Wellington Management Group LLP Biotechnology

Wellington Management Group LLP

$557 Billion
Q3 2024

Stock List

Stock	Market Cap.	Holding Value (Reported)	# of Shares.	Last Trade	Trade History
VRTX Vertex Pharmaceuticals Inc	$104B	$2.23 Billion 0.4% of portfolio	4,798,870	Q3 2024 Added 17.2%
ALNY Alnylam Pharmaceuticals, Inc.	$28.7B	$1.36 Billion 0.24% of portfolio	4,953,347	Q3 2024 Reduced 20.24%
UTHR United Therapeutics Corp	$16.4B	$1.14 Billion 0.2% of portfolio	3,170,849	Q3 2024 Reduced 3.48%
RVMD Revolution Medicines, Inc.	$3.84B	$517 Million 0.09% of portfolio	11,401,394	Q3 2024 Reduced 16.54%
PCVX Vaxcyte, Inc.	$4.94B	$515 Million 0.09% of portfolio	4,513,756	Q3 2024 Reduced 1.73%
REGN Regeneron Pharmaceuticals, Inc.	$76.7B	$463 Million 0.08% of portfolio	440,609	Q3 2024 Reduced 58.5%
APLS Apellis Pharmaceuticals, Inc.	$3.51B	$449 Million 0.08% of portfolio	15,566,969	Q3 2024 Reduced 5.01%
CYTK Cytokinetics Inc	$4.43B	$411 Million 0.07% of portfolio	7,774,970	Q3 2024 Added 3.53%
BPMC Blueprint Medicines Corp	$5.21B	$367 Million 0.07% of portfolio	3,964,610	Q3 2024 Added 22.53%
IONS Ionis Pharmaceuticals Inc	$4.96B	$350 Million 0.06% of portfolio	8,735,787	Q3 2024 Added 32.99%
MRNA Moderna, Inc.	$16.4B	$349 Million 0.06% of portfolio	5,224,685	Q3 2024 Added 20.98%
SRPT Sarepta Therapeutics, Inc.	$10.9B	$341 Million 0.06% of portfolio	2,726,613	Q3 2024 Added 32.26%
RNA Avidity Biosciences, Inc.	$1.52B	$323 Million 0.06% of portfolio	7,030,949	Q3 2024 Added 84.93%
CLDX Celldex Therapeutics, Inc.	$1.18B	$314 Million 0.06% of portfolio	9,243,599	Q3 2024 Added 14.46%
DNLI Denali Therapeutics Inc.	$2.73B	$312 Million 0.06% of portfolio	10,727,450	Q3 2024 Added 9.2%
PTCT Ptc Therapeutics, Inc.	$3.23B	$293 Million 0.05% of portfolio	7,892,799	Q3 2024 Reduced 3.85%
ARGX Argenx Se	$34.3B	$262 Million 0.05% of portfolio	482,346	Q3 2024 Added 13.03%
FOLD Amicus Therapeutics, Inc.	$2.64B	$256 Million 0.05% of portfolio	23,964,044	Q3 2024 Added 13.53%
RARE Ultragenyx Pharmaceutical Inc.	$2.95B	$231 Million 0.04% of portfolio	4,165,424	Q3 2024 Reduced 8.58%
CRNX Crinetics Pharmaceuticals, Inc.	$2.77B	$228 Million 0.04% of portfolio	4,459,691	Q3 2024 Reduced 3.48%
AKRO Akero Therapeutics, Inc.	$1.29B	$227 Million 0.04% of portfolio	7,896,632	Q3 2024 Added 54.39%
IMCR Immunocore Holdings PLC	$1.29B	$219 Million 0.04% of portfolio	7,048,833	Q3 2024 Added 10.48%
KYMR Kymera Therapeutics, Inc.	$2.2B	$219 Million 0.04% of portfolio	4,618,359	Q3 2024 Added 7.17%
RCKT Rocket Pharmaceuticals, Inc.	$951M	$208 Million 0.04% of portfolio	11,242,144	Q3 2024 Added 22.79%
