California State Teachers Retirement System Biotechnology

California State Teachers Retirement System

$87.4 Billion
Q2 2025

Stock List

Stock	Market Cap.	Holding Value (Reported)	# of Shares.	Last Trade	Trade History
VRTX Vertex Pharmaceuticals Inc	$99.5B	$177 Million 0.2% of portfolio	397,640	Q2 2025 Reduced 0.21%
REGN Regeneron Pharmaceuticals, Inc.	$59.7B	$86.2 Million 0.1% of portfolio	164,123	Q2 2025 Reduced 1.19%
ALNY Alnylam Pharmaceuticals, Inc.	$52.9B	$65 Million 0.07% of portfolio	199,316	Q2 2025 Added 0.95%
RPRX Royalty Pharma PLC	$15.7B	$24 Million 0.03% of portfolio	666,408	Q2 2025 Reduced 23.08%
INSM Insmed Inc	$16.5B	$17.5 Million 0.02% of portfolio	173,529	Q2 2025 Added 10.04%
UTHR United Therapeutics Corp	$13.7B	$17.3 Million 0.02% of portfolio	60,327	Q2 2025 Reduced 5.31%
INCY Incyte Corp	$18.2B	$17.1 Million 0.02% of portfolio	250,761	Q2 2025 Added 9.22%
BMRN Biomarin Pharmaceutical Inc	$10.6B	$13.2 Million 0.02% of portfolio	239,323	Q2 2025 Reduced 13.34%
EXEL Exelixis, Inc.	$12.1B	$10.5 Million 0.01% of portfolio	237,369	Q2 2025 Reduced 3.38%
MRNA Moderna, Inc.	$10B	$9.03 Million 0.01% of portfolio	327,429	Q2 2025 Reduced 34.01%
BPMC Blueprint Medicines Corp	$7.73B	$8.19 Million 0.01% of portfolio	63,898	Q2 2025 Added 9.06%
TECH Bio Techne Corp	$2.07B	$7.54 Million 0.01% of portfolio	146,634	Q2 2025 Reduced 40.84%
CORT Corcept Therapeutics Inc	$7.88B	$6.68 Million 0.01% of portfolio	90,982	Q2 2025 Added 0.95%
HALO Halozyme Therapeutics, Inc.	$8.95B	$6.31 Million 0.01% of portfolio	121,300	Q1 2025 Added 2.52%
BBIO Bridge Bio Pharma, Inc.	$7.28B	$5.78 Million 0.01% of portfolio	133,891	Q2 2025 Added 10.22%
JAZZ Jazz Pharmaceuticals PLC	$7.1B	$5.77 Million 0.01% of portfolio	54,374	Q1 2025 Reduced 1.17%
IONS Ionis Pharmaceuticals Inc	$5.85B	$5.73 Million 0.01% of portfolio	145,104	Q2 2025 Added 9.73%
TGTX Tg Therapeutics, Inc.	$3.94B	$5.38 Million 0.01% of portfolio	149,512	Q2 2025 Added 10.32%
RVMD Revolution Medicines, Inc.	$3.09B	$5.15 Million 0.01% of portfolio	140,077	Q2 2025 Added 0.31%
MDGL Madrigal Pharmaceuticals, Inc.	$6.14B	$4.28 Million 0.0% of portfolio	14,133	Q2 2025 Added 14.38%
ADMA Adma Biologics, Inc.	$3.29B	$3.91 Million 0.0% of portfolio	214,545	Q2 2025 Reduced 10.16%
ROIV Roivant Sciences Ltd.	$8.15B	$3.79 Million 0.0% of portfolio	336,407	Q2 2025 Reduced 0.88%
CRSP Crispr Therapeutics Ag	$4.42B	$3.64 Million 0.0% of portfolio	74,907	Q2 2025 Added 7.41%
AXSM Axsome Therapeutics, Inc.	$4.51B	$3.58 Million 0.0% of portfolio	34,313	Q2 2025 Added 17.49%
