Perceptive Advisors LLC Portfolio Holdings

Perceptive Advisors LLC

  • $44.8 Billion
  • Q3 2025

Perceptive Advisors LLC has filed its 13F form on November 14, 2025 for Q3 2025 where it was disclosed a total value porftolio of $44.8 Billion distributed in 93 stocks.

Among their holdings, we can observe that their the top five positions include companies like: Rhythm Pharmaceuticals, Inc. with a value of $42.3B, Ascendis Pharma A/S with a value of $216M, Arcellx, Inc. with a value of $203M, Celcuity Inc. with a value of $145M, and Nuvalent, Inc. with a value of $135M.

Examining the 13F form we can see an increase of $42.5B in the current position value, from $2.28B to 44.8B.

Perceptive Advisors LLC is based out at New York, NY

Below you can find more details about Perceptive Advisors LLC portfolio as well as his latest detailed transactions.

Portfolio value $44.8 Billion
Healthcare: $44.8 Billion

Stock Holdings Table

Stock Market Cap. Holding Value (Reported) # of Shares. Last Trade Trade History
$5.54B
$42.3 Billion 94.44% of portfolio
419,104,969
Q3 2025 Added 17,230.57%
$11.4B
$216 Million 0.48% of portfolio
1,088,501
Q3 2025 Added 12.93%
$3.94B
$203 Million 0.45% of portfolio
2,468,353
Q3 2025 Reduced 0.39%
$1.38B
$145 Million 0.32% of portfolio
2,956,319
Q3 2025 Added 81.01%
$4.15B
$135 Million 0.3% of portfolio
1,562,336
Q3 2025 Added 13.61%
$4.4B
$127 Million 0.28% of portfolio
1,353,093
Q3 2025 Added 91.07%
$743M
$122 Million 0.27% of portfolio
8,952,365
Q3 2025 Added 13.29%
$14.3B
$111 Million 0.25% of portfolio
7,368,461
Q3 2025 Added 121.18%
$26.2B
$101 Million 0.23% of portfolio
702,130
Q3 2025 Added 7.98%
$378M
$104 Million 0.23% of portfolio
12,626,103
Q2 2025 Added 0.36%
$2.21B
$90.7 Million 0.2% of portfolio
3,794,615
Q3 2025 Added 354.85%
$1.84B
$85.5 Million 0.19% of portfolio
2,020,000
Q3 2025 Reduced 27.69%
$778M
$79.9 Million 0.18% of portfolio
9,383,456
Q4 2024 Added 16.04%
$2.6B
$75.2 Million 0.17% of portfolio
3,100,902
Q3 2025 Added 170.36%
$4.15B
$68.4 Million 0.15% of portfolio
1,030,134
Q3 2025 Reduced 4.12%
$1.44B
$61.6 Million 0.14% of portfolio
3,795,894
Q3 2025 Reduced 18.19%
$10.6B
$55.9 Million 0.12% of portfolio
220,547
Q3 2025 Added 572.46%
$6.52B
$55.9 Million 0.12% of portfolio
524,088
Q3 2025 Reduced 90.48%
$2.52B
$53.9 Million 0.12% of portfolio
1,135,766
Q3 2025 Added 24.01%
$2.66B
$50.2 Million 0.11% of portfolio
6,370,851
Q3 2025 Reduced 14.06%
$191M
$46.8 Million 0.1% of portfolio
6,485,420
Q1 2024 Added 61.97%
$3.55B
$43.7 Million 0.1% of portfolio
1,587,890
Q3 2025 Reduced 25.73%
$8.46B
$36.1 Million 0.08% of portfolio
270,428
Q3 2025 Added 62.91%
$147B
$30.3 Million 0.07% of portfolio
310,000
Q3 2025 Added 10.71%
$1.15B
$31.5 Million 0.07% of portfolio
1,462,400
Q3 2025 Added 226.79%
$255M
$30.9 Million 0.07% of portfolio
9,680,185
Q3 2025 Added 38.41%
$11.9B
$25.5 Million 0.06% of portfolio
465,487
Q3 2025 New
$296M
$27 Million 0.06% of portfolio
5,222,311
Q3 2025 Added 28.89%
$193B
$23.3 Million 0.05% of portfolio
52,119
Q3 2025 Added 15.51%
$5.13B
$21.2 Million 0.05% of portfolio
123,000
Q3 2025 New
$288M
$21 Million 0.05% of portfolio
3,760,099
Q3 2025 Added 71.66%
$3.06B
$16.9 Million 0.04% of portfolio
1,153,468
Q3 2025 Reduced 11.51%
$5.99B
$18.1 Million 0.04% of portfolio
148,900
Q3 2025 Reduced 25.0%
$603M
$13.1 Million 0.03% of portfolio
1,416,149
Q3 2025 Added 29.09%
$1.02B
$10.4 Million 0.02% of portfolio
634,577
Q3 2025 New
$3.55B
$9.61 Million 0.02% of portfolio
169,796
Q3 2025 Reduced 19.19%
$227M
$10.6 Million 0.02% of portfolio
12,594,211
Q4 2023 Added 38.23%
$255M
$10 Million 0.02% of portfolio
3,812,797
Q3 2025 New
$2.54B
$8.06 Million 0.02% of portfolio
200,791
Q2 2025 Reduced 38.28%
$408M
$10.3 Million 0.02% of portfolio
1,438,595
Q2 2025 New
$975M
$6.84 Million 0.02% of portfolio
540,444
Q3 2025 Reduced 75.95%
$1.22B
$7.15 Million 0.02% of portfolio
292,686
Q2 2025 Reduced 69.84%
$158M
$2.57 Million 0.01% of portfolio
1,178,307
Q3 2025 New
$155M
$3.3 Million 0.01% of portfolio
583,142
Q3 2025 Added 16.63%
$20.2M
$4.24 Million 0.01% of portfolio
4,325,000
Q1 2025 New
$2.9B
$3.68 Million 0.01% of portfolio
49,788
Q3 2025 New
$5.29B
$6.18 Million 0.01% of portfolio
35,000
Q3 2025 New
$112M
$3.83 Million 0.01% of portfolio
829,870
Q3 2025 New
$3.05B
$2.7 Million 0.01% of portfolio
105,597
Q3 2025 Reduced 72.26%

Summary

  • Portfolio
  • No. of Stocks 93
  • Current Value $44.8 Billion
  • Prior Value $2.28 Billion
  • Filing
  • Period Q3 2025
  • Filing Date November 14, 2025
  • Form Type 13F-HR
  • Activity in Q3 2025
  • New Purchases 20 stocks
  • Additional Purchases 30 stocks
  • Sold out of 0 stocks
  • Reduced holdings in 19 stocks
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