ZLAB Zai Lab LTD	$2.56B	$204 Million 0.04% of portfolio	8,436,606	Q3 2024 Added 18.42%
ASND Ascendis Pharma A/S	$7.68B	$188 Million 0.03% of portfolio	1,261,480	Q3 2024 Reduced 51.72%
XENE Xenon Pharmaceuticals Inc.	$2.44B	$151 Million 0.03% of portfolio	3,843,447	Q3 2024 Added 0.4%
MRUS Merus N.V.	$1.93B	$144 Million 0.03% of portfolio	2,887,514	Q3 2024 Added 73.64%
VCYT Veracyte, Inc.	$2.83B	$144 Million 0.03% of portfolio	4,232,844	Q3 2024 Reduced 38.44%
TECH Bio Techne Corp	$2.8B	$122 Million 0.02% of portfolio	1,532,589	Q3 2024 Reduced 8.8%
IMTX Immatics N.V.	$542M	$110 Million 0.02% of portfolio	9,681,183	Q3 2024 Added 1.52%
NUVL Nuvalent, Inc.	$3.36B	$104 Million 0.02% of portfolio	1,011,837	Q3 2024 Added 65.49%
LEGN Legend Biotech Corp	$5.81B	$99.2 Million 0.02% of portfolio	2,036,370	Q3 2024 Reduced 27.52%
SNDX Syndax Pharmaceuticals Inc	$748M	$96 Million 0.02% of portfolio	4,985,976	Q3 2024 Reduced 32.06%
AUTL Autolus Therapeutics PLC	$214M	$87.9 Million 0.02% of portfolio	24,220,226	Q3 2024 Added 35.39%
NRIX Nurix Therapeutics, Inc.	$888M	$78.2 Million 0.01% of portfolio	3,482,105	Q3 2024 Added 8.75%
INSM Insmed Inc	$9.35B	$70.3 Million 0.01% of portfolio	962,459	Q3 2024 Added 2.56%
PRTA Prothena Corp Public LTD CO	$641M	$69.9 Million 0.01% of portfolio	4,178,788	Q3 2024 Added 14.82%
AXSM Axsome Therapeutics, Inc.	$3.63B	$66.7 Million 0.01% of portfolio	742,745	Q3 2024 Added 1.11%
GERN Geron Corp	$1.34B	$57.5 Million 0.01% of portfolio	12,662,404	Q3 2024 Added 4.72%
GMAB Genmab A/S	$13.8B	$56.2 Million 0.01% of portfolio	2,306,250	Q3 2024 Reduced 0.03%
VRNA Verona Pharma PLC	$2.83B	$54 Million 0.01% of portfolio	1,878,632	Q3 2024 Added 19.55%
LBPH Longboard Pharmaceuticals, Inc.	$815M	$53 Million 0.01% of portfolio	1,590,072	Q3 2024 Reduced 10.62%
NVO Novo Nordisk A S	$198B	$42 Million 0.01% of portfolio	352,878	Q3 2024 New
SVRA Savara Inc	$350M	$36.6 Million 0.01% of portfolio	8,624,012	Q3 2024 Added 22.93%
VCEL Vericel Corp	$2.59B	$24.8 Million 0.0% of portfolio	587,857	Q3 2024 Added 214.04%
TRDA Entrada Therapeutics, Inc.	$548M	$16.5 Million 0.0% of portfolio	1,029,369	Q3 2024 Reduced 0.44%
NTLA Intellia Therapeutics, Inc.	$886M	$13.2 Million 0.0% of portfolio	644,763	Q3 2024 Reduced 17.53%
OLMA Olema Pharmaceuticals, Inc.	$236M	$12 Million 0.0% of portfolio	1,002,685	Q3 2024 Added 10.76%
DAWN Day One Biopharmaceuticals, Inc.	$931M	$10.1 Million 0.0% of portfolio	721,581	Q3 2024 Added 142.11%

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