Orbimed Advisors LLC Portfolio Holdings

Orbimed Advisors LLC

  • $2.93 Billion
  • Q3 2025

Orbimed Advisors LLC has filed its 13F form on November 14, 2025 for Q3 2025 where it was disclosed a total value porftolio of $2.93 Billion distributed in 110 stocks.

Among their holdings, we can observe that their the top five positions include companies like: Edgewise Therapeutics, Inc. with a value of $252M, Boston Scientific Corp with a value of $237M, Eli Lilly & CO with a value of $230M, Alnylam Pharmaceuticals, Inc. with a value of $138M, and Stryker Corp with a value of $133M.

Examining the 13F form we can see an increase of $129M in the current position value, from $2.8B to 2.93B.

Orbimed Advisors LLC is based out at San Diego, CA

Below you can find more details about Orbimed Advisors LLC portfolio as well as his latest detailed transactions.

Portfolio value $2.93 Billion
Healthcare: $2.93 Billion

Stock Holdings Table

Stock Market Cap. Holding Value (Reported) # of Shares. Last Trade Trade History
$1.44B
$252 Million 8.59% of portfolio
15,518,492
Q2 2025 Added 3.31%
$147B
$237 Million 8.1% of portfolio
2,429,300
Q3 2025 Reduced 13.65%
$971B
$230 Million 7.84% of portfolio
301,200
Q3 2025 Reduced 10.78%
$55.3B
$138 Million 4.69% of portfolio
301,600
Q3 2025 Reduced 11.79%
$136B
$133 Million 4.53% of portfolio
359,200
Q1 2025 Added 4.3%
$53.4B
$131 Million 4.47% of portfolio
1,684,000
Q3 2025 Reduced 1.41%
$193B
$128 Million 4.38% of portfolio
287,200
Q3 2025 Reduced 1.31%
$50.2B
$127 Million 4.34% of portfolio
172,300
Q3 2025 Reduced 17.16%
$3.69B
$71.4 Million 2.44% of portfolio
1,638,886
Q3 2025 Reduced 9.6%
$19.8B
$69.1 Million 2.36% of portfolio
429,300
Q3 2025 Reduced 27.66%
$5.99B
$64.6 Million 2.2% of portfolio
531,800
Q3 2025 Added 24.28%
$846M
$57.5 Million 1.96% of portfolio
7,562,971
Q3 2024 Reduced 0.74%
$494M
$57.1 Million 1.95% of portfolio
15,219,994
Q2 2025 Reduced 31.94%
$11.9B
$54.4 Million 1.86% of portfolio
994,616
Q3 2025 Added 63.77%
$2.23B
$52.6 Million 1.79% of portfolio
2,323,368
Q3 2025 Added 56.74%
$160B
$52.2 Million 1.78% of portfolio
263,100
Q3 2025 New
$13.9B
$49.6 Million 1.69% of portfolio
353,640
Q3 2025 Reduced 19.36%
$21.2B
$48.2 Million 1.64% of portfolio
114,900
Q3 2025 New
$82.8B
$46.9 Million 1.6% of portfolio
162,800
Q3 2025 New
$2.34B
$45.8 Million 1.56% of portfolio
1,099,000
Q3 2025 Reduced 4.35%
$518M
$43.4 Million 1.48% of portfolio
3,641,756
Q3 2025 Added 304.96%
$1.22B
$43.2 Million 1.47% of portfolio
1,766,100
Q3 2025 Added 45.92%
$14.3B
$41.1 Million 1.4% of portfolio
2,714,798
Q3 2025 Reduced 2.33%
$11.4B
$38.2 Million 1.3% of portfolio
191,905
Q3 2025 Added 457.86%
$598M
$38 Million 1.3% of portfolio
2,578,979
Q2 2025 Reduced 25.09%
$155M
$34.3 Million 1.17% of portfolio
6,059,528
Q3 2024 Added 8.99%
$2.3B
$30 Million 1.02% of portfolio
290,000
Q3 2025 Reduced 33.09%
$661M
$29.6 Million 1.01% of portfolio
3,308,400
Q2 2025 Added 195.39%
$975M
$29.3 Million 1.0% of portfolio
2,314,184
Q3 2025 Added 124.37%
$319M
$27.3 Million 0.93% of portfolio
2,614,184
Q2 2025 Reduced 23.26%
$255M
$27 Million 0.92% of portfolio
8,461,500
Q2 2025 New
$1.4B
$26.8 Million 0.91% of portfolio
458,500
Q3 2025 New
$2.52B
$25 Million 0.85% of portfolio
526,200
Q3 2025 Added 149.03%
$404M
$24.9 Million 0.85% of portfolio
1,796,000
Q3 2025 New
$307M
$23.6 Million 0.81% of portfolio
5,907,351
Q2 2025 Reduced 1.02%
$222B
$22.6 Million 0.77% of portfolio
46,500
Q2 2025 Reduced 63.95%
$5.54B
$21.7 Million 0.74% of portfolio
215,152
Q3 2025 Reduced 13.42%
$5.29B
$18.1 Million 0.62% of portfolio
102,745
Q3 2025 Added 1,016.79%
$2.54B
$16.8 Million 0.57% of portfolio
419,600
Q3 2025 Reduced 55.73%
$445M
$16.1 Million 0.55% of portfolio
1,018,734
Q3 2024 Reduced 19.7%
$83.1M
$14.7 Million 0.5% of portfolio
6,306,127
Q3 2025 New
$55.6M
$14.6 Million 0.5% of portfolio
10,909,256
Q2 2023 Added 8.66%
$747M
$13.6 Million 0.46% of portfolio
2,380,715
Q2 2025 Added 5.89%
$553M
$13.4 Million 0.46% of portfolio
689,000
Q3 2025 Added 44.02%
$2.66B
$13 Million 0.44% of portfolio
1,645,400
Q3 2025 Reduced 28.0%
$1.92B
$11.8 Million 0.4% of portfolio
197,900
Q2 2025 Reduced 69.73%
$121M
$11.6 Million 0.4% of portfolio
5,235,146
Q3 2025 Reduced 23.35%
$390M
$11.4 Million 0.39% of portfolio
1,923,855
Q1 2025 Reduced 0.96%
$743M
$10.2 Million 0.35% of portfolio
750,600
Q3 2025 Added 139.66%

Summary

  • Portfolio
  • No. of Stocks 110
  • Current Value $2.93 Billion
  • Prior Value $2.8 Billion
  • Filing
  • Period Q3 2025
  • Filing Date November 14, 2025
  • Form Type 13F-HR
  • Activity in Q3 2025
  • New Purchases 19 stocks
  • Additional Purchases 13 stocks
  • Sold out of 0 stocks
  • Reduced holdings in 23 stocks
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