David A. Siegel Biotechnology

Two Sigma Advisers, LP

  • $47 Billion
  • Q3 2025

Stock List

Stock Market Cap. Holding Value (Reported) # of Shares. Last Trade Trade History
$21.2B
$670,000 0.0% of portfolio
1,600
Q3 2025 Reduced 74.6%
$23.2B
$661,000 0.0% of portfolio
7,800
Q3 2025 Added 8.33%
$26.4M
$632,000 0.0% of portfolio
780,982
Q3 2025 Added 37.97%
$63M
$585,000 0.0% of portfolio
417,900
Q3 2025 Reduced 13.96%
$1.38B
$579,000 0.0% of portfolio
11,800
Q3 2025 New
$2.39B
$545,000 0.0% of portfolio
13,600
Q3 2025 New
$37.5M
$538,000 0.0% of portfolio
266,700
Q3 2025 Reduced 10.14%
$137M
$538,000 0.0% of portfolio
74,200
Q3 2025 Added 22.4%
$423M
$528,000 0.0% of portfolio
385,546
Q3 2025 New
$21.6M
$511,000 0.0% of portfolio
288,800
Q3 2025 Added 34.7%
$156M
$482,000 0.0% of portfolio
228,600
Q3 2025 Added 62.94%
$227M
$481,000 0.0% of portfolio
242,200
Q3 2025 Added 67.5%
$61.8M
$465,000 0.0% of portfolio
234,041
Q3 2025 New
$27.7M
$428,000 0.0% of portfolio
857,600
Q3 2025 Added 133.61%
$122M
$422,000 0.0% of portfolio
243,100
Q3 2025 Reduced 33.78%
$91M
$399,000 0.0% of portfolio
192,900
Q3 2025 Added 118.21%
$146M
$371,000 0.0% of portfolio
257,784
Q3 2025 Added 57.68%
$313M
$345,000 0.0% of portfolio
127,849
Q3 2025 Added 3.9%
$22.1M
$340,000 0.0% of portfolio
267,900
Q3 2025 Reduced 0.63%
$5.54B
$333,000 0.0% of portfolio
3,300
Q3 2025 Reduced 65.98%
$109M
$332,000 0.0% of portfolio
80,900
Q3 2025 Reduced 14.75%
$56.3M
$326,000 0.0% of portfolio
213,500
Q3 2025 Added 27.23%
$32.7M
$314,000 0.0% of portfolio
196,376
Q3 2025 New
$411M
$304,000 0.0% of portfolio
40,500
Q3 2025 Reduced 62.67%
$2.06B
$301,000 0.0% of portfolio
8,700
Q3 2025 Added 16.0%
$274M
$298,000 0.0% of portfolio
51,500
Q3 2025 New
$55.6M
$298,000 0.0% of portfolio
222,700
Q3 2025 Reduced 1.02%
$833M
$289,000 0.0% of portfolio
117,656
Q3 2025 New
$1.5B
$284,000 0.0% of portfolio
15,100
Q3 2025 Reduced 3.82%
$472M
$281,000 0.0% of portfolio
39,324
Q3 2025 New
$451M
$274,000 0.0% of portfolio
31,500
Q3 2025 Reduced 61.63%
$155M
$270,000 0.0% of portfolio
58,600
Q3 2025 New
$83.1M
$262,000 0.0% of portfolio
112,677
Q3 2025 Added 704.84%
$960M
$256,000 0.0% of portfolio
77,900
Q3 2025 Reduced 6.82%
$4.4B
$254,000 0.0% of portfolio
2,700
Q3 2025 Reduced 98.61%
$131M
$233,000 0.0% of portfolio
182,071
Q3 2025 Reduced 65.89%
$390M
$221,000 0.0% of portfolio
37,300
Q3 2025 New
$247M
$221,000 0.0% of portfolio
42,600
Q3 2025 Added 7.58%
$495M
$217,000 0.0% of portfolio
61,815
Q3 2025 Reduced 68.99%
$49.6M
$210,000 0.0% of portfolio
239,400
Q3 2025 Added 261.09%
$351M
$203,000 0.0% of portfolio
21,100
Q3 2025 Reduced 85.39%
$92.2M
$194,000 0.0% of portfolio
151,800
Q3 2025 New
$467M
$169,000 0.0% of portfolio
14,200
Q3 2025 New
$315M
$157,000 0.0% of portfolio
72,400
Q3 2025 Reduced 59.6%
$838M
$157,000 0.0% of portfolio
22,500
Q3 2025 Reduced 34.78%
$20.8M
$129,000 0.0% of portfolio
34,200
Q3 2025 New
$255M
$127,000 0.0% of portfolio
40,000
Q3 2025 New
$266M
$116,000 0.0% of portfolio
38,300
Q3 2025 Reduced 92.65%
$158M
$114,000 0.0% of portfolio
52,524
Q3 2025 New
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David A. Siegel

David A. Siegel

David A. Siegel is the co-founder and CEO of Two Sigma Advisers, a successful investment firm that uses technology and data-driven approaches to investing. Siegel is known for his expertise in quantitative investing and his innovative approach to investing. He has generated strong returns for his clients over the long term.
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