Virtus Investment Advisers, Inc. Biotechnology

Virtus Investment Advisers, Inc.

$289 Million
Q1 2025

Stock List

Stock	Market Cap.	Holding Value (Reported)	# of Shares.	Last Trade	Trade History
INCY Incyte Corp	$15.7B	$1.48 Million 0.51% of portfolio	24,495	Q1 2025 New
SAGE Sage Therapeutics, Inc.	$521M	$503,000 0.17% of portfolio	63,321	Q1 2025 New
ZLAB Zai Lab LTD	$3.7B	$485,000 0.17% of portfolio	13,435	Q1 2025 New
HALO Halozyme Therapeutics, Inc.	$8.19B	$478,000 0.17% of portfolio	7,505	Q1 2025 Added 241.76%
TGTX Tg Therapeutics, Inc.	$5.31B	$461,000 0.16% of portfolio	11,697	Q1 2025 New
BGNE Bei Gene, Ltd.	$23.5B	$450,000 0.16% of portfolio	1,989	Q1 2025 New
BBIO Bridge Bio Pharma, Inc.	$6.77B	$448,000 0.16% of portfolio	12,978	Q1 2025 New
AXSM Axsome Therapeutics, Inc.	$4.5B	$443,000 0.15% of portfolio	3,806	Q1 2025 New
ASND Ascendis Pharma A/S	$9.39B	$428,000 0.15% of portfolio	2,747	Q1 2025 New
SWTX Spring Works Therapeutics, Inc.	$2.93B	$409,000 0.14% of portfolio	9,279	Q1 2025 New
ALNY Alnylam Pharmaceuticals, Inc.	$40.4B	$396,000 0.14% of portfolio	1,467	Q1 2025 New
MDGL Madrigal Pharmaceuticals, Inc.	$5.12B	$393,000 0.14% of portfolio	1,188	Q1 2025 New
PTCT Ptc Therapeutics, Inc.	$3.31B	$386,000 0.13% of portfolio	7,583	Q1 2025 New
BMRN Biomarin Pharmaceutical Inc	$11.1B	$382,000 0.13% of portfolio	5,416	Q1 2025 New
MIRM Mirum Pharmaceuticals, Inc.	$1.92B	$382,000 0.13% of portfolio	8,492	Q1 2025 New
ADMA Adma Biologics, Inc.	$3.4B	$381,000 0.13% of portfolio	19,230	Q1 2025 Added 28.37%
INSM Insmed Inc	$14B	$380,000 0.13% of portfolio	4,986	Q1 2025 New
EXEL Exelixis, Inc.	$14.4B	$376,000 0.13% of portfolio	10,209	Q1 2025 Reduced 21.47%
VRTX Vertex Pharmaceuticals Inc	$121B	$374,000 0.13% of portfolio	773	Q1 2025 New
HRMY Harmony Biosciences Holdings, Inc.	$2.17B	$373,000 0.13% of portfolio	11,268	Q1 2025 Added 213.0%
KRYS Krystal Biotech, Inc.	$3.85B	$372,000 0.13% of portfolio	2,068	Q1 2025 New
TARS Tarsus Pharmaceuticals, Inc.	$1.13B	$360,000 0.12% of portfolio	7,025	Q1 2025 New
TVTX Travere Therapeutics, Inc.	$1.02B	$359,000 0.12% of portfolio	20,046	Q1 2025 New
IBRX Immunity Bio, Inc.	$1.2B	$355,000 0.12% of portfolio	118,100	Q1 2025 New
BCRX Biocryst Pharmaceuticals Inc	$1.59B	$354,000 0.12% of portfolio	47,239	Q1 2025 New
IMCR Immunocore Holdings PLC	$1.55B	$351,000 0.12% of portfolio	11,847	Q1 2025 New
ACAD Acadia Pharmaceuticals Inc	$3.73B	$345,000 0.12% of portfolio	20,804	Q1 2025 Reduced 47.16%
BPMC Blueprint Medicines Corp	$7.73B	$343,000 0.12% of portfolio	3,878	Q1 2025 New
LEGN Legend Biotech Corp	$7.4B	$343,000 0.12% of portfolio	10,116	Q1 2025 New
RYTM Rhythm Pharmaceuticals, Inc.	$4.82B	$341,000 0.12% of portfolio	6,446	Q1 2025 New
ARDX Ardelyx, Inc.	$656M	$336,000 0.12% of portfolio	68,515	Q1 2025 New
LGND Ligand Pharmaceuticals Inc	$2.24B	$332,000 0.11% of portfolio	3,162	Q1 2025 New
TBPH Theravance Biopharma, Inc.	$743M	$324,000 0.11% of portfolio	36,379	Q1 2025 New
REGN Regeneron Pharmaceuticals, Inc.	$60.5B	$308,000 0.11% of portfolio	486	Q1 2025 New
UTHR United Therapeutics Corp	$13.9B	$306,000 0.11% of portfolio	994	Q1 2025 New
ROIV Roivant Sciences Ltd.	$8.02B	$304,000 0.11% of portfolio	30,219	Q1 2025 New
AUPH Aurinia Pharmaceuticals Inc.	$1.29B	$297,000 0.1% of portfolio	37,051	Q1 2025 Reduced 55.27%
IONS Ionis Pharmaceuticals Inc	$5.98B	$292,000 0.1% of portfolio	9,701	Q1 2025 New
FOLD Amicus Therapeutics, Inc.	$1.76B	$288,000 0.1% of portfolio	35,370	Q1 2025 Added 134.24%
PHAT Phathom Pharmaceuticals, Inc.	$355M	$281,000 0.1% of portfolio	44,964	Q1 2025 New
RARE Ultragenyx Pharmaceutical Inc.	$1.91B	$277,000 0.1% of portfolio	7,655	Q1 2025 New
AGIO Agios Pharmaceuticals, Inc.	$2.17B	$275,000 0.1% of portfolio	9,408	Q1 2025 New
BNTX Bio N Tech Se	$27.8B	$270,000 0.09% of portfolio	2,976	Q1 2025 New
CRSP Crispr Therapeutics Ag	$5.15B	$269,000 0.09% of portfolio	7,905	Q1 2025 New
XERS Xeris Biopharma Holdings, Inc.	$703M	$265,000 0.09% of portfolio	48,288	Q1 2025 New
NVAX Novavax Inc	$598M	$255,000 0.09% of portfolio	39,805	Q1 2025 New
APLS Apellis Pharmaceuticals, Inc.	$2.21B	$239,000 0.08% of portfolio	10,967	Q1 2025 New
MRNA Moderna, Inc.	$13.4B	$237,000 0.08% of portfolio	8,385	Q1 2025 New
AKRO Akero Therapeutics, Inc.	$2.34B	$228,000 0.08% of portfolio	5,654	Q1 2025 New
DAWN Day One Biopharmaceuticals, Inc.	$530M	$222,000 0.08% of portfolio	28,030	Q1 2025 New

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