Exome Asset Management LLC Portfolio Holdings

Exome Asset Management LLC

  • $165 Billion
  • Q3 2025

Exome Asset Management LLC has filed its 13F form on November 14, 2025 for Q3 2025 where it was disclosed a total value porftolio of $165 Billion distributed in 68 stocks.

Among their holdings, we can observe that their the top five positions include companies like: Ionis Pharmaceuticals Inc with a value of $8.57B, Cytokinetics Inc with a value of $7.83B, Bridge Bio Pharma, Inc. with a value of $6.91B, Cogent Biosciences, Inc. with a value of $6.37B, and Guardant Health, Inc. with a value of $6.13B.

Examining the 13F form we can see an increase of $30.6B in the current position value, from $135B to 165B.

Exome Asset Management LLC is based out at New York, NY

Below you can find more details about Exome Asset Management LLC portfolio as well as his latest detailed transactions.

Portfolio value $165 Billion
Healthcare: $123 Billion
ETFs: $2.71 Billion

Stock Holdings Table

Stock Market Cap. Holding Value (Reported) # of Shares. Last Trade Trade History
$10.2B
$8.57 Billion 5.19% of portfolio
131,016
Q3 2025 Added 8.17%
$6.25B
$7.83 Billion 4.74% of portfolio
142,417
Q3 2025 Added 22.97%
$9.84B
$6.91 Billion 4.19% of portfolio
133,087
Q3 2025 Reduced 14.43%
$2.21B
$6.37 Billion 3.86% of portfolio
443,547
Q3 2025 Reduced 16.88%
$9.65B
$6.13 Billion 3.71% of portfolio
98,182
Q2 2025 Reduced 22.8%
$971B
$5.99 Billion 3.63% of portfolio
7,852
Q3 2025 Added 68.03%
$347M
$5.44 Billion 3.3% of portfolio
1,439,604
Q3 2025 New
Praxis Precision Medicines I
-
$5.41 Billion 3.27% of portfolio
-
Q3 2025 Added 72.87%
$766M
$4.54 Billion 2.75% of portfolio
156,072
Q3 2025 Added 103.48%
$277B
$4.27 Billion 2.59% of portfolio
28,362
Q3 2025 New
Disc Medicine Inc
-
$4.05 Billion 2.46% of portfolio
-
Q2 2025 Reduced 0.49%
$690M
$4.02 Billion 2.44% of portfolio
273,661
Q3 2025 Added 17.24%
$2.21B
$3.75 Billion 2.27% of portfolio
156,917
Q3 2025 Added 2.37%
Apogee Therapeutics Inc
-
$3.75 Billion 2.27% of portfolio
-
Q3 2025 New
$20.8B
$3.68 Billion 2.23% of portfolio
18,100
Q3 2025 Reduced 32.96%
$4.37B
$3.6 Billion 2.18% of portfolio
104,507
Q3 2025 New
Soleno Therapeutics Inc
-
$3.27 Billion 1.98% of portfolio
-
Q3 2025 Added 16.34%
$19.8B
$3 Billion 1.82% of portfolio
18,650
Q1 2025 Reduced 16.93%
Corbus Pharmaceuticals Hldgs
-
$2.91 Billion 1.76% of portfolio
-
Q3 2025 Reduced 17.08%
$193B
$2.84 Billion 1.72% of portfolio
6,358
Q1 2025 Reduced 14.39%
$1.44B
$2.81 Billion 1.7% of portfolio
173,439
Q3 2025 Added 39.34%
$21.2B
$2.79 Billion 1.69% of portfolio
6,645
Q3 2025 New
$2.52B
$2.78 Billion 1.68% of portfolio
58,579
Q3 2025 New
$3.55B
$2.56 Billion 1.55% of portfolio
158,622
Q3 2025 New
$423M
$2.55 Billion 1.54% of portfolio
1,858,354
Q3 2025 Reduced 45.57%
$255M
$2.38 Billion 1.44% of portfolio
745,305
Q3 2025 New
$10.6B
$2.28 Billion 1.38% of portfolio
9,000
Q4 2024 New
$4.29B
$2.21 Billion 1.34% of portfolio
27,143
Q3 2025 New
$1.84B
$2.14 Billion 1.3% of portfolio
94,235
Q3 2025 Added 359.68%
$2.6B
$2.13 Billion 1.29% of portfolio
88,024
Q3 2025 Reduced 47.27%
$1.51B
$1.91 Billion 1.16% of portfolio
163,658
Q2 2025 New
$38.4B
$1.88 Billion 1.14% of portfolio
6,000
Q3 2025 New
$940M
$1.81 Billion 1.1% of portfolio
117,783
Q3 2025 Reduced 61.8%
Waystar Hldg Corp
-
$1.78 Billion 1.08% of portfolio
-
Q2 2025 New
Sarepta Therapeutics Inc
-
$1.76 Billion 1.07% of portfolio
-
Q2 2025 New
Karyopharm Therapeutics Inc
-
$1.63 Billion 0.99% of portfolio
-
Q1 2025 New
$14.8B
$1.63 Billion 0.98% of portfolio
7,955
Q3 2025 Reduced 21.24%
$518M
$1.45 Billion 0.88% of portfolio
120,644
Q3 2025 New
$1.32B
$1.42 Billion 0.86% of portfolio
39,900
Q3 2025 New
$2.49B
$1.38 Billion 0.84% of portfolio
18,600
Q3 2025 New
$1.4B
$1.29 Billion 0.78% of portfolio
22,090
Q3 2025 New
$472M
$1.28 Billion 0.77% of portfolio
178,084
Q3 2025 New
Avalo Therapeutics Inc
-
$1.27 Billion 0.77% of portfolio
-
Q3 2025 New
$255M
$1.19 Billion 0.72% of portfolio
451,699
Q3 2025 Reduced 58.86%
Alumis Inc
-
$1.17 Billion 0.71% of portfolio
-
Q3 2025 New
Upstream Bio Inc
-
$977 Million 0.59% of portfolio
-
Q3 2025 New
Mbx Biosciences Inc
-
$917 Million 0.56% of portfolio
-
Q3 2025 Reduced 16.92%
$451M
$909 Million 0.55% of portfolio
98,799
Q3 2025 Reduced 77.8%
$1.55B
$537 Million 0.33% of portfolio
13,100
Q4 2024 Reduced 39.63%

Summary

  • Portfolio
  • No. of Stocks 68
  • Current Value $165 Billion
  • Prior Value $135 Billion
  • Filing
  • Period Q3 2025
  • Filing Date November 14, 2025
  • Form Type 13F-HR
  • Activity in Q3 2025
  • New Purchases 21 stocks
  • Additional Purchases 10 stocks
  • Sold out of 0 stocks
  • Reduced holdings in 12 stocks
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