344 Million distributed in 76 stocks.

Among their holdings, we can observe that their the top five positions include companies like: Spdr Ser Tr Spdr S&P Biotech E with a value of $34.5M, Stereotaxis, Inc. with a value of $29M, Revolution Medicines, Inc. with a value of $24.9M, Blueprint Medicines Corp with a value of $21.6M, and Merus N.V. with a value of $21M.

Examining the 13F form we can see an increase of $12.6M in the current position value, from $331M to 344M.

Dafna Capital Management LLC is based out at Los Angeles, CA

Below you can find more details about Dafna Capital Management LLC portfolio as well as his latest detailed transactions.

Portfolio value $344 Million
Healthcare: $296 Million
ETFs: $47.4 Million

Stock Holdings Table Companies Only

Stock Market Cap. Holding Value (Reported) # of Shares. Last Trade Trade History
$199M
$29 Million 8.43% of portfolio
13,680,554
Q1 2018 Added 896.5%
$3.09B
$24.9 Million 7.24% of portfolio
677,176
Q2 2025 Added 3.2%
$7.73B
$21.6 Million 6.29% of portfolio
168,763
Q2 2025 Added 10.84%
$2.93B
$21 Million 6.1% of portfolio
398,804
Q2 2025 Reduced 13.64%
$1.66B
$19.4 Million 5.64% of portfolio
592,273
Q1 2025 Reduced 7.7%
$3.23B
$13.2 Million 3.82% of portfolio
398,100
Q1 2024 Reduced 0.48%
$1.13B
$13 Million 3.78% of portfolio
619,090
Q2 2025 Added 5.05%
$10.9B
$12.5 Million 3.65% of portfolio
72,677
Q2 2025 Reduced 9.6%
$2.24B
$9.01 Million 2.62% of portfolio
287,939
Q2 2025 Added 5.19%
$12.3B
$8.88 Million 2.58% of portfolio
70,615
Q2 2025 Reduced 1.4%
$599M
$8.05 Million 2.34% of portfolio
741,782
Q2 2025 Added 8.96%
$363M
$6.93 Million 2.01% of portfolio
811,046
Q2 2025 Added 14.06%
$301M
$6.58 Million 1.91% of portfolio
581,757
Q2 2025 Reduced 22.68%
$31B
$5.72 Million 1.66% of portfolio
65,552
Q1 2024 Reduced 2.96%
$451M
$5.71 Million 1.66% of portfolio
879,163
Q2 2025 Added 20.21%
$533M
$5.7 Million 1.66% of portfolio
501,972
Q2 2025 Added 13.06%
$3.55B
$5.27 Million 1.53% of portfolio
191,493
Q2 2025 Added 12.65%
$698M
$5.11 Million 1.49% of portfolio
627,626
Q2 2025 Added 0.4%
$734M
$5.09 Million 1.48% of portfolio
543,602
Q2 2025 Reduced 0.17%
$437M
$4.79 Million 1.39% of portfolio
349,515
Q2 2025 Reduced 29.03%
$173M
$4.26 Million 1.24% of portfolio
605,625
Q2 2025 Added 32.21%
$2.09B
$3.64 Million 1.06% of portfolio
130,175
Q4 2023 Added 116.33%
$136M
$3.2 Million 0.93% of portfolio
1,567,561
Q4 2024 Added 73.1%
$846M
$3.12 Million 0.91% of portfolio
238,140
Q2 2025 Added 30.03%
$21.5B
$3.11 Million 0.9% of portfolio
9,900
Q2 2025 Reduced 16.81%
$4.49B
$2.97 Million 0.86% of portfolio
103,748
Q2 2025 Added 10.14%
$30.7M
$2.8 Million 0.81% of portfolio
1,441,029
Q4 2024 New
$415M
$2.67 Million 0.78% of portfolio
463,368
Q1 2025 Added 3.35%
$1.77B
$2.36 Million 0.69% of portfolio
168,500
Q2 2025 Added 31.74%
$11B
$2.08 Million 0.61% of portfolio
11,000
Q1 2025 Added 100.0%
$1.55B
$1.96 Million 0.57% of portfolio
218,255
Q2 2025 Reduced 60.9%
$353M
$1.74 Million 0.51% of portfolio
130,316
Q4 2024 Added 76.69%
$101M
$1.74 Million 0.51% of portfolio
324,775
Q2 2025 Added 3.18%
$3.06B
$1.71 Million 0.5% of portfolio
64,516
Q4 2024 Reduced 48.64%
$138M
$1.67 Million 0.49% of portfolio
1,222,358
Q4 2022 Added 29.79%
$201M
$1.67 Million 0.49% of portfolio
127,151
Q2 2025 Reduced 18.77%
$148M
$1.56 Million 0.45% of portfolio
1,380,118
Q1 2025 Added 11.29%
$203M
$1.41 Million 0.41% of portfolio
300,452
Q2 2025 Reduced 1.41%
$359M
$1.4 Million 0.41% of portfolio
140,847
Q2 2025 Reduced 33.98%
$321M
$1.37 Million 0.4% of portfolio
526,660
Q2 2025 New
$377M
$1.37 Million 0.4% of portfolio
135,271
Q2 2025 Reduced 44.1%
$489M
$1.32 Million 0.38% of portfolio
245,000
Q4 2024 Added 68.97%
$165M
$1.28 Million 0.37% of portfolio
912,928
Q1 2024 Added 49.68%
$92.3M
$1.17 Million 0.34% of portfolio
471,000
Q2 2025 Added 236.43%
$160M
$1.07 Million 0.31% of portfolio
371,434
Q4 2024 Reduced 24.85%
$181M
$1.05 Million 0.3% of portfolio
849,921
Q2 2025 Reduced 6.38%
$30.6M
$954,000 0.28% of portfolio
1,704,232
Q2 2024 Added 30.35%
$195M
$970,000 0.28% of portfolio
425,616
Q2 2025 Reduced 27.45%
$26.9B
$745,000 0.22% of portfolio
7,000
Q2 2025 Reduced 33.33%

Summary

  • Portfolio
  • No. of Stocks 76
  • Current Value $344 Million
  • Prior Value $331 Million
  • Filing
  • Period Q2 2025
  • Filing Date August 14, 2025
  • Form Type 13F-HR
  • Activity in Q2 2025
  • New Purchases 3 stocks
  • Additional Purchases 22 stocks
  • Sold out of 0 stocks
  • Reduced holdings in 21 stocks
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