Institutional shares held 57.6 Million
258K calls
81.2K puts
Total value of holdings $44.4M
$198K calls
$62K puts
Market Cap $61.5M
79,806,600 Shares Out.
Institutional ownership 72.18%
# of Institutions 98


Latest Institutional Activity in KPTI

Top Purchases

Q3 2024
Gsa Capital Partners LLP Shares Held: 1.78M ($1.37M)
Q3 2024
Eversept Partners, LP Shares Held: 5.55M ($4.27M)
Q3 2024
Renaissance Technologies LLC Shares Held: 1.24M ($956K)
Q3 2024
D. E. Shaw & Co., Inc. Shares Held: 1.05M ($806K)
Q3 2024
Acadian Asset Management LLC Shares Held: 369K ($284K)

Top Sells

Q3 2024
Jane Street Group, LLC Shares Held: 205K ($158K)
Q3 2024
Goldman Sachs Group Inc Shares Held: 1.34M ($1.03M)
Q3 2024
Millennium Management LLC Shares Held: 1.26M ($967K)
Q3 2024
Barclays PLC Shares Held: 95.8K ($73.7K)
Q3 2024
Aqr Capital Management LLC Shares Held: 12.2K ($9.41K)

About KPTI

Karyopharm Therapeutics Inc., a commercial-stage pharmaceutical company, discovers, develops, and commercializes drugs directed against nuclear export for the treatment of cancer and other diseases. The company discovers, develops, and commercializes novel and Selective Inhibitor of Nuclear Export (SINE) compounds function by binding with and inhibiting the nuclear export protein XPO1. Its lead compound, include XPOVIO in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma, in combination with dexamethasone for the treatment of adult patients with heavily pretreated multiple myeloma, and for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma. The company has license agreement with Menarini Group to develop and commercialize NEXPOVIO for human oncology indications in Europe, including the United Kingdom; Latin America; and other countries. Its oral SINE compounds also designed to force nuclear accumulation in the levels of multiple tumor suppressor and growth regulatory proteins. The company was incorporated in 2008 and is headquartered in Newton, Massachusetts.


Insider Transactions at KPTI

Insider Transaction List

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Date Insider Transaction Ownership Type Shares Traded Value / Price
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Last 12 Months Summary

Buy / Acquisition
1.47M Shares
From 6 Insiders
Grant, award, or other acquisition 1.47M shares
Sell / Disposition
2.03M Shares
From 7 Insiders
Open market or private sale 2.03M shares

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