Opaleye Management Inc. Portfolio Holdings

Opaleye Management Inc.

  • $418 Million
  • Q2 2025

Opaleye Management Inc. has filed its 13F form on August 15, 2025 for Q2 2025 where it was disclosed a total value porftolio of $418 Million distributed in 41 stocks.

Among their holdings, we can observe that their the top five positions include companies like: Harrow Health, Inc. with a value of $119M, Eton Pharmaceuticals, Inc. with a value of $40.8M, Immunome Inc. with a value of $32.8M, Liquidia Corp with a value of $30.8M, and Codexis, Inc. with a value of $30.7M.

Opaleye Management Inc. is based out at Boston, MA

Below you can find more details about Opaleye Management Inc. portfolio as well as his latest detailed transactions.

Portfolio value $418 Million
Healthcare: $418 Million

Stock Holdings Table Companies Only

Stock Market Cap. Holding Value (Reported) # of Shares. Last Trade Trade History
$943M
$119 Million 28.52% of portfolio
3,905,000
Q2 2025 Reduced 1.26%
$438M
$40.8 Million 9.75% of portfolio
2,860,000
Q2 2025 Added 0.28%
$120M
$32.8 Million 7.85% of portfolio
3,529,581
Q2 2025 Reduced 0.58%
$1.55B
$30.8 Million 7.37% of portfolio
2,475,000
Q2 2025 Added 9.51%
$187M
$30.7 Million 7.35% of portfolio
12,600,000
Q2 2025 Added 32.63%
$5.51B
$30 Million 7.18% of portfolio
475,000
Q2 2025 Reduced 3.06%
$3.94B
$19.3 Million 4.6% of portfolio
535,000
Q1 2025 Reduced 76.33%
$961M
$14.8 Million 3.54% of portfolio
1,595,000
Q1 2025 Reduced 63.27%
$361M
$12.4 Million 2.96% of portfolio
1,680,000
Q2 2025 Reduced 14.94%
$160M
$11.9 Million 2.84% of portfolio
4,110,000
Q2 2025 Added 114.72%
$1.6B
$8.55 Million 2.04% of portfolio
500,000
Q2 2025 New
$228M
$7.95 Million 1.9% of portfolio
1,000,000
Q2 2025 New
$326M
$6.43 Million 1.54% of portfolio
255,087
Q2 2025 Added 0.81%
$846M
$6.42 Million 1.54% of portfolio
490,000
Q2 2025 Added 24.05%
$533M
$6.38 Million 1.53% of portfolio
562,120
Q2 2025 Added 87.37%
$127M
$6.23 Million 1.49% of portfolio
588,797
Q2 2025 Added 49.06%
$181M
$4.36 Million 1.04% of portfolio
3,545,000
Q2 2025 Reduced 17.32%
$241M
$4.03 Million 0.96% of portfolio
903,442
Q2 2025 Added 94.29%
$3.09B
$3.86 Million 0.92% of portfolio
105,000
Q2 2025 New
$84.2M
$3.76 Million 0.9% of portfolio
2,209,998
Q4 2024 New
$34.6M
$2.59 Million 0.62% of portfolio
855,000
Q2 2025 Reduced 50.58%
$80.3M
$2.23 Million 0.53% of portfolio
1,924,300
Q2 2025 Reduced 3.06%
$428M
$2.13 Million 0.51% of portfolio
390,000
Q2 2025 Reduced 50.94%
$138M
$2.06 Million 0.49% of portfolio
389,519
Q2 2025 Reduced 11.47%
$20.2M
$1.2 Million 0.29% of portfolio
1,220,000
Q2 2025 Added 3.83%
$99M
$682,000 0.16% of portfolio
95,000
Q2 2025 Added 37.04%
$8.39M
$533,000 0.13% of portfolio
1,442,061
Q2 2025 New
$28.8M
$266,000 0.06% of portfolio
240,000
Q2 2025 Reduced 42.86%

Summary

  • Portfolio
  • No. of Stocks 41
  • Current Value $418 Million
  • Prior Value $418 Million
  • Filing
  • Period Q2 2025
  • Filing Date August 15, 2025
  • Form Type 13F-HR/A
  • Activity in Q2 2025
  • New Purchases 0 stocks
  • Additional Purchases 0 stocks
  • Sold out of 0 stocks
  • Reduced holdings in 0 stocks
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