PCVX Vaxcyte, Inc.	$1.78B	$3.48 Million 0.0% of portfolio	107,050	Q1 2025 Added 1.9%
CYTK Cytokinetics Inc	$3.23B	$3.42 Million 0.0% of portfolio	103,635	Q2 2025 Added 0.12%
PTCT Ptc Therapeutics, Inc.	$3.24B	$3.15 Million 0.0% of portfolio	64,524	Q2 2025 Added 0.15%
NUVL Nuvalent, Inc.	$3.29B	$3.07 Million 0.0% of portfolio	40,183	Q2 2025 Added 22.35%
AKRO Akero Therapeutics, Inc.	$2.23B	$3.01 Million 0.0% of portfolio	56,451	Q2 2025 Added 21.03%
PTGX Protagonist Therapeutics, Inc	$2.68B	$2.83 Million 0.0% of portfolio	51,195	Q2 2025 Added 22.31%
RARE Ultragenyx Pharmaceutical Inc.	$1.97B	$2.81 Million 0.0% of portfolio	77,159	Q2 2025 Added 0.21%
KRYS Krystal Biotech, Inc.	$3.69B	$2.77 Million 0.0% of portfolio	20,126	Q1 2025 Reduced 1.29%
RYTM Rhythm Pharmaceuticals, Inc.	$5.51B	$2.71 Million 0.0% of portfolio	42,917	Q2 2025 Added 0.46%
SWTX Spring Works Therapeutics, Inc.	$2.93B	$2.62 Million 0.0% of portfolio	55,749	Q2 2025 Added 0.68%
RNA Avidity Biosciences, Inc.	$2.41B	$2.56 Million 0.0% of portfolio	90,258	Q2 2025 Added 0.52%
VKTX Viking Therapeutics, Inc.	$3.06B	$2.46 Million 0.0% of portfolio	92,823	Q2 2025 Added 0.62%
SRRK Scholar Rock Holding Corp	$1.66B	$2.21 Million 0.0% of portfolio	62,372	Q2 2025 Added 0.93%
ACAD Acadia Pharmaceuticals Inc	$4.12B	$2.17 Million 0.0% of portfolio	100,691	Q2 2025 Added 1.42%
CRNX Crinetics Pharmaceuticals, Inc.	$1.53B	$2.17 Million 0.0% of portfolio	75,484	Q2 2025 Added 0.65%
LGND Ligand Pharmaceuticals Inc	$2.58B	$2.17 Million 0.0% of portfolio	19,091	Q2 2025 Added 1.56%
MRUS Merus N.V.	$2.93B	$2.16 Million 0.0% of portfolio	41,149	Q2 2024 Reduced 12.63%
CPRX Catalyst Pharmaceuticals, Inc.	$2.09B	$2.15 Million 0.0% of portfolio	99,257	Q2 2025 Added 1.01%
IMVT Immunovant, Inc.	$3.55B	$2.04 Million 0.0% of portfolio	74,314	Q1 2025 Added 53.54%
ACLX Arcellx, Inc.	$3.19B	$1.98 Million 0.0% of portfolio	30,087	Q2 2025 Reduced 0.82%
VCEL Vericel Corp	$1.72B	$1.93 Million 0.0% of portfolio	45,404	Q2 2025 Added 0.85%
VCYT Veracyte, Inc.	$2.06B	$1.92 Million 0.0% of portfolio	71,095	Q2 2025 Added 0.8%
XENE Xenon Pharmaceuticals Inc.	$2.24B	$1.89 Million 0.0% of portfolio	60,233	Q2 2025 Added 8.54%
IDYA Ideaya Biosciences, Inc.	$1.13B	$1.73 Million 0.0% of portfolio	82,532	Q2 2025 Added 1.54%
MIRM Mirum Pharmaceuticals, Inc.	$2.38B	$1.71 Million 0.0% of portfolio	33,574	Q2 2025 Added 2.33%
RXRX Recursion Pharmaceuticals, Inc.	$976M	$1.68 Million 0.0% of portfolio	332,187	Q2 2025 Added 44.32%

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